NL8304406A - Carbonzuuramiden en derivaten ervan, werkwijzen voor de bereiding ervan en farmaceutische preparaten, die deze verbindingen bevatten. - Google Patents

Carbonzuuramiden en derivaten ervan, werkwijzen voor de bereiding ervan en farmaceutische preparaten, die deze verbindingen bevatten. Download PDF

Info

Publication number
NL8304406A
NL8304406A NL8304406A NL8304406A NL8304406A NL 8304406 A NL8304406 A NL 8304406A NL 8304406 A NL8304406 A NL 8304406A NL 8304406 A NL8304406 A NL 8304406A NL 8304406 A NL8304406 A NL 8304406A
Authority
NL
Netherlands
Prior art keywords
formula
derivative according
group
carboxylic acid
bis
Prior art date
Application number
NL8304406A
Other languages
English (en)
Dutch (nl)
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of NL8304406A publication Critical patent/NL8304406A/nl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/57Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/59Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL8304406A 1982-12-27 1983-12-22 Carbonzuuramiden en derivaten ervan, werkwijzen voor de bereiding ervan en farmaceutische preparaten, die deze verbindingen bevatten. NL8304406A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP57226685A JPS59118750A (ja) 1982-12-27 1982-12-27 カルボン酸アミド化合物およびその誘導体
JP22668582 1982-12-27

Publications (1)

Publication Number Publication Date
NL8304406A true NL8304406A (nl) 1984-07-16

Family

ID=16849045

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8304406A NL8304406A (nl) 1982-12-27 1983-12-22 Carbonzuuramiden en derivaten ervan, werkwijzen voor de bereiding ervan en farmaceutische preparaten, die deze verbindingen bevatten.

Country Status (18)

Country Link
US (1) US4661630A (de)
JP (1) JPS59118750A (de)
KR (1) KR840007714A (de)
AU (1) AU2253183A (de)
BE (1) BE898570A (de)
CA (1) CA1202312A (de)
CH (1) CH656875A5 (de)
DE (1) DE3346814A1 (de)
DK (1) DK596083A (de)
ES (2) ES8601859A1 (de)
FR (1) FR2538386B1 (de)
GB (1) GB2133006B (de)
HU (1) HU189799B (de)
IT (1) IT1170275B (de)
NL (1) NL8304406A (de)
PH (1) PH19459A (de)
SE (1) SE8307119L (de)
ZA (1) ZA839546B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59231057A (ja) * 1983-06-14 1984-12-25 Eisai Co Ltd カルボン酸アミド化合物およびその誘導体
DE3334822A1 (de) * 1983-09-26 1985-04-04 Bayer Ag, 5090 Leverkusen Neue flammschutzmittel, ihre herstellung und ihre verwendung zur flammfestausruestung von polycarbonaten
EP1854798A3 (de) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Kondensierte heterozyklische Succinimid-Verbindungen und Analoga daraus, Modulatoren der nuklearen Hormonrezeptorfunktion
UA82827C2 (en) * 2000-12-18 2008-05-26 Inhibitors against the production and release of inflammatory cytokines
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
WO2003006424A1 (en) 2001-07-10 2003-01-23 4Sc Ag Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
DE10222895A1 (de) * 2002-05-23 2003-12-11 Bosch Gmbh Robert Hochdruckspeicher für Kraftstoffeinspritzsysteme mit integriertem Druckregelventil
TWI280876B (en) * 2002-06-05 2007-05-11 Inst Med Molecular Design Inc Therapeutic drug for diabetes
EA008622B1 (ru) * 2002-06-05 2007-06-29 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Ингибиторы ассоциированной с иммунитетом протеинкиназы
TW200410671A (en) * 2002-06-05 2004-07-01 Inst Med Molecular Design Inc Medicines for inhibiting the activation of AP-1
JP4743382B2 (ja) * 2002-06-06 2011-08-10 株式会社医薬分子設計研究所 O−置換ヒドロキシアリール誘導体
KR101054562B1 (ko) * 2002-06-06 2011-08-04 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 항알레르기약
TW200410675A (en) * 2002-06-10 2004-07-01 Inst Med Molecular Design Inc An NF-κB activation inhibitor
TW200307535A (en) * 2002-06-10 2003-12-16 Inst Med Molecular Design Inc Therapeutic agent for cancer
CA2488979A1 (en) * 2002-06-11 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Medicament for treatment of neurodegenerative diseases
KR20050074949A (ko) * 2002-11-12 2005-07-19 엔오케이 가부시키가이샤 고무형상 탄성부품
WO2004056746A1 (en) * 2002-12-23 2004-07-08 4Sc Ag Cycloalkene dicarboxylic acid compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
US7365094B2 (en) 2002-12-23 2008-04-29 4Sc Ag Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
US7247736B2 (en) * 2002-12-23 2007-07-24 4Sc Ag Method of identifying inhibitors of DHODH
WO2004056747A1 (en) * 2002-12-23 2004-07-08 4Sc Ag Dhodh-inhibitors and method for their identification
EP1541198A1 (de) * 2003-12-05 2005-06-15 4Sc Ag Cycloalkyl-Verbindungen als anti-inflammatorischen, immunomodulatorischen und antiproliferativen Mittel
EP2585054A1 (de) 2010-06-24 2013-05-01 Allergan, Inc. Derivate aus cycloalkyl- und cycloalkenyl-1,2-dicarbonsäureverbindungen mit formylpeptidrezeptor-like-1 (fprl-1)-agonistischer oder antagonistischer wirkung
UA108760C2 (uk) 2010-07-01 2015-06-10 Кальцієві солі сполуки як протизапальні, імуномодулюючі та антипроліферативні засоби
MX2020009612A (es) 2018-03-16 2020-10-07 Immunic Ag Polimorfos de sal de calcio novedosos como agentes anti-inflamatorios, inmunomoduladores y anti-proliferativos.
EP4056285A1 (de) 2021-03-12 2022-09-14 Atotech Deutschland GmbH & Co. KG Triazin-silan-verbindung und ihre verwendung als haftvermittler
EP4057782A1 (de) 2021-03-12 2022-09-14 Atotech Deutschland GmbH & Co. KG Verfahren zur erhöhung der haftfestigkeit zwischen kupfer und einem organischen material und zum reduzieren von halo und keilhohlraumbildung durch die verwendung von einer modifizierten kupferoberfläche und/oder heteroaromatische silanverbindungen

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2794811A (en) * 1954-06-03 1957-06-04 Allied Chem & Dye Corp Production of cis-cyclohexane-1, 2-dicarboxylic anhydride
US2959599A (en) * 1956-11-19 1960-11-08 Allied Chem Isomerization of cyclohexene-1, 2-dicarboxylic anhydrides
US3085096A (en) * 1961-05-31 1963-04-09 Petro Tex Chem Corp Preparation of cis-4-cyclohexene-1, 2-di-carboxylic acid anhydride
US3507904A (en) * 1966-04-01 1970-04-21 Herbert Schwartz Novel tetrahydrophthalamic acids and derivatives thereof
US3922158A (en) * 1967-12-19 1975-11-25 Ciba Geigy Ag Method for inhibiting the growth of dicotyledonous plants
CH489993A (de) * 1967-12-19 1970-05-15 Ciba Geigy Das Pflanzenwachstum regulierendes und phytocides Mittel
US3549655A (en) * 1967-12-21 1970-12-22 Dow Chemical Co N-(substituted phenyl) cyclobutanedicarboximides
US3745170A (en) * 1969-03-19 1973-07-10 Sumitomo Chemical Co Novel n-(3,5-dihalophenyl)-imide compounds
FR2059977A1 (de) * 1969-08-14 1971-06-11 Socibre
US3825594A (en) * 1970-01-20 1974-07-23 Sandoz Ag Bis(trifluoromethyl)benzamides
US3654302A (en) * 1970-01-30 1972-04-04 Herbert Schwartz Tetrahydrophthalanils
US3987056A (en) * 1973-05-07 1976-10-19 Phillips Petroleum Company Disproportionation of n-aryl-1,2,3,6-tetrahydrophthalimides
US4002460A (en) * 1974-03-13 1977-01-11 Stauffer Chemical Company Triazine-antidote compositions and methods of use for cotton
US4025505A (en) * 1975-02-04 1977-05-24 Ciba-Geigy Corporation Aromatic dicarboxamides
CH615912A5 (de) * 1975-06-18 1980-02-29 Ciba Geigy Ag
FR2369252B1 (fr) * 1976-10-29 1979-02-23 Inst Nat Rech Chimique Composes a,a-difluoroalkylbenzenes substitues et leur fabricationÿ
NL7714092A (nl) * 1976-12-22 1978-06-26 Monsanto Co Werkwijze voor het bereiden van nieuwe ftalamine- en nicotinezuren.
JPS5524127A (en) * 1978-08-08 1980-02-21 Morishita Seiyaku Kk 3,6-endomethylene-delta4-1,2,3,6-tetrahydrophtalimide derivative
US4349564A (en) * 1979-04-20 1982-09-14 Ciba-Geigy Corporation Use of 1,2-dimethyl-3-fluoro-, 1-methyl-3,3-difluoro-, and 1,2-dimethyl-3,3-difluoro-cyclobutane-1,2-dicarbonic acid 3,5-dichlorophenyl imides as plant fungicides
JPS56169669A (en) * 1980-05-30 1981-12-26 Takeda Chem Ind Ltd Hexahydroisoindole derivative, its preparation and herbicide
JPS59231057A (ja) * 1983-06-14 1984-12-25 Eisai Co Ltd カルボン酸アミド化合物およびその誘導体

Also Published As

Publication number Publication date
ES543810A0 (es) 1986-06-16
JPS59118750A (ja) 1984-07-09
FR2538386B1 (fr) 1986-04-18
JPH0136819B2 (de) 1989-08-02
GB2133006A (en) 1984-07-18
IT1170275B (it) 1987-06-03
SE8307119D0 (sv) 1983-12-22
SE8307119L (sv) 1984-06-28
ZA839546B (en) 1984-08-29
DK596083D0 (da) 1983-12-23
BE898570A (fr) 1984-06-27
GB2133006B (en) 1986-10-22
IT8324351A0 (it) 1983-12-23
HU189799B (en) 1986-07-28
FR2538386A1 (fr) 1984-06-29
ES8608486A1 (es) 1986-06-16
PH19459A (en) 1986-04-18
US4661630A (en) 1987-04-28
AU2253183A (en) 1984-07-05
DE3346814A1 (de) 1984-06-28
ES528409A0 (es) 1985-11-01
DK596083A (da) 1984-06-28
KR840007714A (ko) 1984-12-10
CH656875A5 (de) 1986-07-31
CA1202312A (en) 1986-03-25
ES8601859A1 (es) 1985-11-01
GB8333713D0 (en) 1984-01-25

Similar Documents

Publication Publication Date Title
NL8304406A (nl) Carbonzuuramiden en derivaten ervan, werkwijzen voor de bereiding ervan en farmaceutische preparaten, die deze verbindingen bevatten.
DE69637444T2 (de) Imide als PDE III, PDE IV und TNF Inhibitoren
RU2102387C1 (ru) Производные n-ацил-2,3-бензодиазепина, или их стереоизомеры, или кислые соли присоединения, обладающие биологической активностью, связанной с воздействием на центральную нервную систему, и фармакологически активная композиция на их основе
EP0506539B1 (de) Heterozyklische Alkylamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
CZ398191A3 (en) Novel 4-amino alkyl-2(3h)-indolones and pharmaceutical compositions containing them
FR2694004A1 (fr) Nouvelles 3-(Hydroxybenzylidényl)-indoline-2-ones et 3-(hydroxybenzylidényl)-indoline-2-thiones, leurs procédés de préparation, et les compositions pharmaceutiques qui les contiennent.
JPH02295924A (ja) 刺激性アミノ酸拮抗剤
EP0691339A1 (de) Amin-Derivate von 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-onen und oxazolo(4,5-b)pyridin-2(3H)-onen, ihr Herstellungsverfahren und diese enthaltende pharmazeutische Zusammensetzungen
FR2476088A2 (fr) Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
EP0353557A1 (de) Tetrahydro-1-benz-[c,d]-indol-propionsäure-sulfonamide
KR101973244B1 (ko) 신규 스파이로아이소인돌리논 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암 예방 및 치료용 조성물
EP0611766A1 (de) Polysubstituierte 2-Amidothiazole-Derivate, Verfahren zu ihrer Herstellung, pharmazeutische Zusammenstellungen die sie enthalten und ihre Anwendung für die Bereitung eines Arzneimittels
JPH05508857A (ja) 興奮性アミノ酸拮抗剤
HRP920903A2 (hr) Indenoindolovi spojevi i postupak za njihovo dobivanje
FR2722195A1 (fr) Nouveaux derives de 1,3-dihydro-2h-pyrrolo(2,3-b) pyridin-2-ones et oxazolo(4,5-b) pyridin-2(3h)-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2376876C (fr) Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
PL101396B1 (pl) Sposob wytwarzania estrow fenylowych kwasu 2-karboalkoksyaminobenzimidazolilo-5 /6/-sulfonowego
EP0243808A2 (de) Isochinolindione, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
CA1282411C (en) 1,4,5,6,7,8-hexahydroquinoline compounds
CH617188A5 (de)
EP0017578B1 (de) 5-(2-Hydroxy-3-thiopropoxy)-chromon-2-carbonsäuren, ihre Salze und Ester, Verfahren zur Herstellung und Arzneimittel
FR2608157A1 (fr) Nouveaux derives de l'azaspirodecane, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant et intermediaires
DE3300522A1 (de) 3,3-dialkyl- und 3,3-alkylen-indolinderivate, verfahren zu ihrer herstellung und pharmazeutische praeparate sie enthaltend
LU84375A1 (fr) Nouveaux derives de n"-cyano n-oxydo-1 pyridinio-4 guanidine n'-substituee utiles comme medicaments antihypertenseurs et procede de leur preparation
DE2136477A1 (de) Neue Chinolindenvate, ihre Her stellung und Verwendung

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed