DE68913099T2 - Amino-substituierte verbrückte azabicyclische Chinoloncarbonsäure und Ester. - Google Patents

Amino-substituierte verbrückte azabicyclische Chinoloncarbonsäure und Ester.

Info

Publication number
DE68913099T2
DE68913099T2 DE68913099T DE68913099T DE68913099T2 DE 68913099 T2 DE68913099 T2 DE 68913099T2 DE 68913099 T DE68913099 T DE 68913099T DE 68913099 T DE68913099 T DE 68913099T DE 68913099 T2 DE68913099 T2 DE 68913099T2
Authority
DE
Germany
Prior art keywords
ester
amino substituted
substituted bridged
quinolonecarboxylic acid
bridged azabicyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68913099T
Other languages
English (en)
Other versions
DE68913099D1 (de
Inventor
Edward Fox Kleinman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE68913099D1 publication Critical patent/DE68913099D1/de
Application granted granted Critical
Publication of DE68913099T2 publication Critical patent/DE68913099T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Catalysts (AREA)
DE68913099T 1988-08-23 1989-08-22 Amino-substituierte verbrückte azabicyclische Chinoloncarbonsäure und Ester. Expired - Fee Related DE68913099T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1988/002908 WO1990002123A1 (en) 1988-08-23 1988-08-23 Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters

Publications (2)

Publication Number Publication Date
DE68913099D1 DE68913099D1 (de) 1994-03-24
DE68913099T2 true DE68913099T2 (de) 1994-05-26

Family

ID=22208868

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68913099T Expired - Fee Related DE68913099T2 (de) 1988-08-23 1989-08-22 Amino-substituierte verbrückte azabicyclische Chinoloncarbonsäure und Ester.

Country Status (18)

Country Link
EP (1) EP0356193B1 (de)
JP (1) JPH0637495B2 (de)
KR (1) KR910007238B1 (de)
AT (1) ATE101609T1 (de)
AU (1) AU605434B2 (de)
CA (1) CA1334413C (de)
DE (1) DE68913099T2 (de)
DK (1) DK411989A (de)
ES (1) ES2062017T3 (de)
FI (1) FI97386C (de)
IE (1) IE61370B1 (de)
IL (1) IL91331A0 (de)
MY (1) MY107389A (de)
NO (1) NO901764L (de)
NZ (1) NZ230374A (de)
PT (1) PT91498B (de)
WO (1) WO1990002123A1 (de)
ZA (1) ZA896395B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04315332A (ja) * 1991-04-15 1992-11-06 Hitachi Ltd 誤り訂正装置
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
IN166416B (de) * 1985-09-18 1990-05-05 Pfizer
JPH089597B2 (ja) * 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
US4803205A (en) * 1987-08-07 1989-02-07 Warner-Lambert Company Quinolones as antibacterial agents

Also Published As

Publication number Publication date
EP0356193A3 (en) 1990-12-27
FI901994A0 (fi) 1990-04-20
CA1334413C (en) 1995-02-14
IE892683L (en) 1990-02-23
IE61370B1 (en) 1994-11-02
EP0356193A2 (de) 1990-02-28
IL91331A0 (en) 1990-03-19
AU605434B2 (en) 1991-01-10
PT91498B (pt) 1995-05-04
EP0356193B1 (de) 1994-02-16
JPH0291072A (ja) 1990-03-30
NZ230374A (en) 1991-07-26
DK411989D0 (da) 1989-08-22
ZA896395B (en) 1991-04-24
AU4011489A (en) 1990-05-03
MY107389A (en) 1995-11-30
NO901764D0 (no) 1990-04-20
DE68913099D1 (de) 1994-03-24
NO901764L (no) 1990-06-08
JPH0637495B2 (ja) 1994-05-18
ES2062017T3 (es) 1994-12-16
FI97386C (fi) 1996-12-10
WO1990002123A1 (en) 1990-03-08
FI97386B (fi) 1996-08-30
DK411989A (da) 1990-02-24
KR910007238B1 (ko) 1991-09-24
KR900003128A (ko) 1990-03-23
PT91498A (pt) 1990-03-08
ATE101609T1 (de) 1994-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee