PT89253A - Processo para a preparacao de derivados de 4' e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de 4' e de composicoes farmaceuticas que os contem

Info

Publication number
PT89253A
PT89253A PT89253A PT8925388A PT89253A PT 89253 A PT89253 A PT 89253A PT 89253 A PT89253 A PT 89253A PT 8925388 A PT8925388 A PT 8925388A PT 89253 A PT89253 A PT 89253A
Authority
PT
Portugal
Prior art keywords
derivatives
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
PT89253A
Other languages
English (en)
Other versions
PT89253B (pt
Inventor
Mark G Saulnier
Dolatrai M Vyas
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of PT89253A publication Critical patent/PT89253A/pt
Publication of PT89253B publication Critical patent/PT89253B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PT89253A 1987-12-18 1988-12-16 Processo para a preparacao de derivados de 4' e de composicoes farmaceuticas que os contem PT89253B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13512987A 1987-12-18 1987-12-18

Publications (2)

Publication Number Publication Date
PT89253A true PT89253A (pt) 1989-12-29
PT89253B PT89253B (pt) 1993-07-30

Family

ID=22466687

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89253A PT89253B (pt) 1987-12-18 1988-12-16 Processo para a preparacao de derivados de 4' e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
EP (1) EP0320988A3 (pt)
JP (1) JPH01279896A (pt)
KR (1) KR910008799B1 (pt)
CN (1) CN1033631A (pt)
AU (1) AU616717B2 (pt)
CA (1) CA1312074C (pt)
DD (2) DD283401A5 (pt)
DK (1) DK702688A (pt)
FI (1) FI885785A (pt)
HU (1) HU202548B (pt)
MY (1) MY104067A (pt)
NO (1) NO167668C (pt)
NZ (1) NZ227286A (pt)
PT (1) PT89253B (pt)
YU (2) YU179088A (pt)
ZA (2) ZA886810B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868291A (en) * 1987-08-20 1989-09-19 Bristol-Myers Company 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
FR2655047A1 (fr) * 1989-11-24 1991-05-31 Pf Medicament Derives d'etoposide, leur preparation et leur application comme intermediaires de synthese.
EP0540263A1 (en) * 1991-10-23 1993-05-05 Cancer Research Campaign Technology Limited Bacterial nitroreductase for the reduction of CB 1954 and analogues thereof to a cytotoxic form
CA2468479C (en) 2001-12-03 2010-04-27 Universitaetsklinikum Charite Der Humboldt-Universitaet Zu Berlin Technologietransferstelle Podophyllotoxins as antiproliferative agents
GB0421296D0 (en) * 2004-09-24 2004-10-27 Angiogene Pharm Ltd Bioreductively-activated prodrugs
CN104622809B (zh) * 2008-05-23 2019-04-19 英属哥伦比亚大学 用于脂质体纳米颗粒的修饰的药物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE546388A (pt) *
NL6613143A (pt) * 1965-09-21 1967-03-22
DE3374317D1 (en) * 1982-11-26 1987-12-10 Nippon Kayaku Kk Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
IL77334A (en) * 1985-12-16 1991-04-15 Univ Bar Ilan Synthesis of 9-epipodophyllotoxin glucoside derivatives and some novel intermediates therefor

Also Published As

Publication number Publication date
CN1033631A (zh) 1989-07-05
EP0320988A3 (en) 1990-08-22
JPH01279896A (ja) 1989-11-10
AU2706288A (en) 1989-06-29
NO885565D0 (no) 1988-12-15
DK702688D0 (da) 1988-12-16
AU616717B2 (en) 1991-11-07
DK702688A (da) 1989-06-19
ZA889392B (en) 1989-09-27
DD283401A5 (de) 1990-10-10
ZA886810B (en) 1989-08-30
FI885785A (fi) 1989-06-19
FI885785A0 (fi) 1988-12-14
DD296082A5 (de) 1991-11-21
NO167668C (no) 1991-11-27
NO167668B (no) 1991-08-19
KR910008799B1 (ko) 1991-10-21
YU179088A (en) 1990-02-28
MY104067A (en) 1993-11-30
CA1312074C (en) 1992-12-29
KR890009965A (ko) 1989-08-05
YU228388A (sh) 1993-10-20
EP0320988A2 (en) 1989-06-21
NZ227286A (en) 1991-08-27
HU202548B (en) 1991-03-28
NO885565L (no) 1989-06-19
HUT48641A (en) 1989-06-28
PT89253B (pt) 1993-07-30

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19930125

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940731