NO168944C - Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenylalanin-methylester eller hydrokloridet derav - Google Patents

Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenylalanin-methylester eller hydrokloridet derav

Info

Publication number
NO168944C
NO168944C NO861189A NO861189A NO168944C NO 168944 C NO168944 C NO 168944C NO 861189 A NO861189 A NO 861189A NO 861189 A NO861189 A NO 861189A NO 168944 C NO168944 C NO 168944C
Authority
NO
Norway
Prior art keywords
aspartyl
alfa
hydrochloride
procedure
preparation
Prior art date
Application number
NO861189A
Other languages
English (en)
Other versions
NO861189L (no
NO168944B (no
Inventor
Ryuichi Mita
Toshio Katoh
Chojiro Higuchi
Takeshi Oura
Akihiro Yamaguchi
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5955785A external-priority patent/JPH07637B2/ja
Priority claimed from JP6609585A external-priority patent/JPH07639B2/ja
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of NO861189L publication Critical patent/NO861189L/no
Publication of NO168944B publication Critical patent/NO168944B/no
Publication of NO168944C publication Critical patent/NO168944C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
NO861189A 1985-03-26 1986-03-25 Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenylalanin-methylester eller hydrokloridet derav NO168944C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5955785A JPH07637B2 (ja) 1985-03-26 1985-03-26 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩を製造する方法
JP6609585A JPH07639B2 (ja) 1985-03-29 1985-03-29 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法

Publications (3)

Publication Number Publication Date
NO861189L NO861189L (no) 1986-09-29
NO168944B NO168944B (no) 1992-01-13
NO168944C true NO168944C (no) 1992-04-22

Family

ID=26400602

Family Applications (1)

Application Number Title Priority Date Filing Date
NO861189A NO168944C (no) 1985-03-26 1986-03-25 Fremgangsmaate for fremstilling av alfa-l-aspartyl-l-fenylalanin-methylester eller hydrokloridet derav

Country Status (11)

Country Link
US (1) US4778916A (no)
EP (1) EP0200311B1 (no)
KR (1) KR890005038B1 (no)
AU (1) AU561384B2 (no)
BR (1) BR8601335A (no)
CA (1) CA1278400C (no)
DE (1) DE3674830D1 (no)
ES (1) ES8705365A1 (no)
MX (1) MX161989A (no)
NO (1) NO168944C (no)
SU (1) SU1556542A3 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof
DE3600731A1 (de) * 1986-01-13 1987-07-16 Green Cross Korea Verfahren zur herstellung von (alpha)-l-aspartyl-l-phenylalaninmethylester
ES2042583T3 (es) * 1986-12-05 1993-12-16 Mitsui Toatsu Chemicals Preparacion de metil ester de alpha-l-aspartil-l-fenil-alanina o uno de sus hidrohaluros.
NL8701035A (nl) * 1987-05-01 1988-12-01 Stamicarbon Werkwijze voor de bereiding van aspartylfenylalaninemethylester uit n-formylaspartylfenylalaninemethylester.
JP2910228B2 (ja) * 1990-11-20 1999-06-23 味の素株式会社 α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステル塩酸塩の製法
JP2979761B2 (ja) * 1991-05-23 1999-11-15 味の素株式会社 α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステル塩酸塩の製造法
JPH05117246A (ja) * 1991-10-23 1993-05-14 Ajinomoto Co Inc 新規２，５−ジオキソピペラジン化合物とその製造法及びα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル誘導体の製造法
CN102206246A (zh) * 2011-04-18 2011-10-05 吴江 水相合成N-甲酰-α-L-天门冬氨酰-L-苯丙氨酸的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
JPS4896557A (no) * 1972-03-22 1973-12-10
CA1028197A (en) * 1973-04-02 1978-03-21 Jeffrey H. Berg Concentrated liquid low calorie sweetener
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5140069A (no) * 1974-10-02 1976-04-03 Hitachi Ltd
JPS5823380B2 (ja) * 1974-12-05 1983-05-14 味の素株式会社 ホルミルキノ ダツリホウ
JPS51113841A (en) * 1975-03-28 1976-10-07 Ajinomoto Co Inc Process for preparing lower alkyl esters of n-formyl-alpha -l-aspartyl-l-phenylalanine
US4088649A (en) * 1975-07-02 1978-05-09 Firmenich S.A. Process for preparing a diketo-piperazine
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
MX4704E (es) * 1976-12-27 1982-08-04 Monsanto Co Procedimiento mejorado para la preparacion de ester metilico de alfa-l-aspartil-l-fenilalanina
JPS5526133A (en) * 1978-08-11 1980-02-25 Hitachi Ltd Gripper for tension reel drum
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
GB2133409B (en) * 1983-01-13 1986-03-05 Erba Farmitalia Aspartame synthesis
GB8300810D0 (en) * 1983-01-13 1983-02-16 Erba Farmitalia Aspartame synthesis
JPH0631312B2 (ja) * 1983-03-18 1994-04-27 味の素株式会社 ジペプチド結晶及びその製造方法
JPS59219258A (ja) * 1983-05-28 1984-12-10 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
JPS59225152A (ja) * 1983-06-02 1984-12-18 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
JPH0613550B2 (ja) * 1983-06-03 1994-02-23 味の素株式会社 α―Ｌ―アスパルチル―Ｌ―フェニルアラニン―低級アルキルエステルの製造法
JPS6050200A (ja) * 1983-08-30 1985-03-19 Nippon Kokan Kk <Nkk> 金属ストリップのクリーニング洗浄液の浄化装置
JPS60174799A (ja) * 1984-02-21 1985-09-09 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法
ES8703487A1 (es) * 1984-12-27 1987-03-01 Mitsui Toatsu Chemicals Procedimiento para la preparacion de a-l-aspartil-l-fenila- lanina metil ester
JPS61174799A (ja) * 1985-01-30 1986-08-06 日本電気ホームエレクトロニクス株式会社 リ−ド線付円柱状部品の自動供給取付装置
AU561384B2 (en) * 1985-03-26 1987-05-07 Mitsui Toatsu Chemicals Inc. Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof

Also Published As

Publication number Publication date
EP0200311A3 (en) 1987-10-28
ES553390A0 (es) 1987-05-16
NO861189L (no) 1986-09-29
DE3674830D1 (de) 1990-11-15
AU5435486A (en) 1986-10-02
EP0200311B1 (en) 1990-10-10
SU1556542A3 (ru) 1990-04-07
KR890005038B1 (ko) 1989-12-08
ES8705365A1 (es) 1987-05-16
AU561384B2 (en) 1987-05-07
EP0200311A2 (en) 1986-11-05
KR860007283A (ko) 1986-10-10
NO168944B (no) 1992-01-13
BR8601335A (pt) 1986-12-02
MX161989A (es) 1991-03-18
CA1278400C (en) 1990-12-27
US4778916A (en) 1988-10-18

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