NL193023C - Indolylalkaanzuurderivaat, alsmede geneesmiddel met ontstekingsremmende werking. - Google Patents
Indolylalkaanzuurderivaat, alsmede geneesmiddel met ontstekingsremmende werking. Download PDFInfo
- Publication number
- NL193023C NL193023C NL8202876A NL8202876A NL193023C NL 193023 C NL193023 C NL 193023C NL 8202876 A NL8202876 A NL 8202876A NL 8202876 A NL8202876 A NL 8202876A NL 193023 C NL193023 C NL 193023C
- Authority
- NL
- Netherlands
- Prior art keywords
- compound
- indolylalkanoic
- indomethacin
- acid derivative
- acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
- C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/10—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
- C07C67/11—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond being mineral ester groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/86—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56114371A JPS5815940A (ja) | 1981-07-23 | 1981-07-23 | ポリプレニル系化合物およびその製造方法ならびにそれを含有する医薬 |
| JP11437181 | 1981-07-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8202876A NL8202876A (nl) | 1983-02-16 |
| NL193023B NL193023B (nl) | 1998-04-01 |
| NL193023C true NL193023C (nl) | 1998-08-04 |
Family
ID=14636023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8202876A NL193023C (nl) | 1981-07-23 | 1982-07-15 | Indolylalkaanzuurderivaat, alsmede geneesmiddel met ontstekingsremmende werking. |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US4455316A (sv) |
| JP (1) | JPS5815940A (sv) |
| KR (1) | KR880001027B1 (sv) |
| CA (1) | CA1189855A (sv) |
| CH (1) | CH654574A5 (sv) |
| DE (3) | DE3226687A1 (sv) |
| ES (1) | ES514213A0 (sv) |
| FR (1) | FR2510107A1 (sv) |
| GB (1) | GB2104513B (sv) |
| NL (1) | NL193023C (sv) |
| PH (1) | PH18679A (sv) |
| SE (2) | SE452461B (sv) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI901046A0 (fi) * | 1989-03-17 | 1990-03-01 | Eisai Co Ltd | Stabilisering av polyprenylfoereningen. |
| FI96169C (sv) * | 1989-07-10 | 1996-05-27 | Eisai Co Ltd | Förfarande för framställning av en komposition som innehåller en polyprenylförening |
| US5298655A (en) * | 1991-09-27 | 1994-03-29 | Merck & Co., Inc. | Farnesyl pyrophosphate analogs |
| GB9403857D0 (en) * | 1994-03-01 | 1994-04-20 | Scotia Holdings Plc | Fatty acid derivatives |
| US7054969B1 (en) * | 1998-09-18 | 2006-05-30 | Clearspeed Technology Plc | Apparatus for use in a computer system |
| CN113880717B (zh) * | 2021-10-29 | 2022-09-13 | 中国农业大学 | 一类双酯基取代的水杨酸甲酯类似物及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3798260A (en) * | 1970-12-30 | 1974-03-19 | Mitsubishi Chem Ind | Process for producing acyloxydodecatrienes |
| JPS51113842A (en) | 1975-03-31 | 1976-10-07 | Ikeda Mohandou:Kk | Process for preparing o-(2,6-dichloroanilino)phenyl acetic acid |
| US4260551A (en) * | 1975-11-18 | 1981-04-07 | Sankyo Company Limited | Polyprenyl derivatives |
| US4192953A (en) * | 1975-11-18 | 1980-03-11 | Sankyo Company Limited | Polyprenyl derivatives |
| US4059641A (en) * | 1975-11-18 | 1977-11-22 | Sankyo Company Limited | Polyprenyl derivatives |
| JPS52131507A (en) * | 1976-04-24 | 1977-11-04 | Sankyo Co Ltd | Polyprenyl derivatives |
| DE2940373A1 (de) * | 1979-10-05 | 1981-04-23 | Troponwerke GmbH & Co KG, 5000 Köln | Lysin-(1-(p-chlorbenzoyl)-5-methoxy-2-methyl-3-indol) -acetoxy-acetate, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| JPS56113718A (en) * | 1980-01-12 | 1981-09-07 | Agency Of Ind Science & Technol | Bifunctional terpenoid, its preparation, and ulcer preventive agent comprising it |
| DE3006024C2 (de) * | 1980-02-18 | 1983-08-04 | Solvon Arzneimittel-Vertriebs- Und Lizenzgesellschaft Mbh, 85011 Burgthann | Topisches, Indomethacin enthaltendes Arzneimittel in Salbenform |
| JPS5731615A (en) * | 1980-07-31 | 1982-02-20 | Eisai Co Ltd | Remedy for skin disease with keratinization |
-
1981
- 1981-07-23 JP JP56114371A patent/JPS5815940A/ja active Granted
-
1982
- 1982-07-08 PH PH27540A patent/PH18679A/en unknown
- 1982-07-08 US US06/396,184 patent/US4455316A/en not_active Expired - Lifetime
- 1982-07-15 NL NL8202876A patent/NL193023C/nl not_active IP Right Cessation
- 1982-07-16 DE DE19823226687 patent/DE3226687A1/de active Granted
- 1982-07-16 DE DE3250048A patent/DE3250048C2/de not_active Expired - Fee Related
- 1982-07-16 DE DE3250046A patent/DE3250046C2/de not_active Expired - Fee Related
- 1982-07-16 SE SE8204367A patent/SE452461B/sv not_active IP Right Cessation
- 1982-07-19 CH CH4386/82A patent/CH654574A5/fr not_active IP Right Cessation
- 1982-07-21 ES ES514213A patent/ES514213A0/es active Granted
- 1982-07-22 CA CA000407861A patent/CA1189855A/en not_active Expired
- 1982-07-22 GB GB08221164A patent/GB2104513B/en not_active Expired
- 1982-07-23 FR FR8212911A patent/FR2510107A1/fr active Granted
- 1982-07-23 KR KR8203287A patent/KR880001027B1/ko active
-
1984
- 1984-05-14 US US06/609,664 patent/US4576963A/en not_active Expired - Lifetime
-
1986
- 1986-01-17 US US06/820,488 patent/US4709079A/en not_active Expired - Fee Related
- 1986-05-12 SE SE8602138A patent/SE468812B/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SE468812B (sv) | 1993-03-22 |
| PH18679A (en) | 1985-08-29 |
| SE8204367L (sv) | 1983-01-24 |
| ES8308827A1 (es) | 1983-08-01 |
| SE8204367D0 (sv) | 1982-07-16 |
| JPS5815940A (ja) | 1983-01-29 |
| SE452461B (sv) | 1987-11-30 |
| GB2104513B (en) | 1984-12-19 |
| CH654574A5 (fr) | 1986-02-28 |
| US4709079A (en) | 1987-11-24 |
| DE3226687A1 (de) | 1983-02-10 |
| KR840000237A (ko) | 1984-02-18 |
| NL8202876A (nl) | 1983-02-16 |
| FR2510107A1 (fr) | 1983-01-28 |
| CA1189855A (en) | 1985-07-02 |
| JPH0247463B2 (sv) | 1990-10-19 |
| NL193023B (nl) | 1998-04-01 |
| ES514213A0 (es) | 1983-08-01 |
| SE8602138L (sv) | 1986-05-12 |
| KR880001027B1 (ko) | 1988-06-15 |
| SE8602138D0 (sv) | 1986-05-12 |
| US4576963A (en) | 1986-03-18 |
| DE3250046C2 (sv) | 1992-01-02 |
| FR2510107B1 (sv) | 1985-01-25 |
| DE3226687C2 (sv) | 1993-04-08 |
| DE3250048C2 (sv) | 1993-08-05 |
| GB2104513A (en) | 1983-03-09 |
| US4455316A (en) | 1984-06-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4634795A (en) | Long-chain α,ω-di-carboxylic acids and derivatives thereof and pharmaceutical compositions containing them | |
| EP0464858A1 (en) | A lipoxygenase inhibitor | |
| NL193023C (nl) | Indolylalkaanzuurderivaat, alsmede geneesmiddel met ontstekingsremmende werking. | |
| US3766263A (en) | Substituted 2-phenoxyphenylacetic acids | |
| US4067996A (en) | Phenylacetic acid derivatives | |
| JPS6160074B2 (sv) | ||
| US4699925A (en) | Biphenylylpropionic acid derivative and pharmaceutical composition containing the same | |
| JPH0215048A (ja) | ネオペンチルエステル誘導体、その製造法およびその医薬としての使用 | |
| JPH035455A (ja) | 置換ピロリジン化合物および医薬組成物 | |
| US3932499A (en) | 2-(Substituted biphenylyl) propionic acids | |
| EP0107188B1 (en) | A pharmaceutical composition and the use thereof for the treatment of inflammation | |
| JPH02223A (ja) | フリル、フエニレンおよびチエニルロイコトリエンｂ↓４類似体 | |
| US4049829A (en) | Sulphur containing hydroxy aliphatic compounds | |
| EP0103265B1 (en) | Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same | |
| PL81176B1 (sv) | ||
| KR910004719B1 (ko) | 벤조페논의 제조방법 | |
| US4269848A (en) | 5-Substituted indan-2-carboxylic acid and functional derivatives | |
| JPS6112660A (ja) | 新規２−ピロリドン誘導体及び抗炎症剤 | |
| US4670435A (en) | 10,11-dihydro-5H-dibenzo[a,d]cycloheptadiene derivatives in a method for treating cardiac arrhythmia | |
| JPH0525866B2 (sv) | ||
| IT8222560A1 (it) | Composti di poliprenile, processo per la produzione digli stessi e medicine conpenenti i medesimi | |
| US3917842A (en) | Thiopyranopyrrolylsalicylic acids and derivatives thereof | |
| EP0160258B1 (en) | (6,11-dihydro-11-oxodibenz(bm,e)oxepinyl)pentanols, a process and intermediates for their preparation and their use as medicaments | |
| CH642257A5 (it) | Esteri di 2-(6-metossi-2-naftil)propile, processo per la loro preparazione e composizioni farmaceutiche che li contengono. | |
| NL8304070A (nl) | Alkylbenzylideenderivaten, de bereiding hiervan en de therapeutische toepassing. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A85 | Still pending on 85-01-01 | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| V1 | Lapsed because of non-payment of the annual fee |
Effective date: 20000201 |