DK162518C - Fremgangsmaade til fremstilling af en stabil modifikation af torasemid, samt et farmaceutisk praeparat indeholdende denne - Google Patents

Fremgangsmaade til fremstilling af en stabil modifikation af torasemid, samt et farmaceutisk praeparat indeholdende denne

Info

Publication number
DK162518C
DK162518C DK385586A DK385586A DK162518C DK 162518 C DK162518 C DK 162518C DK 385586 A DK385586 A DK 385586A DK 385586 A DK385586 A DK 385586A DK 162518 C DK162518 C DK 162518C
Authority
DK
Denmark
Prior art keywords
torasemide
preparing
procedure
pharmaceutical preparation
preparation containing
Prior art date
Application number
DK385586A
Other languages
Danish (da)
English (en)
Other versions
DK162518B (da
DK385586D0 (da
DK385586A (da
Inventor
Fritz Topfmeier
Gustav Lettenbauer
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of DK385586D0 publication Critical patent/DK385586D0/da
Publication of DK385586A publication Critical patent/DK385586A/da
Publication of DK162518B publication Critical patent/DK162518B/da
Application granted granted Critical
Publication of DK162518C publication Critical patent/DK162518C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK385586A 1985-08-17 1986-08-13 Fremgangsmaade til fremstilling af en stabil modifikation af torasemid, samt et farmaceutisk praeparat indeholdende denne DK162518C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853529529 DE3529529A1 (de) 1985-08-17 1985-08-17 Verfahren zur herstellung einer stabilen modifikation von torasemid
DE3529529 1985-08-17

Publications (4)

Publication Number Publication Date
DK385586D0 DK385586D0 (da) 1986-08-13
DK385586A DK385586A (da) 1987-02-18
DK162518B DK162518B (da) 1991-11-11
DK162518C true DK162518C (da) 1992-03-30

Family

ID=6278766

Family Applications (1)

Application Number Title Priority Date Filing Date
DK385586A DK162518C (da) 1985-08-17 1986-08-13 Fremgangsmaade til fremstilling af en stabil modifikation af torasemid, samt et farmaceutisk praeparat indeholdende denne

Country Status (25)

Country Link
US (4) US4743693A (fi)
EP (1) EP0212537B1 (fi)
JP (2) JPS6245576A (fi)
KR (1) KR930009818B1 (fi)
AU (1) AU573454B2 (fi)
CA (1) CA1307277C (fi)
CS (2) CS259891B2 (fi)
DD (1) DD259858A5 (fi)
DE (2) DE3529529A1 (fi)
DK (1) DK162518C (fi)
ES (1) ES2001522A6 (fi)
FI (1) FI82189C (fi)
GR (1) GR862139B (fi)
HK (1) HK59994A (fi)
HU (1) HU195778B (fi)
IE (1) IE59237B1 (fi)
IL (1) IL79672A (fi)
LT (1) LT3596B (fi)
NO (1) NO170079C (fi)
NZ (1) NZ217172A (fi)
PL (1) PL146086B1 (fi)
PT (1) PT83186B (fi)
SU (1) SU1480766A3 (fi)
UA (1) UA7080A1 (fi)
ZA (1) ZA866151B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3623620A1 (de) * 1986-07-12 1988-01-21 Boehringer Mannheim Gmbh Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung
US5166162A (en) * 1990-03-02 1992-11-24 Adir Et Compagnie Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
JP3586471B2 (ja) * 1991-06-25 2004-11-10 三菱ウェルファーマ株式会社 トラセミド含有医薬組成物
HRP980532B1 (en) * 1998-10-02 2005-06-30 Pliva Novel crystalline torasemide modification
US6166045A (en) 1998-06-02 2000-12-26 Roche Diagnostics Gmbh Torasemide of modification III
US5914336A (en) 1998-06-02 1999-06-22 Boehringer Mannheim Gmbh Method of controlling the serum solubility of orally administered torasemide and composition relating thereto
US20030026835A1 (en) * 1999-02-15 2003-02-06 Sumitomo Pharmaceuticals Company Limited Tablets disintegrating rapidly in the oral cavity
US6465496B1 (en) * 1999-08-11 2002-10-15 Teva Pharmaceutical Industries, Ltd. Torsemide polymorphs
MXPA03007908A (es) * 2000-02-17 2004-12-06 Teva Pharma Una formulacion farmaceutica estable que comprende una modificacion de torsemida ii.
HRP20000162B1 (en) * 2000-03-20 2004-06-30 Pliva D D Amorphous torasemide modification
CA2403382A1 (en) 2000-03-20 2001-09-27 Teva Pharmaceutical Industries Ltd. Novel processes for preparing torsemide intermediate
HRP20000765A2 (en) * 2000-11-10 2002-06-30 Pliva D D Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (fi) * 2001-08-03 2004-03-06 Ranbaxy Lab
EP2316468A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
ITMI20020639A1 (it) * 2002-03-27 2003-09-29 Cosma S P A Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea
HRP20020603B1 (en) * 2002-07-19 2008-11-30 Pliva D.D. New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
US7683080B2 (en) * 2002-11-18 2010-03-23 Teva Pharmaceutical Industries Ltd. Stable iansoprazole containing more than 500 ppm, up to about 3,000 ppm water and more than 200 ppm, up to about 5,000 ppm alcohol
CA2515130A1 (en) * 2003-02-05 2004-08-26 Teva Pharmaceutical Industries Ltd. Method of stabilizing lansoprazole
ES2244324B1 (es) * 2004-03-25 2006-11-16 Ferrer Internacional, S.A. Composiciones diureticas de liberacion prolongada.
AT500576B1 (de) * 2004-07-28 2006-11-15 Sanochemia Pharmazeutika Ag Verfahren zur reindarstellung von kristallformen von torsemid
US10178893B1 (en) * 2013-06-14 2019-01-15 Scott Bradley Baker Shoe
FR3018688A1 (fr) * 2014-03-19 2015-09-25 Virbac Utilisation de torasemide a faible dose dans une composition veterinaire
EP3031471A1 (en) 2014-12-12 2016-06-15 Ceva Sante Animale Veterinary composition for the treatment of pulmonary edema associated with heart failure in domestic animals
SI3173075T1 (sl) * 2015-11-27 2019-02-28 Accupharma Spolka Z Ograniczona Odpowiedzialnoscia Farmacevtski kombinacijski pripravek inhibitorja ACE in diuretika zanke
CN115417810B (zh) * 2022-09-22 2023-10-10 南京正科医药股份有限公司 一种托拉塞米晶型ⅰ的精制方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US30633A (en) * 1860-11-13 Improvement in fire-escapes
GB1477664A (en) * 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
GB1593609A (en) * 1978-01-31 1981-07-22 Christiaens Sa A Pyridine sulfonamides
LU85193A1 (fr) * 1984-01-31 1985-09-12 Christiaens Sa A Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation

Also Published As

Publication number Publication date
EP0212537A1 (de) 1987-03-04
DK162518B (da) 1991-11-11
GR862139B (en) 1986-12-30
HUT42069A (en) 1987-06-29
DK385586D0 (da) 1986-08-13
DE3529529A1 (de) 1987-02-19
CS594586A2 (en) 1988-03-15
HU195778B (en) 1988-07-28
FI82189B (fi) 1990-10-31
USRE34672E (en) 1994-07-26
IE862179L (en) 1987-02-17
NO863305D0 (no) 1986-08-15
LT3596B (en) 1995-12-27
PT83186B (pt) 1988-07-01
NO170079C (no) 1992-09-09
US4822807A (en) 1989-04-18
USRE34580E (en) 1994-04-05
CS419991A3 (en) 1992-06-17
DK385586A (da) 1987-02-18
UA7080A1 (uk) 1995-06-30
KR930009818B1 (ko) 1993-10-11
PL146086B1 (en) 1988-12-31
DE3667970D1 (de) 1990-02-08
DE3529529C2 (fi) 1987-05-27
JPH0643400B2 (ja) 1994-06-08
CA1307277C (en) 1992-09-08
PL261052A1 (en) 1987-11-02
NO170079B (no) 1992-06-01
CS259891B2 (en) 1988-11-15
FI863305A (fi) 1987-02-18
US4743693A (en) 1988-05-10
SU1480766A3 (ru) 1989-05-15
AU6105586A (en) 1987-02-19
DD259858A5 (de) 1988-09-07
IL79672A0 (en) 1986-11-30
IL79672A (en) 1990-01-18
LTIP898A (en) 1995-03-27
NO863305L (no) 1987-02-18
PT83186A (de) 1986-09-01
JPH0415205B2 (fi) 1992-03-17
ES2001522A6 (es) 1988-06-01
IE59237B1 (en) 1994-01-26
FI863305A0 (fi) 1986-08-15
KR870002076A (ko) 1987-03-30
EP0212537B1 (de) 1990-01-03
HK59994A (en) 1994-07-08
FI82189C (fi) 1991-02-11
JPS6245576A (ja) 1987-02-27
JPH02191255A (ja) 1990-07-27
ZA866151B (en) 1987-04-29
NZ217172A (en) 1989-02-24
AU573454B2 (en) 1988-06-09

Similar Documents

Publication Publication Date Title
DK162518C (da) Fremgangsmaade til fremstilling af en stabil modifikation af torasemid, samt et farmaceutisk praeparat indeholdende denne
DK165594C (da) (-)-benzhydrylsulfinylacetamid, fremgangsmaade til fremstilling heraf, terapeutisk praeparat indeholdende denne forbindelse, samt anvendelse af forbindelsen til fremstilling af et laegemiddel
DK164868C (da) Imidazooe4,5-baaquinolin-2-on-derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
DK407588D0 (da) Oxadiazolforbindelse, farmaceutisk praeparat indeholdende en saadan forbindelse, anvendelse af forbindelsen til fremstilling af et laegemiddel samt fremgangsmaade til fremstilling af en saadan forbindelse
DK161709C (da) 13-alkyl-11beta-phenylgonaner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater indeholdende dem samt deres anvendelse til fremstilling af laegemidler
DK160985C (da) Asymmetriske diestere af 1,4-dihydro-2,6-dimethyl-pyridin-3,5-dicarboxylsyre, fremgangsmaader til fremstilling heraf samt farmaceutiske praeparater indeholdende disse
DK163991C (da) Dichloranilinderivater, fremgangsmaade til fremstilling af disse, samt farmaceutiske praeparater indeholdende derivaterne
DK610988A (da) Polypeptider, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater der indeholder dem samt anvendelse deraf til fremstilling af et laegemiddel
DK181586A (da) 2,5-diaryltetrahydrofuran, farmaceutisk praeparat indeholdendeen saadan forbindelse og fremgangsmaade til fremstilling af en saadan forbindelse
DK526586A (da) Tetraalkylethenylidenbisphosphonater, fremgangsmaade til fremstilling af disse samt farmaceutisk sammensaetning indeholdende samme
DK83386A (da) Disaccharid- og trisaccharid-derivater af ''lipid a''-typen, praeparater der indeholder disse samt fremgangsmaade til fremstilling af disse
DK164149C (da) Fremgangsmaade til fremstilling af et praeparat indeholdende methylhydroxyprogesteronacetat samt farmaceutisk praeparat indeholdende stoffet
DK342187A (da) 4-pyridin-derivater, fremgangsmaade til fremstilling af saadanne derivater samt farmaceutiske praeparater indeholdende disse
DK573386A (da) Laegemiddel indeholdende en ekstrakt af planter af slaegten caesalpinia samt fremgangsmaade til fremstilling af et saadant laegemiddel
DK66086D0 (da) Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse
DK60486D0 (da) Derivater af 2-(4,5-dihydro-2-1h-imidazolyl)-2,3-dihydroindol, fremgangsmaade til fremstilling af samt laegemiddel indeholdende saadannederivater
DK191086D0 (da) Benzisoselenazolonylderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
DK163512C (da) Substituerede azacyclohexylderivater af rifamyciner og salte deraf, farmaceutiske praeparater indeholdende disse forbindelser samt en fremgangsmaade til fremstilling af forbindelserne
DK553689D0 (da) Phenyloxypropanolaminderivater, fremgangsmaade til fremstilling af saadanne forbindelser samt laegemiddel indeholdende disse
DK63786D0 (da) Aromatiske alkanderivater, skadedyrsbekaempelsesmidler indeholdende disse forbindelser samt fremgangsmaade til deres fremstilling
DK645988A (da) Biphenylderivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeprater indeholdende samme
DK65986A (da) Dihydropyridiner, fremgangsmaader til fremstilling heraf samt farmaceutiske midler indeholdende disse
DK561787A (da) Thiadiazol-derivat, fremgangsmaade til fremstilling af dette, farmaceutisk praeparat indeholdende dette samt anvendelse af dette til fremstilling af et laegemiddel
DK65686A (da) Dihydropyridiner, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse
DK369088D0 (da) Fremgangsmaade til fremstilling af nukleinsyrederivater og fremgangsmaade til fremstilling af farmaceutiske praeparater indeholdende disse

Legal Events

Date Code Title Description
PUP Patent expired