NO162470C - Analogifremgangsmaate for fremstilling av terapeutisk aktiv ester av 7beta-(2-(2-amino-tiazol-4-yl)acetamido)-3-(((1-(2-dimetylamino-etyl)-1h-tetrazol-5-yl)tio)metyl)-cef-3-em-4-karboksylsyre. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktiv ester av 7beta-(2-(2-amino-tiazol-4-yl)acetamido)-3-(((1-(2-dimetylamino-etyl)-1h-tetrazol-5-yl)tio)metyl)-cef-3-em-4-karboksylsyre.

Info

Publication number
NO162470C
NO162470C NO842224A NO842224A NO162470C NO 162470 C NO162470 C NO 162470C NO 842224 A NO842224 A NO 842224A NO 842224 A NO842224 A NO 842224A NO 162470 C NO162470 C NO 162470C
Authority
NO
Norway
Prior art keywords
dimetylamino
tiazol
7beta
ceph
tetrazol
Prior art date
Application number
NO842224A
Other languages
English (en)
Norwegian (no)
Other versions
NO162470B (no
NO842224L (no
Inventor
Tatsuo Nishimura
Yoshinobu Yoshimura
Mitsuo Numata
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58099212A external-priority patent/JPS59225192A/ja
Priority claimed from JP59076834A external-priority patent/JPS60218394A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO842224L publication Critical patent/NO842224L/no
Publication of NO162470B publication Critical patent/NO162470B/no
Publication of NO162470C publication Critical patent/NO162470C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO842224A 1983-06-02 1984-06-01 Analogifremgangsmaate for fremstilling av terapeutisk aktiv ester av 7beta-(2-(2-amino-tiazol-4-yl)acetamido)-3-(((1-(2-dimetylamino-etyl)-1h-tetrazol-5-yl)tio)metyl)-cef-3-em-4-karboksylsyre. NO162470C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58099212A JPS59225192A (ja) 1983-06-02 1983-06-02 セフアロスポリンエステル誘導体
JP59076834A JPS60218394A (ja) 1984-04-16 1984-04-16 セフアロスポリンエステル誘導体

Publications (3)

Publication Number Publication Date
NO842224L NO842224L (no) 1984-12-03
NO162470B NO162470B (no) 1989-09-25
NO162470C true NO162470C (no) 1990-01-10

Family

ID=26417948

Family Applications (1)

Application Number Title Priority Date Filing Date
NO842224A NO162470C (no) 1983-06-02 1984-06-01 Analogifremgangsmaate for fremstilling av terapeutisk aktiv ester av 7beta-(2-(2-amino-tiazol-4-yl)acetamido)-3-(((1-(2-dimetylamino-etyl)-1h-tetrazol-5-yl)tio)metyl)-cef-3-em-4-karboksylsyre.

Country Status (22)

Country Link
US (1) US5120841A (da)
EP (1) EP0128029B1 (da)
KR (1) KR910008350B1 (da)
AR (2) AR240825A1 (da)
AT (1) ATE40691T1 (da)
AU (1) AU566096B2 (da)
BG (1) BG60500B2 (da)
CA (1) CA1216285A (da)
DE (1) DE3476662D1 (da)
DK (1) DK273784A (da)
ES (4) ES533051A0 (da)
FI (1) FI75574C (da)
GR (1) GR79941B (da)
HK (1) HK9492A (da)
HU (1) HU192028B (da)
IN (1) IN158586B (da)
MY (1) MY101993A (da)
NO (1) NO162470C (da)
NZ (1) NZ208281A (da)
PH (1) PH19575A (da)
PT (1) PT78684B (da)
SG (1) SG392G (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0010475D0 (en) * 2000-04-28 2000-06-14 Biochemie Gmbh Organic compounds
CN101993449B (zh) * 2009-08-13 2012-10-31 丽珠医药集团股份有限公司 高纯度头孢替安酯及其二盐酸盐的制备方法
CN102241692A (zh) * 2010-05-14 2011-11-16 广州白云山制药股份有限公司广州白云山制药总厂 溶媒结晶法制备头孢替安酯盐酸盐的方法
CN101948476B (zh) * 2010-09-19 2012-07-25 苏州致君万庆药业有限公司 一种头孢替安酯盐酸盐的制备方法
CN102424687A (zh) * 2011-11-01 2012-04-25 湖南方盛制药股份有限公司 盐酸头孢替安酯的制备方法
CN102898441A (zh) * 2012-10-11 2013-01-30 南通康鑫药业有限公司 一种头孢替安的合成方法
CN103012436B (zh) * 2012-12-04 2015-07-01 山东鑫泉医药有限公司 头孢替安盐酸盐的制备方法
CN104031068A (zh) * 2014-06-11 2014-09-10 济南诚汇双达化工有限公司 一锅法制备盐酸头孢替安酯的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425933A (en) * 1972-03-13 1976-02-25 Astra Laekemedel Ab Cephalosporins
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
US4189479A (en) * 1977-12-22 1980-02-19 Takeda Chemical Industries, Ltd. Cephalosporin esters
DE2805794A1 (de) * 1978-02-11 1979-08-16 Hoechst Ag Vorrichtung zum biologischen reinigen von abwasser
JPS6042766B2 (ja) * 1978-12-09 1985-09-25 日本化薬株式会社 基剤
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
JPS5777690A (en) * 1980-10-31 1982-05-15 Takeda Chem Ind Ltd Cephalosporin derivative
JPS58189186A (ja) * 1982-04-30 1983-11-04 Takeda Chem Ind Ltd セフアロスポリン誘導体
JPS5989691A (ja) * 1982-11-15 1984-05-23 Takeda Chem Ind Ltd セフアロスポリンエステル
US4616008A (en) * 1984-05-02 1986-10-07 Takeda Chemical Industries, Ltd. Antibacterial solid composition for oral administration

Also Published As

Publication number Publication date
ES549761A0 (es) 1987-02-16
IN158586B (da) 1986-12-13
ES8506577A1 (es) 1985-08-01
ES540839A0 (es) 1986-05-16
ATE40691T1 (de) 1989-02-15
CA1216285A (en) 1987-01-06
AU2874884A (en) 1984-12-06
DK273784A (da) 1984-12-03
GR79941B (da) 1984-10-31
KR850000455A (ko) 1985-02-27
DE3476662D1 (en) 1989-03-16
EP0128029A2 (en) 1984-12-12
AR240825A1 (es) 1991-02-28
AR245132A1 (es) 1993-12-30
NZ208281A (en) 1986-11-12
EP0128029B1 (en) 1989-02-08
ES8607317A1 (es) 1986-05-16
HU192028B (en) 1987-04-28
NO162470B (no) 1989-09-25
EP0128029A3 (en) 1985-12-18
BG60500B2 (bg) 1995-05-31
HUT34505A (en) 1985-03-28
ES8801287A1 (es) 1988-01-01
FI75574C (fi) 1988-07-11
AR240825A2 (es) 1991-02-28
HK9492A (en) 1992-01-31
ES533051A0 (es) 1985-08-01
AU566096B2 (en) 1987-10-08
NO842224L (no) 1984-12-03
FI842210A (fi) 1984-12-03
DK273784D0 (da) 1984-06-01
KR910008350B1 (ko) 1991-10-12
FI842210A0 (fi) 1984-06-01
PH19575A (en) 1986-05-26
PT78684B (en) 1986-10-21
PT78684A (en) 1984-07-01
FI75574B (fi) 1988-03-31
ES556838A0 (es) 1988-01-01
SG392G (en) 1992-03-20
MY101993A (en) 1992-02-29
US5120841A (en) 1992-06-09
ES8703480A1 (es) 1987-02-16

Similar Documents

Publication Publication Date Title
NO171853C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 7beta-(2-(tiazol-4-yl)-2-alkoksyiminoacetamido)-3-((1-pyrazolio)metyl)-3-cefem-4-karboksylat-forbindelser
NO173238C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 7-beta-(karboksyalkenoylamino)-3-cefem-4-karboksylsyre-forbindelser
NO155055C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive beta-carbolin-3-carboxylsyrederivater.
NO800858L (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 4-amino-3-kinolincarboxylsyrederivater
NO171214C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyridonkarboksylsyrederivater
NO162858C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive thiazolidinderivater.
NO155098C (no) Analogifremgangsmaate ved fremstilling av farmasoeytisk aktive aza-bicyklo-oktan-karboksylsyrer.
NO158534C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenoksyalkylkarboksylsyrederivater.
NO165841C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive heteroaryl-3-okso-propannitril-derivater.
NO167510C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenylkinolincarboxylsyrer
NO162470C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktiv ester av 7beta-(2-(2-amino-tiazol-4-yl)acetamido)-3-(((1-(2-dimetylamino-etyl)-1h-tetrazol-5-yl)tio)metyl)-cef-3-em-4-karboksylsyre.
NO162619C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive l-aminosyre-derivater
FI93458B (fi) Menetelmä terapeuttisesti käyttökelpoisen 7-/2-(2-aminotiatsol-4-yyli)-2-(Z)-hydroksi-iminoasetamido/-3-(metoksimetyyli)-3-kefeemi-4-karboksyylihappo-/ -(2,2-dimetyylipropionyylioksi)etyyli/esterin diastereomeerin I valmistamiseksi
NO930829L (no) Fremgangsmaate for fremstilling av klavulansyresalter
NO151500C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazoloksamsyre-derivater
NO168041C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive retinsyreestere av erytromycin.
IE812915L (en) ESTERS OF 7ß-SUBSTITUTED CEPH-3-EM-4-CARBOXYLIC ACIDS
NO152089C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 4-pyridon-3-karboksylsyrederivater
NO157330C (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive 3-metylflavon-8-karboksylsyreestere.
SE8500965D0 (sv) Mellanprodukter for framstellning av beta-laktamasinhibitorer
NO158673C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive azurenderivater.
NO161566C (no) Analogifremg. for fremst. av terapeutisk virksomme, antibakterielle 7-beta-(alfa-syn-metoksyimino-alfa-(2-aminotiazol-4-yl)-acet-amido)-3-((1,2,3-tiadiazol-5-yltio)metyl)-3-cefem-4 karboksylsyre og c1-c6-alkylderivater derav.
NO159532C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av 1-(4-kinolyl)-2-(4-piperidyl)-etanol eller1-(4-kinolyl)-3-(4-piperidyl)-propanol.
NO164095C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive estere av 3-(3-substituerte-amino-2-hydroksypropoksy)-4-substituerte-1,2,5-tiadiazolderivater.
DK83584D0 (da) Fremgangsmade til fremstilling af en alfa-chiral carboxylsyre eller en optisk aktiv ester deraf