NO167668C - Analogifremgangsmaate til fremstilling av terapeutisk aktive epipodofyllotoksinglukosid-4'-acylderivater. - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk aktive epipodofyllotoksinglukosid-4'-acylderivater.

Info

Publication number
NO167668C
NO167668C NO885565A NO885565A NO167668C NO 167668 C NO167668 C NO 167668C NO 885565 A NO885565 A NO 885565A NO 885565 A NO885565 A NO 885565A NO 167668 C NO167668 C NO 167668C
Authority
NO
Norway
Prior art keywords
epipodophyllotoxing
lucoside
preparation
therapeutically active
acyl derivatives
Prior art date
Application number
NO885565A
Other languages
English (en)
Other versions
NO885565D0 (no
NO167668B (no
NO885565L (no
Inventor
Mark G Saulnier
Dolatrai M Vyas
David R Langley
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO885565D0 publication Critical patent/NO885565D0/no
Publication of NO885565L publication Critical patent/NO885565L/no
Publication of NO167668B publication Critical patent/NO167668B/no
Publication of NO167668C publication Critical patent/NO167668C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO885565A 1987-12-18 1988-12-15 Analogifremgangsmaate til fremstilling av terapeutisk aktive epipodofyllotoksinglukosid-4'-acylderivater. NO167668C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13512987A 1987-12-18 1987-12-18

Publications (4)

Publication Number Publication Date
NO885565D0 NO885565D0 (no) 1988-12-15
NO885565L NO885565L (no) 1989-06-19
NO167668B NO167668B (no) 1991-08-19
NO167668C true NO167668C (no) 1991-11-27

Family

ID=22466687

Family Applications (1)

Application Number Title Priority Date Filing Date
NO885565A NO167668C (no) 1987-12-18 1988-12-15 Analogifremgangsmaate til fremstilling av terapeutisk aktive epipodofyllotoksinglukosid-4'-acylderivater.

Country Status (16)

Country Link
EP (1) EP0320988A3 (no)
JP (1) JPH01279896A (no)
KR (1) KR910008799B1 (no)
CN (1) CN1033631A (no)
AU (1) AU616717B2 (no)
CA (1) CA1312074C (no)
DD (2) DD283401A5 (no)
DK (1) DK702688A (no)
FI (1) FI885785A (no)
HU (1) HU202548B (no)
MY (1) MY104067A (no)
NO (1) NO167668C (no)
NZ (1) NZ227286A (no)
PT (1) PT89253B (no)
YU (2) YU179088A (no)
ZA (2) ZA886810B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868291A (en) * 1987-08-20 1989-09-19 Bristol-Myers Company 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
FR2655047A1 (fr) * 1989-11-24 1991-05-31 Pf Medicament Derives d'etoposide, leur preparation et leur application comme intermediaires de synthese.
EP0540263A1 (en) * 1991-10-23 1993-05-05 Cancer Research Campaign Technology Limited Bacterial nitroreductase for the reduction of CB 1954 and analogues thereof to a cytotoxic form
CA2468479C (en) 2001-12-03 2010-04-27 Universitaetsklinikum Charite Der Humboldt-Universitaet Zu Berlin Technologietransferstelle Podophyllotoxins as antiproliferative agents
GB0421296D0 (en) * 2004-09-24 2004-10-27 Angiogene Pharm Ltd Bioreductively-activated prodrugs
CN104622809B (zh) * 2008-05-23 2019-04-19 英属哥伦比亚大学 用于脂质体纳米颗粒的修饰的药物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE546388A (no) *
NL6613143A (no) * 1965-09-21 1967-03-22
DE3374317D1 (en) * 1982-11-26 1987-12-10 Nippon Kayaku Kk Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
IL77334A (en) * 1985-12-16 1991-04-15 Univ Bar Ilan Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor

Also Published As

Publication number Publication date
CN1033631A (zh) 1989-07-05
EP0320988A3 (en) 1990-08-22
JPH01279896A (ja) 1989-11-10
AU2706288A (en) 1989-06-29
NO885565D0 (no) 1988-12-15
DK702688D0 (da) 1988-12-16
AU616717B2 (en) 1991-11-07
DK702688A (da) 1989-06-19
ZA889392B (en) 1989-09-27
DD283401A5 (de) 1990-10-10
ZA886810B (en) 1989-08-30
FI885785A (fi) 1989-06-19
FI885785A0 (fi) 1988-12-14
DD296082A5 (de) 1991-11-21
NO167668B (no) 1991-08-19
KR910008799B1 (ko) 1991-10-21
YU179088A (en) 1990-02-28
MY104067A (en) 1993-11-30
CA1312074C (en) 1992-12-29
KR890009965A (ko) 1989-08-05
YU228388A (sh) 1993-10-20
EP0320988A2 (en) 1989-06-21
NZ227286A (en) 1991-08-27
HU202548B (en) 1991-03-28
NO885565L (no) 1989-06-19
HUT48641A (en) 1989-06-28
PT89253B (pt) 1993-07-30
PT89253A (pt) 1989-12-29

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