DK661588D0 - Fremgangsmaade til fremstilling af amikacin - Google Patents

Fremgangsmaade til fremstilling af amikacin

Info

Publication number
DK661588D0
DK661588D0 DK661588A DK661588A DK661588D0 DK 661588 D0 DK661588 D0 DK 661588D0 DK 661588 A DK661588 A DK 661588A DK 661588 A DK661588 A DK 661588A DK 661588 D0 DK661588 D0 DK 661588D0
Authority
DK
Denmark
Prior art keywords
amikacin
manufacturing
synthesis
derivative
economicity
Prior art date
Application number
DK661588A
Other languages
English (en)
Other versions
DK170050B1 (da
DK661588A (da
Inventor
Alberto Mangia
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of DK661588D0 publication Critical patent/DK661588D0/da
Publication of DK661588A publication Critical patent/DK661588A/da
Application granted granted Critical
Publication of DK170050B1 publication Critical patent/DK170050B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Insulating Materials (AREA)
  • Polymerisation Methods In General (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
DK661588A 1987-11-27 1988-11-25 Fremgangsmåde til fremstilling af amikacin DK170050B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8722783A IT1225484B (it) 1987-11-27 1987-11-27 Procedimento di sintesi dell'amikacina
IT2278387 1987-11-27

Publications (3)

Publication Number Publication Date
DK661588D0 true DK661588D0 (da) 1988-11-25
DK661588A DK661588A (da) 1989-05-28
DK170050B1 DK170050B1 (da) 1995-05-08

Family

ID=11200418

Family Applications (1)

Application Number Title Priority Date Filing Date
DK661588A DK170050B1 (da) 1987-11-27 1988-11-25 Fremgangsmåde til fremstilling af amikacin

Country Status (23)

Country Link
US (1) US5763587A (da)
EP (1) EP0317970B1 (da)
JP (1) JPH0637512B2 (da)
AT (1) ATE125544T1 (da)
AU (1) AU608665B2 (da)
BG (1) BG49048A3 (da)
CA (1) CA1324375C (da)
CS (1) CS277017B6 (da)
DD (1) DD283564A5 (da)
DE (1) DE3854225T2 (da)
DK (1) DK170050B1 (da)
ES (1) ES2074431T3 (da)
FI (1) FI90243C (da)
HU (1) HU201771B (da)
IT (1) IT1225484B (da)
NO (1) NO171505C (da)
NZ (1) NZ227113A (da)
PH (1) PH25818A (da)
PL (1) PL161416B1 (da)
RO (1) RO102339B1 (da)
RU (1) RU1776262C (da)
YU (1) YU47063B (da)
ZA (1) ZA888855B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW465235B (en) 1998-09-17 2001-11-21 United Video Properties Inc Electronic program guide with digital storage
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
BRPI0616642A2 (pt) 2005-09-29 2011-06-28 Nektar Therapeutics formulações de antibióticos, doses unitárias, kits e métodos
EP1957507B1 (en) 2005-12-02 2018-10-24 Ionis Pharmaceuticals, Inc. Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
CA2684957A1 (en) * 2007-04-10 2008-10-16 Achaogen Inc. Antibacterial 1,4,5-substituted aminoglycoside analogs
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010030690A1 (en) * 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010037179A1 (en) 2008-10-03 2010-04-08 Glycan Biosciences Pty Ltd Anionic conjugates of glycosylated bacterial metabolite
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
MX2012004036A (es) 2009-10-09 2012-06-27 Achaogen Inc Analogos de aminoglicosidos antibacterianos.
CN103282370A (zh) 2010-11-17 2013-09-04 尔察祯有限公司 抗菌氨基糖苷类类似物
CN103113429B (zh) * 2013-03-05 2015-02-18 齐鲁天和惠世制药有限公司 一种由阿米卡星制备硫酸阿米卡星的方法
CN105440090B (zh) * 2014-08-27 2018-03-09 北大医药重庆大新药业股份有限公司 一种阿米卡星的合成方法
CN111233952A (zh) * 2020-04-02 2020-06-05 管炫棣 一种阿卡米星的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI60217C (fi) * 1973-11-14 1981-12-10 Bristol Myers Co Foerfarande foer framstaellning av 1-(l-(-)-ny-amino-alfa-hydroxibutyryl)kanamycin a
JPS51127045A (en) * 1975-04-24 1976-11-05 Microbial Chem Res Found A process for preparing 3'- deoxykanamycin a derivatives.
GB1530201A (en) * 1976-04-14 1978-10-25 Pfizer Ltd Process for the preparation of aminoglycoside antibiotics and intermediates therefor
US4136254A (en) * 1976-06-17 1979-01-23 Schering Corporation Process of selectively blocking amino functions in aminoglycosides using transition metal salts and intermediates used thereby
IE54288B1 (en) * 1982-03-05 1989-08-16 Fujisawa Pharmaceutical Co New 1,4-diaminocyclitol derivatives, processes for their preparation and pharmaceutical compositions containing them
JPS6041692A (ja) * 1983-08-15 1985-03-05 Microbial Chem Res Found ２′，３′−ジデオキシカナマイシンａ誘導体
IT1200774B (it) * 1985-10-10 1989-01-27 Pierrel Spa Procedimento di sentisi dell'amikacina

Also Published As

Publication number Publication date
JPH01186900A (ja) 1989-07-26
AU608665B2 (en) 1991-04-11
PL276047A1 (en) 1989-07-10
RO102339B1 (ro) 1992-08-01
HU201771B (en) 1990-12-28
FI90243B (fi) 1993-09-30
DD283564A5 (de) 1990-10-17
ATE125544T1 (de) 1995-08-15
RU1776262C (ru) 1992-11-15
CS777988A3 (en) 1992-06-17
YU218888A (en) 1989-12-31
NZ227113A (en) 1991-01-29
US5763587A (en) 1998-06-09
CA1324375C (en) 1993-11-16
AU2596388A (en) 1989-06-01
NO885270L (no) 1989-05-29
CS277017B6 (en) 1992-11-18
ES2074431T3 (es) 1995-09-16
DK170050B1 (da) 1995-05-08
NO171505B (no) 1992-12-14
NO171505C (no) 1993-03-24
IT8722783A0 (it) 1987-11-27
IT1225484B (it) 1990-11-14
JPH0637512B2 (ja) 1994-05-18
NO885270D0 (no) 1988-11-25
YU47063B (sh) 1994-12-28
ZA888855B (en) 1990-02-28
DE3854225T2 (de) 1996-01-04
PL161416B1 (pl) 1993-06-30
EP0317970A3 (en) 1991-08-28
DE3854225D1 (de) 1995-08-31
BG49048A3 (en) 1991-07-15
DK661588A (da) 1989-05-28
FI885489A0 (fi) 1988-11-25
PH25818A (en) 1991-11-05
EP0317970A2 (en) 1989-05-31
EP0317970B1 (en) 1995-07-26
FI885489A (fi) 1989-05-28
HUT49144A (en) 1989-08-28
FI90243C (fi) 1994-01-10

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed