NO142400C - Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye benzimidazolinon-derivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye benzimidazolinon-derivater

Info

Publication number
NO142400C
NO142400C NO751735A NO751735A NO142400C NO 142400 C NO142400 C NO 142400C NO 751735 A NO751735 A NO 751735A NO 751735 A NO751735 A NO 751735A NO 142400 C NO142400 C NO 142400C
Authority
NO
Norway
Prior art keywords
derivatives
benzimidazolinon
preparation
therapeutic active
active new
Prior art date
Application number
NO751735A
Other languages
English (en)
Norwegian (no)
Other versions
NO142400B (no
NO751735L (xx
Inventor
Paul Adrian Jan Janssen
Albert H M Th Van Heertum
Jan Vandenberk
Marcel J M C Van Der Aa
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO751735L publication Critical patent/NO751735L/no
Publication of NO142400B publication Critical patent/NO142400B/no
Publication of NO142400C publication Critical patent/NO142400C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • G01N21/766Chemiluminescence; Bioluminescence of gases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/10Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using catalysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/17Nitrogen containing
    • Y10T436/173845Amine and quaternary ammonium
    • Y10T436/175383Ammonia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/17Nitrogen containing
    • Y10T436/177692Oxides of nitrogen
    • Y10T436/178459Only nitrogen dioxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
NO751735A 1974-06-21 1975-05-15 Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye benzimidazolinon-derivater NO142400C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/481,594 US3989707A (en) 1974-06-21 1974-06-21 Benzimidazolinone derivatives

Publications (3)

Publication Number Publication Date
NO751735L NO751735L (xx) 1975-12-23
NO142400B NO142400B (no) 1980-05-05
NO142400C true NO142400C (no) 1980-08-13

Family

ID=23912586

Family Applications (1)

Application Number Title Priority Date Filing Date
NO751735A NO142400C (no) 1974-06-21 1975-05-15 Analogifremgangsmaate for fremstilling av terapeutisk aktive, nye benzimidazolinon-derivater

Country Status (25)

Country Link
US (1) US3989707A (xx)
JP (1) JPS5840553B2 (xx)
AT (1) AT345833B (xx)
AU (1) AU500910B2 (xx)
BE (1) BE830403A (xx)
CA (1) CA1053235A (xx)
CH (1) CH615173A5 (xx)
CS (1) CS190480B2 (xx)
DE (1) DE2527261C2 (xx)
DK (1) DK141751B (xx)
ES (1) ES438714A1 (xx)
FI (1) FI59589C (xx)
FR (1) FR2275210A1 (xx)
GB (1) GB1505173A (xx)
HU (1) HU170435B (xx)
IE (1) IE41383B1 (xx)
IL (1) IL47529A (xx)
NL (1) NL180587C (xx)
NO (1) NO142400C (xx)
PH (1) PH13604A (xx)
PL (1) PL98220B1 (xx)
SE (2) SE416298B (xx)
SU (1) SU585811A3 (xx)
YU (1) YU159475A (xx)
ZA (1) ZA753968B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4066772A (en) * 1975-07-21 1978-01-03 Janssen Pharmaceutica N.V. 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
NZ181256A (en) * 1975-07-21 1978-04-28 Janssen Pharmaceutica Nv 1-(w-benzazol-11-ylalkyl)-piperidine derivatives and pharmaceutical compositions containing certain of these derivatives
US4076821A (en) * 1976-02-27 1978-02-28 Yoshitomi Pharmaceutical Industries, Ltd. 4,4-Diphenylcycloalkylpiperidines and psychotropic compositions thereof
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
MA19091A1 (fr) * 1980-03-10 1981-10-01 Janssen Pharmaceutica Nv Nouveaux derives de i-(4-aryl-cyclohexyl)piperidine .
US4777265A (en) * 1986-03-11 1988-10-11 Basf Aktiengesellschaft Preparation of acrylates and methacrylates
DE4107857A1 (de) * 1991-03-12 1992-09-17 Thomae Gmbh Dr K Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE69736776T2 (de) 1996-04-19 2007-01-18 Neurosearch A/S 1-(4-piperidyl)-benzimidazole mit neurotropher aktivität
JP4366532B2 (ja) * 1997-05-30 2009-11-18 萬有製薬株式会社 2−オキソイミダゾール誘導体
WO2000031061A1 (fr) * 1998-11-20 2000-06-02 Banyu Pharmaceutical Co., Ltd. Derives de 2-oxo-imidazole
US6582351B1 (en) 1999-07-21 2003-06-24 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridinone derivatives and their use as phosphodiesterase inhibitors
US7244744B2 (en) * 2001-11-01 2007-07-17 Icagen, Inc. Piperidines
EA016286B1 (ru) * 2005-09-30 2012-03-30 Глэксо Груп Лимитед Соединения, которые обладают активностью по отношению к рецепторам м, и их применения в медицине
JP5209479B2 (ja) * 2005-09-30 2013-06-12 グラクソ グループ リミテッド M1受容体にて活性を有するベンゾイミダゾロン類
US8288412B2 (en) * 2005-09-30 2012-10-16 Glaxo Group Limited Compounds which have activity at M1 receptor and their uses in medicine
GB0605784D0 (en) * 2006-03-22 2006-05-03 Glaxo Group Ltd Compounds
EP1997381A1 (en) * 2007-06-01 2008-12-03 Commissariat à l'Energie Atomique Use of a compound having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions
GB0718415D0 (en) * 2007-09-20 2007-10-31 Glaxo Group Ltd Compounds
JP2013501804A (ja) * 2009-08-12 2013-01-17 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ カテプシンs阻害剤の調製プロセス
JPWO2022260016A1 (xx) * 2021-06-07 2022-12-15

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (xx) * 1962-06-13
US3161645A (en) * 1962-12-18 1964-12-15 Res Lab Dr C Janssen N V 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds
BE659364A (xx) * 1964-02-05
US3799932A (en) * 1970-03-20 1974-03-26 Sumitomo Chemical Co Gamma-piperidinobutyrophenones
JPS5511671B2 (xx) * 1971-08-26 1980-03-26

Also Published As

Publication number Publication date
CH615173A5 (xx) 1980-01-15
GB1505173A (en) 1978-03-30
JPS5840553B2 (ja) 1983-09-06
IL47529A (en) 1978-10-31
IL47529A0 (en) 1975-08-31
SU585811A3 (ru) 1977-12-25
CA1053235A (en) 1979-04-24
FI59589B (fi) 1981-05-29
SE415298B (sv) 1980-09-22
NL7507368A (nl) 1975-12-23
FI59589C (fi) 1981-09-10
FI751462A (xx) 1975-12-22
NL180587C (nl) 1987-03-16
DK141751B (da) 1980-06-09
JPS5113780A (xx) 1976-02-03
CS190480B2 (en) 1979-05-31
PH13604A (en) 1980-08-05
DK281975A (xx) 1975-12-22
ES438714A1 (es) 1977-07-01
US3989707A (en) 1976-11-02
PL98220B1 (pl) 1978-04-29
SE7507026L (sv) 1975-12-22
HU170435B (xx) 1977-06-28
ATA476175A (de) 1978-02-15
FR2275210B1 (xx) 1978-12-22
IE41383B1 (en) 1979-12-19
BE830403A (nl) 1975-12-19
YU159475A (en) 1982-02-28
NL180587B (nl) 1986-10-16
IE41383L (en) 1975-12-21
AU500910B2 (en) 1979-06-07
FR2275210A1 (fr) 1976-01-16
AT345833B (de) 1978-10-10
DE2527261C2 (de) 1986-09-04
AU8113875A (en) 1976-11-18
SE416298B (sv) 1980-12-15
DE2527261A1 (de) 1976-01-08
NO142400B (no) 1980-05-05
ZA753968B (en) 1977-01-26
DK141751C (xx) 1980-11-03
SE7601636L (sv) 1976-02-13
NO751735L (xx) 1975-12-23

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