NO170079C - Fremgangsmaate for fremstilling av et krystallinsk torasemid - Google Patents

Fremgangsmaate for fremstilling av et krystallinsk torasemid

Info

Publication number
NO170079C
NO170079C NO863305A NO863305A NO170079C NO 170079 C NO170079 C NO 170079C NO 863305 A NO863305 A NO 863305A NO 863305 A NO863305 A NO 863305A NO 170079 C NO170079 C NO 170079C
Authority
NO
Norway
Prior art keywords
torasemid
crystalline
procedure
preparation
crystalline torasemid
Prior art date
Application number
NO863305A
Other languages
English (en)
Norwegian (no)
Other versions
NO863305D0 (no
NO863305L (no
NO170079B (no
Inventor
Fritz Topfmeier
Gustav Lettenbauer
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NO863305D0 publication Critical patent/NO863305D0/no
Publication of NO863305L publication Critical patent/NO863305L/no
Publication of NO170079B publication Critical patent/NO170079B/no
Publication of NO170079C publication Critical patent/NO170079C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Enzymes And Modification Thereof (AREA)
NO863305A 1985-08-17 1986-08-15 Fremgangsmaate for fremstilling av et krystallinsk torasemid NO170079C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853529529 DE3529529A1 (de) 1985-08-17 1985-08-17 Verfahren zur herstellung einer stabilen modifikation von torasemid

Publications (4)

Publication Number Publication Date
NO863305D0 NO863305D0 (no) 1986-08-15
NO863305L NO863305L (no) 1987-02-18
NO170079B NO170079B (no) 1992-06-01
NO170079C true NO170079C (no) 1992-09-09

Family

ID=6278766

Family Applications (1)

Application Number Title Priority Date Filing Date
NO863305A NO170079C (no) 1985-08-17 1986-08-15 Fremgangsmaate for fremstilling av et krystallinsk torasemid

Country Status (25)

Country Link
US (4) US4743693A (fi)
EP (1) EP0212537B1 (fi)
JP (2) JPS6245576A (fi)
KR (1) KR930009818B1 (fi)
AU (1) AU573454B2 (fi)
CA (1) CA1307277C (fi)
CS (2) CS259891B2 (fi)
DD (1) DD259858A5 (fi)
DE (2) DE3529529A1 (fi)
DK (1) DK162518C (fi)
ES (1) ES2001522A6 (fi)
FI (1) FI82189C (fi)
GR (1) GR862139B (fi)
HK (1) HK59994A (fi)
HU (1) HU195778B (fi)
IE (1) IE59237B1 (fi)
IL (1) IL79672A (fi)
LT (1) LT3596B (fi)
NO (1) NO170079C (fi)
NZ (1) NZ217172A (fi)
PL (1) PL146086B1 (fi)
PT (1) PT83186B (fi)
SU (1) SU1480766A3 (fi)
UA (1) UA7080A1 (fi)
ZA (1) ZA866151B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623620A1 (de) * 1986-07-12 1988-01-21 Boehringer Mannheim Gmbh Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung
US5166162A (en) * 1990-03-02 1992-11-24 Adir Et Compagnie Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
JP3586471B2 (ja) * 1991-06-25 2004-11-10 三菱ウェルファーマ株式会社 トラセミド含有医薬組成物
HRP980532B1 (en) 1998-10-02 2005-06-30 Pliva Novel crystalline torasemide modification
US5914336A (en) 1998-06-02 1999-06-22 Boehringer Mannheim Gmbh Method of controlling the serum solubility of orally administered torasemide and composition relating thereto
US6166045A (en) 1998-06-02 2000-12-26 Roche Diagnostics Gmbh Torasemide of modification III
US20030026835A1 (en) * 1999-02-15 2003-02-06 Sumitomo Pharmaceuticals Company Limited Tablets disintegrating rapidly in the oral cavity
US6465496B1 (en) 1999-08-11 2002-10-15 Teva Pharmaceutical Industries, Ltd. Torsemide polymorphs
TR200401462T4 (tr) * 2000-02-17 2004-08-23 Teva Pharmaceutical Industries Ltd. Torsemid modifikasyonu II' yi içeren dengeli bir farmasötik formülasyonu
HRP20000162B1 (en) * 2000-03-20 2004-06-30 Pliva D D Amorphous torasemide modification
CN1623987A (zh) 2000-03-20 2005-06-08 特瓦制药工业有限公司 托拉塞米的制备方法
HRP20000765A2 (en) * 2000-11-10 2002-06-30 Pliva D D Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (fi) * 2001-08-03 2004-03-06 Ranbaxy Lab
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
ITMI20020639A1 (it) * 2002-03-27 2003-09-29 Cosma S P A Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea
HRP20020603B1 (en) * 2002-07-19 2008-11-30 Pliva D.D. New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
DE03789888T1 (de) * 2002-11-18 2005-08-18 Teva Pharmaceutical Industries Ltd. Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol
US7678816B2 (en) * 2003-02-05 2010-03-16 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
ES2244324B1 (es) * 2004-03-25 2006-11-16 Ferrer Internacional, S.A. Composiciones diureticas de liberacion prolongada.
AT500576B1 (de) * 2004-07-28 2006-11-15 Sanochemia Pharmazeutika Ag Verfahren zur reindarstellung von kristallformen von torsemid
US10178893B1 (en) * 2013-06-14 2019-01-15 Scott Bradley Baker Shoe
FR3018688A1 (fr) * 2014-03-19 2015-09-25 Virbac Utilisation de torasemide a faible dose dans une composition veterinaire
EP3031471A1 (en) * 2014-12-12 2016-06-15 Ceva Sante Animale Veterinary composition for the treatment of pulmonary edema associated with heart failure in domestic animals
ES2703376T3 (es) * 2015-11-27 2019-03-08 Accupharma Spolka Z Ograniczona Odpowiedzialnoscia Preparación de combinación farmacéutica de inhibidor de ACE y diurético de bucle
CN115417810B (zh) * 2022-09-22 2023-10-10 南京正科医药股份有限公司 一种托拉塞米晶型ⅰ的精制方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US30633A (en) * 1860-11-13 Improvement in fire-escapes
GB1477664A (en) 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
LU85193A1 (fr) * 1984-01-31 1985-09-12 Christiaens Sa A Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation

Also Published As

Publication number Publication date
DK162518C (da) 1992-03-30
ZA866151B (en) 1987-04-29
PT83186A (de) 1986-09-01
HUT42069A (en) 1987-06-29
JPS6245576A (ja) 1987-02-27
HK59994A (en) 1994-07-08
NO863305D0 (no) 1986-08-15
JPH0415205B2 (fi) 1992-03-17
JPH0643400B2 (ja) 1994-06-08
PL261052A1 (en) 1987-11-02
JPH02191255A (ja) 1990-07-27
PL146086B1 (en) 1988-12-31
IL79672A (en) 1990-01-18
US4822807A (en) 1989-04-18
AU573454B2 (en) 1988-06-09
FI863305A0 (fi) 1986-08-15
CS259891B2 (en) 1988-11-15
IE59237B1 (en) 1994-01-26
KR870002076A (ko) 1987-03-30
DK385586D0 (da) 1986-08-13
AU6105586A (en) 1987-02-19
ES2001522A6 (es) 1988-06-01
USRE34672E (en) 1994-07-26
GR862139B (en) 1986-12-30
CS594586A2 (en) 1988-03-15
LT3596B (en) 1995-12-27
PT83186B (pt) 1988-07-01
CS419991A3 (en) 1992-06-17
NO863305L (no) 1987-02-18
DE3667970D1 (de) 1990-02-08
NO170079B (no) 1992-06-01
NZ217172A (en) 1989-02-24
CA1307277C (en) 1992-09-08
DK162518B (da) 1991-11-11
DE3529529A1 (de) 1987-02-19
USRE34580E (en) 1994-04-05
IE862179L (en) 1987-02-17
HU195778B (en) 1988-07-28
SU1480766A3 (ru) 1989-05-15
US4743693A (en) 1988-05-10
IL79672A0 (en) 1986-11-30
UA7080A1 (uk) 1995-06-30
DD259858A5 (de) 1988-09-07
KR930009818B1 (ko) 1993-10-11
FI82189C (fi) 1991-02-11
LTIP898A (en) 1995-03-27
FI82189B (fi) 1990-10-31
FI863305A (fi) 1987-02-18
DE3529529C2 (fi) 1987-05-27
EP0212537A1 (de) 1987-03-04
EP0212537B1 (de) 1990-01-03
DK385586A (da) 1987-02-18

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