ES488565A1 - Procedimiento para la preparacion de 8-aril-5,6,7,8-tetrahi-dropirazolo (3,4-b) (1,5) diazepin-1h,4h-5,7-dionas - Google Patents

Procedimiento para la preparacion de 8-aril-5,6,7,8-tetrahi-dropirazolo (3,4-b) (1,5) diazepin-1h,4h-5,7-dionas

Info

Publication number
ES488565A1
ES488565A1 ES488565A ES488565A ES488565A1 ES 488565 A1 ES488565 A1 ES 488565A1 ES 488565 A ES488565 A ES 488565A ES 488565 A ES488565 A ES 488565A ES 488565 A1 ES488565 A1 ES 488565A1
Authority
ES
Spain
Prior art keywords
tetrahydropyrazolo
diones
aryl
diazepin
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES488565A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES488565A1 publication Critical patent/ES488565A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la preparación de 8-aril-5,6,7,8-tetrahidropirazolo (3,4-b) (1,5) diazepin-1H,4H-5,7-dionas de la fórmula **fórmula** en donde R1 y R2 son iguales o diferentes y representan átomos de hidrógeno, grupos alcohilo con 1-6 átomos de carbono, pudiendo ser uno de los radicales R1 y R2 en cada caso también un grupo bencilo o fenilo, R3 significa un átomo de hidrógeno, un grupo alcohilo con 1- 6 átomos de carbono, que está eventualmente sustituido con un grupo alcoxi con 1-6 átomos de carbono o un grupo dialcohilamino con 2 hasta 12 átomos de carbono o un grupo cicloalcohilo con 3-6 átomos de carbono
ES488565A 1979-02-20 1980-02-14 Procedimiento para la preparacion de 8-aril-5,6,7,8-tetrahi-dropirazolo (3,4-b) (1,5) diazepin-1h,4h-5,7-dionas Expired ES488565A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792906401 DE2906401A1 (de) 1979-02-20 1979-02-20 8-aryl-5,6-7,8-tetrahydropyrazolo (3,4-b)(1,5)diazepin-1h,4h-5,7-dione und verfahren zu ihrer darstellung

Publications (1)

Publication Number Publication Date
ES488565A1 true ES488565A1 (es) 1980-10-01

Family

ID=6063358

Family Applications (1)

Application Number Title Priority Date Filing Date
ES488565A Expired ES488565A1 (es) 1979-02-20 1980-02-14 Procedimiento para la preparacion de 8-aril-5,6,7,8-tetrahi-dropirazolo (3,4-b) (1,5) diazepin-1h,4h-5,7-dionas

Country Status (9)

Country Link
US (1) US4305952A (es)
EP (1) EP0014959A1 (es)
JP (1) JPS55113787A (es)
AU (1) AU5567980A (es)
DE (1) DE2906401A1 (es)
DK (1) DK71880A (es)
ES (1) ES488565A1 (es)
IL (1) IL59411A0 (es)
ZA (1) ZA80936B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3435972A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
US5198436A (en) * 1989-10-17 1993-03-30 Ellinwood Jr Everett H Intraoral dosing method of administering trifluorobenzodiazepines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984398A (en) * 1966-12-14 1976-10-05 Roussel-Uclaf 1,5-Benzodiazepine-2,4-diones
US3700657A (en) * 1971-05-18 1972-10-24 Parke Davis & Co Tetrahydropyrazolodiazepinone compounds and methods for their production
AT325052B (de) * 1972-12-07 1975-10-10 Degussa Verfahren zur herstellung von neuen 6-azabenzo-1,5-diazepinen und ihren salzen

Also Published As

Publication number Publication date
DK71880A (da) 1980-08-21
DE2906401A1 (de) 1980-09-04
IL59411A0 (en) 1980-05-30
AU5567980A (en) 1980-08-28
JPS55113787A (en) 1980-09-02
ZA80936B (en) 1981-02-25
US4305952A (en) 1981-12-15
EP0014959A1 (de) 1980-09-03

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