FR2603587B1 - Derives de la 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine (ou -1,4-benzoxazonine), procede pour leur preparation, medicaments les contenant et composes intermediaires - Google Patents

Derives de la 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine (ou -1,4-benzoxazonine), procede pour leur preparation, medicaments les contenant et composes intermediaires

Info

Publication number
FR2603587B1
FR2603587B1 FR878712431A FR8712431A FR2603587B1 FR 2603587 B1 FR2603587 B1 FR 2603587B1 FR 878712431 A FR878712431 A FR 878712431A FR 8712431 A FR8712431 A FR 8712431A FR 2603587 B1 FR2603587 B1 FR 2603587B1
Authority
FR
France
Prior art keywords
benzoxazonine
methano
hexahydro
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR878712431A
Other languages
English (en)
Other versions
FR2603587A1 (fr
Inventor
Friedrich Eiden
Peter Gmeiner
Jurgen Schunemann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus Holding GmbH
Original Assignee
Dr Madaus GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Madaus GmbH and Co filed Critical Dr Madaus GmbH and Co
Publication of FR2603587A1 publication Critical patent/FR2603587A1/fr
Application granted granted Critical
Publication of FR2603587B1 publication Critical patent/FR2603587B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR878712431A 1986-09-08 1987-09-08 Derives de la 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine (ou -1,4-benzoxazonine), procede pour leur preparation, medicaments les contenant et composes intermediaires Expired - Fee Related FR2603587B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863630539 DE3630539A1 (de) 1986-09-08 1986-09-08 Derivate von 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonin (bzw. -1,4-benzoxazonin), verfahren zu ihrer herstellung und arzneimittel, die diese verbindung enthalten

Publications (2)

Publication Number Publication Date
FR2603587A1 FR2603587A1 (fr) 1988-03-11
FR2603587B1 true FR2603587B1 (fr) 1991-02-01

Family

ID=6309142

Family Applications (1)

Application Number Title Priority Date Filing Date
FR878712431A Expired - Fee Related FR2603587B1 (fr) 1986-09-08 1987-09-08 Derives de la 2,3,4,5,6,7-hexahydro-2,7-methano-1,5-benzoxazonine (ou -1,4-benzoxazonine), procede pour leur preparation, medicaments les contenant et composes intermediaires

Country Status (29)

Country Link
US (1) US4859664A (fr)
JP (1) JPS6377882A (fr)
KR (1) KR910002566B1 (fr)
CN (1) CN1020103C (fr)
AR (1) AR243190A1 (fr)
AT (1) ATA185987A (fr)
AU (1) AU590443B2 (fr)
BE (1) BE1002121A4 (fr)
CH (1) CH675723A5 (fr)
CS (1) CS621687A2 (fr)
DD (1) DD275052A1 (fr)
DE (1) DE3630539A1 (fr)
DK (1) DK464487A (fr)
ES (1) ES2013322A6 (fr)
FI (1) FI88800C (fr)
FR (1) FR2603587B1 (fr)
GB (1) GB2194786B (fr)
GR (1) GR871209B (fr)
HU (1) HU203106B (fr)
IL (1) IL83156A (fr)
IT (1) IT1228437B (fr)
NL (1) NL8701938A (fr)
NO (1) NO168530C (fr)
PL (1) PL154258B1 (fr)
PT (1) PT85656B (fr)
SE (1) SE8703343L (fr)
SU (1) SU1565346A3 (fr)
YU (1) YU46068B (fr)
ZA (1) ZA876657B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1320953C (fr) * 1988-06-01 1993-08-03 John J. Lafferty Antagonistes d'.alpha.-adrenorecepteurs
US4963547A (en) * 1988-06-01 1990-10-16 Smithkline Beecham Corporation Alpha-andrenergic receptor antagonists and use thereas
CA1320486C (fr) * 1988-06-01 1993-07-20 John J. Lafferty Antagonistes de recepteur .alpha. -andrenergique
ES2057121T3 (es) * 1988-06-01 1994-10-16 Smithkline Beecham Corp Antagonistas de los receptores alfa-adrenergicos.
US4959360A (en) * 1988-06-01 1990-09-25 Smithkline Beecham Corporation α-adrenergic receptor antagonists
DE4102103A1 (de) * 1991-01-25 1992-08-20 Bayer Ag Substituierte benzoxazepine und benzthiazepine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5248645A (en) * 1992-09-01 1993-09-28 Phillips Petroleum Company Ethylene oligomerization

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3124583A (en) * 1964-03-10 Substituted derivatives of
US3118900A (en) * 1962-01-15 1964-01-21 Abbott Lab Substituted derivatives of 3-aza-6, 7-benzo-8-oxa-5-phenylbicyclo[3.3.1]-nonane
US3401166A (en) * 1966-08-01 1968-09-10 Squibb & Sons Inc Therapeutically active benzothiazines
US3446820A (en) * 1967-04-03 1969-05-27 Rexall Drug Chemical Substituted benzoxazocines and intermediates
US3869475A (en) * 1973-04-05 1975-03-04 Yissum Res Dev Co 2,6-methano-benzoxacin compounds
JPS50106985A (fr) * 1973-05-08 1975-08-22
US4100277A (en) * 1976-11-08 1978-07-11 American Home Products Corporation 4,1-Benzoxazonine derivatives and process therefor
ES8107211A1 (es) * 1979-08-09 1981-10-01 Glaxo Group Ltd Un procedimiento para la preparacion de nuevos derivados de benzoxocina.

Also Published As

Publication number Publication date
GR871209B (en) 1987-11-30
FI873852A (fi) 1988-03-09
ES2013322A6 (es) 1990-05-01
GB2194786B (en) 1991-01-02
ZA876657B (en) 1988-03-08
FI88800C (fi) 1993-07-12
DK464487D0 (da) 1987-09-07
PL267628A1 (en) 1989-06-12
FI88800B (fi) 1993-03-31
SE8703343L (sv) 1988-03-09
NO873727L (no) 1988-03-09
AU590443B2 (en) 1989-11-02
NO168530B (no) 1991-11-25
NO873727D0 (no) 1987-09-07
SE8703343D0 (sv) 1987-08-28
JPS6377882A (ja) 1988-04-08
CN1020103C (zh) 1993-03-17
BE1002121A4 (fr) 1990-07-17
YU46068B (sh) 1992-12-21
PL154258B1 (en) 1991-07-31
CH675723A5 (fr) 1990-10-31
FR2603587A1 (fr) 1988-03-11
IT1228437B (it) 1991-06-17
IL83156A (en) 1992-12-01
ATA185987A (de) 1994-05-15
GB8716668D0 (en) 1987-08-19
GB2194786A (en) 1988-03-16
HUT50180A (en) 1989-12-28
KR910002566B1 (ko) 1991-04-26
NL8701938A (nl) 1988-04-05
US4859664A (en) 1989-08-22
DE3630539A1 (de) 1988-03-10
DD275052A1 (de) 1990-01-10
SU1565346A3 (ru) 1990-05-15
AR243190A1 (es) 1993-07-30
IL83156A0 (en) 1987-12-31
PT85656A (en) 1987-10-01
CS621687A2 (en) 1990-09-12
JPH0319236B2 (fr) 1991-03-14
KR880003945A (ko) 1988-05-31
DK464487A (da) 1988-03-09
PT85656B (pt) 1990-05-31
AU7816287A (en) 1988-03-10
NO168530C (no) 1992-03-04
HU203106B (en) 1991-05-28
CN87106267A (zh) 1988-04-13
FI873852A0 (fi) 1987-09-07
IT8721436A0 (it) 1987-07-24

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TP Transmission of property
ST Notification of lapse