NL192203C - Tetrahydrofuran- en tetrahydrothiofeenderivaten met werking tegen de bloedplaatjes activerende factor. - Google Patents

Tetrahydrofuran- en tetrahydrothiofeenderivaten met werking tegen de bloedplaatjes activerende factor. Download PDF

Info

Publication number
NL192203C
NL192203C NL8801315A NL8801315A NL192203C NL 192203 C NL192203 C NL 192203C NL 8801315 A NL8801315 A NL 8801315A NL 8801315 A NL8801315 A NL 8801315A NL 192203 C NL192203 C NL 192203C
Authority
NL
Netherlands
Prior art keywords
compounds
platelet
rabbits
activating factor
phenyl group
Prior art date
Application number
NL8801315A
Other languages
English (en)
Dutch (nl)
Other versions
NL8801315A (nl
NL192203B (nl
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of NL8801315A publication Critical patent/NL8801315A/nl
Publication of NL192203B publication Critical patent/NL192203B/xx
Application granted granted Critical
Publication of NL192203C publication Critical patent/NL192203C/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL8801315A 1987-05-29 1988-05-20 Tetrahydrofuran- en tetrahydrothiofeenderivaten met werking tegen de bloedplaatjes activerende factor. NL192203C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878712693A GB8712693D0 (en) 1987-05-29 1987-05-29 Tetrahydrofurans etc
GB8712693 1987-05-29

Publications (3)

Publication Number Publication Date
NL8801315A NL8801315A (nl) 1988-12-16
NL192203B NL192203B (nl) 1996-11-01
NL192203C true NL192203C (nl) 1997-03-04

Family

ID=10618139

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8801315A NL192203C (nl) 1987-05-29 1988-05-20 Tetrahydrofuran- en tetrahydrothiofeenderivaten met werking tegen de bloedplaatjes activerende factor.

Country Status (32)

Country Link
US (1) US5017588A (da)
JP (1) JPH0631228B2 (da)
KR (1) KR960005152B1 (da)
AR (1) AR243885A1 (da)
AT (1) AT395715B (da)
AU (1) AU610789B2 (da)
BE (1) BE1002146A3 (da)
CA (1) CA1317959C (da)
CH (1) CH674985A5 (da)
DE (1) DE3818106A1 (da)
DK (1) DK167532B1 (da)
ES (1) ES2009924A6 (da)
FI (1) FI89353C (da)
FR (2) FR2615735B1 (da)
GB (2) GB8712693D0 (da)
GR (1) GR1000147B (da)
HK (1) HK101790A (da)
IE (1) IE61341B1 (da)
IN (1) IN168799B (da)
IT (1) IT1219698B (da)
LU (1) LU87229A1 (da)
MA (1) MA21289A1 (da)
MY (1) MY103289A (da)
NL (1) NL192203C (da)
NO (1) NO170086C (da)
NZ (1) NZ224775A (da)
OA (1) OA08878A (da)
PT (1) PT87585B (da)
SE (1) SE466449B (da)
SG (1) SG93790G (da)
TN (1) TNSN88049A1 (da)
ZA (1) ZA883731B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8701727D0 (en) * 1987-01-27 1987-03-04 Scras Tetrahydrofuran derivatives
GB8712694D0 (en) * 1987-05-29 1987-07-01 Scras Tetrahydrofurans etc
ES2010568A6 (es) * 1988-08-04 1989-11-16 Uriach & Cia Sa J Procedimiento para la obtencion de derivados 2,5-disustituidos de tetrahidrofurano.
ES2013834A6 (es) * 1989-01-30 1990-06-01 Uriach & Cia Sa J Procedimiento para la obtencion de derivados 4-sustituidos de 2-alcoxitetrahidrofurano.
US5118708A (en) * 1989-06-23 1992-06-02 Norwich Eaton Pharmaceuticals, Inc. Use of 5-phenyl-2-furan esters, amides and ketones as neuroprotective agents
US20110097352A9 (en) * 1992-01-29 2011-04-28 Pharmexa Inc. Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions
KR100326276B1 (ko) * 1999-12-14 2002-03-08 정명식 테트라하이드로푸란 유도체, 이의 제조방법 및 이를포함하는 항진균제

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1088880A (en) * 1964-11-18 1967-10-25 Vantorex Ltd ª‡-cycloalkyleneimino-substituted esters
GB8701727D0 (en) * 1987-01-27 1987-03-04 Scras Tetrahydrofuran derivatives
GB8712694D0 (en) * 1987-05-29 1987-07-01 Scras Tetrahydrofurans etc

Also Published As

Publication number Publication date
CH674985A5 (da) 1990-08-15
MY103289A (en) 1993-05-29
KR960005152B1 (ko) 1996-04-22
GB8712693D0 (en) 1987-07-01
IT1219698B (it) 1990-05-24
ATA140788A (de) 1992-07-15
JPS649988A (en) 1989-01-13
NO882335D0 (no) 1988-05-27
DK291088A (da) 1988-11-30
MA21289A1 (fr) 1988-12-31
US5017588A (en) 1991-05-21
DK167532B1 (da) 1993-11-15
GB2205100A (en) 1988-11-30
DK291088D0 (da) 1988-05-27
NO170086B (no) 1992-06-01
KR880013928A (ko) 1988-12-22
SG93790G (en) 1991-01-18
NZ224775A (en) 1990-01-29
FI882475A0 (fi) 1988-05-26
SE466449B (sv) 1992-02-17
IT8820773A0 (it) 1988-05-27
IE881599L (en) 1988-11-29
ES2009924A6 (es) 1989-10-16
SE8801964D0 (sv) 1988-05-26
GR1000147B (el) 1991-09-27
TNSN88049A1 (fr) 1990-07-10
SE8801964L (sv) 1988-11-30
FI89353C (fi) 1993-09-27
GB2205100B (en) 1990-08-15
DE3818106A1 (de) 1988-12-15
FR2615854B1 (fr) 1990-12-28
AT395715B (de) 1993-02-25
GB8812488D0 (en) 1988-06-29
IN168799B (da) 1991-06-08
IE61341B1 (en) 1994-11-02
AR243885A1 (es) 1993-09-30
FR2615735B1 (fr) 1991-01-11
AU610789B2 (en) 1991-05-23
FI882475A (fi) 1988-11-30
PT87585B (pt) 1992-09-30
FR2615735A1 (fr) 1988-12-02
AU1672288A (en) 1988-12-01
PT87585A (pt) 1989-05-31
NO882335L (no) 1988-11-30
DE3818106C2 (da) 1993-07-01
NL8801315A (nl) 1988-12-16
NO170086C (no) 1992-09-09
CA1317959C (en) 1993-05-18
FR2615854A1 (fr) 1988-12-02
GR880100342A (en) 1989-02-23
BE1002146A3 (fr) 1990-07-31
OA08878A (fr) 1989-10-31
NL192203B (nl) 1996-11-01
FI89353B (fi) 1993-06-15
ZA883731B (en) 1989-02-22
HK101790A (en) 1990-12-14
LU87229A1 (fr) 1988-12-13
JPH0631228B2 (ja) 1994-04-27

Similar Documents

Publication Publication Date Title
Do Minh et al. Reactions of phthalaldehyde with ammonia and amines
Heaney et al. The generation of iminium ions using chlorosilanes and their reactions with electron rich aromatic heterocycles
JPH04338386A (ja) ベンゾジオキソール、ベンゾジオキサンおよびベンゾジオキセピン誘導体
NL192203C (nl) Tetrahydrofuran- en tetrahydrothiofeenderivaten met werking tegen de bloedplaatjes activerende factor.
Martins et al. Haloacetylated enol ethers. 6 [5]. Synthesis of 4, 5‐trimethylene‐4, 5‐dihydroisoxazoles
FR2656610A1 (fr) Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique.
FI92195B (fi) Menetelmä terapeuttisesti käyttökelpoisten pyridiinijohdannaisten valmistamiseksi
FR2566404A1 (fr) Nouveaux derives de la 1,4-dihydropyridine, leurs sels, procede pour les preparer, et compositions pharmaceutiques les contenant
NL192520C (nl) Gesubstitueerde tetrahydrofuranderivaten met anti-PAF-werking, werkwijze voor hun bereiding en farmaceutische preparaten die hen bevat.
Katritzky et al. Aminoalkylbenzotriazoles: reagents for the aminoalkylation of electron rich heterocycles
JPH01165554A (ja) 置換ヒドロキシルアミン
NL192573C (nl) 2,5-Digesubstitueerde tetrahydrofuran- of tetrahydrothiofeenverbindingen met werking tegen de bloedplaatjesactiverende factor en farmaceutisch preparaat dat deze verbindingen bevat.
EP0312040B1 (en) 2,4-disubstituted derivatives of tetrahydrofuran
CA1193604A (en) Substituted pyridines
Carceller et al. 4-Substituted 2-alkoxytetrahydrofurans as potent and long-lasting PAF antagonists
IE47903B1 (en) Polysubstituted-2-(3-loweralkylamino-2-r o-propoxy) pyridines,process for preparing the same,and pharmaceutical compositions containing the same
Mueller-Uri et al. Synthesis of alkyl-substituted arecoline derivatives as. gamma.-aminobutyric acid uptake inhibitors
Keuper et al. Synthesis and Characterization of Novel Pyridines and 3, 3′‐Bridged Bipyridines Using 1, x‐Cyclohexanediones
RU2060252C1 (ru) ПРОИЗВОДНЫЕ N-(2,4- ИЛИ 2,5-ДИЗАМЕЩЕННОГО ТЕТРАГИДРОФУРИЛАЛКИЛ)-N-(ФЕНИЛЭТИЛ- β -ОЛ)АМИНА В РАЦЕМИЧЕСКОЙ ИЛИ ЭНАНТИОМЕРНОЙ ФОРМЕ, ИЛИ ИХ ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМАЯ СОЛЬ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ
NZ228087A (en) Imidazolinone derivatives; pharmaceutical compositions and preparatory processes
Katritzky et al. Chemistry of α‐(benzotriazol‐l‐yl) alkylpyridines. Unusual nucleophilic attack at c‐3a of the benzotriazolyl ring
Wanner et al. Synthesis of the Cyclostellettamines A− F and Related Bis (3‐alkylpyridinium) Macrocycles
NL8103710A (nl) Heteroprostaglandine-derivaten en werkwijze voor de bereiding daarvan.
US3277090A (en) 1:4-benzodioxan derivatives
FR2637592A1 (fr) Nouveaux derives de la methoxycarbonyl-2 n,n(prime)-di-(trimethoxybenzoyle) piperazine, ainsi que leur procede de preparation

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V1 Lapsed because of non-payment of the annual fee

Effective date: 20021201