NO165841C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive heteroaryl-3-okso-propannitril-derivater. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive heteroaryl-3-okso-propannitril-derivater.

Info

Publication number
NO165841C
NO165841C NO880068A NO880068A NO165841C NO 165841 C NO165841 C NO 165841C NO 880068 A NO880068 A NO 880068A NO 880068 A NO880068 A NO 880068A NO 165841 C NO165841 C NO 165841C
Authority
NO
Norway
Prior art keywords
propannitril
oxo
derivatives
preparation
therapeutically active
Prior art date
Application number
NO880068A
Other languages
English (en)
Other versions
NO880068D0 (no
NO880068L (no
NO165841B (no
Inventor
Gianfederico Doria
Anna Maria Isetta
Mario Ferrari
Domenico Trizio
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878700477A external-priority patent/GB8700477D0/en
Priority claimed from GB878717282A external-priority patent/GB8717282D0/en
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of NO880068D0 publication Critical patent/NO880068D0/no
Publication of NO880068L publication Critical patent/NO880068L/no
Publication of NO165841B publication Critical patent/NO165841B/no
Publication of NO165841C publication Critical patent/NO165841C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO880068A 1987-01-09 1988-01-08 Analogifremgangsmaate ved fremstilling av terapeutisk aktive heteroaryl-3-okso-propannitril-derivater. NO165841C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878700477A GB8700477D0 (en) 1987-01-09 1987-01-09 Heteroaryl 2-cyano-3-oxo-propanamide derivatives
GB878717282A GB8717282D0 (en) 1987-07-22 1987-07-22 Heteroaryl 3-oxo-propanenitrile derivatives

Publications (4)

Publication Number Publication Date
NO880068D0 NO880068D0 (no) 1988-01-08
NO880068L NO880068L (no) 1988-07-11
NO165841B NO165841B (no) 1991-01-07
NO165841C true NO165841C (no) 1991-04-17

Family

ID=26291768

Family Applications (1)

Application Number Title Priority Date Filing Date
NO880068A NO165841C (no) 1987-01-09 1988-01-08 Analogifremgangsmaate ved fremstilling av terapeutisk aktive heteroaryl-3-okso-propannitril-derivater.

Country Status (23)

Country Link
US (1) US4816467A (no)
EP (1) EP0274443B1 (no)
JP (1) JP2672312B2 (no)
KR (1) KR960002852B1 (no)
CN (1) CN1025500C (no)
AU (1) AU598893B2 (no)
CA (1) CA1310647C (no)
CZ (1) CZ277972B6 (no)
DE (1) DE3862937D1 (no)
DK (1) DK8088A (no)
ES (1) ES2029003T3 (no)
FI (1) FI89489C (no)
GR (1) GR3002032T3 (no)
HU (1) HU198722B (no)
IE (1) IE60620B1 (no)
IL (1) IL85004A (no)
MY (1) MY103348A (no)
NO (1) NO165841C (no)
NZ (1) NZ223113A (no)
PH (1) PH27000A (no)
PT (1) PT86516B (no)
SU (1) SU1695826A3 (no)
YU (2) YU46787B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3888864T2 (de) * 1987-04-09 1994-10-13 Du Pont Insektizide substituierte Indazole.
GB8814586D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
GB2227741B (en) * 1989-02-06 1992-08-05 Erba Carlo Spa Condensed 3-oxo-propanenitrile derivatives and process for their preparation
GB8907799D0 (en) * 1989-04-06 1989-05-17 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases
US5260328A (en) * 1989-04-06 1993-11-09 Farmitalia Carlo Erba Srl Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis
GB8916290D0 (en) * 1989-07-17 1989-08-31 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis
DE59010701D1 (de) * 1990-05-18 1997-05-22 Hoechst Ag Isoxazol-4-carbonsäureamide und hydroxyalkyliden-cyanessigsäureamide, diese verbindungen enthaltende arzneimittel und deren verwendung
US5547975A (en) * 1994-09-20 1996-08-20 Talley; John J. Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5886016A (en) * 1995-09-15 1999-03-23 G.D. Searle & Co. Benzopyranopyrazolyl derivatives for the treatment of inflammation
CZ286789B6 (en) * 1995-11-06 2000-07-12 Ortho Mcneil Pharm Inc Pyridazine derivative, process of its preparation, use and pharmaceutical preparation based thereon
GB9720899D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed heterocyclic compounds
US20020004587A1 (en) * 2000-04-11 2002-01-10 Genentech, Inc. Multivalent antibodies and uses therefor
BR0212617A (pt) * 2001-09-19 2005-02-09 Pharmacia Corp Compostos de pirazolila substituìdo para o tratamento de inflamação
AU2004263136A1 (en) * 2003-08-08 2005-02-17 Barnes-Jewish Hospital Emulsion particles for imaging and therapy and methods of use thereof
US20060035242A1 (en) 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
US20070258908A1 (en) * 2006-04-27 2007-11-08 Lanza Gregory M Detection and imaging of target tissue
CN102695710B (zh) * 2009-11-13 2015-08-19 默克雪兰诺有限公司 三环吡唑胺衍生物
CN102086212B (zh) * 2009-12-03 2013-06-12 沈阳药科大学 抗真菌剂-2，3，4，5-四氢-4H-苯并[b]噻喃并[4，3-c]吡唑-2-甲酰胺衍生物
WO2018075564A1 (en) 2016-10-17 2018-04-26 University Of Maryland, College Park Multispecific antibodies targeting human immunodeficiency virus and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268516A (en) * 1978-10-11 1981-05-19 Pfizer Inc. [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
EP0022446A1 (de) * 1979-04-06 1981-01-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Biotinestern und von Biotin
AU8029982A (en) * 1981-02-11 1982-08-19 E.I. Du Pont De Nemours And Company 3,4-dihydro-(1,4-dihydro)-2 substituted-thio benzopyrano 3,4-d imidazoles
PH21213A (en) * 1984-10-26 1987-08-21 Fujisawa Pharmaceutical Co Benzene- and pyrazole- fused heterocyclic compound and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
AU1003788A (en) 1988-07-14
KR880008987A (ko) 1988-09-13
IL85004A (en) 1991-11-21
YU1088A (en) 1989-08-31
IE60620B1 (en) 1994-07-27
CZ277972B6 (en) 1993-07-14
EP0274443B1 (en) 1991-05-29
KR960002852B1 (ko) 1996-02-27
PT86516B (pt) 1991-12-31
JP2672312B2 (ja) 1997-11-05
JPS63174988A (ja) 1988-07-19
AU598893B2 (en) 1990-07-05
US4816467A (en) 1989-03-28
CA1310647C (en) 1992-11-24
DK8088A (da) 1988-07-10
HU198722B (en) 1989-11-28
EP0274443A1 (en) 1988-07-13
YU79489A (en) 1989-10-31
HUT47113A (en) 1989-01-30
CN1025500C (zh) 1994-07-20
CZ17988A3 (en) 1993-02-17
NO880068D0 (no) 1988-01-08
FI89489C (fi) 1993-10-11
NO880068L (no) 1988-07-11
SU1695826A3 (ru) 1991-11-30
PH27000A (en) 1993-02-01
FI880078A0 (fi) 1988-01-08
FI880078A7 (fi) 1988-07-10
ES2029003T3 (es) 1992-07-16
CN88100153A (zh) 1988-07-27
DE3862937D1 (de) 1991-07-04
NO165841B (no) 1991-01-07
YU46787B (sh) 1994-06-10
FI89489B (fi) 1993-06-30
DK8088D0 (da) 1988-01-08
MY103348A (en) 1993-06-30
GR3002032T3 (en) 1992-12-30
IL85004A0 (en) 1988-06-30
IE880002L (en) 1988-07-09
NZ223113A (en) 1989-07-27
PT86516A (en) 1988-02-01

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