GB1420530A - Process for preparing quinoline derivatives - Google Patents

Process for preparing quinoline derivatives

Info

Publication number
GB1420530A
GB1420530A GB4001374A GB4001374A GB1420530A GB 1420530 A GB1420530 A GB 1420530A GB 4001374 A GB4001374 A GB 4001374A GB 4001374 A GB4001374 A GB 4001374A GB 1420530 A GB1420530 A GB 1420530A
Authority
GB
United Kingdom
Prior art keywords
acetoacetamidoquinoline
dihydro
oxo
methyl
quinoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4001374A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1349373A external-priority patent/CH577973A5/en
Priority claimed from CH1349273A external-priority patent/CH572471A5/en
Application filed by Lonza AG filed Critical Lonza AG
Publication of GB1420530A publication Critical patent/GB1420530A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

1420530 1,2 - Dihydro - 2 - oxo - 4 - methyl -7- acetoacetamidoquinoline LONZA Ltd 13 Sept 1974 [20 Sept 1973 (2)] 40013/74 Heading C2C The novel compound 1,2-dihydro-2-oxo-4- methyl-7-acetoacetamidoquinoline and the known compound 1,2-dihydro-2-oxo-4-methyl- 7-aminoquinoline are prepared by reacting diketene with phenylene-1,3-diamine in a mol. ratio of 1 : 1 to give the 7-aminoquinoline and a mol. ratio of 2 : 1 to give the 7-acetoacetamidoquinoline. The reaction is preferably carried out in water with the addition of acetic acid as a catalyst, and optionally an organic solvent at a temperature of below 100‹ C.
GB4001374A 1973-09-20 1974-09-13 Process for preparing quinoline derivatives Expired GB1420530A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1349373A CH577973A5 (en) 1973-09-20 1973-09-20 4-Methyl-7-substd.-2(1H)-quinolones prepn. - by reacting 1,3-phenylenediamine with diketene
CH1349273A CH572471A5 (en) 1973-09-20 1973-09-20 4-Methyl-7-substd.-2(1H)-quinolones prepn. - by reacting 1,3-phenylenediamine with diketene

Publications (1)

Publication Number Publication Date
GB1420530A true GB1420530A (en) 1976-01-07

Family

ID=25712387

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4001374A Expired GB1420530A (en) 1973-09-20 1974-09-13 Process for preparing quinoline derivatives

Country Status (11)

Country Link
JP (1) JPS5058080A (en)
AT (1) AT337184B (en)
CA (1) CA1042894A (en)
CS (1) CS182266B2 (en)
DD (1) DD113536A5 (en)
DE (1) DE2444519C2 (en)
FR (1) FR2244763B1 (en)
GB (1) GB1420530A (en)
IT (1) IT1035085B (en)
LU (1) LU70958A1 (en)
NL (1) NL7412463A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005518373A (en) * 2001-12-11 2005-06-23 チバ　スペシャルティ　ケミカルズ　ホールディング　インコーポレーテッド Process for producing 4-methyl-7-aminoquinolone

Also Published As

Publication number Publication date
DD113536A5 (en) 1975-06-12
CS182266B2 (en) 1978-04-28
DE2444519C2 (en) 1982-08-26
IT1035085B (en) 1979-10-20
NL7412463A (en) 1975-03-24
AT337184B (en) 1977-06-10
ATA759274A (en) 1976-10-15
LU70958A1 (en) 1975-05-28
CA1042894A (en) 1978-11-21
FR2244763A1 (en) 1975-04-18
JPS5058080A (en) 1975-05-20
DE2444519A1 (en) 1975-03-27
FR2244763B1 (en) 1979-03-16

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee