NO177851C - Analogifremgangsmåte for fremstilling av cyklometylen-1,2-bikarboksylsyreamider med terapeutisk aktivitet - Google Patents

Analogifremgangsmåte for fremstilling av cyklometylen-1,2-bikarboksylsyreamider med terapeutisk aktivitet

Info

Publication number
NO177851C
NO177851C NO891484A NO891484A NO177851C NO 177851 C NO177851 C NO 177851C NO 891484 A NO891484 A NO 891484A NO 891484 A NO891484 A NO 891484A NO 177851 C NO177851 C NO 177851C
Authority
NO
Norway
Prior art keywords
cyclomethylene
preparation
acid amides
therapeutic activity
analogous process
Prior art date
Application number
NO891484A
Other languages
English (en)
Norwegian (no)
Other versions
NO177851B (no
NO891484D0 (no
NO891484L (no
Inventor
Luigi Turbanti
Guido Cerbai
Marco Criscuoli
Original Assignee
Guidotti & C Spa Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guidotti & C Spa Labor filed Critical Guidotti & C Spa Labor
Publication of NO891484D0 publication Critical patent/NO891484D0/no
Publication of NO891484L publication Critical patent/NO891484L/no
Publication of NO177851B publication Critical patent/NO177851B/no
Publication of NO177851C publication Critical patent/NO177851C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/61—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Eyeglasses (AREA)
  • Polyamides (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
NO891484A 1988-04-12 1989-04-11 Analogifremgangsmåte for fremstilling av cyklometylen-1,2-bikarboksylsyreamider med terapeutisk aktivitet NO177851C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8820172A IT1224627B (it) 1988-04-12 1988-04-12 Ammidi di acidi ciclometilen_1,2_dicarbossilici adattivita' terapeutica, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono.

Publications (4)

Publication Number Publication Date
NO891484D0 NO891484D0 (no) 1989-04-11
NO891484L NO891484L (no) 1989-10-13
NO177851B NO177851B (no) 1995-08-28
NO177851C true NO177851C (no) 1995-12-06

Family

ID=11164400

Family Applications (1)

Application Number Title Priority Date Filing Date
NO891484A NO177851C (no) 1988-04-12 1989-04-11 Analogifremgangsmåte for fremstilling av cyklometylen-1,2-bikarboksylsyreamider med terapeutisk aktivitet

Country Status (28)

Country Link
US (1) US5095137A (it)
EP (1) EP0337348B1 (it)
JP (1) JPH026452A (it)
KR (1) KR900016097A (it)
CN (1) CN1037344A (it)
AT (1) ATE101126T1 (it)
AU (1) AU611796B2 (it)
BG (1) BG60556B1 (it)
CA (1) CA1314903C (it)
DD (1) DD294014A5 (it)
DE (1) DE68912811T2 (it)
DK (1) DK173689A (it)
ES (1) ES2061759T3 (it)
FI (1) FI891712A (it)
HU (1) HU206194B (it)
IL (1) IL89895A0 (it)
IN (2) IN169836B (it)
IT (1) IT1224627B (it)
MX (1) MX15635A (it)
NO (1) NO177851C (it)
NZ (1) NZ228688A (it)
PL (1) PL159413B1 (it)
PT (1) PT90254B (it)
RO (1) RO104347B1 (it)
RU (2) RU2004538C1 (it)
UA (1) UA15920A (it)
YU (1) YU73889A (it)
ZA (1) ZA892674B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1252708B (it) * 1991-12-23 1995-06-26 Guidotti & C Spa Labor Sali stabili dell'acido (+)-(1r,2s)-2((n-(2-idrossilammino-2-ossoetil)-n-metilammino)carbonil)cicloesan-1-carbossilico,ad attivita' ace inibitrice, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
US5977160A (en) * 1992-04-10 1999-11-02 Brigham And Women's Hospital, Inc. Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
IT1264860B1 (it) * 1993-06-21 1996-10-17 Guidotti & C Spa Labor Derivati di acidi cis- e trans-2(((2-(isdrossiammino)-2-ossoetil)- alchilammino)carbonil)cicloesancarbossilici
US5639746A (en) * 1994-12-29 1997-06-17 The Procter & Gamble Company Hydroxamic acid-containing inhibitors of matrix metalloproteases
US6028213A (en) * 1998-04-16 2000-02-22 Eastman Chemical Company Optically active cis-1,3-cyclohexanedicarboxylic acid monoesters with high enantiomeric purity and process for their preparation
WO2008012524A1 (en) * 2006-07-24 2008-01-31 Ucb Pharma S.A. Substituted aniline derivatives
US20100168243A1 (en) * 2007-06-20 2010-07-01 Baldwin John J Renin Inhibitors
WO2008156816A2 (en) 2007-06-20 2008-12-24 Vitae Pharmaceuticals, Inc. Renin inhibitors
BRPI0907612A2 (pt) 2008-01-08 2015-07-21 Lantheus Medical Imaging Inc Conjugados de n-coxiamida como agentes de imageamento
US8877157B2 (en) 2009-07-08 2014-11-04 Lantheus Medical Imaging, Inc. N-alkoxyamide conjugates as imaging agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4077998A (en) * 1975-10-28 1978-03-07 Morton-Norwich Products, Inc. Phthaloyl amino acid hydroxamic acids
US4687841A (en) * 1985-10-18 1987-08-18 Monsanto Company Peptide hydroxamic acid derivatives

Also Published As

Publication number Publication date
AU3265589A (en) 1989-10-19
JPH026452A (ja) 1990-01-10
NO177851B (no) 1995-08-28
DD294014A5 (de) 1991-09-19
IN169836B (it) 1991-12-28
IN172059B (it) 1993-03-27
BG88028A (bg) 1993-12-24
EP0337348B1 (en) 1994-02-02
NO891484D0 (no) 1989-04-11
IL89895A0 (en) 1989-12-15
FI891712A0 (fi) 1989-04-11
DE68912811D1 (de) 1994-03-17
IT8820172A0 (it) 1988-04-12
KR900016097A (ko) 1990-11-12
ATE101126T1 (de) 1994-02-15
CA1314903C (en) 1993-03-23
BG60556B1 (bg) 1995-08-28
UA15920A (uk) 1997-06-30
PL159413B1 (pl) 1992-12-31
RU2004538C1 (ru) 1993-12-15
MX15635A (es) 1993-12-01
AU611796B2 (en) 1991-06-20
PT90254A (pt) 1989-11-10
RO104347B1 (en) 1993-04-15
EP0337348A2 (en) 1989-10-18
ES2061759T3 (es) 1994-12-16
HUT50105A (en) 1989-12-28
IT1224627B (it) 1990-10-04
RU1838294C (ru) 1993-08-30
ZA892674B (en) 1989-12-27
HU206194B (en) 1992-09-28
PL278804A1 (en) 1990-01-08
DK173689D0 (da) 1989-04-11
NO891484L (no) 1989-10-13
YU73889A (en) 1991-04-30
EP0337348A3 (en) 1990-05-30
FI891712A (fi) 1989-10-13
US5095137A (en) 1992-03-10
DE68912811T2 (de) 1994-06-16
NZ228688A (en) 1992-03-26
DK173689A (da) 1989-10-13
PT90254B (pt) 1994-07-29
CN1037344A (zh) 1989-11-22

Similar Documents

Publication Publication Date Title
FI903879A0 (fi) Menetelmä valmistaa farmakologisesti käyttökelpoista tiatsoliyhdistettä
SG15689G (en) Substituted acyl derivatives of 1,2,3,4-tetrahydroiso-quinoline-3-carboxylic acids,salts thereof,pharmaceutical compositions containing the derivatives or salts,and the production of the same
NO174044C (no) Analogifremgangsmåte for fremstilling av et terapeutisk aktivt amid-derivat
CZ284872B6 (cs) Cyklické močoviny a jejich analogy a farmaceutické přípravky na jejich bázi
NO177851C (no) Analogifremgangsmåte for fremstilling av cyklometylen-1,2-bikarboksylsyreamider med terapeutisk aktivitet
NO176051C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-piperazinylbenzazol-derivater
DK562488D0 (da) Farmaceutisk praeparat indeholdende polyminderivater, samt nogle af disse polyaminderivater
GR871549B (en) Amino acid derivative anticonvulsant
FI893682A (fi) Menetelmä terapeuttisesti käyttökelpoisten 1,2,5-ditiatsosiinijohdannaisten valmistamiseksi
ATE104678T1 (de) Renin-hemmende aminodiol-derivate.
DE69014261D1 (de) N-Azabicyclo[3.3.0]octanamide von aromatischen Säuren.
HUT44268A (en) Process for preparing compounds with construction similar to antibiotic tan-749
ATE92461T1 (de) Gegen die zerebrale insuffizienz wirksame verbindungen.