NL187022C - Rifamycine derivaten met anti-bacteriele werking, en dergelijke derivaten bevattend farmaceutisch preparaat. - Google Patents
Rifamycine derivaten met anti-bacteriele werking, en dergelijke derivaten bevattend farmaceutisch preparaat.Info
- Publication number
- NL187022C NL187022C NLAANVRAGE8102290,A NL8102290A NL187022C NL 187022 C NL187022 C NL 187022C NL 8102290 A NL8102290 A NL 8102290A NL 187022 C NL187022 C NL 187022C
- Authority
- NL
- Netherlands
- Prior art keywords
- derivatives
- pharmaceutical preparation
- containing pharmaceutical
- bacterial action
- rifamycin
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- HJYYPODYNSCCOU-ODRIEIDWSA-N rifamycin SV Chemical class OC1=C(C(O)=C2C)C3=C(O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O HJYYPODYNSCCOU-ODRIEIDWSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT342980 | 1980-05-22 | ||
IT03429/80A IT1154655B (it) | 1980-05-22 | 1980-05-22 | Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica |
Publications (3)
Publication Number | Publication Date |
---|---|
NL8102290A NL8102290A (nl) | 1981-12-16 |
NL187022B NL187022B (nl) | 1990-12-03 |
NL187022C true NL187022C (nl) | 1991-05-01 |
Family
ID=11107198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NLAANVRAGE8102290,A NL187022C (nl) | 1980-05-22 | 1981-05-11 | Rifamycine derivaten met anti-bacteriele werking, en dergelijke derivaten bevattend farmaceutisch preparaat. |
Country Status (25)
Country | Link |
---|---|
US (1) | US4341785A (en, 2012) |
JP (1) | JPS5711987A (en, 2012) |
AR (1) | AR226212A1 (en, 2012) |
AT (1) | AT373599B (en, 2012) |
AU (1) | AU537093B2 (en, 2012) |
BE (1) | BE888895A (en, 2012) |
CA (1) | CA1142518A (en, 2012) |
CH (1) | CH648037A5 (en, 2012) |
DE (1) | DE3120460A1 (en, 2012) |
DK (1) | DK157876C (en, 2012) |
EG (1) | EG14891A (en, 2012) |
ES (1) | ES502906A0 (en, 2012) |
FI (1) | FI69467C (en, 2012) |
FR (1) | FR2482967A1 (en, 2012) |
GB (1) | GB2079270B (en, 2012) |
GR (1) | GR75640B (en, 2012) |
IE (1) | IE51204B1 (en, 2012) |
IT (1) | IT1154655B (en, 2012) |
LU (1) | LU83376A1 (en, 2012) |
NL (1) | NL187022C (en, 2012) |
NO (1) | NO155622C (en, 2012) |
PH (2) | PH17207A (en, 2012) |
PT (1) | PT73064B (en, 2012) |
SE (1) | SE453089B (en, 2012) |
ZA (1) | ZA813430B (en, 2012) |
Families Citing this family (77)
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IT1199374B (it) | 1984-05-15 | 1988-12-30 | Alfa Farmaceutici Spa | Processo per la preparazione di pirido-imidazo-rifamicine |
IT1264494B1 (it) * | 1993-03-23 | 1996-09-24 | Alfa Wassermann Spa | Uso di rifaximin e di formulazioni che la contengono nel trattamento delle dispepsie gastriche originate da helicobacter |
US6861053B1 (en) * | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
US5981522A (en) * | 1995-09-01 | 1999-11-09 | Kaneka Corporation | Treatment of disease caused by infection of Helicobacter |
EP0861660B9 (en) * | 1997-02-28 | 2006-06-28 | Kaneka Corporation | Curative medicine for disease caused by infection of Helicobacter |
US7122525B2 (en) * | 2001-11-21 | 2006-10-17 | Activbiotics, Inc. | Targeted therapeutics and uses thereof |
WO2003051299A2 (en) * | 2001-12-13 | 2003-06-26 | Activbiotics, Inc. | Sulfhydryl rifamycins and uses thereof |
ATE552824T1 (de) * | 2002-11-05 | 2012-04-15 | Fadim S R L | Kontrollierte und kontinuierliche verabreichung von rifaximin |
US7820652B2 (en) * | 2003-09-24 | 2010-10-26 | Activbiotics Pharma, Llc | Regimen for the administration of rifamycin-class antibiotics |
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US7906542B2 (en) * | 2004-11-04 | 2011-03-15 | Alfa Wassermann, S.P.A. | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin |
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US7256187B2 (en) * | 2004-03-10 | 2007-08-14 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime derivatives effective against drug-resistant microbes |
US7265107B2 (en) * | 2004-03-10 | 2007-09-04 | Cumbre Pharmaceuticals Inc. | Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes |
US7202246B2 (en) * | 2004-06-09 | 2007-04-10 | Cumbre Pharmaceuticals Inc. | Spiro-rifamycin derivatives targeting RNA polymerase |
US20060210483A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections |
US20060210492A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Use of rifaximin for treatment and prevention of periodontal conditions |
US8003118B2 (en) * | 2005-03-02 | 2011-08-23 | Kodsi Robert E | Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis |
EP1698630B1 (en) | 2005-03-03 | 2014-09-03 | ALFA WASSERMANN S.p.A. | New polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations |
ITBO20050123A1 (it) * | 2005-03-07 | 2005-06-06 | Alfa Wassermann Spa | Formulazioni farmaceutiche gastroresistenti contenenti rifaximina |
KR101327635B1 (ko) | 2005-08-11 | 2013-11-12 | 타간타 테라퓨틱스 인크. | 포스폰산화 리파마이신, 및 그의 뼈 및 관절 감염의 저지및 치료 용도 |
MX2008011305A (es) | 2006-03-09 | 2009-02-10 | Salix Pharmaceuticals Inc | Preparacion anti-disfunsion rectal con rifaximina. |
EP2054066B1 (en) | 2006-08-02 | 2015-04-15 | Salix Pharmaceuticals, Inc. | Methods for treatment of radiation enteritis |
ITMI20061692A1 (it) | 2006-09-05 | 2008-03-06 | Alfa Wassermann Spa | Uso di polioli per ottenere forme polimorfe stabili di rifaximina |
CA2663776C (en) * | 2006-09-22 | 2016-01-26 | Cipla Limited | Rifaximin in an amorphous form |
US20080161337A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Chronic Prostatitis |
US20080159987A1 (en) * | 2007-01-03 | 2008-07-03 | Leonard Weinstock | Use of Rifaximin for the Treatment of Restless Legs Syndrome |
ITMI20071241A1 (it) * | 2007-06-20 | 2008-12-21 | Solmag S P A | Processo per la preparazione di rifaximina amorfa e rifaximina amorfa cosi' ottenuta |
AU2008273699A1 (en) | 2007-07-06 | 2009-01-15 | Lupin Limited | Pharmaceutical compositions of rifaximin |
EP2837378A1 (en) | 2007-07-06 | 2015-02-18 | Lupin Limited | Pharmaceutical compositions of rifaximin |
US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
WO2009108730A2 (en) | 2008-02-25 | 2009-09-03 | Salix Pharmaceuticals, Ltd. | Forms of rifaximin and uses thereof |
US8486956B2 (en) | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
EP3563850A1 (en) | 2008-02-26 | 2019-11-06 | Salix Pharmaceuticals, Ltd. | Methods for treating bowel diseases |
US11779571B2 (en) | 2008-02-26 | 2023-10-10 | Salix Pharmaceuticals, Inc. | Methods for treating irritable bowel syndrome (IBS) |
CA2723752A1 (en) | 2008-05-07 | 2009-11-12 | Salix Pharmaceuticals, Ltd. | Methods of treating bowel disease by administering a bowel cleanser and an antibiotic |
EP2324041A4 (en) | 2008-08-13 | 2012-06-13 | Targanta Therapeutics Corp | PHOSPHONIZED RIFAMYCINS AND ITS APPLICATION FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS |
EP2327407B1 (en) | 2008-09-26 | 2014-07-09 | ASKA Pharmaceutical Co., Ltd. | Prophylactic and/or therapeutic agent for functional gastrointestinal disorders |
US12285414B2 (en) | 2008-10-02 | 2025-04-29 | Salix Pharmaceuticals, Inc. | Methods of treating hepatic encephalopathy |
LT3628319T (lt) | 2008-10-02 | 2024-03-25 | Salix Pharmaceuticals, Inc. | Hepatinės encefalopatijos gydymas rifaksiminu |
WO2010067072A1 (en) | 2008-12-10 | 2010-06-17 | Cipla Limited | Rifaximin complexes |
IT1397617B1 (it) * | 2009-04-20 | 2013-01-18 | Alfa Wassermann Spa | Nuovi derivati della rifamicina |
RU2540513C2 (ru) | 2009-06-02 | 2015-02-10 | Саликс Фармасьютикалз, Лтд. | Способы лечения печеночной энцефалопатии |
CN102596250A (zh) | 2009-09-13 | 2012-07-18 | 萨利克斯药品有限公司 | 治疗肠易激综合征(ibs)的方法 |
KR20190000931A (ko) | 2009-10-27 | 2019-01-03 | 루핀 리미티드 | 리팍시민의 고형 분산물 |
NZ600362A (en) | 2009-11-23 | 2014-08-29 | Cipla Ltd | Topical foam composition |
US8952159B2 (en) | 2009-12-28 | 2015-02-10 | Silvio Massimo Lavagna | Method for the production of amorphous rifaximin |
AU2011218129A1 (en) | 2010-02-18 | 2012-08-23 | Board Of Regents Of The University Of Texas System | Methods for treating infection |
IT1398550B1 (it) | 2010-03-05 | 2013-03-01 | Alfa Wassermann Spa | Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo |
JP6092629B2 (ja) | 2010-03-10 | 2017-03-08 | ルピン・リミテッドLupin Limited | リファキシミン使用準備済懸濁液 |
EP3750526A1 (en) | 2010-07-12 | 2020-12-16 | Salix Pharmaceuticals, Inc. | Formulations of rifaximin and uses thereof |
WO2012035544A2 (en) | 2010-09-13 | 2012-03-22 | Sequent Scientific Ltd. | A novel polymorphic form of rifaximin and process for its preparation |
PH12013501643A1 (en) | 2011-02-11 | 2019-10-11 | Salix Pharmaceuticals Ltd | Forms of rifaximin and uses thereof |
EP2705042A1 (en) | 2011-05-02 | 2014-03-12 | Ranbaxy Laboratories Limited | Rifaximin dimethylformamide solvate |
ITMI20110890A1 (it) * | 2011-05-19 | 2012-11-20 | A M S A Anonima Materie Sint & Affini S P A | Polimorfo di rifaximina e processo per la sua preparazione |
ITBO20110461A1 (it) | 2011-07-29 | 2013-01-30 | Alfa Wassermann Spa | Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali. |
RU2496475C2 (ru) | 2011-10-26 | 2013-10-27 | Александр Васильевич Иващенко | Фармацевтическая композиция и набор для лечения бактериальных инфекций |
PL2773205T3 (pl) | 2011-11-02 | 2024-09-02 | Salix Pharmaceuticals, Inc. | Ryfaksymina w leczeniu ustępującej biegunki z przewagą zespołu jelita drażliwego |
JP2015509105A (ja) * | 2012-01-25 | 2015-03-26 | サリックス ファーマスーティカルズ,リミテッド | リファキシミン誘導体及びその使用 |
ITBO20120368A1 (it) | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
US9849090B2 (en) | 2012-12-12 | 2017-12-26 | Sun Pharmaceutical Industries Limited | Pharmaceutical compositions of rifaximin |
JP2016516988A (ja) | 2013-03-15 | 2016-06-09 | アルファ ワッセルマン ソシエタ ペル アチオニAlfa Wassermann S.P.A. | 膣感染症を診断するための方法 |
US20160038468A1 (en) | 2013-03-15 | 2016-02-11 | Alfa Wassermann S.P.A. | Rifaximin for use in the treating of vaginal infections |
PL2983647T3 (pl) | 2013-04-12 | 2021-01-25 | Alfasigma S.P.A. | Podawanie nlpz oraz związane z tym składniki, sposoby i układy |
US9018225B1 (en) | 2013-07-26 | 2015-04-28 | Novel Laboratories | Rifaximin crystalline forms and methods of preparation thereof |
ES2621557T3 (es) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas |
CA2946101A1 (en) * | 2014-04-19 | 2015-10-22 | Granules India Limited | An improved process for the preparation of rifamycin derivatives |
JP6693946B2 (ja) | 2014-05-04 | 2020-05-13 | サリックス ファーマスーティカルズ,インコーポレーテッド | Ibs微生物叢及びその使用 |
KR102362719B1 (ko) | 2014-05-12 | 2022-02-14 | 알파시그마 에스.피.에이. | 리팍시민의 신규한 용매화 결정 형태, 생산물, 조성물 및 이의 용도 |
EP2982764A1 (en) | 2014-08-05 | 2016-02-10 | ALFA WASSERMANN S.p.A. | Identification of vaginal bacteria |
US9988398B2 (en) | 2016-06-07 | 2018-06-05 | Cadila Healthcare Limited | Crystalline form of rifaximin and process for its preparation |
KR20230023043A (ko) | 2016-09-30 | 2023-02-16 | 샐릭스 파마슈티컬스 인코포레이티드 | 리팍시민의 고체 분산물 형태 |
ES2868180T3 (es) | 2017-06-26 | 2021-10-21 | Biofer Spa | Derivados de pirido-imidazo rifamicina como agentes antibacterianos |
IT201700091912A1 (it) * | 2017-08-08 | 2019-02-08 | Biofer Spa | Nuove pirido-imidazo rifamicine |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE273377C (en, 2012) * | ||||
AT273377B (de) * | 1967-03-01 | 1969-08-11 | Lepetit Spa | Verfahren zur Herstellung von neuen Rifamycinen |
AT344898B (de) * | 1975-06-13 | 1978-08-10 | Archifar Ind Chim Trentino | Verfahren zur herstellung neuer rifamycin-verbindungen |
DK345977A (da) * | 1976-09-30 | 1978-03-31 | Archifar Ind Chim Trentino | G rifamycinforbindelser og fremgangsmaade til deres fremstillin |
CH629212A5 (it) * | 1976-10-18 | 1982-04-15 | Erba Farmitalia | Procedimento per la preparazione di composti di rifamicina. |
CH633014A5 (en) * | 1978-06-09 | 1982-11-15 | Erba Farmitalia | Rifamycin compounds |
-
1980
- 1980-05-22 IT IT03429/80A patent/IT1154655B/it active Protection Beyond IP Right Term
-
1981
- 1981-05-11 NL NLAANVRAGE8102290,A patent/NL187022C/xx not_active IP Right Cessation
- 1981-05-11 US US06/262,123 patent/US4341785A/en not_active Expired - Lifetime
- 1981-05-18 AU AU70655/81A patent/AU537093B2/en not_active Expired
- 1981-05-19 AT AT0222781A patent/AT373599B/de not_active IP Right Cessation
- 1981-05-20 EG EG280/81A patent/EG14891A/xx active
- 1981-05-20 FR FR8110058A patent/FR2482967A1/fr active Granted
- 1981-05-20 PH PH25656A patent/PH17207A/en unknown
- 1981-05-20 GR GR65010A patent/GR75640B/el unknown
- 1981-05-20 LU LU83376A patent/LU83376A1/fr unknown
- 1981-05-20 PT PT73064A patent/PT73064B/pt unknown
- 1981-05-21 CA CA000378015A patent/CA1142518A/en not_active Expired
- 1981-05-21 DK DK224781A patent/DK157876C/da active
- 1981-05-21 IE IE1139/81A patent/IE51204B1/en not_active IP Right Cessation
- 1981-05-21 ZA ZA00813430A patent/ZA813430B/xx unknown
- 1981-05-21 NO NO811731A patent/NO155622C/no unknown
- 1981-05-21 SE SE8103216A patent/SE453089B/sv not_active IP Right Cessation
- 1981-05-21 FI FI811565A patent/FI69467C/fi not_active IP Right Cessation
- 1981-05-21 ES ES502906A patent/ES502906A0/es active Granted
- 1981-05-21 BE BE2/59169A patent/BE888895A/fr not_active IP Right Cessation
- 1981-05-22 DE DE19813120460 patent/DE3120460A1/de active Granted
- 1981-05-22 CH CH3381/81A patent/CH648037A5/de not_active IP Right Cessation
- 1981-05-22 GB GB8115790A patent/GB2079270B/en not_active Expired
- 1981-05-22 JP JP7787781A patent/JPS5711987A/ja active Granted
- 1981-05-22 AR AR285424A patent/AR226212A1/es active
-
1982
- 1982-02-09 PH PH26842A patent/PH18704A/en unknown
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A85 | Still pending on 85-01-01 | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
V4 | Discontinued because of reaching the maximum lifetime of a patent |
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