NO160516C - Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye diazabicyclo-(3,3,1)-nonaner. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye diazabicyclo-(3,3,1)-nonaner.

Info

Publication number
NO160516C
NO160516C NO833346A NO833346A NO160516C NO 160516 C NO160516 C NO 160516C NO 833346 A NO833346 A NO 833346A NO 833346 A NO833346 A NO 833346A NO 160516 C NO160516 C NO 160516C
Authority
NO
Norway
Prior art keywords
nonanes
preparation
therapeutically active
analogy procedure
diazabicyclo
Prior art date
Application number
NO833346A
Other languages
English (en)
Other versions
NO833346L (no
NO160516B (no
Inventor
Uwe Schoen
Bernd Hackmeister
Wolfgang Kehrbach
Ulrich Kuehl
Gerd Buschmann
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of NO833346L publication Critical patent/NO833346L/no
Publication of NO160516B publication Critical patent/NO160516B/no
Publication of NO160516C publication Critical patent/NO160516C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO833346A 1982-09-18 1983-09-16 Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye diazabicyclo-(3,3,1)-nonaner. NO160516C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823234697 DE3234697A1 (de) 1982-09-18 1982-09-18 Neue diazabicyclo-(3,3,1)-nonane

Publications (3)

Publication Number Publication Date
NO833346L NO833346L (no) 1984-03-19
NO160516B NO160516B (no) 1989-01-16
NO160516C true NO160516C (no) 1989-04-26

Family

ID=6173602

Family Applications (1)

Application Number Title Priority Date Filing Date
NO833346A NO160516C (no) 1982-09-18 1983-09-16 Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye diazabicyclo-(3,3,1)-nonaner.

Country Status (25)

Country Link
US (2) US4550112A (no)
EP (2) EP0250903B1 (no)
JP (2) JPS5970686A (no)
AT (2) ATE45579T1 (no)
AU (1) AU564910B2 (no)
CA (1) CA1254209A (no)
CS (1) CS389891A3 (no)
DD (1) DD213923A5 (no)
DE (3) DE3234697A1 (no)
DK (1) DK165833C (no)
ES (1) ES8405398A1 (no)
FI (1) FI76338C (no)
GE (1) GEP19960316B (no)
GR (1) GR78722B (no)
HU (1) HU191096B (no)
IE (1) IE57580B1 (no)
IL (1) IL69751A (no)
MX (1) MX9202996A (no)
NO (1) NO160516C (no)
NZ (1) NZ205627A (no)
PH (1) PH20768A (no)
PT (1) PT77344B (no)
SU (1) SU1272989A3 (no)
UA (1) UA817A1 (no)
ZA (1) ZA836185B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3529872A1 (de) * 1985-08-21 1987-02-26 Kali Chemie Pharma Gmbh Neue tetraoxoverbindungen
WO1989000158A1 (en) * 1987-07-02 1989-01-12 Pfizer Inc. Bridged-diazabicycloalkyl quinolone carboxylic acids and esters
DE3722134A1 (de) * 1987-07-04 1989-01-19 Kali Chemie Pharma Gmbh 3-sulfonyl-3,7-diazabicyclo(3,3,1)nonan- verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE4019080A1 (de) * 1990-06-15 1991-12-19 Kali Chemie Pharma Gmbh Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel
DE4139763A1 (de) * 1991-12-03 1993-06-09 Kali-Chemie Pharma Gmbh, 3000 Hannover, De Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel
DE4402933A1 (de) * 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
DE4421324A1 (de) 1994-06-17 1995-12-21 Kali Chemie Pharma Gmbh Neue 3,7-Diazabicyclo [3,3,1] nonan-Verbindungen enthaltende Arzneimittel
SE9704709D0 (sv) 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SE9902270D0 (sv) 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
US20050004113A1 (en) * 1999-06-16 2005-01-06 Astrazeneca Ab New bispidine compounds useful in the treatment of cardiac arrhythmias
US20040229900A1 (en) * 1999-06-16 2004-11-18 Astrazeneca Ab Bispidine compounds useful in the treatment of cardiac arrythmias
SE9904765D0 (sv) 1999-12-23 1999-12-23 Astra Ab Pharmaceutically-useful compounds
SE0002603D0 (sv) * 2000-07-07 2000-07-07 Astrazeneca Ab New compounds
US6808924B1 (en) 2000-07-11 2004-10-26 Claudia Lanari Mouse mammary tumor lines expressing estrogen and progesterone receptors
AR030756A1 (es) * 2000-10-02 2003-09-03 Astrazeneca Ab Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas
SE0003795D0 (sv) * 2000-10-20 2000-10-20 Astrazeneca Ab Pharmaceutically useful compounds
SE0100326D0 (sv) * 2001-02-02 2001-02-02 Astrazeneca Ab New compounds
DE10131217A1 (de) * 2001-06-28 2003-01-09 Solvay Pharm Gmbh 3-Phenyl-3,7-diazabicyclo 3,3,1 nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
TW200418468A (en) 2002-11-18 2004-10-01 Solvay Pharm Gmbh Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events
AU2004260624A1 (en) * 2003-07-21 2005-02-10 Solvay Pharmaceuticals Gmbh Use of 3,7-diazabicyclo`3, 3,1 !nonane compounds for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients
US20050054667A1 (en) * 2003-07-21 2005-03-10 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting anti-arrhythmic events in male human patients
WO2005030207A1 (en) * 2003-09-26 2005-04-07 Solvay Pharmaceuticals Gmbh Use of 3, 7-diazabicyclo (3.3.1) nonane compounds for the treatment of brugada syndrome
SE0302775D0 (sv) * 2003-10-20 2003-10-20 Astrazeneca Ab Chemical compound and assay
SE0401540D0 (sv) * 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
SE0401539D0 (sv) 2004-06-15 2004-06-15 Astrazeneca Ab New compounds
KR20080021114A (ko) * 2005-06-13 2008-03-06 아스트라제네카 아베 심부정맥의 치료를 위한 신규한 옥사비스피딘 화합물
US10399926B1 (en) 2018-08-01 2019-09-03 Divi's Laboratories Ltd. Process for the preparation of gabapentin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2428792A1 (de) * 1974-06-14 1976-01-02 Knoll Ag Neue antiarrhythmika
LU76173A1 (no) * 1976-11-11 1978-07-10
DE2658558A1 (de) * 1976-12-23 1978-06-29 Bayer Ag Diazabicyclo(3,3,1)nonane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2726571A1 (de) * 1977-06-13 1978-12-21 Basf Ag Neue bispidinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten

Also Published As

Publication number Publication date
GEP19960316B (en) 1996-06-24
JPH0670056B2 (ja) 1994-09-07
EP0103833A2 (de) 1984-03-28
PH20768A (en) 1987-04-10
ATE69817T1 (de) 1991-12-15
DE3382466D1 (de) 1992-01-09
JPS5970686A (ja) 1984-04-21
DK165833B (da) 1993-01-25
FI76338B (fi) 1988-06-30
US4742172A (en) 1988-05-03
DK165833C (da) 1993-06-21
ZA836185B (en) 1984-04-25
AU564910B2 (en) 1987-09-03
CA1254209A (en) 1989-05-16
ATE45579T1 (de) 1989-09-15
DK422583D0 (da) 1983-09-16
NO833346L (no) 1984-03-19
FI833339A0 (fi) 1983-09-19
DK422583A (da) 1984-03-19
UA817A1 (uk) 1993-12-15
EP0103833A3 (en) 1984-11-28
HU191096B (en) 1987-01-28
NO160516B (no) 1989-01-16
FI76338C (fi) 1988-10-10
EP0103833B1 (de) 1989-08-16
PT77344A (en) 1983-10-01
MX9202996A (es) 1992-07-01
DE3380409D1 (de) 1989-09-21
ES525653A0 (es) 1984-06-01
EP0250903A3 (en) 1988-03-09
US4550112A (en) 1985-10-29
IE57580B1 (en) 1993-01-13
IE832186L (en) 1984-03-18
FI833339A (fi) 1984-03-19
AU1920683A (en) 1984-03-22
EP0250903B1 (de) 1991-11-27
PT77344B (en) 1986-03-11
CS389891A3 (en) 1992-07-15
ES8405398A1 (es) 1984-06-01
CA1259998C (no) 1989-09-26
IL69751A0 (en) 1983-12-30
EP0250903A2 (de) 1988-01-07
GR78722B (no) 1984-10-02
DE3234697A1 (de) 1984-03-22
IL69751A (en) 1986-10-31
JPH05247039A (ja) 1993-09-24
DD213923A5 (de) 1984-09-26
NZ205627A (en) 1985-11-08
SU1272989A3 (ru) 1986-11-23

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Free format text: EXPIRED IN SEPTEMBER 2003