FI885489A0 - Menetelmä amikasiinin valmistamiseksi - Google Patents

Menetelmä amikasiinin valmistamiseksi

Info

Publication number
FI885489A0
FI885489A0 FI885489A FI885489A FI885489A0 FI 885489 A0 FI885489 A0 FI 885489A0 FI 885489 A FI885489 A FI 885489A FI 885489 A FI885489 A FI 885489A FI 885489 A0 FI885489 A0 FI 885489A0
Authority
FI
Finland
Prior art keywords
amikacin
preparation
synthesis
derivative
economicity
Prior art date
Application number
FI885489A
Other languages
English (en)
Swedish (sv)
Other versions
FI885489A (fi
FI90243B (fi
FI90243C (fi
Inventor
Alberto Mangia
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of FI885489A0 publication Critical patent/FI885489A0/fi
Publication of FI885489A publication Critical patent/FI885489A/fi
Publication of FI90243B publication Critical patent/FI90243B/fi
Application granted granted Critical
Publication of FI90243C publication Critical patent/FI90243C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Insulating Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polymerisation Methods In General (AREA)
  • Quinoline Compounds (AREA)
  • Steroid Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
FI885489A 1987-11-27 1988-11-25 Menetelmä amikasiinin valmistamiseksi FI90243C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8722783A IT1225484B (it) 1987-11-27 1987-11-27 Procedimento di sintesi dell'amikacina
IT2278387 1987-11-27

Publications (4)

Publication Number Publication Date
FI885489A0 true FI885489A0 (fi) 1988-11-25
FI885489A FI885489A (fi) 1989-05-28
FI90243B FI90243B (fi) 1993-09-30
FI90243C FI90243C (fi) 1994-01-10

Family

ID=11200418

Family Applications (1)

Application Number Title Priority Date Filing Date
FI885489A FI90243C (fi) 1987-11-27 1988-11-25 Menetelmä amikasiinin valmistamiseksi

Country Status (23)

Country Link
US (1) US5763587A (fi)
EP (1) EP0317970B1 (fi)
JP (1) JPH0637512B2 (fi)
AT (1) ATE125544T1 (fi)
AU (1) AU608665B2 (fi)
BG (1) BG49048A3 (fi)
CA (1) CA1324375C (fi)
CS (1) CS277017B6 (fi)
DD (1) DD283564A5 (fi)
DE (1) DE3854225T2 (fi)
DK (1) DK170050B1 (fi)
ES (1) ES2074431T3 (fi)
FI (1) FI90243C (fi)
HU (1) HU201771B (fi)
IT (1) IT1225484B (fi)
NO (1) NO171505C (fi)
NZ (1) NZ227113A (fi)
PH (1) PH25818A (fi)
PL (1) PL161416B1 (fi)
RO (1) RO102339B1 (fi)
RU (1) RU1776262C (fi)
YU (1) YU47063B (fi)
ZA (1) ZA888855B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW465235B (en) 1998-09-17 2001-11-21 United Video Properties Inc Electronic program guide with digital storage
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
JP2009510077A (ja) 2005-09-29 2009-03-12 ネクター セラピューティックス 抗生物質製剤、単位用量、キットおよび方法
CA2632968A1 (en) 2005-12-02 2007-06-07 Isis Pharmaceuticals, Inc. Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
US20080300199A1 (en) * 2007-04-10 2008-12-04 Achaogen Inc. Antibacterial 1,4,5-substituted aminoglycoside analogs
WO2010030690A1 (en) * 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
CN102256989B (zh) * 2008-10-03 2016-01-06 聚糖生物科学有限责任公司 糖基化细菌代谢物的阴离子轭合物
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
CN102596981A (zh) 2009-10-09 2012-07-18 尔察祯有限公司 抗菌氨基糖苷类类似物
CN103282370A (zh) 2010-11-17 2013-09-04 尔察祯有限公司 抗菌氨基糖苷类类似物
CN103113429B (zh) * 2013-03-05 2015-02-18 齐鲁天和惠世制药有限公司 一种由阿米卡星制备硫酸阿米卡星的方法
CN105440090B (zh) * 2014-08-27 2018-03-09 北大医药重庆大新药业股份有限公司 一种阿米卡星的合成方法
CN111233952A (zh) * 2020-04-02 2020-06-05 管炫棣 一种阿卡米星的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60217C (fi) * 1973-11-14 1981-12-10 Bristol Myers Co Foerfarande foer framstaellning av 1-(l-(-)-ny-amino-alfa-hydroxibutyryl)kanamycin a
JPS51127045A (en) * 1975-04-24 1976-11-05 Microbial Chem Res Found A process for preparing 3'- deoxykanamycin a derivatives.
GB1530201A (en) * 1976-04-14 1978-10-25 Pfizer Ltd Process for the preparation of aminoglycoside antibiotics and intermediates therefor
US4136254A (en) * 1976-06-17 1979-01-23 Schering Corporation Process of selectively blocking amino functions in aminoglycosides using transition metal salts and intermediates used thereby
IE54288B1 (en) * 1982-03-05 1989-08-16 Fujisawa Pharmaceutical Co New 1,4-diaminocyclitol derivatives, processes for their preparation and pharmaceutical compositions containing them
JPS6041692A (ja) * 1983-08-15 1985-03-05 Microbial Chem Res Found ２′，３′−ジデオキシカナマイシンａ誘導体
IT1200774B (it) * 1985-10-10 1989-01-27 Pierrel Spa Procedimento di sentisi dell'amikacina

Also Published As

Publication number Publication date
DE3854225T2 (de) 1996-01-04
DK661588D0 (da) 1988-11-25
NO885270L (no) 1989-05-29
CA1324375C (en) 1993-11-16
NZ227113A (en) 1991-01-29
CS777988A3 (en) 1992-06-17
NO171505C (no) 1993-03-24
ES2074431T3 (es) 1995-09-16
AU608665B2 (en) 1991-04-11
IT8722783A0 (it) 1987-11-27
BG49048A3 (en) 1991-07-15
CS277017B6 (en) 1992-11-18
HUT49144A (en) 1989-08-28
RU1776262C (ru) 1992-11-15
EP0317970A3 (en) 1991-08-28
JPH0637512B2 (ja) 1994-05-18
RO102339B1 (ro) 1992-08-01
FI885489A (fi) 1989-05-28
JPH01186900A (ja) 1989-07-26
PL161416B1 (pl) 1993-06-30
ATE125544T1 (de) 1995-08-15
FI90243B (fi) 1993-09-30
EP0317970A2 (en) 1989-05-31
PH25818A (en) 1991-11-05
DD283564A5 (de) 1990-10-17
NO885270D0 (no) 1988-11-25
YU47063B (sh) 1994-12-28
DK170050B1 (da) 1995-05-08
DK661588A (da) 1989-05-28
US5763587A (en) 1998-06-09
IT1225484B (it) 1990-11-14
EP0317970B1 (en) 1995-07-26
DE3854225D1 (de) 1995-08-31
YU218888A (en) 1989-12-31
PL276047A1 (en) 1989-07-10
HU201771B (en) 1990-12-28
ZA888855B (en) 1990-02-28
AU2596388A (en) 1989-06-01
FI90243C (fi) 1994-01-10
NO171505B (no) 1992-12-14

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: PIERREL S.P.A.