ES2062017T3 - Acidos y esteres quinolon-carboxilicos amino-sustituidos y azabiciclo puenteados. - Google Patents
Acidos y esteres quinolon-carboxilicos amino-sustituidos y azabiciclo puenteados.Info
- Publication number
- ES2062017T3 ES2062017T3 ES89308478T ES89308478T ES2062017T3 ES 2062017 T3 ES2062017 T3 ES 2062017T3 ES 89308478 T ES89308478 T ES 89308478T ES 89308478 T ES89308478 T ES 89308478T ES 2062017 T3 ES2062017 T3 ES 2062017T3
- Authority
- ES
- Spain
- Prior art keywords
- azabiciclo
- quinolon
- bridged
- esters
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Catalysts (AREA)
Abstract
COMPUESTOS DE FORMULA (I), DONDE R1 ES H, ALQUILO C1-C6 O UN CATION FARMACEUTICAMENTE ACEPTABLE; Y ES CICLOPROPILO, ETILO O P-FLUOROFENILO; Y X ES H O FLUOR; O X E Y JUNTOS FORMAN UN GRUPO DE FORMULA: (FIG. A) O (FIG. B); Y R2 ES UN GRUPO DE FORMULA: (FIG. C), DONDE R3 ES H O ALQUILO C1-C4; O UNA DE SUS SALES FARMACEUTICAMENTE ACEPTABLES, TIENEN PROPIEDADES ANTIBACTERIANAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1988/002908 WO1990002123A1 (en) | 1988-08-23 | 1988-08-23 | Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2062017T3 true ES2062017T3 (es) | 1994-12-16 |
Family
ID=22208868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89308478T Expired - Lifetime ES2062017T3 (es) | 1988-08-23 | 1989-08-22 | Acidos y esteres quinolon-carboxilicos amino-sustituidos y azabiciclo puenteados. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0356193B1 (es) |
JP (1) | JPH0637495B2 (es) |
KR (1) | KR910007238B1 (es) |
AT (1) | ATE101609T1 (es) |
AU (1) | AU605434B2 (es) |
CA (1) | CA1334413C (es) |
DE (1) | DE68913099T2 (es) |
DK (1) | DK411989A (es) |
ES (1) | ES2062017T3 (es) |
FI (1) | FI97386C (es) |
IE (1) | IE61370B1 (es) |
IL (1) | IL91331A0 (es) |
MY (1) | MY107389A (es) |
NO (1) | NO901764L (es) |
NZ (1) | NZ230374A (es) |
PT (1) | PT91498B (es) |
WO (1) | WO1990002123A1 (es) |
ZA (1) | ZA896395B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04315332A (ja) * | 1991-04-15 | 1992-11-06 | Hitachi Ltd | 誤り訂正装置 |
US5527910A (en) * | 1992-12-30 | 1996-06-18 | Cheil Foods & Chemicals, Inc. | Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3227055A1 (de) * | 1982-07-20 | 1984-01-26 | Hoechst Ag, 6230 Frankfurt | Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung |
IE55898B1 (en) * | 1982-09-09 | 1991-02-14 | Warner Lambert Co | Antibacterial agents |
US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
IE58742B1 (en) * | 1984-07-20 | 1993-11-05 | Warner Lambert Co | Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds |
IN166416B (es) * | 1985-09-18 | 1990-05-05 | Pfizer | |
JPH089597B2 (ja) * | 1986-01-21 | 1996-01-31 | 杏林製薬株式会社 | 選択毒性に優れた8‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法 |
US4803205A (en) * | 1987-08-07 | 1989-02-07 | Warner-Lambert Company | Quinolones as antibacterial agents |
-
1988
- 1988-08-23 WO PCT/US1988/002908 patent/WO1990002123A1/en active IP Right Grant
-
1989
- 1989-08-16 IL IL91331A patent/IL91331A0/xx not_active IP Right Cessation
- 1989-08-21 PT PT91498A patent/PT91498B/pt not_active IP Right Cessation
- 1989-08-21 MY MYPI89001136A patent/MY107389A/en unknown
- 1989-08-21 CA CA000608920A patent/CA1334413C/en not_active Expired - Fee Related
- 1989-08-21 JP JP1214760A patent/JPH0637495B2/ja not_active Expired - Lifetime
- 1989-08-21 NZ NZ230374A patent/NZ230374A/en unknown
- 1989-08-22 AT AT89308478T patent/ATE101609T1/de not_active IP Right Cessation
- 1989-08-22 DK DK411989A patent/DK411989A/da not_active Application Discontinuation
- 1989-08-22 DE DE68913099T patent/DE68913099T2/de not_active Expired - Fee Related
- 1989-08-22 EP EP89308478A patent/EP0356193B1/en not_active Expired - Lifetime
- 1989-08-22 ES ES89308478T patent/ES2062017T3/es not_active Expired - Lifetime
- 1989-08-22 AU AU40114/89A patent/AU605434B2/en not_active Ceased
- 1989-08-22 KR KR1019890011932A patent/KR910007238B1/ko not_active IP Right Cessation
- 1989-08-22 IE IE268389A patent/IE61370B1/en not_active IP Right Cessation
- 1989-08-22 ZA ZA896395A patent/ZA896395B/xx unknown
-
1990
- 1990-04-20 FI FI901994A patent/FI97386C/fi not_active IP Right Cessation
- 1990-04-20 NO NO90901764A patent/NO901764L/no unknown
Also Published As
Publication number | Publication date |
---|---|
CA1334413C (en) | 1995-02-14 |
NZ230374A (en) | 1991-07-26 |
AU605434B2 (en) | 1991-01-10 |
ZA896395B (en) | 1991-04-24 |
EP0356193B1 (en) | 1994-02-16 |
EP0356193A3 (en) | 1990-12-27 |
IE892683L (en) | 1990-02-23 |
PT91498A (pt) | 1990-03-08 |
AU4011489A (en) | 1990-05-03 |
KR900003128A (ko) | 1990-03-23 |
IE61370B1 (en) | 1994-11-02 |
DE68913099D1 (de) | 1994-03-24 |
FI901994A0 (fi) | 1990-04-20 |
FI97386B (fi) | 1996-08-30 |
EP0356193A2 (en) | 1990-02-28 |
ATE101609T1 (de) | 1994-03-15 |
NO901764L (no) | 1990-06-08 |
PT91498B (pt) | 1995-05-04 |
FI97386C (fi) | 1996-12-10 |
DK411989A (da) | 1990-02-24 |
WO1990002123A1 (en) | 1990-03-08 |
DK411989D0 (da) | 1989-08-22 |
DE68913099T2 (de) | 1994-05-26 |
KR910007238B1 (ko) | 1991-09-24 |
JPH0291072A (ja) | 1990-03-30 |
MY107389A (en) | 1995-11-30 |
IL91331A0 (en) | 1990-03-19 |
NO901764D0 (no) | 1990-04-20 |
JPH0637495B2 (ja) | 1994-05-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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