NL9000798A - 2-gesubstitueerde n,n'-ditrimethoxybenzoylpiperazinen, werkwijze voor het bereiden daarvan en therapeutische preparaten, die ze bevatten. - Google Patents

2-gesubstitueerde n,n'-ditrimethoxybenzoylpiperazinen, werkwijze voor het bereiden daarvan en therapeutische preparaten, die ze bevatten. Download PDF

Info

Publication number
NL9000798A
NL9000798A NL9000798A NL9000798A NL9000798A NL 9000798 A NL9000798 A NL 9000798A NL 9000798 A NL9000798 A NL 9000798A NL 9000798 A NL9000798 A NL 9000798A NL 9000798 A NL9000798 A NL 9000798A
Authority
NL
Netherlands
Prior art keywords
compound
general formula
substituted
broad
piperazine
Prior art date
Application number
NL9000798A
Other languages
English (en)
Dutch (nl)
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of NL9000798A publication Critical patent/NL9000798A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NL9000798A 1989-04-15 1990-04-05 2-gesubstitueerde n,n'-ditrimethoxybenzoylpiperazinen, werkwijze voor het bereiden daarvan en therapeutische preparaten, die ze bevatten. NL9000798A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8908587 1989-04-15
GB898908587A GB8908587D0 (en) 1989-04-15 1989-04-15 New 2-substituted n,n'-ditrimethoxybenzoyl piperazines

Publications (1)

Publication Number Publication Date
NL9000798A true NL9000798A (nl) 1990-11-01

Family

ID=10655129

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9000798A NL9000798A (nl) 1989-04-15 1990-04-05 2-gesubstitueerde n,n'-ditrimethoxybenzoylpiperazinen, werkwijze voor het bereiden daarvan en therapeutische preparaten, die ze bevatten.

Country Status (32)

Country Link
US (1) US5019576A (el)
JP (1) JP2633709B2 (el)
KR (1) KR900016178A (el)
AR (1) AR247736A1 (el)
AT (1) AT399337B (el)
AU (1) AU631334B2 (el)
BE (1) BE1007245A3 (el)
CA (1) CA2014521C (el)
CH (1) CH681301A5 (el)
DE (1) DE4011925A1 (el)
DK (1) DK91890A (el)
DZ (1) DZ1407A1 (el)
ES (1) ES2019554A6 (el)
FI (1) FI92058C (el)
FR (2) FR2645743B1 (el)
GB (2) GB8908587D0 (el)
GR (1) GR1000355B (el)
HK (1) HK95092A (el)
IE (1) IE65058B1 (el)
IN (1) IN175799B (el)
IT (1) IT1241631B (el)
LU (1) LU87719A1 (el)
MA (1) MA21805A1 (el)
NL (1) NL9000798A (el)
NO (1) NO176098C (el)
NZ (1) NZ233250A (el)
OA (1) OA09446A (el)
PT (1) PT93736B (el)
SE (1) SE505186C2 (el)
SG (1) SG92092G (el)
TN (1) TNSN90051A1 (el)
ZA (1) ZA902566B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5344830A (en) * 1992-12-10 1994-09-06 Merck & Co., Inc. N,N-diacylpiperazine tachykinin antagonists
IL111730A (en) * 1993-11-29 1998-12-06 Fujisawa Pharmaceutical Co Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them
US5883098A (en) * 1993-11-29 1999-03-16 Fujisawa Pharmaceutical Co., Ltd. Piperazine derivatives
US5610165A (en) * 1994-02-17 1997-03-11 Merck & Co., Inc. N-acylpiperidine tachykinin antagonists
US5795894A (en) * 1995-05-02 1998-08-18 Schering Corporation Piperazino derivatives as neurokinn antagonists
CN1111528C (zh) * 1995-05-02 2003-06-18 先灵公司 用作神经激肽拮抗药的哌嗪衍生物
US5892039A (en) * 1995-08-31 1999-04-06 Schering Corporation Piperazino derivatives as neurokinin antagonists
BR9610277A (pt) * 1995-08-31 1999-07-06 Schering Corp Derivados de piperazino como antagonistas de neurowuinina
US5869488A (en) * 1996-05-01 1999-02-09 Schering Corporation Piperazino derivatives as neurokinin antagonists
FR2780649B1 (fr) * 1998-07-06 2001-03-09 Univ Paris Vii Denis Diderot Derives de la piperazine pour l'inhibition de la replication du virus de l'immunodeficience humaine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1243991A (en) * 1968-06-10 1971-08-25 Ici Ltd Piperidine, morpholine and piperazine derivatives
FR2209560A1 (en) * 1972-12-07 1974-07-05 Degussa N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin
IL85700A0 (en) * 1987-03-24 1988-08-31 Takeda Chemical Industries Ltd 1,4-disubstituted piperazine compounds,their production and use
EP0318235A3 (en) * 1987-11-25 1991-05-02 Takeda Chemical Industries, Ltd. Paf antagonist, 1,4-disubstituted piperazine compounds and production thereof
FI892468A (fi) * 1988-05-23 1989-11-24 Glaxo Group Ltd Piperazinderivat.
GB8823775D0 (en) * 1988-10-11 1988-11-16 Scras New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines
GB8823776D0 (en) * 1988-10-11 1988-11-16 Scras New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
US4997836A (en) * 1988-11-11 1991-03-05 Takeda Chemical Industries, Ltd. Trisubstituted piperazine compounds, their production and use

Also Published As

Publication number Publication date
IE901314L (en) 1990-10-15
FR2645743A1 (fr) 1990-10-19
SE505186C2 (sv) 1997-07-14
JP2633709B2 (ja) 1997-07-23
FI92058C (fi) 1994-09-26
ATA86690A (de) 1994-09-15
AT399337B (de) 1995-04-25
CA2014521C (en) 1997-09-09
ES2019554A6 (es) 1991-06-16
HK95092A (en) 1992-12-04
IE65058B1 (en) 1995-10-04
DK91890A (da) 1990-10-16
GR900100270A (en) 1991-09-27
FI92058B (fi) 1994-06-15
FI901883A0 (fi) 1990-04-12
GB9007612D0 (en) 1990-05-30
DE4011925A1 (de) 1990-10-18
FR2645859B1 (fr) 1992-06-05
IT1241631B (it) 1994-01-25
NO901631L (no) 1990-10-16
IT9020020A0 (it) 1990-04-12
FR2645743B1 (fr) 1992-06-05
FR2645859A1 (fr) 1990-10-19
SE9001269L (sv) 1990-10-16
AR247736A1 (es) 1995-03-31
CA2014521A1 (en) 1990-10-15
NO176098C (no) 1995-02-01
BE1007245A3 (fr) 1995-05-02
DK91890D0 (da) 1990-04-11
CH681301A5 (el) 1993-02-26
SE9001269D0 (sv) 1990-04-06
GB8908587D0 (en) 1989-06-01
KR900016178A (ko) 1990-11-12
PT93736B (pt) 1996-09-30
IN175799B (el) 1995-08-26
JPH02292266A (ja) 1990-12-03
GB2230262B (en) 1992-02-26
SG92092G (en) 1992-12-04
AU631334B2 (en) 1992-11-19
IT9020020A1 (it) 1991-10-12
PT93736A (pt) 1990-11-20
LU87719A1 (fr) 1990-07-24
GB2230262A (en) 1990-10-17
DZ1407A1 (fr) 2004-09-13
NZ233250A (en) 1991-03-26
GR1000355B (el) 1992-06-25
AU5326190A (en) 1990-11-01
TNSN90051A1 (fr) 1991-03-05
ZA902566B (en) 1991-01-30
NO176098B (no) 1994-10-24
MA21805A1 (fr) 1990-12-31
NO901631D0 (no) 1990-04-10
US5019576A (en) 1991-05-28
OA09446A (fr) 1992-10-15

Similar Documents

Publication Publication Date Title
US5015741A (en) Nicotine analogs
FI76325C (fi) Foerfarande foer framstaellning av nya nootropiska eventuellt i 1- och/eller 4-staellning substituerade 3-substituerade piperazin-2-oner.
NL8403823A (nl) Benzoezuurderivaten.
NL9000798A (nl) 2-gesubstitueerde n,n'-ditrimethoxybenzoylpiperazinen, werkwijze voor het bereiden daarvan en therapeutische preparaten, die ze bevatten.
US5001134A (en) Piperidines, processes of preparation and medications containing them
FR2485014A1 (fr) Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments
SU1428202A3 (ru) Способ получени замещенных @ -карболинов
NL7904957A (nl) Op de 4-plaats gesubstitueerd thiazoloxamzuren en hun zouten en esters.
US5138062A (en) Nicotine analogs
US4923870A (en) 2-Carbonyl substituted N,N'-di-(trimethoxygenzoyl)piperazines, process for preparing the same and therapeutical compounds containing them
US4088653A (en) Tetrahydropyridyl derivatives
US4351838A (en) Indane derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing said derivatives
NL8801314A (nl) Nieuwe 5-methoxyalkylammoniumtetrahydrofuranen en -tetrahydrothiofenen.
FI84477C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla diazin-etenylfenyloxamsyror.
KR20000010801A (ko) 중합체용 광 안정화제로서 작용하는 신규한 입체 장애 피페리딘유도체
US4927825A (en) 2-methoxycarbonyl substituted N,N'-di-(trimethoxybenzoyl) piperazines, process for preparing the same and therapeutical compounds containing them
FR2724382A1 (fr) Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique
US4267318A (en) 1-(Diarylmethyl)-4-piperidinamine and derivatives thereof
FI65621C (fi) Foerfarande foer framstaellning av som cns-aktiva medel anvaendbara 2-(4,4-difluorfenyl-butyl)-6h-oktahydropyrazino-(1,2-c) pyrimidin-6-oner
HU209620B (en) Process for producing [(1-phenyl-pirrolidine-2-yl)-methyl]-piperazine derivatives and pharmaceutical preparations containing them
HAGLID et al. CrcH2-N3
Kornet et al. Synthesis of Novel Analgesic Agents III: 1, 2-Dialky1-4-aryl and 1, 2, 4-Trialkyl-4-aryl Piperidazines
NL8002810A (nl) Secoergolineverbindingen.
Vershilov et al. PERFLUOROACYLHYDRAZONES OF AROMATIC ALDEHYDES. SYNTHESIS AND PROPERIES
PL91755B1 (el)

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed