ATE114309T1 - N-azabicyclo(3.3.0>octanamide von aromatischen säuren. - Google Patents

N-azabicyclo(3.3.0>octanamide von aromatischen säuren.

Info

Publication number
ATE114309T1
ATE114309T1 AT90117521T AT90117521T ATE114309T1 AT E114309 T1 ATE114309 T1 AT E114309T1 AT 90117521 T AT90117521 T AT 90117521T AT 90117521 T AT90117521 T AT 90117521T AT E114309 T1 ATE114309 T1 AT E114309T1
Authority
AT
Austria
Prior art keywords
octanamides
azabicyclo
aromatic acids
compound
antagonist
Prior art date
Application number
AT90117521T
Other languages
English (en)
Inventor
Daniel Lamar Zabrowski
Daniel Lee Flynn
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE114309T1 publication Critical patent/ATE114309T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT90117521T 1989-09-11 1990-09-11 N-azabicyclo(3.3.0>octanamide von aromatischen säuren. ATE114309T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/406,205 US4992461A (en) 1989-09-11 1989-09-11 N-azabicyclo(3.3.0)octane amides of aromatic acids, compositions, and methods of use thereof

Publications (1)

Publication Number Publication Date
ATE114309T1 true ATE114309T1 (de) 1994-12-15

Family

ID=23606972

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90117521T ATE114309T1 (de) 1989-09-11 1990-09-11 N-azabicyclo(3.3.0>octanamide von aromatischen säuren.

Country Status (16)

Country Link
US (1) US4992461A (de)
EP (1) EP0417746B1 (de)
JP (1) JPH03167189A (de)
KR (1) KR910006292A (de)
AT (1) ATE114309T1 (de)
AU (1) AU6231090A (de)
CA (1) CA2024964C (de)
DE (1) DE69014261T2 (de)
DK (1) DK0417746T3 (de)
ES (1) ES2064577T3 (de)
FI (1) FI904449A7 (de)
IE (1) IE903283A1 (de)
IL (1) IL95619A0 (de)
NO (1) NO903927L (de)
PT (1) PT95254A (de)
ZA (1) ZA907213B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4104870A1 (de) * 1991-02-17 1992-08-27 Bayer Ag Verwendung von 3,(4)-substituierten pyrrolidinen als katalysatoren fuer das polyisocyanatpolyadditionsverfahren, verfahren zu ihrer herstellung sowie verfahren zur herstellung von polyurethan(harnstoff)en
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
US5840903A (en) * 1992-07-27 1998-11-24 G. D. Searle & Co. 4-aminomethyl-1-azaadamantane derived benzamides
US5354757A (en) * 1992-12-15 1994-10-11 G. D. Searle & Co. Azanoradamantanes
JP2999669B2 (ja) * 1993-08-24 2000-01-17 株式会社三和化学研究所 ベンゾ［ｂ］フランカルボキサミド誘導体、その製法及び用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593146A (en) * 1976-11-05 1981-07-15 Beecham Group Ltd Octahydro-quinolizinyl benzamide derivatives
US4409225A (en) * 1981-03-16 1983-10-11 Beecham Group Limited Substituted benzamides
JPS5946281A (ja) * 1982-09-09 1984-03-15 Suntory Ltd １置換ピロリチジン誘導体およびその用途
DE3687080T2 (de) * 1985-04-27 1993-03-25 Beecham Group Plc Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung.

Also Published As

Publication number Publication date
IL95619A0 (en) 1991-06-30
IE903283A1 (en) 1991-04-10
AU6231090A (en) 1991-03-14
CA2024964A1 (en) 1991-03-12
DE69014261D1 (de) 1995-01-05
EP0417746A2 (de) 1991-03-20
CA2024964C (en) 2000-03-28
EP0417746A3 (en) 1991-11-06
NO903927L (no) 1991-03-12
EP0417746B1 (de) 1994-11-23
US4992461A (en) 1991-02-12
DE69014261T2 (de) 1995-05-04
NO903927D0 (no) 1990-09-10
KR910006292A (ko) 1991-04-29
ES2064577T3 (es) 1995-02-01
FI904449A7 (fi) 1991-03-12
JPH03167189A (ja) 1991-07-19
ZA907213B (en) 1991-11-27
FI904449A0 (fi) 1990-09-10
PT95254A (pt) 1991-07-05
DK0417746T3 (da) 1994-12-12

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee