DE69014261D1 - N-Azabicyclo[3.3.0]octanamide von aromatischen Säuren. - Google Patents

N-Azabicyclo[3.3.0]octanamide von aromatischen Säuren.

Info

Publication number
DE69014261D1
DE69014261D1 DE69014261T DE69014261T DE69014261D1 DE 69014261 D1 DE69014261 D1 DE 69014261D1 DE 69014261 T DE69014261 T DE 69014261T DE 69014261 T DE69014261 T DE 69014261T DE 69014261 D1 DE69014261 D1 DE 69014261D1
Authority
DE
Germany
Prior art keywords
octanamides
azabicyclo
aromatic acids
compound
antagonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69014261T
Other languages
English (en)
Other versions
DE69014261T2 (de
Inventor
Daniel Lamar Zabrowski
Daniel Lee Flynn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE69014261D1 publication Critical patent/DE69014261D1/de
Publication of DE69014261T2 publication Critical patent/DE69014261T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69014261T 1989-09-11 1990-09-11 N-Azabicyclo[3.3.0]octanamide von aromatischen Säuren. Expired - Fee Related DE69014261T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/406,205 US4992461A (en) 1989-09-11 1989-09-11 N-azabicyclo(3.3.0)octane amides of aromatic acids, compositions, and methods of use thereof

Publications (2)

Publication Number Publication Date
DE69014261D1 true DE69014261D1 (de) 1995-01-05
DE69014261T2 DE69014261T2 (de) 1995-05-04

Family

ID=23606972

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69014261T Expired - Fee Related DE69014261T2 (de) 1989-09-11 1990-09-11 N-Azabicyclo[3.3.0]octanamide von aromatischen Säuren.

Country Status (16)

Country Link
US (1) US4992461A (de)
EP (1) EP0417746B1 (de)
JP (1) JPH03167189A (de)
KR (1) KR910006292A (de)
AT (1) ATE114309T1 (de)
AU (1) AU6231090A (de)
CA (1) CA2024964C (de)
DE (1) DE69014261T2 (de)
DK (1) DK0417746T3 (de)
ES (1) ES2064577T3 (de)
FI (1) FI904449A0 (de)
IE (1) IE903283A1 (de)
IL (1) IL95619A0 (de)
NO (1) NO903927L (de)
PT (1) PT95254A (de)
ZA (1) ZA907213B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4104870A1 (de) * 1991-02-17 1992-08-27 Bayer Ag Verwendung von 3,(4)-substituierten pyrrolidinen als katalysatoren fuer das polyisocyanatpolyadditionsverfahren, verfahren zu ihrer herstellung sowie verfahren zur herstellung von polyurethan(harnstoff)en
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
US5840903A (en) * 1992-07-27 1998-11-24 G. D. Searle & Co. 4-aminomethyl-1-azaadamantane derived benzamides
US5354757A (en) * 1992-12-15 1994-10-11 G. D. Searle & Co. Azanoradamantanes
JP2999669B2 (ja) * 1993-08-24 2000-01-17 株式会社三和化学研究所 ベンゾ［ｂ］フランカルボキサミド誘導体、その製法及び用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593146A (en) * 1976-11-05 1981-07-15 Beecham Group Ltd Octahydro-quinolizinyl benzamide derivatives
US4409225A (en) * 1981-03-16 1983-10-11 Beecham Group Limited Substituted benzamides
JPS5946281A (ja) * 1982-09-09 1984-03-15 Suntory Ltd １置換ピロリチジン誘導体およびその用途
DE3687080T2 (de) * 1985-04-27 1993-03-25 Beecham Group Plc Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung.

Also Published As

Publication number Publication date
ATE114309T1 (de) 1994-12-15
EP0417746B1 (de) 1994-11-23
CA2024964A1 (en) 1991-03-12
JPH03167189A (ja) 1991-07-19
FI904449A0 (fi) 1990-09-10
IL95619A0 (en) 1991-06-30
NO903927L (no) 1991-03-12
KR910006292A (ko) 1991-04-29
PT95254A (pt) 1991-07-05
IE903283A1 (en) 1991-04-10
ES2064577T3 (es) 1995-02-01
DE69014261T2 (de) 1995-05-04
EP0417746A2 (de) 1991-03-20
AU6231090A (en) 1991-03-14
CA2024964C (en) 2000-03-28
DK0417746T3 (da) 1994-12-12
US4992461A (en) 1991-02-12
EP0417746A3 (en) 1991-11-06
ZA907213B (en) 1991-11-27
NO903927D0 (no) 1990-09-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee