FI751462A - - Google Patents

Info

Publication number
FI751462A
FI751462A FI751462A FI751462A FI751462A FI 751462 A FI751462 A FI 751462A FI 751462 A FI751462 A FI 751462A FI 751462 A FI751462 A FI 751462A FI 751462 A FI751462 A FI 751462A
Authority
FI
Finland
Prior art keywords
novel
compounds
useful
acid addition
addition salts
Prior art date
Application number
FI751462A
Other languages
English (en)
Finnish (fi)
Other versions
FI59589B (fi
FI59589C (fi
Inventor
Paul Adriaan Jan Janssen
Albert H M Th Van Heertum
Jan Vandenberk
Marcel J M C Van Der Aa
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI751462A publication Critical patent/FI751462A/fi
Publication of FI59589B publication Critical patent/FI59589B/fi
Application granted granted Critical
Publication of FI59589C publication Critical patent/FI59589C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G01N21/766—Chemiluminescence; Bioluminescence of gases
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/10—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using catalysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y10T436/173845—Amine and quaternary ammonium
    • Y10T436/175383—Ammonia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y10T436/177692—Oxides of nitrogen
    • Y10T436/178459—Only nitrogen dioxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
FI751462A 1974-06-21 1975-05-19 Analogifoerfarande foer framstaellning av terapeutiskt aktiva bensimidazolinonderivat FI59589C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/481,594 US3989707A (en) 1974-06-21 1974-06-21 Benzimidazolinone derivatives
US48159474 1974-06-21

Publications (3)

Publication Number Publication Date
FI751462A true FI751462A (xx) 1975-12-22
FI59589B FI59589B (fi) 1981-05-29
FI59589C FI59589C (fi) 1981-09-10

Family

ID=23912586

Family Applications (1)

Application Number Title Priority Date Filing Date
FI751462A FI59589C (fi) 1974-06-21 1975-05-19 Analogifoerfarande foer framstaellning av terapeutiskt aktiva bensimidazolinonderivat

Country Status (25)

Country Link
US (1) US3989707A (xx)
JP (1) JPS5840553B2 (xx)
AT (1) AT345833B (xx)
AU (1) AU500910B2 (xx)
BE (1) BE830403A (xx)
CA (1) CA1053235A (xx)
CH (1) CH615173A5 (xx)
CS (1) CS190480B2 (xx)
DE (1) DE2527261C2 (xx)
DK (1) DK141751B (xx)
ES (1) ES438714A1 (xx)
FI (1) FI59589C (xx)
FR (1) FR2275210A1 (xx)
GB (1) GB1505173A (xx)
HU (1) HU170435B (xx)
IE (1) IE41383B1 (xx)
IL (1) IL47529A (xx)
NL (1) NL180587C (xx)
NO (1) NO142400C (xx)
PH (1) PH13604A (xx)
PL (1) PL98220B1 (xx)
SE (2) SE416298B (xx)
SU (1) SU585811A3 (xx)
YU (1) YU159475A (xx)
ZA (1) ZA753968B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4066772A (en) * 1975-07-21 1978-01-03 Janssen Pharmaceutica N.V. 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
NZ181256A (en) * 1975-07-21 1978-04-28 Janssen Pharmaceutica Nv 1-(w-benzazol-11-ylalkyl)-piperidine derivatives and pharmaceutical compositions containing certain of these derivatives
US4076821A (en) * 1976-02-27 1978-02-28 Yoshitomi Pharmaceutical Industries, Ltd. 4,4-Diphenylcycloalkylpiperidines and psychotropic compositions thereof
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
MA19091A1 (fr) * 1980-03-10 1981-10-01 Janssen Pharmaceutica Nv Nouveaux derives de i-(4-aryl-cyclohexyl)piperidine .
US4777265A (en) * 1986-03-11 1988-10-11 Basf Aktiengesellschaft Preparation of acrylates and methacrylates
DE4107857A1 (de) * 1991-03-12 1992-09-17 Thomae Gmbh Dr K Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE69736776T2 (de) 1996-04-19 2007-01-18 Neurosearch A/S 1-(4-piperidyl)-benzimidazole mit neurotropher aktivität
JP4366532B2 (ja) * 1997-05-30 2009-11-18 萬有製薬株式会社 ２−オキソイミダゾール誘導体
WO2000031061A1 (fr) * 1998-11-20 2000-06-02 Banyu Pharmaceutical Co., Ltd. Derives de 2-oxo-imidazole
US6582351B1 (en) 1999-07-21 2003-06-24 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridinone derivatives and their use as phosphodiesterase inhibitors
US7244744B2 (en) * 2001-11-01 2007-07-17 Icagen, Inc. Piperidines
EA016286B1 (ru) * 2005-09-30 2012-03-30 Глэксо Груп Лимитед Соединения, которые обладают активностью по отношению к рецепторам м, и их применения в медицине
JP5209479B2 (ja) * 2005-09-30 2013-06-12 グラクソ グループ リミテッド Ｍ１受容体にて活性を有するベンゾイミダゾロン類
US8288412B2 (en) * 2005-09-30 2012-10-16 Glaxo Group Limited Compounds which have activity at M1 receptor and their uses in medicine
GB0605784D0 (en) * 2006-03-22 2006-05-03 Glaxo Group Ltd Compounds
EP1997381A1 (en) * 2007-06-01 2008-12-03 Commissariat à l'Energie Atomique Use of a compound having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions
GB0718415D0 (en) * 2007-09-20 2007-10-31 Glaxo Group Ltd Compounds
JP2013501804A (ja) * 2009-08-12 2013-01-17 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ カテプシンｓ阻害剤の調製プロセス
JPWO2022260016A1 (xx) * 2021-06-07 2022-12-15

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (xx) * 1962-06-13
US3161645A (en) * 1962-12-18 1964-12-15 Res Lab Dr C Janssen N V 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds
BE659364A (xx) * 1964-02-05
US3799932A (en) * 1970-03-20 1974-03-26 Sumitomo Chemical Co Gamma-piperidinobutyrophenones
JPS5511671B2 (xx) * 1971-08-26 1980-03-26

Also Published As

Publication number Publication date
CH615173A5 (xx) 1980-01-15
GB1505173A (en) 1978-03-30
JPS5840553B2 (ja) 1983-09-06
IL47529A (en) 1978-10-31
IL47529A0 (en) 1975-08-31
SU585811A3 (ru) 1977-12-25
CA1053235A (en) 1979-04-24
FI59589B (fi) 1981-05-29
SE415298B (sv) 1980-09-22
NL7507368A (nl) 1975-12-23
FI59589C (fi) 1981-09-10
NL180587C (nl) 1987-03-16
DK141751B (da) 1980-06-09
JPS5113780A (xx) 1976-02-03
CS190480B2 (en) 1979-05-31
PH13604A (en) 1980-08-05
DK281975A (xx) 1975-12-22
ES438714A1 (es) 1977-07-01
US3989707A (en) 1976-11-02
PL98220B1 (pl) 1978-04-29
SE7507026L (sv) 1975-12-22
HU170435B (xx) 1977-06-28
ATA476175A (de) 1978-02-15
FR2275210B1 (xx) 1978-12-22
NO142400C (no) 1980-08-13
IE41383B1 (en) 1979-12-19
BE830403A (nl) 1975-12-19
YU159475A (en) 1982-02-28
NL180587B (nl) 1986-10-16
IE41383L (en) 1975-12-21
AU500910B2 (en) 1979-06-07
FR2275210A1 (fr) 1976-01-16
AT345833B (de) 1978-10-10
DE2527261C2 (de) 1986-09-04
AU8113875A (en) 1976-11-18
SE416298B (sv) 1980-12-15
DE2527261A1 (de) 1976-01-08
NO142400B (no) 1980-05-05
ZA753968B (en) 1977-01-26
DK141751C (xx) 1980-11-03
SE7601636L (sv) 1976-02-13
NO751735L (xx) 1975-12-23

Similar Documents

Publication Publication Date Title
FR2275210B1 (xx)
IL53485A0 (en) 2,3-dioxypiperazine derivatives
ES449083A1 (es) Un procedimiento para la preparacion de un compuesto de aci-do 1-alquil (inferior)-5-aroilpirrol-2-acetico halogenado.
ES446737A1 (es) Procedimiento para la preparacion de nuevos derivados de critomicina.
GB1516655A (en) 3-substituted thio-cephem-4-carboxylic acid derivatives
NL7612201A (nl) Retinezuurderivaten.
ES452200A1 (es) Un procedimiento para la preparacion de nuevos derivados de pipendina.
SE7411243L (xx)
SE420601B (sv) Pyridazonderivat for anvendning som herbicid
NL7607868A (nl) Werkwijze ter bereiding van natriumcarbonaat- peroxyde.
ZA757807B (en) Novel substituted benzene-disulfonamides as anthelmintic agents
SE411622B (sv) 2,4,6-trijod-5-metoxiacetamido-n-metylisoftalamsyraforeningar for anvendning sasom rontgenkotrastmedel
IL47655A (en) Aqueous germicidal composition
IE40364L (en) Phenothiazines.
HK26379A (en) 2,3-dioxopiperazine derivatives
IL49718A (en) 7-( -amino- -(2,3-methyenedioxy-phenyl)-acylamido)cephalosporanic acid derivatives
JPS5236626A (en) Germicidal substituted 22cyanoacetoamide derivatives
GB1517747A (en) Formylamino-s-triazine derivatives as pest-control agents
GB1517218A (en) Triazinylamidine derivatives as pest-control agents
AU502805B2 (en) Sulphur-containing carboxylaten as ep. agents
MY7400194A (en) Novel 6,7-dimethoxyquinazolinones useful as analgesic & tranquilizer agents
DK104979A (da) 2,3-dioxopiperazinderivater til anvendelse som mellemprodukte2,3-dioxopiperazinderivater til anvn r
EG11982A (en) Nitromethylene derivatives used as insecticides
IE42601L (en) Sulphamoylbenzoic acid derivatives.
DK48578A (da) 3-substituerede quinoxalin-2-carboxamid-1,4-dioxider til anvendelse som vaekstfremmende midler for dyr

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: JANSSEN PHARMACEUTICA N.V.