NO169290C - Analogifremgangsmaate for fremstilling av et terapeutisk aktivt tetrapyrrol-amino-dicarboxylsyreaddukt - Google Patents
Analogifremgangsmaate for fremstilling av et terapeutisk aktivt tetrapyrrol-amino-dicarboxylsyreadduktInfo
- Publication number
- NO169290C NO169290C NO852871A NO852871A NO169290C NO 169290 C NO169290 C NO 169290C NO 852871 A NO852871 A NO 852871A NO 852871 A NO852871 A NO 852871A NO 169290 C NO169290 C NO 169290C
- Authority
- NO
- Norway
- Prior art keywords
- preparing
- amino
- tetrapyrrol
- dicarboxylic acid
- therapeutic active
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000004952 Polyamide Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920002647 polyamide Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0036—Porphyrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0052—Small organic molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Medicinal Preparation (AREA)
- Rolls And Other Rotary Bodies (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/631,925 US4675338A (en) | 1984-07-18 | 1984-07-18 | Tetrapyrrole therapeutic agents |
Publications (3)
Publication Number | Publication Date |
---|---|
NO852871L NO852871L (no) | 1986-01-20 |
NO169290B NO169290B (no) | 1992-02-24 |
NO169290C true NO169290C (no) | 1992-06-03 |
Family
ID=24533344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO852871A NO169290C (no) | 1984-07-18 | 1985-07-18 | Analogifremgangsmaate for fremstilling av et terapeutisk aktivt tetrapyrrol-amino-dicarboxylsyreaddukt |
Country Status (11)
Country | Link |
---|---|
US (1) | US4675338A (no) |
EP (1) | EP0168832B1 (no) |
JP (2) | JPH0688902B2 (no) |
AT (1) | ATE94547T1 (no) |
AU (1) | AU579387B2 (no) |
CA (1) | CA1262862A (no) |
DE (1) | DE3587579T2 (no) |
DK (1) | DK167768B1 (no) |
HK (1) | HK135994A (no) |
NO (1) | NO169290C (no) |
SG (1) | SG103194G (no) |
Families Citing this family (99)
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US4649151A (en) * | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
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JPS61186385A (ja) * | 1985-02-13 | 1986-08-20 | Sato Yakugaku Kenkyusho:Kk | デユウテロポルフイリン誘導体及びその塩 |
US5066274A (en) * | 1985-04-30 | 1991-11-19 | Nippon Petrochemicals Company, Ltd. | Tetrapyrrole therapeutic agents |
ATE91625T1 (de) * | 1985-04-30 | 1993-08-15 | Nippon Petrochemicals Co Ltd | Verwendung von porphyrinderivaten bei der entdeckung und behandlung von tumoren. |
JPS625986A (ja) * | 1985-04-30 | 1987-01-12 | Nippon Petrochem Co Ltd | 新規なテトラピロ−ル化合物 |
US4977177A (en) * | 1985-04-30 | 1990-12-11 | Nippon Petrochemicals Company, Ltd. | Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents |
US4656186A (en) * | 1985-04-30 | 1987-04-07 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
DE3687399T2 (de) * | 1985-10-23 | 1993-04-29 | Nihon Mediphysics Co Ltd | Porphyrinderivate, ihre herstellung und verwendung. |
US5216012A (en) * | 1986-01-02 | 1993-06-01 | University Of Toledo | Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
US5051415A (en) * | 1986-01-02 | 1991-09-24 | The University Of Toledo | Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
US5534506A (en) * | 1986-01-02 | 1996-07-09 | University Of Toledo | Use of purpurins, chlorins and purpurin- and chlorin-containing compositions |
US4772681A (en) * | 1986-01-17 | 1988-09-20 | Hamari Chemicals, Ltd. | Porphyrin derivatives |
US4877872A (en) * | 1986-06-24 | 1989-10-31 | The University Of Toledo | Production and use of dimers of hematoporophyrin, purpurins, chlorines and purpurin- and chlorin-complexes |
US5171749A (en) * | 1987-01-20 | 1992-12-15 | University Of British Columbia | Wavelength-specific cytotoxic agents |
US4883790A (en) * | 1987-01-20 | 1989-11-28 | University Of British Columbia | Wavelength-specific cytotoxic agents |
US5283255A (en) * | 1987-01-20 | 1994-02-01 | The University Of British Columbia | Wavelength-specific cytotoxic agents |
US4920143A (en) * | 1987-04-23 | 1990-04-24 | University Of British Columbia | Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents |
US5095030A (en) * | 1987-01-20 | 1992-03-10 | University Of British Columbia | Wavelength-specific cytotoxic agents |
JPH0629196B2 (ja) * | 1987-12-01 | 1994-04-20 | 甲子郎 梅村 | 超音波による腫瘍治療用生理作用増強剤 |
US5004811A (en) * | 1987-12-24 | 1991-04-02 | Nippon Petrochemicals Company, Ltd. | Tetrapyrrole aminocarboxylic acids |
US5192788A (en) * | 1988-05-23 | 1993-03-09 | Georgia State University Foundation, Inc. | Porphyrin antiviral compositions |
US5109016A (en) * | 1988-05-23 | 1992-04-28 | Georgia State University Foundation, Inc. | Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions |
US4925736A (en) * | 1988-07-06 | 1990-05-15 | Long Island Jewish Medical Center | Topical hematoporphyrin |
DE3827940A1 (de) * | 1988-08-13 | 1990-03-01 | Schering Ag | 13,17-propionsaeure- und propionsaeurederivat- substituierte porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
US4959356A (en) * | 1989-05-26 | 1990-09-25 | The United States Of America As Represented By The United States Department Of Energy | Porphyrins for boron neutron capture therapy |
US4997639A (en) * | 1989-11-27 | 1991-03-05 | Nippon Petrochemicals Company, Limited | Method for detecting cholesterol deposited in bodies of mammals |
US5238940A (en) * | 1990-03-22 | 1993-08-24 | Quadra Logic Technologies Inc. | Compositions for photodynamic therapy |
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US5219878A (en) * | 1990-10-05 | 1993-06-15 | Queen's University | Tetrapyrrole hydroxyalkylamide photochemotherapeutic agents |
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JP3154742B2 (ja) * | 1991-04-30 | 2001-04-09 | 日本石油化学株式会社 | 哺乳類の動脈硬化症治療剤 |
US5330741A (en) * | 1992-02-24 | 1994-07-19 | The Regents Of The University Of California | Long-wavelength water soluble chlorin photosensitizers useful for photodynamic therapy and diagnosis of tumors |
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US4393071A (en) * | 1975-03-17 | 1983-07-12 | Naoharu Fujii | Method of treating gastric, mammary, lung and uterus tumors |
JPS53112900A (en) * | 1977-03-14 | 1978-10-02 | Ajinomoto Co Inc | Porphyrin derivative |
JPS58201791A (ja) * | 1982-05-19 | 1983-11-24 | Katsuo Unno | ヘマトポルフイリン誘導体 |
ATE53204T1 (de) * | 1982-09-27 | 1990-06-15 | Photofrin Medical Inc | Gereinigte hematoporphyrinabkoemmlinge fuer diagnose und tumorbehandlung sowie verfahren. |
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JPS60158687A (ja) * | 1984-01-27 | 1985-08-20 | Matsushita Electric Ind Co Ltd | 半導体レ−ザ |
JPS60158686A (ja) * | 1984-01-27 | 1985-08-20 | Matsushita Electric Ind Co Ltd | 半導体レ−ザ |
US4693885A (en) * | 1984-07-18 | 1987-09-15 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
US4675338A (en) * | 1984-07-18 | 1987-06-23 | Nippon Petrochemicals Co., Ltd. | Tetrapyrrole therapeutic agents |
-
1984
- 1984-07-18 US US06/631,925 patent/US4675338A/en not_active Expired - Lifetime
-
1985
- 1985-07-18 AU AU45158/85A patent/AU579387B2/en not_active Expired
- 1985-07-18 EP EP85108987A patent/EP0168832B1/en not_active Expired - Lifetime
- 1985-07-18 JP JP60158686A patent/JPH0688902B2/ja not_active Expired - Lifetime
- 1985-07-18 CA CA000487040A patent/CA1262862A/en not_active Expired
- 1985-07-18 DE DE85108987T patent/DE3587579T2/de not_active Expired - Lifetime
- 1985-07-18 JP JP60158687A patent/JPH0689000B2/ja not_active Expired - Lifetime
- 1985-07-18 NO NO852871A patent/NO169290C/no not_active IP Right Cessation
- 1985-07-18 AT AT85108987T patent/ATE94547T1/de not_active IP Right Cessation
- 1985-07-18 DK DK326785A patent/DK167768B1/da not_active IP Right Cessation
-
1994
- 1994-07-26 SG SG103194A patent/SG103194G/en unknown
- 1994-12-01 HK HK135994A patent/HK135994A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU579387B2 (en) | 1988-11-24 |
DE3587579T2 (de) | 1994-02-17 |
CA1262862C (en) | 1989-11-14 |
EP0168832A2 (en) | 1986-01-22 |
JPH0688902B2 (ja) | 1994-11-09 |
JPS6183186A (ja) | 1986-04-26 |
CA1262862A (en) | 1989-11-14 |
NO852871L (no) | 1986-01-20 |
ATE94547T1 (de) | 1993-10-15 |
EP0168832B1 (en) | 1993-09-15 |
NO169290B (no) | 1992-02-24 |
JPH0689000B2 (ja) | 1994-11-09 |
AU4515885A (en) | 1986-03-27 |
DE3587579D1 (de) | 1993-10-21 |
DK167768B1 (da) | 1993-12-13 |
US4675338A (en) | 1987-06-23 |
SG103194G (en) | 1994-10-28 |
DK326785A (da) | 1986-01-19 |
HK135994A (en) | 1994-12-09 |
JPS61129163A (ja) | 1986-06-17 |
DK326785D0 (da) | 1985-07-18 |
EP0168832A3 (en) | 1988-05-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |