MY173378A - Efficient lipid delivery to human tear film using a salt-sensitive emulsion system - Google Patents
Efficient lipid delivery to human tear film using a salt-sensitive emulsion systemInfo
- Publication number
- MY173378A MY173378A MYPI2014001672A MYPI2014001672A MY173378A MY 173378 A MY173378 A MY 173378A MY PI2014001672 A MYPI2014001672 A MY PI2014001672A MY PI2014001672 A MYPI2014001672 A MY PI2014001672A MY 173378 A MY173378 A MY 173378A
- Authority
- MY
- Malaysia
- Prior art keywords
- salt
- tear film
- sensitive emulsion
- emulsion system
- human tear
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title abstract 2
- 150000002632 lipids Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 208000003556 Dry Eye Syndromes Diseases 0.000 abstract 1
- 206010013774 Dry eye Diseases 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
- 239000004006 olive oil Substances 0.000 abstract 1
- 235000008390 olive oil Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161568089P | 2011-12-07 | 2011-12-07 | |
| US201261625401P | 2012-04-17 | 2012-04-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY173378A true MY173378A (en) | 2020-01-21 |
Family
ID=47459152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2014001672A MY173378A (en) | 2011-12-07 | 2012-12-07 | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
Country Status (27)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8957048B2 (en) * | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| SI3266446T1 (sl) | 2016-07-07 | 2019-02-28 | Laboratorios Salvat, S.A. | Oftalmična sestava, obsegajoča ricinusovo olje in triglicerid s srednjo verigo |
| JP2019524892A (ja) | 2016-08-19 | 2019-09-05 | アクリビスタ エルエルシーＡｋｒｉｖｉｓｔａ，Ｌｌｃ | ドライアイ症候群を診断及び治療する方法ならびにヒト眼を治療するための組成物 |
| CN114376961A (zh) | 2017-08-18 | 2022-04-22 | 阿克里维斯塔有限责任公司 | 诊断和治疗干眼综合症的方法和用于治疗人类眼睛的组合物 |
| EP3784354A1 (en) | 2018-04-27 | 2021-03-03 | Allergan, Inc. | Sodium chlorite compositions with enhanced anti-microbial efficacy and reduced toxicity |
| WO2025175150A1 (en) * | 2024-02-16 | 2025-08-21 | Allergan, Inc. | Enhanced artificial tear formulations |
Family Cites Families (40)
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| US4201706A (en) | 1978-09-22 | 1980-05-06 | Burton, Parsons & Company, Inc. | Treatment of corneal edema |
| ATE6466T1 (de) * | 1979-10-26 | 1984-03-15 | Smith And Nephew Associated Companies P.L.C. | Autoklavierbare emulsionen. |
| US5192535A (en) | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| IT1224795B (it) | 1988-12-01 | 1990-10-24 | Sigma Tau Ind Farmaceuti | Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento |
| DE69004066T2 (de) | 1989-08-03 | 1994-02-17 | Eisai Co Ltd | Verfahren zur photostabilisierung von augenspüllösungen. |
| US5681555A (en) | 1991-04-22 | 1997-10-28 | Gleich; Gerald J. | Method for the treatment of bronchial asthma by parenteral administration of anionic polymers |
| DE4229494A1 (de) | 1992-09-04 | 1994-03-10 | Basotherm Gmbh | Arzneimittel zur topischen Anwendung am Auge zur Behandlung des erhöhten intraokularen Drucks |
| CA2199610A1 (en) | 1994-09-14 | 1996-03-21 | Taisho Pharmaceutical Co., Ltd. | Eye drops for repairing repairing corneal damage |
| US5980865A (en) | 1995-08-18 | 1999-11-09 | Baker Norton Pharmaceuticals, Inc. | Method for treating late phase allergic reactions and inflammatory diseases |
| FI106923B (fi) | 1997-01-03 | 2001-05-15 | Cultor Ltd Finnsugar Bioproduc | Trimetyyliglysiinin käyttö kehon limakalvojen hygieniaan ja hoitoon tarkoitetuissa valmisteissa |
| AR002194A1 (es) | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
| IT1302307B1 (it) | 1998-09-01 | 2000-09-05 | Sigma Tau Healthscience Spa | Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil |
| WO2000029030A1 (en) | 1998-11-13 | 2000-05-25 | Continental Projects Limited | Complexes of hyaluronic acid/carnitines and pharmaceutical and cosmetic compositions |
| JP2000159659A (ja) * | 1998-11-30 | 2000-06-13 | Kazuo Tsubota | 眼科用人工涙液 |
| US6228392B1 (en) | 1999-04-29 | 2001-05-08 | Gene Tools, Llc | Osmotic delivery composition, solution, and method |
| RU2291685C2 (ru) | 2000-07-14 | 2007-01-20 | Аллерган Инк. | Композиции, содержащие терапевтически активные компоненты, обладающие повышенной растворимостью |
| AU781975B2 (en) | 2000-09-14 | 2005-06-23 | Hayashibara Co., Ltd | Pharmaceutical composition for ophthalmic use |
| AU2002227206B2 (en) | 2000-11-08 | 2006-09-21 | Fxs Ventures, Llc | Improved ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers |
| US7045121B2 (en) | 2001-12-14 | 2006-05-16 | Allergan, Inc. | Ophthalmic compositions for lubricating eyes and methods for making and using same |
| US7795203B2 (en) | 2002-09-30 | 2010-09-14 | Babizhayev Mark A | Method for topical treatment of eye disease and composition and device for said treatment |
| BR0306662A (pt) * | 2002-10-18 | 2005-02-22 | Joel S Echols | Formulação lacrimal de três camadas |
| US20040137079A1 (en) | 2003-01-08 | 2004-07-15 | Cook James N. | Contact lens and eye drop rewetter compositions and methods |
| US6635654B1 (en) * | 2003-01-09 | 2003-10-21 | Allergan, Inc. | Ophthalmic compositions containing loratadine |
| US20040185068A1 (en) * | 2003-03-18 | 2004-09-23 | Zhi-Jian Yu | Self-emulsifying compositions, methods of use and preparation |
| EP1611883A1 (en) | 2003-03-26 | 2006-01-04 | Menicon Co., Ltd. | Composition for ophthalmic use |
| CN100475192C (zh) * | 2003-06-13 | 2009-04-08 | 爱尔康公司 | 包含两种聚合物的协同组合的眼用组合物 |
| TWI336257B (en) * | 2003-06-13 | 2011-01-21 | Alcon Inc | Ophthalmic compositions containing a synergistic combination of three polymers |
| US20050009836A1 (en) | 2003-06-26 | 2005-01-13 | Laskar Paul A. | Ophthalmic composition containing quinolones and method of use |
| WO2005046728A1 (ja) * | 2003-11-10 | 2005-05-26 | Toray Industries, Inc. | 多糖類含有組成物および涙液層安定化点眼剤 |
| US8569367B2 (en) * | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| US7288520B2 (en) * | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
| US7501393B2 (en) * | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
| US9561178B2 (en) * | 2006-07-25 | 2017-02-07 | Allergan, Inc. | Cyclosporin compositions |
| WO2008035246A2 (en) * | 2006-07-28 | 2008-03-27 | Novagali Pharma Sa | Compositions containing quaternary ammonium compounds |
| CN101896160A (zh) * | 2006-10-17 | 2010-11-24 | 阿勒根公司 | 环胞菌素组合物 |
| EP2131809A2 (en) * | 2007-02-28 | 2009-12-16 | Aciex Therapeutics, Inc. | Methods and compositions for normalizing meibomian gland secretions |
| JP4929245B2 (ja) | 2008-07-31 | 2012-05-09 | 株式会社ベッセル工業 | 工具類のグリップ |
| PL2437762T3 (pl) * | 2009-06-05 | 2018-01-31 | Allergan Inc | Sztuczne łzy i ich zastosowania terapeutyczne |
| WO2013049621A1 (en) * | 2011-09-29 | 2013-04-04 | The Board Of Regents Of The University Of Oklahoma | Ophthalmic compositions comprising ppar-alpha agonists and methods of production and use thereof |
| US8957048B2 (en) * | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
-
2012
- 2012-12-07 PT PT128086063T patent/PT2787968T/pt unknown
- 2012-12-07 PL PL12808607T patent/PL2787969T3/pl unknown
- 2012-12-07 TW TW101146304A patent/TWI652072B/zh active
- 2012-12-07 CN CN201280067685.0A patent/CN104114152A/zh active Pending
- 2012-12-07 US US13/708,771 patent/US9314528B2/en active Active
- 2012-12-07 EP EP12808607.1A patent/EP2787969B1/en active Active
- 2012-12-07 IN IN4809CHN2014 patent/IN2014CN04809A/en unknown
- 2012-12-07 US US13/708,783 patent/US20130150324A1/en not_active Abandoned
- 2012-12-07 PL PL12808606T patent/PL2787968T3/pl unknown
- 2012-12-07 WO PCT/US2012/068603 patent/WO2013086438A1/en not_active Ceased
- 2012-12-07 HU HUE12808606A patent/HUE049489T2/hu unknown
- 2012-12-07 EP EP12808606.3A patent/EP2787968B1/en active Active
- 2012-12-07 ES ES12808607T patent/ES2896336T3/es active Active
- 2012-12-07 SG SG11201403013VA patent/SG11201403013VA/en unknown
- 2012-12-07 MY MYPI2014001672A patent/MY173378A/en unknown
- 2012-12-07 AU AU2012347459A patent/AU2012347459A1/en not_active Abandoned
- 2012-12-07 PH PH1/2021/553172A patent/PH12021553172A1/en unknown
- 2012-12-07 CA CA2858574A patent/CA2858574C/en active Active
- 2012-12-07 AR ARP120104614A patent/AR089123A1/es not_active Application Discontinuation
- 2012-12-07 EP EP21198843.1A patent/EP3981387A1/en active Pending
- 2012-12-07 RU RU2014127074A patent/RU2014127074A/ru unknown
- 2012-12-07 EP EP20153344.5A patent/EP3666257A1/en not_active Withdrawn
- 2012-12-07 DK DK12808606.3T patent/DK2787968T3/da active
- 2012-12-07 JP JP2014546154A patent/JP6142419B2/ja active Active
- 2012-12-07 SI SI201231783T patent/SI2787968T1/sl unknown
- 2012-12-07 EP EP24167560.2A patent/EP4403220A3/en active Pending
- 2012-12-07 HU HUE12808607A patent/HUE057140T2/hu unknown
- 2012-12-07 PH PH1/2014/501296A patent/PH12014501296B1/en unknown
- 2012-12-07 DK DK12808607.1T patent/DK2787969T3/da active
- 2012-12-07 WO PCT/US2012/068615 patent/WO2013086449A1/en not_active Ceased
- 2012-12-07 ES ES12808606T patent/ES2797650T3/es active Active
- 2012-12-07 BR BR112014013820A patent/BR112014013820A2/pt not_active Application Discontinuation
- 2012-12-07 SI SI201231957T patent/SI2787969T1/sl unknown
- 2012-12-07 MX MX2014006804A patent/MX355216B/es active IP Right Grant
- 2012-12-07 CN CN201810890387.0A patent/CN108969482A/zh active Pending
- 2012-12-07 KR KR1020147018598A patent/KR102017922B1/ko not_active Expired - Fee Related
- 2012-12-07 PT PT128086071T patent/PT2787969T/pt unknown
-
2014
- 2014-06-08 IL IL233008A patent/IL233008A/en active IP Right Grant
- 2014-06-09 ZA ZA2014/04228A patent/ZA201404228B/en unknown
- 2014-06-09 CL CL2014001518A patent/CL2014001518A1/es unknown
- 2014-06-26 CO CO14138315A patent/CO6990739A2/es unknown
-
2017
- 2017-11-27 AU AU2017265181A patent/AU2017265181B2/en active Active
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