GR3002032T3 - Heteroaryl 3-oxo-propanenitrile derivatives and process for their preparation - Google Patents

Heteroaryl 3-oxo-propanenitrile derivatives and process for their preparation

Info

Publication number
GR3002032T3
GR3002032T3 GR91400684T GR910400684T GR3002032T3 GR 3002032 T3 GR3002032 T3 GR 3002032T3 GR 91400684 T GR91400684 T GR 91400684T GR 910400684 T GR910400684 T GR 910400684T GR 3002032 T3 GR3002032 T3 GR 3002032T3
Authority
GR
Greece
Prior art keywords
heteroaryl
oxo
preparation
propanenitrile derivatives
propanenitrile
Prior art date
Application number
GR91400684T
Other languages
English (en)
Inventor
Gianfederico Doria
Anna Maria Isetta
Mario Ferrari
Domenico Trizio
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878700477A external-priority patent/GB8700477D0/en
Priority claimed from GB878717282A external-priority patent/GB8717282D0/en
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of GR3002032T3 publication Critical patent/GR3002032T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
GR91400684T 1987-01-09 1991-05-30 Heteroaryl 3-oxo-propanenitrile derivatives and process for their preparation GR3002032T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878700477A GB8700477D0 (en) 1987-01-09 1987-01-09 Heteroaryl 2-cyano-3-oxo-propanamide derivatives
GB878717282A GB8717282D0 (en) 1987-07-22 1987-07-22 Heteroaryl 3-oxo-propanenitrile derivatives

Publications (1)

Publication Number Publication Date
GR3002032T3 true GR3002032T3 (en) 1992-12-30

Family

ID=26291768

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91400684T GR3002032T3 (en) 1987-01-09 1991-05-30 Heteroaryl 3-oxo-propanenitrile derivatives and process for their preparation

Country Status (23)

Country Link
US (1) US4816467A (el)
EP (1) EP0274443B1 (el)
JP (1) JP2672312B2 (el)
KR (1) KR960002852B1 (el)
CN (1) CN1025500C (el)
AU (1) AU598893B2 (el)
CA (1) CA1310647C (el)
CZ (1) CZ277972B6 (el)
DE (1) DE3862937D1 (el)
DK (1) DK8088A (el)
ES (1) ES2029003T3 (el)
FI (1) FI89489C (el)
GR (1) GR3002032T3 (el)
HU (1) HU198722B (el)
IE (1) IE60620B1 (el)
IL (1) IL85004A (el)
MY (1) MY103348A (el)
NO (1) NO165841C (el)
NZ (1) NZ223113A (el)
PH (1) PH27000A (el)
PT (1) PT86516B (el)
SU (1) SU1695826A3 (el)
YU (2) YU46787B (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0286346B1 (en) * 1987-04-09 1994-04-06 E.I. Du Pont De Nemours And Company Insecticidal substituted indazoles
GB8814586D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Tricyclic 3-oxo-propanenitrile derivatives & process for their preparation
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
GB2227741B (en) * 1989-02-06 1992-08-05 Erba Carlo Spa Condensed 3-oxo-propanenitrile derivatives and process for their preparation
GB8907799D0 (en) * 1989-04-06 1989-05-17 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in the treatment of rheumatoid arthritis and other autoimmune diseases
US5260328A (en) * 1989-04-06 1993-11-09 Farmitalia Carlo Erba Srl Phenyl-indenopurazol 3-oxo-propanamide derivatives useful in the treatment of rheumatoid arthritis
GB8916290D0 (en) * 1989-07-17 1989-08-31 Erba Carlo Spa Heteroaryl-3-oxo-propanenitrile derivatives useful in stimulating myelopoiesis
DK0527736T3 (da) * 1990-05-18 1997-10-20 Hoechst Ag Isoxazol-4-carboxylsyreamider og hydroxyalkyliden-cyanoacetamider, lægemidler indeholdende disse forbindelser og anvendelsen af disse lægemidler.
US5547975A (en) * 1994-09-20 1996-08-20 Talley; John J. Benzopyranopyrazolyl derivatives for the treatment of inflammation
US5886016A (en) * 1995-09-15 1999-03-23 G.D. Searle & Co. Benzopyranopyrazolyl derivatives for the treatment of inflammation
GB9720899D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed heterocyclic compounds
DK2857516T3 (en) * 2000-04-11 2017-08-07 Genentech Inc Multivalent antibodies and uses thereof
ES2286275T3 (es) * 2001-09-19 2007-12-01 Pharmacia Corporation Compuestos de pirazolo sustituidos para el tratamiento de la inflamacion.
CA2534426A1 (en) * 2003-08-08 2005-02-17 Barnes-Jewish Hospital Emulsion particles for imaging and therapy and methods of use thereof
US20060035242A1 (en) 2004-08-13 2006-02-16 Michelitsch Melissa D Prion-specific peptide reagents
CA2650574A1 (en) * 2006-04-27 2007-11-08 Barnes-Jewish Hospital Detection and imaging of target tissue
CA2778174C (en) * 2009-11-13 2018-02-20 Merck Serono S.A. Tricyclic pyrazol amine derivatives as pi3k inhibitors
CN102086212B (zh) * 2009-12-03 2013-06-12 沈阳药科大学 抗真菌剂-2，3，4，5-四氢-4H-苯并[b]噻喃并[4，3-c]吡唑-2-甲酰胺衍生物
WO2018075564A1 (en) 2016-10-17 2018-04-26 University Of Maryland, College Park Multispecific antibodies targeting human immunodeficiency virus and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268516A (en) * 1978-10-11 1981-05-19 Pfizer Inc. [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
EP0022446A1 (de) * 1979-04-06 1981-01-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Biotinestern und von Biotin
EP0057932A1 (en) * 1981-02-11 1982-08-18 E.I. Du Pont De Nemours And Company Antiinflammatory and/or analgesic 3,4-dihydro(or 1,4-dihydro)-2-((substituted)thiol)-(1)-benzopyrano(3,4-d)imidazoles and their corresponding sulfoxides and sulfones
PH21213A (en) * 1984-10-26 1987-08-21 Fujisawa Pharmaceutical Co Benzene- and pyrazole- fused heterocyclic compound and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
NZ223113A (en) 1989-07-27
JP2672312B2 (ja) 1997-11-05
IL85004A (en) 1991-11-21
CZ17988A3 (en) 1993-02-17
FI880078A (fi) 1988-07-10
HU198722B (en) 1989-11-28
AU1003788A (en) 1988-07-14
SU1695826A3 (ru) 1991-11-30
IL85004A0 (en) 1988-06-30
MY103348A (en) 1993-06-30
IE60620B1 (en) 1994-07-27
PT86516B (pt) 1991-12-31
KR880008987A (ko) 1988-09-13
IE880002L (en) 1988-07-09
NO880068D0 (no) 1988-01-08
NO880068L (no) 1988-07-11
PT86516A (en) 1988-02-01
HUT47113A (en) 1989-01-30
DK8088A (da) 1988-07-10
DE3862937D1 (de) 1991-07-04
YU79489A (en) 1989-10-31
PH27000A (en) 1993-02-01
FI880078A0 (fi) 1988-01-08
EP0274443A1 (en) 1988-07-13
KR960002852B1 (ko) 1996-02-27
NO165841C (no) 1991-04-17
YU46787B (sh) 1994-06-10
FI89489C (fi) 1993-10-11
YU1088A (en) 1989-08-31
CA1310647C (en) 1992-11-24
AU598893B2 (en) 1990-07-05
FI89489B (fi) 1993-06-30
NO165841B (no) 1991-01-07
CZ277972B6 (en) 1993-07-14
US4816467A (en) 1989-03-28
EP0274443B1 (en) 1991-05-29
ES2029003T3 (es) 1992-07-16
CN88100153A (zh) 1988-07-27
JPS63174988A (ja) 1988-07-19
DK8088D0 (da) 1988-01-08
CN1025500C (zh) 1994-07-20

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