FR2645743B1 - Compositions therapeutiques a base de derives di-substitues des n,n(prime)-ditrimethoxybenzoyle piperazines - Google Patents
Compositions therapeutiques a base de derives di-substitues des n,n(prime)-ditrimethoxybenzoyle piperazinesInfo
- Publication number
- FR2645743B1 FR2645743B1 FR909004797A FR9004797A FR2645743B1 FR 2645743 B1 FR2645743 B1 FR 2645743B1 FR 909004797 A FR909004797 A FR 909004797A FR 9004797 A FR9004797 A FR 9004797A FR 2645743 B1 FR2645743 B1 FR 2645743B1
- Authority
- FR
- France
- Prior art keywords
- ditrimethoxybenzoyle
- piperazines
- prime
- therapeutic compositions
- substituted derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898908587A GB8908587D0 (en) | 1989-04-15 | 1989-04-15 | New 2-substituted n,n'-ditrimethoxybenzoyl piperazines |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2645743A1 FR2645743A1 (fr) | 1990-10-19 |
FR2645743B1 true FR2645743B1 (fr) | 1992-06-05 |
Family
ID=10655129
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR909004797A Expired - Fee Related FR2645743B1 (fr) | 1989-04-15 | 1990-04-13 | Compositions therapeutiques a base de derives di-substitues des n,n(prime)-ditrimethoxybenzoyle piperazines |
FR909004798A Expired - Fee Related FR2645859B1 (fr) | 1989-04-15 | 1990-04-13 | Derives di-substitues des n,n(prime)-ditrimethoxybenzoyle piperazines ainsi que leur procede de preparation |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR909004798A Expired - Fee Related FR2645859B1 (fr) | 1989-04-15 | 1990-04-13 | Derives di-substitues des n,n(prime)-ditrimethoxybenzoyle piperazines ainsi que leur procede de preparation |
Country Status (32)
Country | Link |
---|---|
US (1) | US5019576A (fr) |
JP (1) | JP2633709B2 (fr) |
KR (1) | KR900016178A (fr) |
AR (1) | AR247736A1 (fr) |
AT (1) | AT399337B (fr) |
AU (1) | AU631334B2 (fr) |
BE (1) | BE1007245A3 (fr) |
CA (1) | CA2014521C (fr) |
CH (1) | CH681301A5 (fr) |
DE (1) | DE4011925A1 (fr) |
DK (1) | DK91890A (fr) |
DZ (1) | DZ1407A1 (fr) |
ES (1) | ES2019554A6 (fr) |
FI (1) | FI92058C (fr) |
FR (2) | FR2645743B1 (fr) |
GB (2) | GB8908587D0 (fr) |
GR (1) | GR1000355B (fr) |
HK (1) | HK95092A (fr) |
IE (1) | IE65058B1 (fr) |
IN (1) | IN175799B (fr) |
IT (1) | IT1241631B (fr) |
LU (1) | LU87719A1 (fr) |
MA (1) | MA21805A1 (fr) |
NL (1) | NL9000798A (fr) |
NO (1) | NO176098C (fr) |
NZ (1) | NZ233250A (fr) |
OA (1) | OA09446A (fr) |
PT (1) | PT93736B (fr) |
SE (1) | SE505186C2 (fr) |
SG (1) | SG92092G (fr) |
TN (1) | TNSN90051A1 (fr) |
ZA (1) | ZA902566B (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5344830A (en) * | 1992-12-10 | 1994-09-06 | Merck & Co., Inc. | N,N-diacylpiperazine tachykinin antagonists |
IL111730A (en) * | 1993-11-29 | 1998-12-06 | Fujisawa Pharmaceutical Co | Piperazine derivatives, processes for their preparation and pharmaceutical preparations containing them |
US5883098A (en) * | 1993-11-29 | 1999-03-16 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine derivatives |
US5610165A (en) * | 1994-02-17 | 1997-03-11 | Merck & Co., Inc. | N-acylpiperidine tachykinin antagonists |
US5795894A (en) * | 1995-05-02 | 1998-08-18 | Schering Corporation | Piperazino derivatives as neurokinn antagonists |
KR19990008230A (ko) * | 1995-05-02 | 1999-01-25 | 덜락 노만씨 | 뉴로키닌 길항제로서의 피페라지노 유도체 |
US5892039A (en) * | 1995-08-31 | 1999-04-06 | Schering Corporation | Piperazino derivatives as neurokinin antagonists |
BR9610277A (pt) * | 1995-08-31 | 1999-07-06 | Schering Corp | Derivados de piperazino como antagonistas de neurowuinina |
US5869488A (en) * | 1996-05-01 | 1999-02-09 | Schering Corporation | Piperazino derivatives as neurokinin antagonists |
FR2780649B1 (fr) | 1998-07-06 | 2001-03-09 | Univ Paris Vii Denis Diderot | Derives de la piperazine pour l'inhibition de la replication du virus de l'immunodeficience humaine |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1243991A (en) * | 1968-06-10 | 1971-08-25 | Ici Ltd | Piperidine, morpholine and piperazine derivatives |
FR2209560A1 (en) * | 1972-12-07 | 1974-07-05 | Degussa | N-(Trialkoxyaroyl)-ethylenediamine derivs - useful as cardioactive medicaments, exhibit anti-ischaemic activity comparable to nitroglycerin |
IL85700A0 (en) * | 1987-03-24 | 1988-08-31 | Takeda Chemical Industries Ltd | 1,4-disubstituted piperazine compounds,their production and use |
EP0318235A3 (fr) * | 1987-11-25 | 1991-05-02 | Takeda Chemical Industries, Ltd. | Composés de pipérazine PAF-antagoniste 1,4-disubstitués et leur production |
PT90619B (pt) * | 1988-05-23 | 1994-10-31 | Glaxo Group Ltd | Processo para a preparacao de compostos de piperazina |
GB8823775D0 (en) * | 1988-10-11 | 1988-11-16 | Scras | New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines |
GB8823776D0 (en) * | 1988-10-11 | 1988-11-16 | Scras | New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines |
US4997836A (en) * | 1988-11-11 | 1991-03-05 | Takeda Chemical Industries, Ltd. | Trisubstituted piperazine compounds, their production and use |
-
1989
- 1989-04-15 GB GB898908587A patent/GB8908587D0/en active Pending
-
1990
- 1990-04-03 ZA ZA902566A patent/ZA902566B/xx unknown
- 1990-04-04 GB GB9007612A patent/GB2230262B/en not_active Expired - Fee Related
- 1990-04-05 NL NL9000798A patent/NL9000798A/nl not_active Application Discontinuation
- 1990-04-05 IN IN140DE1990D patent/IN175799B/en unknown
- 1990-04-06 SE SE9001269A patent/SE505186C2/sv not_active IP Right Cessation
- 1990-04-06 GR GR900100270A patent/GR1000355B/el unknown
- 1990-04-09 NZ NZ233250A patent/NZ233250A/en unknown
- 1990-04-09 US US07/506,421 patent/US5019576A/en not_active Expired - Lifetime
- 1990-04-10 AR AR90316593A patent/AR247736A1/es active
- 1990-04-10 MA MA22064A patent/MA21805A1/fr unknown
- 1990-04-10 NO NO901631A patent/NO176098C/no unknown
- 1990-04-10 LU LU87719A patent/LU87719A1/fr unknown
- 1990-04-10 CH CH1206/90A patent/CH681301A5/fr not_active IP Right Cessation
- 1990-04-11 PT PT93736A patent/PT93736B/pt not_active IP Right Cessation
- 1990-04-11 BE BE9000408A patent/BE1007245A3/fr not_active IP Right Cessation
- 1990-04-11 DZ DZ900066A patent/DZ1407A1/fr active
- 1990-04-11 ES ES9001056A patent/ES2019554A6/es not_active Expired - Fee Related
- 1990-04-11 AT AT0086690A patent/AT399337B/de not_active IP Right Cessation
- 1990-04-11 DK DK091890A patent/DK91890A/da unknown
- 1990-04-11 IE IE131490A patent/IE65058B1/en not_active IP Right Cessation
- 1990-04-12 DE DE4011925A patent/DE4011925A1/de not_active Ceased
- 1990-04-12 FI FI901883A patent/FI92058C/fi not_active IP Right Cessation
- 1990-04-12 TN TNTNSN90051A patent/TNSN90051A1/fr unknown
- 1990-04-12 IT IT20020A patent/IT1241631B/it active IP Right Grant
- 1990-04-12 CA CA002014521A patent/CA2014521C/fr not_active Expired - Fee Related
- 1990-04-12 OA OA59775A patent/OA09446A/fr unknown
- 1990-04-13 JP JP2096620A patent/JP2633709B2/ja not_active Expired - Lifetime
- 1990-04-13 FR FR909004797A patent/FR2645743B1/fr not_active Expired - Fee Related
- 1990-04-13 FR FR909004798A patent/FR2645859B1/fr not_active Expired - Fee Related
- 1990-04-14 KR KR1019900005198A patent/KR900016178A/ko not_active Application Discontinuation
- 1990-04-17 AU AU53261/90A patent/AU631334B2/en not_active Ceased
-
1992
- 1992-09-11 SG SG920/92A patent/SG92092G/en unknown
- 1992-11-26 HK HK950/92A patent/HK95092A/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |