NO171505C - Fremgangsmaate for syntese av amikacin - Google Patents

Fremgangsmaate for syntese av amikacin

Info

Publication number
NO171505C
NO171505C NO885270A NO885270A NO171505C NO 171505 C NO171505 C NO 171505C NO 885270 A NO885270 A NO 885270A NO 885270 A NO885270 A NO 885270A NO 171505 C NO171505 C NO 171505C
Authority
NO
Norway
Prior art keywords
synthesis
amikacin
procedure
derivative
economicity
Prior art date
Application number
NO885270A
Other languages
English (en)
Other versions
NO885270D0 (no
NO885270L (no
NO171505B (no
Inventor
Alberto Mangia
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of NO885270D0 publication Critical patent/NO885270D0/no
Publication of NO885270L publication Critical patent/NO885270L/no
Publication of NO171505B publication Critical patent/NO171505B/no
Publication of NO171505C publication Critical patent/NO171505C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Insulating Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Polymerisation Methods In General (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
NO885270A 1987-11-27 1988-11-25 Fremgangsmaate for syntese av amikacin NO171505C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8722783A IT1225484B (it) 1987-11-27 1987-11-27 Procedimento di sintesi dell'amikacina

Publications (4)

Publication Number Publication Date
NO885270D0 NO885270D0 (no) 1988-11-25
NO885270L NO885270L (no) 1989-05-29
NO171505B NO171505B (no) 1992-12-14
NO171505C true NO171505C (no) 1993-03-24

Family

ID=11200418

Family Applications (1)

Application Number Title Priority Date Filing Date
NO885270A NO171505C (no) 1987-11-27 1988-11-25 Fremgangsmaate for syntese av amikacin

Country Status (23)

Country Link
US (1) US5763587A (no)
EP (1) EP0317970B1 (no)
JP (1) JPH0637512B2 (no)
AT (1) ATE125544T1 (no)
AU (1) AU608665B2 (no)
BG (1) BG49048A3 (no)
CA (1) CA1324375C (no)
CS (1) CS277017B6 (no)
DD (1) DD283564A5 (no)
DE (1) DE3854225T2 (no)
DK (1) DK170050B1 (no)
ES (1) ES2074431T3 (no)
FI (1) FI90243C (no)
HU (1) HU201771B (no)
IT (1) IT1225484B (no)
NO (1) NO171505C (no)
NZ (1) NZ227113A (no)
PH (1) PH25818A (no)
PL (1) PL161416B1 (no)
RO (1) RO102339B1 (no)
RU (1) RU1776262C (no)
YU (1) YU47063B (no)
ZA (1) ZA888855B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW465235B (en) 1998-09-17 2001-11-21 United Video Properties Inc Electronic program guide with digital storage
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
KR101424518B1 (ko) * 2005-09-29 2014-08-06 노바르티스 아게 항생제 제형, 단위 투여체, 키트 및 방법
EP1957507B1 (en) 2005-12-02 2018-10-24 Ionis Pharmaceuticals, Inc. Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
JP2010527913A (ja) * 2007-04-10 2010-08-19 アカオジェン インコーポレイテッド 抗菌性１，４，５置換アミノグリコシド類似体
WO2010030690A1 (en) * 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
US8791245B2 (en) * 2008-10-03 2014-07-29 Glycan Bioscience LLC Anionic conjugates of glycosylated bacterial metabolite
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
CN102596981A (zh) 2009-10-09 2012-07-18 尔察祯有限公司 抗菌氨基糖苷类类似物
WO2012067978A1 (en) 2010-11-17 2012-05-24 Achaogen, Inc. Antibacterial amiinoglycoside analogs
CN103113429B (zh) * 2013-03-05 2015-02-18 齐鲁天和惠世制药有限公司 一种由阿米卡星制备硫酸阿米卡星的方法
CN105440090B (zh) * 2014-08-27 2018-03-09 北大医药重庆大新药业股份有限公司 一种阿米卡星的合成方法
CN111233952A (zh) * 2020-04-02 2020-06-05 管炫棣 一种阿卡米星的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60217C (fi) * 1973-11-14 1981-12-10 Bristol Myers Co Foerfarande foer framstaellning av 1-(l-(-)-ny-amino-alfa-hydroxibutyryl)kanamycin a
JPS51127045A (en) * 1975-04-24 1976-11-05 Microbial Chem Res Found A process for preparing 3'- deoxykanamycin a derivatives.
GB1530201A (en) * 1976-04-14 1978-10-25 Pfizer Ltd Process for the preparation of aminoglycoside antibiotics and intermediates therefor
US4136254A (en) * 1976-06-17 1979-01-23 Schering Corporation Process of selectively blocking amino functions in aminoglycosides using transition metal salts and intermediates used thereby
IE54288B1 (en) * 1982-03-05 1989-08-16 Fujisawa Pharmaceutical Co New 1,4-diaminocyclitol derivatives, processes for their preparation and pharmaceutical compositions containing them
JPS6041692A (ja) * 1983-08-15 1985-03-05 Microbial Chem Res Found ２′，３′−ジデオキシカナマイシンａ誘導体
IT1200774B (it) * 1985-10-10 1989-01-27 Pierrel Spa Procedimento di sentisi dell'amikacina

Also Published As

Publication number Publication date
PH25818A (en) 1991-11-05
CS777988A3 (en) 1992-06-17
NO885270D0 (no) 1988-11-25
AU2596388A (en) 1989-06-01
PL161416B1 (pl) 1993-06-30
IT8722783A0 (it) 1987-11-27
DD283564A5 (de) 1990-10-17
EP0317970A2 (en) 1989-05-31
NO885270L (no) 1989-05-29
NO171505B (no) 1992-12-14
BG49048A3 (en) 1991-07-15
DK170050B1 (da) 1995-05-08
CA1324375C (en) 1993-11-16
FI90243B (fi) 1993-09-30
YU47063B (sh) 1994-12-28
EP0317970B1 (en) 1995-07-26
DE3854225D1 (de) 1995-08-31
PL276047A1 (en) 1989-07-10
US5763587A (en) 1998-06-09
JPH01186900A (ja) 1989-07-26
FI90243C (fi) 1994-01-10
HU201771B (en) 1990-12-28
ES2074431T3 (es) 1995-09-16
FI885489A (fi) 1989-05-28
CS277017B6 (en) 1992-11-18
DK661588A (da) 1989-05-28
EP0317970A3 (en) 1991-08-28
ZA888855B (en) 1990-02-28
DK661588D0 (da) 1988-11-25
RO102339B1 (ro) 1992-08-01
AU608665B2 (en) 1991-04-11
RU1776262C (ru) 1992-11-15
YU218888A (en) 1989-12-31
NZ227113A (en) 1991-01-29
JPH0637512B2 (ja) 1994-05-18
HUT49144A (en) 1989-08-28
IT1225484B (it) 1990-11-14
FI885489A0 (fi) 1988-11-25
DE3854225T2 (de) 1996-01-04
ATE125544T1 (de) 1995-08-15

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