NO160849C - Analogifremgangsmaate for fremstilling av terapeutisk aktivte 4-((bicykliske heterocyklyl)-metyl-og-hetero)-piperidiner. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktivte 4-((bicykliske heterocyklyl)-metyl-og-hetero)-piperidiner.Info
- Publication number
- NO160849C NO160849C NO850085A NO850085A NO160849C NO 160849 C NO160849 C NO 160849C NO 850085 A NO850085 A NO 850085A NO 850085 A NO850085 A NO 850085A NO 160849 C NO160849 C NO 160849C
- Authority
- NO
- Norway
- Prior art keywords
- bicycleic
- heterocycyl
- piperidines
- hetero
- methyl
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US56936984A | 1984-01-09 | 1984-01-09 | |
| US67113584A | 1984-11-13 | 1984-11-13 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO850085L NO850085L (no) | 1985-07-10 |
| NO160849B NO160849B (no) | 1989-02-27 |
| NO160849C true NO160849C (no) | 1989-06-07 |
Family
ID=27075046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO850085A NO160849C (no) | 1984-01-09 | 1985-01-08 | Analogifremgangsmaate for fremstilling av terapeutisk aktivte 4-((bicykliske heterocyklyl)-metyl-og-hetero)-piperidiner. |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0151826B1 (h) |
| JP (1) | JPH0768240B2 (h) |
| KR (2) | KR870001169B1 (h) |
| AU (1) | AU573673B2 (h) |
| BG (1) | BG40965A3 (h) |
| CA (1) | CA1259609A (h) |
| DE (1) | DE3486121T2 (h) |
| DK (1) | DK8985A (h) |
| ES (1) | ES8706668A1 (h) |
| FI (1) | FI83867C (h) |
| GR (1) | GR850060B (h) |
| HU (1) | HU200338B (h) |
| IE (1) | IE59707B1 (h) |
| IL (1) | IL74018A (h) |
| MA (1) | MA20323A1 (h) |
| NO (1) | NO160849C (h) |
| NZ (1) | NZ210776A (h) |
| PH (1) | PH23995A (h) |
| PT (1) | PT79809B (h) |
| RO (1) | RO90622A (h) |
| ZW (1) | ZW485A1 (h) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0144101B1 (en) * | 1983-11-30 | 1991-02-06 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines |
| US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
| CA1260474A (en) * | 1984-12-03 | 1989-09-26 | Raymond A. Stokbroekx | Benzoxazol- and benzothiazolamine derivatives |
| US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
| KR930005004B1 (ko) * | 1985-04-15 | 1993-06-11 | 쟈안센 파아마슈우티카 엔. 부이. | 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법 |
| GB8515934D0 (en) * | 1985-06-24 | 1985-07-24 | Janssen Pharmaceutica Nv | (4-piperidinomethyl and-hetero)purines |
| FR2587029B1 (fr) * | 1985-09-11 | 1987-10-30 | Synthelabo | Derives de benzimidazole, leur preparation et leur application en therapeutique |
| KR950001015B1 (ko) * | 1986-01-10 | 1995-02-07 | 닛뽕 케미화 가부시끼가이샤 | 술폭시드 유도체의 제조방법 |
| EG17993A (en) * | 1986-02-03 | 1991-08-30 | Janssen Pharmaceutica Nv | Anti-histaminic compositions containing n-heterocyclyl-4-piperidinanines |
| US4943580A (en) * | 1987-03-09 | 1990-07-24 | Janssen Pharmaceutica N.V. | Anti-histaminic benzimidazole, imidazopyridine and purine derivatives |
| NZ223654A (en) * | 1987-03-09 | 1990-03-27 | Janssen Pharmaceutica Nv | 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions |
| CA1317939C (en) * | 1987-07-01 | 1993-05-18 | Janssen Pharmaceutica Naamloze Vennootschap | ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines |
| GB8716313D0 (en) * | 1987-07-10 | 1987-08-19 | Janssen Pharmaceutica Nv | 2-(heterocyclylalkyl)imidazopyridines |
| US4908372A (en) * | 1988-10-13 | 1990-03-13 | Merrell Dow Pharmaceuticals Inc. | Antihistaminic piperidinyl benzimidazoles |
| GB8900380D0 (en) * | 1989-01-09 | 1989-03-08 | Janssen Pharmaceutica Nv | 2-aminopyrimidinone derivatives |
| PH30434A (en) * | 1989-04-07 | 1997-05-09 | Janssen Pharmaceutica Nv | Hydroxyalkylfuranyl derivatives |
| IT1229230B (it) * | 1989-05-08 | 1991-07-26 | Dompe Farmaceutici Spa | Piperidinilimidazopiridine farmacologicamente attive. |
| JP2679745B2 (ja) * | 1989-06-29 | 1997-11-19 | 明治製菓株式会社 | アゾール誘導体及びそれらを有効成分とする抗潰瘍剤 |
| US5200407A (en) * | 1989-06-29 | 1993-04-06 | Meiji Seika Kaburhiki Kaisha | Azole derivatives and anti-ulcerative composition containing same |
| CA2022451C (en) * | 1989-08-03 | 2001-01-23 | Albert Anthony Carr | Anti-psychotic piperidynl benzimidazole compounds |
| GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
| KR100190299B1 (ko) * | 1990-07-19 | 1999-06-01 | 디르크 반테 | 신규한 옥사졸릴 유도체 |
| US5217980A (en) * | 1990-07-19 | 1993-06-08 | Janssen Pharmaceutica N.V. | Oxazolyl and piperidinyl substituted benimidazolyl compounds |
| WO1992006086A1 (en) * | 1990-10-01 | 1992-04-16 | Janssen Pharmaceutica N.V. | Novel 4-piperidinylcarbonyl derivatives |
| FI932687A0 (fi) * | 1990-12-14 | 1993-06-11 | Merrell Dow Pharma | Antiallergiska foereningar |
| WO1993014083A1 (en) * | 1992-01-09 | 1993-07-22 | Janssen Pharmaceutica N.V. | Pharmaceutically active substituted benzimidazole derivatives |
| HUT71097A (en) * | 1992-02-13 | 1995-11-28 | Merrell Dow Pharma | Piperidinyl-heterocyclic derivatives, containing sulphur pharmaceutical compositions comprising them and process for their preparation |
| CA2091204C (en) * | 1992-03-11 | 1997-04-08 | Ronald J. Mattson | Antiischemic-piperazinyl and piperidinyl-cyclohexanes |
| ES2048109B1 (es) * | 1992-07-20 | 1994-12-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol. |
| DE69413523T2 (de) * | 1993-03-18 | 1999-05-12 | Merck Sharp & Dohme Ltd., Hoddesdon, Hertfordshire | Benzimidazole derivate |
| US5521183A (en) * | 1994-08-30 | 1996-05-28 | Allergan | Use of 5-HT ligands as anti-pruritic agents |
| TW429256B (en) * | 1995-12-27 | 2001-04-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(benzimidazolyl- and imidazopyridinyl)-piperidine derivatives |
| AU3408999A (en) * | 1998-03-06 | 1999-09-20 | Janssen Pharmaceutica N.V. | Glycine transport inhibitors |
| CN1239496C (zh) * | 1999-06-28 | 2006-02-01 | 詹森药业有限公司 | 呼吸系统的合胞体病毒复制抑制剂 |
| TR200500707T2 (tr) * | 1999-06-28 | 2005-04-21 | Janssen Pharmaceutica N.V. | Solunum sistemi sinsitiyal virüsünün replikasyonunu inhibe edici maddeler. |
| KR100731271B1 (ko) | 1999-06-28 | 2007-06-21 | 얀센 파마슈티카 엔.브이. | 호흡기 신시티움 바이러스 복제 억제제 |
| TWI225488B (en) * | 1999-12-21 | 2004-12-21 | Janssen Pharmaceutica Nv | Derivatives of homopiperidinyl substituted benzimidazole analogues |
| AR033517A1 (es) | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
| CA2435730C (en) * | 2001-02-24 | 2011-03-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions |
| US7030150B2 (en) | 2001-05-11 | 2006-04-18 | Trimeris, Inc. | Benzimidazole compounds and antiviral uses thereof |
| MXPA03011722A (es) | 2001-07-02 | 2004-03-19 | Aztrazeneca Ab | Derivados de piperidina utiles como moduladores de actividad de quimiocina. |
| US6530660B1 (en) | 2001-08-16 | 2003-03-11 | Contour Optik, Inc. | Eyeglass frame with a reversible arm |
| GB0120461D0 (en) | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
| GB0122503D0 (en) | 2001-09-18 | 2001-11-07 | Astrazeneca Ab | Chemical compounds |
| CA2473236A1 (en) * | 2002-01-10 | 2003-07-24 | Neurogen Corporation | Melanin concentrating hormone receptor ligands: substituted 2-(4-benzyl-piperazin-1-ylmethyl)- and 2-(4-benzyl-diazepan-1-ylmethyl)-1h-benzoimidazole analogues |
| SE0200844D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
| SE0200843D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
| US6939877B2 (en) | 2002-09-12 | 2005-09-06 | Wyeth | Antidepressant piperidine derivatives of heterocycle-fused benzodioxans |
| AU2004209522A1 (en) * | 2003-01-17 | 2004-08-19 | Gilead Palo Alto, Inc. | Substituted heterocyclic compounds useful in the treatment of cardiovascular diseases |
| SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
| KR100640783B1 (ko) | 2004-10-30 | 2006-11-01 | 주식회사 하이닉스반도체 | 노이즈를 줄일 수 있는 데이터 출력 드라이버 |
| WO2006094948A1 (en) | 2005-03-08 | 2006-09-14 | Janssen Pharmaceutica N.V. | Diaza-spiro-[4.4]-nonane derivatives as neurokinin (nk1) antagonists |
| KR20080037655A (ko) | 2005-07-21 | 2008-04-30 | 아스트라제네카 아베 | 신규 피페리딘 유도체 |
| ATE525370T1 (de) * | 2007-10-11 | 2011-10-15 | Glaxo Group Ltd | Phthalazin- und pyridoä3,4- düpyridazinverbindungen als h1-rezeptor- antagonisten |
| SI2611444T1 (sl) | 2010-09-02 | 2016-04-29 | Suven Life Sciences Limited Serene Chambers | Spojine heterociklila kot ligandi receptorja histamina H3 |
| WO2016029146A1 (en) * | 2014-08-22 | 2016-02-25 | University Of Washington | Specific inhibitors of methionyl-trna synthetase |
| KR20180034466A (ko) | 2015-07-02 | 2018-04-04 | 호리즌 오펀 엘엘씨 | Ado-저항성 시스테아민 유사체 및 그의 용도 |
| WO2017207340A1 (de) * | 2016-05-31 | 2017-12-07 | Bayer Pharma Aktiengesellschaft | Neue substituierte benzimidazole, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln |
| GB2585700A (en) | 2019-07-12 | 2021-01-20 | Hire Torque Ltd | Hydraulic torque wrench and control system for a hydraulic torque wrench |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2857391A (en) * | 1955-04-15 | 1958-10-21 | Merck & Co Inc | Aminomethylbenzimidazoles |
| GB1260857A (en) * | 1968-07-10 | 1972-01-19 | Hexachimie | IMIDAZO-3H-(4,5-b)-PYRIDINE DERIVATIVES |
| DE2334009A1 (de) * | 1973-07-04 | 1975-01-23 | Boehringer Mannheim Gmbh | Purin-derivate sowie verfahren zu ihrer herstellung |
| SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| US4219559A (en) * | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
| US4335127A (en) * | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
| US4342870A (en) * | 1980-03-28 | 1982-08-03 | Janssen Pharmaceutica N.V. | Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives |
| PL129375B1 (en) * | 1980-07-24 | 1984-05-31 | Rhone Poulenc Ind | Process for preparing novel derivatives of 2,3,6,7-tetrahydro-thiazole-/3,2-a/-pyrimidin-5-one |
| US4443451A (en) * | 1981-07-15 | 1984-04-17 | Janssen Pharmaceutica N.V. | Bicyclic pyrimidin-5-one derivatives |
| US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
| EP0144101B1 (en) * | 1983-11-30 | 1991-02-06 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines |
| US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
-
1984
- 1984-11-16 PH PH31450A patent/PH23995A/en unknown
- 1984-12-13 DE DE8484201851T patent/DE3486121T2/de not_active Expired - Fee Related
- 1984-12-13 KR KR1019840007901A patent/KR870001169B1/ko not_active Expired
- 1984-12-13 EP EP84201851A patent/EP0151826B1/en not_active Expired - Lifetime
- 1984-12-31 ES ES539281A patent/ES8706668A1/es not_active Expired
-
1985
- 1985-01-07 AU AU37364/85A patent/AU573673B2/en not_active Ceased
- 1985-01-07 CA CA000471589A patent/CA1259609A/en not_active Expired
- 1985-01-07 NZ NZ210776A patent/NZ210776A/en unknown
- 1985-01-08 RO RO85117252A patent/RO90622A/ro unknown
- 1985-01-08 IL IL74018A patent/IL74018A/xx unknown
- 1985-01-08 ZW ZW4/85A patent/ZW485A1/xx unknown
- 1985-01-08 MA MA20547A patent/MA20323A1/fr unknown
- 1985-01-08 IE IE4285A patent/IE59707B1/en not_active IP Right Cessation
- 1985-01-08 HU HU8561A patent/HU200338B/hu not_active IP Right Cessation
- 1985-01-08 DK DK8985A patent/DK8985A/da not_active Application Discontinuation
- 1985-01-08 NO NO850085A patent/NO160849C/no unknown
- 1985-01-08 FI FI850079A patent/FI83867C/fi not_active IP Right Cessation
- 1985-01-08 JP JP60000479A patent/JPH0768240B2/ja not_active Expired - Lifetime
- 1985-01-08 PT PT79809A patent/PT79809B/pt not_active IP Right Cessation
- 1985-01-09 BG BG068329A patent/BG40965A3/xx unknown
- 1985-01-09 GR GR850060A patent/GR850060B/el unknown
-
1987
- 1987-08-13 KR KR1019870008895A patent/KR900001545B1/ko not_active Expired
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