NL1008021C2 - Nieuwe formulering voor inhalatie. - Google Patents

Nieuwe formulering voor inhalatie. Download PDF

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Publication number
NL1008021C2
NL1008021C2 NL1008021A NL1008021A NL1008021C2 NL 1008021 C2 NL1008021 C2 NL 1008021C2 NL 1008021 A NL1008021 A NL 1008021A NL 1008021 A NL1008021 A NL 1008021A NL 1008021 C2 NL1008021 C2 NL 1008021C2
Authority
NL
Netherlands
Prior art keywords
composition according
active substance
bulk density
substance
formulation
Prior art date
Application number
NL1008021A
Other languages
English (en)
Dutch (nl)
Other versions
NL1008021A1 (nl
Inventor
Jan Trofast
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20405453&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL1008021(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Publication of NL1008021A1 publication Critical patent/NL1008021A1/xx
Application granted granted Critical
Publication of NL1008021C2 publication Critical patent/NL1008021C2/nl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NL1008021A 1997-01-20 1998-01-13 Nieuwe formulering voor inhalatie. NL1008021C2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9700134 1997-01-20
SE9700134A SE9700134D0 (sv) 1997-01-20 1997-01-20 New formulation

Publications (2)

Publication Number Publication Date
NL1008021A1 NL1008021A1 (nl) 1998-07-22
NL1008021C2 true NL1008021C2 (nl) 1998-10-07

Family

ID=20405453

Family Applications (1)

Application Number Title Priority Date Filing Date
NL1008021A NL1008021C2 (nl) 1997-01-20 1998-01-13 Nieuwe formulering voor inhalatie.

Country Status (32)

Country Link
EP (1) EP1009394B1 (zh)
JP (2) JP4512203B2 (zh)
KR (1) KR100528417B1 (zh)
CN (1) CN1213741C (zh)
AT (1) ATE257699T1 (zh)
AU (1) AU728835B2 (zh)
BE (1) BE1011401A3 (zh)
BR (1) BR9806895A (zh)
CA (1) CA2277890C (zh)
CZ (1) CZ295682B6 (zh)
DE (1) DE69821119T2 (zh)
DK (1) DK1009394T3 (zh)
EE (1) EE04038B1 (zh)
ES (2) ES2212262T3 (zh)
FR (1) FR2759907B1 (zh)
GR (1) GR980100022A (zh)
HU (1) HU228682B1 (zh)
ID (1) ID21917A (zh)
IE (1) IE980025A1 (zh)
IL (1) IL130837A0 (zh)
IS (1) IS2243B (zh)
NL (1) NL1008021C2 (zh)
NO (1) NO327457B1 (zh)
NZ (1) NZ336593A (zh)
PL (1) PL189552B1 (zh)
PT (1) PT1009394E (zh)
RU (1) RU2180220C2 (zh)
SE (1) SE9700134D0 (zh)
SK (1) SK283949B6 (zh)
TR (1) TR199901692T2 (zh)
UA (1) UA57763C2 (zh)
WO (1) WO1998031351A1 (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9703407D0 (sv) 1997-09-19 1997-09-19 Astra Ab New use
SE9802073D0 (sv) 1998-06-11 1998-06-11 Astra Ab New use
ITMI991582A1 (it) 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
GB9928311D0 (en) * 1999-11-30 2000-01-26 Novartis Ag Organic compounds
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0012261D0 (en) * 2000-05-19 2000-07-12 Astrazeneca Ab Novel process
GB0012260D0 (en) 2000-05-19 2000-07-12 Astrazeneca Ab Novel composition
ITMI20010428A1 (it) * 2001-03-02 2002-09-02 Chemo Breath S A Composizioni ad uso inalatorio a base di formoterolo
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
SE0200657D0 (sv) * 2002-03-04 2002-03-04 Astrazeneca Ab Novel Formulation
GB0312148D0 (en) 2003-05-28 2003-07-02 Aventis Pharma Ltd Stabilized pharmaceutical products
GB0315889D0 (en) 2003-07-08 2003-08-13 Aventis Pharma Ltd Stable pharmaceutical products
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
DE102007049931A1 (de) 2007-10-18 2009-04-23 Pharmatech Gmbh Vorrichtung und Verfahren zur kontinuierlichen Herstellung von sphärischen Pulveragglomeraten
US20110224229A1 (en) 2010-03-10 2011-09-15 Astrazeneca Ab Novel Crystalline Form
TR201802969T4 (tr) 2013-07-01 2018-03-21 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Yeni inhalasyon formülasyonları.
WO2015060743A1 (ru) * 2013-10-21 2015-04-30 Шолекс Девелопмент Гмбх Ингаляционный препарат для лечения болезней органов дыхания, содержащий в качестве активных веществ микронизированный салметерол ксинофоат и микронизированный флутиказона пропионат и способ его получения
KR20220066906A (ko) 2019-09-24 2022-05-24 키에시 파르마슈티시 엣스. 피. 에이. 흡입용 건조 분말 제제를 위한 신규 담체 입자

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005805A1 (en) * 1993-08-27 1995-03-02 Astra Aktiebolag Process for conditioning substances
WO1995009616A1 (en) * 1993-10-01 1995-04-13 Astra Aktiebolag Process ii
WO1998015280A1 (en) * 1996-10-08 1998-04-16 Astra Aktiebolag New combination

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE17441T1 (de) * 1981-07-24 1986-02-15 Fisons Plc Inhalierbare arzneimittel, verfahren zu deren herstellung und pharmazeutische formulierungen diese enthaltend.
EP0072046B1 (en) * 1981-07-24 1986-01-15 FISONS plc Inhalation drugs, methods for their production and pharmaceutical formulations containing them
WO1993011773A1 (en) * 1991-12-18 1993-06-24 Aktiebolaget Astra New combination of formoterol and budesonide
DK0721331T3 (da) * 1993-10-01 2002-02-11 Astrazeneca Ab Fremgangsmåde

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005805A1 (en) * 1993-08-27 1995-03-02 Astra Aktiebolag Process for conditioning substances
WO1995009616A1 (en) * 1993-10-01 1995-04-13 Astra Aktiebolag Process ii
WO1998015280A1 (en) * 1996-10-08 1998-04-16 Astra Aktiebolag New combination

Also Published As

Publication number Publication date
UA57763C2 (uk) 2003-07-15
NZ336593A (en) 2001-01-26
IE980025A1 (en) 1998-10-07
ATE257699T1 (de) 2004-01-15
JP4512203B2 (ja) 2010-07-28
AU728835B2 (en) 2001-01-18
IS2243B (is) 2007-05-15
NO327457B1 (no) 2009-07-06
FR2759907A1 (fr) 1998-08-28
ES2149082B1 (es) 2001-05-16
EP1009394A1 (en) 2000-06-21
ES2212262T3 (es) 2004-07-16
ID21917A (id) 1999-08-12
WO1998031351A1 (en) 1998-07-23
EE04038B1 (et) 2003-06-16
CA2277890C (en) 2006-08-29
PL334528A1 (en) 2000-02-28
NO993538L (no) 1999-09-17
CN1213741C (zh) 2005-08-10
CZ295682B6 (cs) 2005-09-14
EP1009394B1 (en) 2004-01-14
PL189552B1 (pl) 2005-08-31
CZ255699A3 (cs) 1999-10-13
DK1009394T3 (da) 2004-04-05
BR9806895A (pt) 2000-05-16
CN1243435A (zh) 2000-02-02
NL1008021A1 (nl) 1998-07-22
JP2001508792A (ja) 2001-07-03
BE1011401A3 (fr) 1999-08-03
ES2149082A1 (es) 2000-10-16
RU2180220C2 (ru) 2002-03-10
PT1009394E (pt) 2004-05-31
SE9700134D0 (sv) 1997-01-20
EE9900294A (et) 2000-02-15
KR100528417B1 (ko) 2005-11-16
CA2277890A1 (en) 1998-07-23
HUP0000843A3 (en) 2000-10-30
TR199901692T2 (xx) 1999-09-21
DE69821119T2 (de) 2004-08-19
NO993538D0 (no) 1999-07-19
SK283949B6 (sk) 2004-05-04
FR2759907B1 (fr) 2001-03-09
HUP0000843A2 (hu) 2000-09-28
DE69821119D1 (de) 2004-02-19
IL130837A0 (en) 2001-01-28
SK95899A3 (en) 2000-01-18
HU228682B1 (en) 2013-05-28
GR980100022A (el) 1998-09-30
KR20000070187A (ko) 2000-11-25
JP2010059180A (ja) 2010-03-18
IS5109A (is) 1999-07-06
AU5785898A (en) 1998-08-07

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Legal Events

Date Code Title Description
AD1A A request for search or an international type search has been filed
RD2N Patents in respect of which a decision has been taken or a report has been made (novelty report)

Effective date: 19980805

PD2B A search report has been drawn up
MK Patent expired because of reaching the maximum lifetime of a patent

Effective date: 20180112