DE3381616D1 - Gereinigte hemaf 3381400inabkoemmlinge fuer diagnose und tumorbehandlung sowie verfahren. - Google Patents

Gereinigte hemaf 3381400inabkoemmlinge fuer diagnose und tumorbehandlung sowie verfahren.

Info

Publication number
DE3381616D1
DE3381616D1 DE8383903067T DE3381616T DE3381616D1 DE 3381616 D1 DE3381616 D1 DE 3381616D1 DE 8383903067 T DE8383903067 T DE 8383903067T DE 3381616 T DE3381616 T DE 3381616T DE 3381616 D1 DE3381616 D1 DE 3381616D1
Authority
DE
Germany
Prior art keywords
tumors
molecular weight
diagnosis
substance
hematoporphyrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8383903067T
Other languages
English (en)
Inventor
R Weishaupt
J Dougherty
R Potter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Health Research Inc
Original Assignee
PHOTOFRIN MEDICAL Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PHOTOFRIN MEDICAL Inc filed Critical PHOTOFRIN MEDICAL Inc
Application granted granted Critical
Publication of DE3381616D1 publication Critical patent/DE3381616D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE8383903067T 1982-09-27 1983-09-09 Gereinigte hemaf 3381400inabkoemmlinge fuer diagnose und tumorbehandlung sowie verfahren. Expired - Lifetime DE3381616D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42464782A 1982-09-27 1982-09-27
US48134583A 1983-04-01 1983-04-01
PCT/US1983/001379 WO1984001382A1 (en) 1982-09-27 1983-09-09 Purified hematoporphyrin derivative for diagnosis and treatment of tumors, and method

Publications (1)

Publication Number Publication Date
DE3381616D1 true DE3381616D1 (de) 1990-07-05

Family

ID=27026406

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383903067T Expired - Lifetime DE3381616D1 (de) 1982-09-27 1983-09-09 Gereinigte hemaf 3381400inabkoemmlinge fuer diagnose und tumorbehandlung sowie verfahren.

Country Status (10)

Country Link
EP (1) EP0120054B1 (de)
JP (1) JPS60500132A (de)
AT (1) ATE53204T1 (de)
AU (1) AU581840B2 (de)
CA (1) CA1271746A (de)
DE (1) DE3381616D1 (de)
DK (1) DK172284B1 (de)
NL (1) NL940021I2 (de)
NO (1) NO166284C (de)
WO (1) WO1984001382A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649151A (en) * 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins
US4675338A (en) * 1984-07-18 1987-06-23 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US4693885A (en) * 1984-07-18 1987-09-15 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US5104637A (en) * 1985-02-06 1992-04-14 University Of Cincinnati Radio labeled dihematophorphyrin ether and its use in detecting and treating neoplastic tissue
US4977177A (en) * 1985-04-30 1990-12-11 Nippon Petrochemicals Company, Ltd. Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents
EP0210351B1 (de) * 1985-04-30 1993-07-21 Nippon Petrochemicals Co., Ltd. Verwendung von Porphyrinderivaten bei der Entdeckung und Behandlung von Tumoren
US4656186A (en) 1985-04-30 1987-04-07 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents
US5066274A (en) * 1985-04-30 1991-11-19 Nippon Petrochemicals Company, Ltd. Tetrapyrrole therapeutic agents
GB8522670D0 (en) * 1985-09-13 1985-10-16 Efamol Ltd Drug treatments
ATE84036T1 (de) * 1985-10-23 1993-01-15 Nihon Mediphysics Co Ltd Porphyrinderivate, ihre herstellung und verwendung.
US5534506A (en) * 1986-01-02 1996-07-09 University Of Toledo Use of purpurins, chlorins and purpurin- and chlorin-containing compositions
US5051415A (en) * 1986-01-02 1991-09-24 The University Of Toledo Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions
US5216012A (en) * 1986-01-02 1993-06-01 University Of Toledo Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions
CA1340951C (en) * 1986-01-02 2000-04-11 Alan R. Moragn Production and use of purpurins, chlorins and purpurin-and chlorin-containing compositions
US4882234A (en) * 1986-11-12 1989-11-21 Healux, Inc. Storage-stable porphin compositions and a method for their manufacture
US4920143A (en) * 1987-04-23 1990-04-24 University Of British Columbia Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US5171749A (en) * 1987-01-20 1992-12-15 University Of British Columbia Wavelength-specific cytotoxic agents
US5283255A (en) * 1987-01-20 1994-02-01 The University Of British Columbia Wavelength-specific cytotoxic agents
US4925736A (en) * 1988-07-06 1990-05-15 Long Island Jewish Medical Center Topical hematoporphyrin
USRE39094E1 (en) 1988-07-20 2006-05-09 Health Research, Inc. Pyropheophorbides and their use in photodynamic therapy
USRE38994E1 (en) 1988-07-20 2006-02-28 Health Research, Inc. Pyropheophorbides conjugates and their use in photodynamic therapy
GB2254417A (en) * 1991-04-05 1992-10-07 Bijan Jouza Photodynamic laser detection for cancer diagnosis
NL9200143A (nl) * 1992-01-27 1993-08-16 Seehof Lab F & E Ges Werkwijze voor de bereiding van een actief middel te gebruiken voor de fotodynamische therapie en voor het vaststellen van een diagnose, therapeutisch middel en diagnosticum dat het actief middel bevat en farmaceutische samenstelling.
US5948061A (en) 1996-10-29 1999-09-07 Double Click, Inc. Method of delivery, targeting, and measuring advertising over networks
WO2000008802A2 (en) 1998-08-03 2000-02-17 Doubleclick Inc. Network for distribution of re-targeted advertising
US7897140B2 (en) 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
US6624187B1 (en) 2000-06-12 2003-09-23 Health Research, Inc. Long wave length absorbing bacteriochlorin alkyl ether analogs
EP1517684B1 (de) 2002-06-27 2009-07-22 Health Research, Inc. Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie

Also Published As

Publication number Publication date
DK261384A (da) 1984-05-25
EP0120054B1 (de) 1990-05-30
EP0120054A1 (de) 1984-10-03
NO166284B (no) 1991-03-18
CA1271746A (en) 1990-07-17
EP0120054A4 (de) 1985-04-11
NL940021I2 (nl) 1997-05-01
NO842089L (no) 1984-05-25
AU581840B2 (en) 1989-03-09
DK261384D0 (da) 1984-05-25
DK172284B1 (da) 1998-02-23
NO166284C (no) 1991-06-26
WO1984001382A1 (en) 1984-04-12
AU2032283A (en) 1984-04-24
NL940021I1 (nl) 1997-03-03
JPS60500132A (ja) 1985-01-31
ATE53204T1 (de) 1990-06-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: HEALTH RESEARCH INC., BUFFALO, N.Y., US

8364 No opposition during term of opposition
V448 Application of spc

Free format text: PRODUCT NAME: PORFIMER, GGF. IN DER FORM EINES PHARMAZEUTISCH VERTRAEGLICHEN SALZES, INSBESONDERE PORFIMER-NATRIUM; REGISTRATION NO/DATE: 31013.00.00, 19970714; 31013.01.00, 19970714; 31011.00.00, 19970715; 31011.01.00, 19970715

Spc suppl protection certif: 198 75 002

Filing date: 19980113

V454 Spc application withdrawn or to be regarded as withdrawn

Free format text: PRODUCT NAME: PORFIMER, GGF. IN DER FORM EINES PHARMAZEUTISCH VERTRAEGLICHEN SALZES, INSBESONDERE PORFIMER-NATRIUM; REGISTRATION NO/DATE: 31013.00.00, 19970714; 31013.01.00, 19970714; 31011.00.00, 19970715; 31011.01.00, 19970715

Spc suppl protection certif: 198 75 002

Filing date: 19980113