NO175747C - Analogifremgangsmåte for fremstilling av 4-(5,6,7,8-tetra-hydroimidazol(1,5-a)pyrimidin-5-yl)-benzonitril-hydroklorid - Google Patents
Analogifremgangsmåte for fremstilling av 4-(5,6,7,8-tetra-hydroimidazol(1,5-a)pyrimidin-5-yl)-benzonitril-hydrokloridInfo
- Publication number
- NO175747C NO175747C NO910137A NO910137A NO175747C NO 175747 C NO175747 C NO 175747C NO 910137 A NO910137 A NO 910137A NO 910137 A NO910137 A NO 910137A NO 175747 C NO175747 C NO 175747C
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- tetrahydroimidazole
- pyrimidin
- benzonitrile hydrochloride
- analogous process
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title abstract 2
- JFDZBHWFFUWGJE-UHFFFAOYSA-N benzonitrile Substances N#CC1=CC=CC=C1 JFDZBHWFFUWGJE-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 title 1
- 125000004938 5-pyridyl group Chemical group N1=CC=CC(=C1)* 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Lubricants (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Liquid Crystal Substances (AREA)
- Pyridine Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH10090 | 1990-01-12 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO910137D0 NO910137D0 (no) | 1991-01-11 |
| NO910137L NO910137L (no) | 1991-07-15 |
| NO175747B NO175747B (no) | 1994-08-22 |
| NO175747C true NO175747C (no) | 1994-11-30 |
Family
ID=4179261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO910137A NO175747C (no) | 1990-01-12 | 1991-01-11 | Analogifremgangsmåte for fremstilling av 4-(5,6,7,8-tetra-hydroimidazol(1,5-a)pyrimidin-5-yl)-benzonitril-hydroklorid |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US5098911A (ro) |
| EP (1) | EP0437415B1 (ro) |
| JP (1) | JP2694186B2 (ro) |
| KR (1) | KR100191360B1 (ro) |
| CN (1) | CN1037966C (ro) |
| AT (1) | ATE125809T1 (ro) |
| AU (1) | AU638085B2 (ro) |
| BG (2) | BG60033A3 (ro) |
| CA (1) | CA2033937C (ro) |
| CZ (1) | CZ279823B6 (ro) |
| DE (1) | DE59106101D1 (ro) |
| DK (1) | DK0437415T3 (ro) |
| DZ (1) | DZ1482A1 (ro) |
| ES (1) | ES2075399T3 (ro) |
| FI (1) | FI94528C (ro) |
| GR (1) | GR3017027T3 (ro) |
| HK (1) | HK1000663A1 (ro) |
| HU (1) | HU216192B (ro) |
| ID (1) | ID964B (ro) |
| IE (1) | IE67512B1 (ro) |
| IL (1) | IL96879A (ro) |
| MA (1) | MA22040A1 (ro) |
| MT (1) | MTP1076B (ro) |
| NO (1) | NO175747C (ro) |
| NZ (1) | NZ236735A (ro) |
| PH (1) | PH27601A (ro) |
| PL (3) | PL166500B1 (ro) |
| PT (1) | PT96447B (ro) |
| RO (1) | RO107408B1 (ro) |
| RU (2) | RU2021271C1 (ro) |
| SA (1) | SA93140021B1 (ro) |
| TN (1) | TNSN91001A1 (ro) |
| ZA (1) | ZA91229B (ro) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW208013B (ro) * | 1990-03-01 | 1993-06-21 | Daiichi Co Ltd | |
| EP0457716A1 (de) * | 1990-04-20 | 1991-11-21 | Ciba-Geigy Ag | Naphthalinderivate |
| TW224461B (ro) * | 1990-09-18 | 1994-06-01 | Ciba Geigy Ag | |
| CH683151A5 (de) * | 1991-04-24 | 1994-01-31 | Ciba Geigy Ag | Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus. |
| JP2914324B2 (ja) * | 1995-10-23 | 1999-06-28 | 味の素株式会社 | ピペリジン誘導体の結晶並びにその製造中間体及び製造方法 |
| KR101913442B1 (ko) | 2010-09-01 | 2018-10-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 체중 관리에 유용한 5-ｈｔ2ｃ 작동제의 변형-방출 투여 형태 |
| WO2012030939A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Administration of lorcaserin to individuals with renal impairment |
| AP2014007762A0 (en) | 2012-01-17 | 2014-07-31 | Novartis Ag | New forms and salts of a dihydropyrrolo[1,2C]imidazolyl aldosterone synthase or aromatase inhibitor |
| WO2018078049A1 (en) | 2016-10-27 | 2018-05-03 | Damian Pharma Ag | Aldosterone synthase inhibitor |
| CN114853755A (zh) | 2016-10-27 | 2022-08-05 | 达米安制药股份公司 | 醛固酮合酶抑制剂 |
| BR112020022173A2 (pt) | 2018-05-03 | 2021-02-02 | Damian Pharma Ag | r-fadrozol para uso no tratamento de aldostonerismo |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617307A (en) * | 1984-06-20 | 1986-10-14 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors |
| US4588732A (en) * | 1982-12-21 | 1986-05-13 | Ciba-Geigy Corporation | Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors |
-
1990
- 1990-12-14 MT MT1076A patent/MTP1076B/xx unknown
-
1991
- 1991-01-02 US US07/636,816 patent/US5098911A/en not_active Expired - Lifetime
- 1991-01-02 PH PH41805A patent/PH27601A/en unknown
- 1991-01-03 DE DE59106101T patent/DE59106101D1/de not_active Expired - Lifetime
- 1991-01-03 DK DK91810003.3T patent/DK0437415T3/da active
- 1991-01-03 EP EP91810003A patent/EP0437415B1/de not_active Expired - Lifetime
- 1991-01-03 ES ES91810003T patent/ES2075399T3/es not_active Expired - Lifetime
- 1991-01-03 AT AT91810003T patent/ATE125809T1/de not_active IP Right Cessation
- 1991-01-04 IL IL9687991A patent/IL96879A/en not_active IP Right Cessation
- 1991-01-07 MA MA22312A patent/MA22040A1/fr unknown
- 1991-01-09 FI FI910126A patent/FI94528C/fi active
- 1991-01-09 DZ DZ910008A patent/DZ1482A1/fr active
- 1991-01-10 KR KR1019910000244A patent/KR100191360B1/ko not_active IP Right Cessation
- 1991-01-10 NZ NZ236735A patent/NZ236735A/xx unknown
- 1991-01-10 PL PL91304087A patent/PL166500B1/pl unknown
- 1991-01-10 PL PL91288653A patent/PL166157B1/pl unknown
- 1991-01-10 RO RO146713A patent/RO107408B1/ro unknown
- 1991-01-10 PT PT96447A patent/PT96447B/pt not_active IP Right Cessation
- 1991-01-10 CA CA002033937A patent/CA2033937C/en not_active Expired - Lifetime
- 1991-01-10 AU AU69280/91A patent/AU638085B2/en not_active Expired
- 1991-01-10 PL PL91304084A patent/PL167164B1/pl unknown
- 1991-01-11 TN TNTNSN91001A patent/TNSN91001A1/fr unknown
- 1991-01-11 ZA ZA91229A patent/ZA91229B/xx unknown
- 1991-01-11 RU SU914894233A patent/RU2021271C1/ru active
- 1991-01-11 CZ CS9155A patent/CZ279823B6/cs not_active IP Right Cessation
- 1991-01-11 NO NO910137A patent/NO175747C/no not_active IP Right Cessation
- 1991-01-11 HU HU4/91A patent/HU216192B/hu unknown
- 1991-01-11 CN CN91101118A patent/CN1037966C/zh not_active Expired - Lifetime
- 1991-01-11 IE IE10391A patent/IE67512B1/en not_active IP Right Cessation
- 1991-01-11 JP JP3065711A patent/JP2694186B2/ja not_active Expired - Lifetime
- 1991-01-14 BG BG93623A patent/BG60033A3/xx unknown
-
1992
- 1992-01-30 ID IDP190792A patent/ID964B/id unknown
- 1992-04-07 RU SU925011257A patent/RU2088584C1/ru active
- 1992-08-18 BG BG96793A patent/BG61489B2/bg unknown
-
1993
- 1993-06-29 SA SA93140021A patent/SA93140021B1/ar unknown
-
1995
- 1995-08-03 GR GR950401945T patent/GR3017027T3/el unknown
-
1997
- 1997-11-24 HK HK97102235A patent/HK1000663A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |