NO20000285L - Terapeutisk eller profylaktisk middel for glomerulopati - Google Patents
Terapeutisk eller profylaktisk middel for glomerulopatiInfo
- Publication number
- NO20000285L NO20000285L NO20000285A NO20000285A NO20000285L NO 20000285 L NO20000285 L NO 20000285L NO 20000285 A NO20000285 A NO 20000285A NO 20000285 A NO20000285 A NO 20000285A NO 20000285 L NO20000285 L NO 20000285L
- Authority
- NO
- Norway
- Prior art keywords
- diyl
- lower alkyl
- thiophen
- optionally substituted
- phenyl
- Prior art date
Links
- 208000022461 Glomerular disease Diseases 0.000 title abstract 2
- 230000000069 prophylactic effect Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- -1 2,5-thiophendiyl Chemical group 0.000 abstract 10
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 125000004414 alkyl thio group Chemical group 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 125000001072 heteroaryl group Chemical group 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004104 aryloxy group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000000043 benzamido group Chemical group [H]N([*])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000005415 substituted alkoxy group Chemical group 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
- C07C311/44—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19541497 | 1997-07-22 | ||
| PCT/JP1998/003226 WO1999004780A1 (fr) | 1997-07-22 | 1998-07-17 | Agent therapeutique ou prophylactique de traitement de la glomerulopathie |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20000285D0 NO20000285D0 (no) | 2000-01-20 |
| NO20000285L true NO20000285L (no) | 2000-03-22 |
Family
ID=16340702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000285A NO20000285L (no) | 1997-07-22 | 2000-01-20 | Terapeutisk eller profylaktisk middel for glomerulopati |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6423729B1 (fr) |
| EP (2) | EP1398027B1 (fr) |
| JP (1) | JP3621427B2 (fr) |
| KR (1) | KR100386148B1 (fr) |
| CN (1) | CN1198607C (fr) |
| AT (1) | ATE320801T1 (fr) |
| AU (1) | AU737218B2 (fr) |
| BR (1) | BR9811521A (fr) |
| CA (1) | CA2297011C (fr) |
| DE (2) | DE69836877D1 (fr) |
| HU (1) | HUP0003851A3 (fr) |
| ID (2) | ID24105A (fr) |
| IL (1) | IL133933A0 (fr) |
| NO (1) | NO20000285L (fr) |
| NZ (1) | NZ502274A (fr) |
| PL (1) | PL338235A1 (fr) |
| RU (1) | RU2207849C2 (fr) |
| SK (1) | SK262000A3 (fr) |
| TR (2) | TR200100389T2 (fr) |
| TW (2) | TW593249B (fr) |
| WO (1) | WO1999004780A1 (fr) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2207849C2 (ru) * | 1997-07-22 | 2003-07-10 | Шионоги & Ко., Лтд. | Композиция для лечения и профилактики гломерулопатии, новые соединения, в нее входящие, фармацевтическая композиция для ингибирования матриксных металлопротеиназ и композиция для ингибирования коллагеназ типа iv |
| US6410580B1 (en) | 1998-02-04 | 2002-06-25 | Novartis Ag | Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases |
| TR200002224T2 (tr) | 1998-02-04 | 2000-12-21 | Novartis Ag | Matris-bozucu metalloproteinasları inhibe eden sülfonilamino türevleri. |
| AU5647099A (en) * | 1998-09-11 | 2000-04-03 | Shionogi & Co., Ltd. | Remedal or preventive agent for congestive heart failure |
| PL351374A1 (en) * | 1999-04-19 | 2003-04-07 | Shionogi & Co | Sulfonamide derivatives having oxadiazole rings |
| FR2798589B1 (fr) * | 1999-09-16 | 2001-11-30 | Oreal | Composition cosmetique comprenant au moins un copolymere silicone/acrylate et au moins un agent epaississant |
| EP1270569A4 (fr) | 2000-01-26 | 2005-01-05 | Shionogi & Co | Derives de tryptophane substitue |
| EP1280764B1 (fr) * | 2000-03-24 | 2010-11-24 | Methylgene, Inc. | Inhibiteurs d'histone desacetylase |
| HUP0300619A3 (en) * | 2000-04-21 | 2006-02-28 | Shionogi & Co | Pharmaceutical compositions containing oxadiazole derivatives having anticancer effects |
| AU2001248765A1 (en) * | 2000-04-21 | 2001-11-12 | Shionogi And Co., Ltd. | Oxadiazole derivatives having therapeutic or preventive efficacies against glomerular disorders |
| AU2001248820A1 (en) * | 2000-04-28 | 2001-11-12 | Shionogi And Co., Ltd. | Thiazole and oxazole derivatives |
| WO2001083431A1 (fr) | 2000-04-28 | 2001-11-08 | Shionogi & Co., Ltd. | Inhibiteurs de mmp-12 |
| KR20030030036A (ko) * | 2000-09-29 | 2003-04-16 | 시오노기세이야쿠가부시키가이샤 | 티아졸 또는 옥사졸 유도체 |
| KR20050034603A (ko) | 2001-10-09 | 2005-04-14 | 3-디멘져널 파마슈티칼즈 인코오포레이티드 | 치환된 디페닐옥사졸, 이의 합성 및 이의 형광프로브로서의 용도 |
| JP4427328B2 (ja) * | 2001-12-14 | 2010-03-03 | エクセリクシス， インク． | ヒト−ａｄａｍ−１０インヒビター |
| ES2323527T3 (es) | 2002-05-29 | 2009-07-20 | MERCK & CO., INC. | Compuestos utiles en el tratamiento del carbunco y en la inhibicion del factor letal. |
| WO2005012268A1 (fr) | 2003-07-30 | 2005-02-10 | Shionogi & Co., Ltd. | Derive sulfonamide comprenant un noyau isoxazole |
| US7504431B2 (en) * | 2004-04-16 | 2009-03-17 | Bristol-Myers Squibb Company | Sulfonyl amide inhibitors of calcium channel function |
| EP1747212A4 (fr) | 2004-05-11 | 2009-03-25 | Merck & Co Inc | Procede de fabrication de derives d'acides amines n-sulfones |
| JP2006036691A (ja) * | 2004-07-27 | 2006-02-09 | Shionogi & Co Ltd | 腎炎の治療または予防剤 |
| US20080119513A1 (en) * | 2004-09-06 | 2008-05-22 | Fumihiko Watanabe | Sulfonamide Derivative Selectively Inhibiting Mmp-13 |
| US7576222B2 (en) | 2004-12-28 | 2009-08-18 | Wyeth | Alkynyl-containing tryptophan derivative inhibitors of TACE/matrix metalloproteinase |
| EP1997804A1 (fr) | 2006-03-03 | 2008-12-03 | Shionogi & Co., Ltd. | Inhibiteur selectif de mmp-13 |
| JPWO2008053913A1 (ja) | 2006-11-02 | 2010-02-25 | 塩野義製薬株式会社 | Ｍｍｐ−１３を選択的に阻害するスルホニルウレア誘導体 |
| MX339096B (es) * | 2008-12-23 | 2016-05-11 | Aquilus Pharmaceuticals Inc | Compuestos inhibidores de metaloproteasa a base de feniletiniltiofeno y su uso en el tratamiento del dolor y otras enfermedades. |
| CA3072854A1 (fr) | 2017-08-17 | 2019-02-21 | Glaxosmithkline Intellectual Property Development Limited | Nouveaux composes de tetrazole et leur utilisation dans le traitement de la tuberculose |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5506242A (en) | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
| JP3818322B2 (ja) | 1994-04-28 | 2006-09-06 | 敏一 中村 | コラーゲン分解促進剤 |
| CA2193691A1 (fr) | 1994-06-22 | 1995-12-28 | Andrew Miller | Inhibiteurs de metalloproteinases |
| KR980009238A (ko) * | 1995-07-28 | 1998-04-30 | 우에노 도시오 | 설포닐아미노산 유도체 |
| KR19990036271A (ko) | 1995-08-08 | 1999-05-25 | 토마스 네프 | 콜라겐 과다생산과 연관된 질환의 치료에 이용되는 ｃ-프로테나제 저해물질 |
| DK0757984T3 (da) * | 1995-08-08 | 2003-03-03 | Ono Pharmaceutical Co | Hydroxamsyrederivater, der kan anvendes til inhibering af gelatinase |
| JPH09110864A (ja) * | 1995-08-10 | 1997-04-28 | Kureha Chem Ind Co Ltd | クロモン誘導体、その製造方法及び医薬組成物 |
| JPH0987178A (ja) | 1995-09-22 | 1997-03-31 | Toyama Chem Co Ltd | 神経成長因子の作用増強剤 |
| JPH0987176A (ja) | 1995-09-26 | 1997-03-31 | Shiseido Co Ltd | 糸球体腎炎抑制剤 |
| ES2284180T3 (es) * | 1996-01-23 | 2007-11-01 | SHIONOGI & CO., LTD. | Derivados de aminoacidos sulfonados e inhibidores de metaloproteinasas que contienen los mismos. |
| CA2242416C (fr) * | 1996-01-23 | 2006-03-21 | Shionogi & Co., Ltd. | Derives d'acides amines sulfones et inhibiteurs de metalloproteinases contenant ces derives |
| DE69707865T2 (de) | 1996-05-17 | 2002-05-02 | Warner-Lambert Co., Morris Plains | Biphenylsulfonamid matrix metalloproteinase inhibitoren |
| AU2792097A (en) | 1996-05-24 | 1998-01-05 | Ono Pharmaceutical Co. Ltd. | Phenylsulfonamide derivatives |
| AU740263C (en) * | 1996-07-22 | 2002-05-16 | Monsanto Company | Thiol sulfonamide metalloprotease inhibitors |
| JP2001521504A (ja) * | 1997-04-01 | 2001-11-06 | アグロン・ファーマシュウティカルズ・インコーポレーテッド | メタロプロテイナーゼ阻害薬、それらを含有する薬剤組成物および薬剤としてのそれらの使用 |
| RU2207849C2 (ru) * | 1997-07-22 | 2003-07-10 | Шионоги & Ко., Лтд. | Композиция для лечения и профилактики гломерулопатии, новые соединения, в нее входящие, фармацевтическая композиция для ингибирования матриксных металлопротеиназ и композиция для ингибирования коллагеназ типа iv |
-
1998
- 1998-07-17 RU RU2000103032/04A patent/RU2207849C2/ru not_active IP Right Cessation
- 1998-07-17 TR TR2001/00389T patent/TR200100389T2/xx unknown
- 1998-07-17 SK SK26-2000A patent/SK262000A3/sk unknown
- 1998-07-17 CA CA002297011A patent/CA2297011C/fr not_active Expired - Fee Related
- 1998-07-17 KR KR10-2000-7000676A patent/KR100386148B1/ko not_active IP Right Cessation
- 1998-07-17 JP JP50964999A patent/JP3621427B2/ja not_active Expired - Fee Related
- 1998-07-17 EP EP03023547A patent/EP1398027B1/fr not_active Expired - Lifetime
- 1998-07-17 AT AT98932574T patent/ATE320801T1/de not_active IP Right Cessation
- 1998-07-17 HU HU0003851A patent/HUP0003851A3/hu unknown
- 1998-07-17 CN CNB98809147XA patent/CN1198607C/zh not_active Expired - Fee Related
- 1998-07-17 IL IL13393398A patent/IL133933A0/xx unknown
- 1998-07-17 US US09/462,001 patent/US6423729B1/en not_active Expired - Fee Related
- 1998-07-17 AU AU82439/98A patent/AU737218B2/en not_active Ceased
- 1998-07-17 WO PCT/JP1998/003226 patent/WO1999004780A1/fr active IP Right Grant
- 1998-07-17 DE DE69836877T patent/DE69836877D1/de not_active Expired - Lifetime
- 1998-07-17 ID IDW20000054A patent/ID24105A/id unknown
- 1998-07-17 BR BR9811521-9A patent/BR9811521A/pt not_active Application Discontinuation
- 1998-07-17 PL PL98338235A patent/PL338235A1/xx unknown
- 1998-07-17 EP EP98932574A patent/EP1029541B1/fr not_active Expired - Lifetime
- 1998-07-17 ID IDW00200101551A patent/ID29293A/id unknown
- 1998-07-17 TR TR2000/00214T patent/TR200000214T2/xx unknown
- 1998-07-17 NZ NZ502274A patent/NZ502274A/xx unknown
- 1998-07-17 DE DE69833940T patent/DE69833940T2/de not_active Expired - Lifetime
- 1998-09-30 TW TW087111798A patent/TW593249B/zh not_active IP Right Cessation
- 1998-09-30 TW TW092118405A patent/TWI249518B/zh not_active IP Right Cessation
-
2000
- 2000-01-20 NO NO20000285A patent/NO20000285L/no not_active Application Discontinuation
-
2002
- 2002-06-06 US US10/162,865 patent/US6878739B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20000285D0 (no) | Terapeutisk eller profylaktisk middel for glomerulopati | |
| HUT43238A (en) | Herbicidal compositions comprising substituted piridine-sulfonamide derivatives as active substance and process for preparing the active substances | |
| ATE431347T1 (de) | Neue heterocyclylmethyl-substituierte pyrazolderivate und ihre verwendung in der behandlung von herz-kreislauf-erkrankungen | |
| ATE369337T1 (de) | Neue bizyklische verbindungen | |
| EP1054005A4 (fr) | Derives de sulfamide, leur procede de production et leur utilisation | |
| JP2002508362A5 (ja) | １−置換−１−アミノメチル−シクロアルカン誘導体（＝ガバペンチン類縁体） | |
| DK0920430T3 (da) | Purinderivater og deres anvendelse som antikoaguleringsmidler | |
| ID28806A (id) | Turunan-turunan karboksamida heterosiklik yang mengandung nitrogen atau garam-garam daripadanya dan zat-zat antivirus yang terdiri dari senyawa ini | |
| ATE271868T1 (de) | Neue cathechole als antimikrobielle mittel | |
| NO20014925D0 (no) | Farmasöytiske forbindelser | |
| PT2113502E (pt) | Compostos do tipo hidrazida e sua utilização em composições farmacêuticas para o tratamento das doenças cardiovasculares | |
| DE60005689D1 (de) | Neue aminobenzophenone | |
| JPS5553288A (en) | Heterocyclic derivative*its manufacture and medical composition containing it and having secretion controlling activity | |
| DE60238056D1 (de) | Verfahren zum kristallisieren von reduziertem coenzym q10 aus wässriger lösung | |
| DE69811689D1 (de) | Kondensierte imidazolderivate zur erhöhung der oralen bioverfügbarkeit von pharmazeutika | |
| ES2180201T3 (es) | Derivados de azetidinona para el tratamiento de infecciones por hcmv. | |
| SE9704770D0 (sv) | New use | |
| ATE274508T1 (de) | Aminophenolderivate | |
| DE60013515D1 (de) | 4-Arylpiperidinderivate zur Behandlung von Pruritus | |
| RU2002101136A (ru) | Средства для лечения и профилактики неоплазм | |
| NO20051774L (no) | Taksanderivater funksjonalisert pa den 14.posisjon og en fremgangsmate for fremstilling derav | |
| WO2002088091A3 (fr) | Inhibiteurs de la cysteine protease 2a du rhinovirus humain | |
| DE60208554D1 (de) | Neue aliphatische verbindung, syntheseverfahren und anwendungsverfahren | |
| DE69904051D1 (de) | Zubereitung enthaltend derivate von phenylaminothiophenessigsäure zur behandlung der akuten respiratorischen insuffizienz (ards) und der akuten respiratorischen insuffizienz bei kindern (irds) | |
| MXPA01011888A (es) | Derivados de tetrazolinona. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |