NL8701938A - Derivaten van 2,3,4,5,6,7-hexahydro 2,7-methano 1,5-benzoxazonine (resp. 1,4-benzoxazonine), werkwijze ter bereiding ervan en medicijnen, die deze verbinding bevatten. - Google Patents

Derivaten van 2,3,4,5,6,7-hexahydro 2,7-methano 1,5-benzoxazonine (resp. 1,4-benzoxazonine), werkwijze ter bereiding ervan en medicijnen, die deze verbinding bevatten. Download PDF

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Publication number
NL8701938A
NL8701938A NL8701938A NL8701938A NL8701938A NL 8701938 A NL8701938 A NL 8701938A NL 8701938 A NL8701938 A NL 8701938A NL 8701938 A NL8701938 A NL 8701938A NL 8701938 A NL8701938 A NL 8701938A
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NL
Netherlands
Prior art keywords
general formula
hydrogen
compounds
group
alkyl group
Prior art date
Application number
NL8701938A
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English (en)
Dutch (nl)
Original Assignee
Madaus & Co Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Madaus & Co Dr filed Critical Madaus & Co Dr
Publication of NL8701938A publication Critical patent/NL8701938A/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08Bridged systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NL8701938A 1986-09-08 1987-08-18 Derivaten van 2,3,4,5,6,7-hexahydro 2,7-methano 1,5-benzoxazonine (resp. 1,4-benzoxazonine), werkwijze ter bereiding ervan en medicijnen, die deze verbinding bevatten. NL8701938A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863630539 DE3630539A1 (de) 1986-09-08 1986-09-08 Derivate von 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonin (bzw. -1,4-benzoxazonin), verfahren zu ihrer herstellung und arzneimittel, die diese verbindung enthalten
DE3630539 1986-09-08

Publications (1)

Publication Number Publication Date
NL8701938A true NL8701938A (nl) 1988-04-05

Family

ID=6309142

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8701938A NL8701938A (nl) 1986-09-08 1987-08-18 Derivaten van 2,3,4,5,6,7-hexahydro 2,7-methano 1,5-benzoxazonine (resp. 1,4-benzoxazonine), werkwijze ter bereiding ervan en medicijnen, die deze verbinding bevatten.

Country Status (29)

Country Link
US (1) US4859664A (da)
JP (1) JPS6377882A (da)
KR (1) KR910002566B1 (da)
CN (1) CN1020103C (da)
AR (1) AR243190A1 (da)
AT (1) ATA185987A (da)
AU (1) AU590443B2 (da)
BE (1) BE1002121A4 (da)
CH (1) CH675723A5 (da)
CS (1) CS621687A2 (da)
DD (1) DD275052A1 (da)
DE (1) DE3630539A1 (da)
DK (1) DK464487A (da)
ES (1) ES2013322A6 (da)
FI (1) FI88800C (da)
FR (1) FR2603587B1 (da)
GB (1) GB2194786B (da)
GR (1) GR871209B (da)
HU (1) HU203106B (da)
IL (1) IL83156A (da)
IT (1) IT1228437B (da)
NL (1) NL8701938A (da)
NO (1) NO168530C (da)
PL (1) PL154258B1 (da)
PT (1) PT85656B (da)
SE (1) SE8703343L (da)
SU (1) SU1565346A3 (da)
YU (1) YU46068B (da)
ZA (1) ZA876657B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE109483T1 (de) * 1988-06-01 1994-08-15 Smithkline Beecham Corp Alpha-adrenergische rezeptorantagonisten.
EP0344980A3 (en) * 1988-06-01 1991-05-15 Smithkline Beecham Corporation Alpha-adrenergic receptor antagonists
NZ229300A (en) * 1988-06-01 1991-04-26 Smithkline Beckman Corp Substituted-2-ethenyl-3,4,5,6-tetrahydrothieno (4,3,2-cf)(3)benzazepine derivatives and pharmaceutical compositions
US4963547A (en) * 1988-06-01 1990-10-16 Smithkline Beecham Corporation Alpha-andrenergic receptor antagonists and use thereas
US4959360A (en) * 1988-06-01 1990-09-25 Smithkline Beecham Corporation α-adrenergic receptor antagonists
DE4102103A1 (de) * 1991-01-25 1992-08-20 Bayer Ag Substituierte benzoxazepine und benzthiazepine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5248645A (en) * 1992-09-01 1993-09-28 Phillips Petroleum Company Ethylene oligomerization

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3124583A (en) * 1964-03-10 Substituted derivatives of
US3118900A (en) * 1962-01-15 1964-01-21 Abbott Lab Substituted derivatives of 3-aza-6, 7-benzo-8-oxa-5-phenylbicyclo[3.3.1]-nonane
US3401166A (en) * 1966-08-01 1968-09-10 Squibb & Sons Inc Therapeutically active benzothiazines
US3446820A (en) * 1967-04-03 1969-05-27 Rexall Drug Chemical Substituted benzoxazocines and intermediates
US3869475A (en) * 1973-04-05 1975-03-04 Yissum Res Dev Co 2,6-methano-benzoxacin compounds
JPS50106985A (da) * 1973-05-08 1975-08-22
US4100277A (en) * 1976-11-08 1978-07-11 American Home Products Corporation 4,1-Benzoxazonine derivatives and process therefor
EP0024843A1 (en) * 1979-08-09 1981-03-11 Glaxo Group Limited 3,4,5,6-Tetrahydro-2,6-methano-4 beta-amino-1-benzoxocin derivatives, process for their preparation and compositions containing them

Also Published As

Publication number Publication date
NO168530B (no) 1991-11-25
SU1565346A3 (ru) 1990-05-15
CN87106267A (zh) 1988-04-13
FI88800C (fi) 1993-07-12
PT85656A (en) 1987-10-01
GB2194786B (en) 1991-01-02
FI88800B (fi) 1993-03-31
FR2603587A1 (fr) 1988-03-11
IT1228437B (it) 1991-06-17
GB8716668D0 (en) 1987-08-19
PL267628A1 (en) 1989-06-12
JPS6377882A (ja) 1988-04-08
KR910002566B1 (ko) 1991-04-26
ZA876657B (en) 1988-03-08
SE8703343D0 (sv) 1987-08-28
HUT50180A (en) 1989-12-28
PT85656B (pt) 1990-05-31
AU590443B2 (en) 1989-11-02
KR880003945A (ko) 1988-05-31
JPH0319236B2 (da) 1991-03-14
DE3630539A1 (de) 1988-03-10
DK464487D0 (da) 1987-09-07
YU46068B (sh) 1992-12-21
CN1020103C (zh) 1993-03-17
AR243190A1 (es) 1993-07-30
ATA185987A (de) 1994-05-15
NO873727L (no) 1988-03-09
CH675723A5 (da) 1990-10-31
HU203106B (en) 1991-05-28
CS621687A2 (en) 1990-09-12
DK464487A (da) 1988-03-09
ES2013322A6 (es) 1990-05-01
FI873852A (fi) 1988-03-09
IL83156A0 (en) 1987-12-31
SE8703343L (sv) 1988-03-09
NO873727D0 (no) 1987-09-07
DD275052A1 (de) 1990-01-10
NO168530C (no) 1992-03-04
GR871209B (en) 1987-11-30
AU7816287A (en) 1988-03-10
IT8721436A0 (it) 1987-07-24
US4859664A (en) 1989-08-22
FR2603587B1 (fr) 1991-02-01
FI873852A0 (fi) 1987-09-07
BE1002121A4 (fr) 1990-07-17
IL83156A (en) 1992-12-01
PL154258B1 (en) 1991-07-31
GB2194786A (en) 1988-03-16

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