MX2015001804A - Metodos y composiciones para el tratamiento de condiciones relacionadas con la falta del suministro de sangre, choque y lesiones neuronales. - Google Patents

Metodos y composiciones para el tratamiento de condiciones relacionadas con la falta del suministro de sangre, choque y lesiones neuronales.

Info

Publication number
MX2015001804A
MX2015001804A MX2015001804A MX2015001804A MX2015001804A MX 2015001804 A MX2015001804 A MX 2015001804A MX 2015001804 A MX2015001804 A MX 2015001804A MX 2015001804 A MX2015001804 A MX 2015001804A MX 2015001804 A MX2015001804 A MX 2015001804A
Authority
MX
Mexico
Prior art keywords
lack
conditions related
blood supply
treating conditions
shock
Prior art date
Application number
MX2015001804A
Other languages
English (en)
Inventor
Cuthbert O Simpkins
Original Assignee
Cuthbert O Simpkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cuthbert O Simpkins filed Critical Cuthbert O Simpkins
Publication of MX2015001804A publication Critical patent/MX2015001804A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Se describe una composición farmacéutica que comprende un emulsionante anfifílico, un portador líquido polar y, opcionalmente, un componente lípídico. El emulsionante anfifílico forma micelas, que portan opcionalmente lipídos (LMs) de movimiento libre en el portador líquido polar. La composición farmacéutica está libre de la hemoglobina y fluorocarbono y se puede utilizar para el tratamiento de condiciones relacionadas con la falta de suministro de sangre y para elevar la presión sanguínea y corregir la hipovolemia.
MX2015001804A 2012-08-10 2013-08-09 Metodos y composiciones para el tratamiento de condiciones relacionadas con la falta del suministro de sangre, choque y lesiones neuronales. MX2015001804A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261681930P 2012-08-10 2012-08-10
PCT/US2013/054356 WO2014026121A1 (en) 2012-08-10 2013-08-09 Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries

Publications (1)

Publication Number Publication Date
MX2015001804A true MX2015001804A (es) 2015-09-23

Family

ID=50068606

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015001804A MX2015001804A (es) 2012-08-10 2013-08-09 Metodos y composiciones para el tratamiento de condiciones relacionadas con la falta del suministro de sangre, choque y lesiones neuronales.

Country Status (4)

Country Link
EP (1) EP2882451B1 (es)
BR (1) BR112015002807A2 (es)
MX (1) MX2015001804A (es)
WO (1) WO2014026121A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201512728D0 (en) 2015-07-20 2015-08-26 Isis Innovation Nanoencapsulated oxygen
US20180368393A1 (en) * 2017-06-26 2018-12-27 Cpsi Holdings Llc Pre- and post-storage stress response conditioning

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284645A (en) * 1987-08-05 1994-02-08 Alliance Pharmaceutical Corp. Fluorocarbon emulsions containing amino acid based anti-inflamatory agents and buffer systems
US6281175B1 (en) * 1997-09-23 2001-08-28 Scimed Life Systems, Inc. Medical emulsion for lubrication and delivery of drugs
US7261903B1 (en) * 1999-02-22 2007-08-28 Guy Weinberg Lipid emulsions in the treatment of systemic poisoning
US7357937B2 (en) * 2002-09-24 2008-04-15 Therox, Inc. Perfluorocarbon emulsions with non-fluorinated surfactants
US7754247B2 (en) * 2007-05-29 2010-07-13 University Of South Carolina Resuscitation fluid
US8063020B2 (en) * 2007-12-22 2011-11-22 Simpkins Cuthbert O Resuscitation fluid
CA2749698C (en) * 2009-01-30 2017-08-01 Cuthbert O. Simpkins Resuscitation fluid
CN103491976B (zh) * 2011-01-14 2015-04-01 卡思伯特·O·辛普金斯 用于处理与缺乏血液供给、休克和神经损伤相关的疾病的方法和组合物

Also Published As

Publication number Publication date
BR112015002807A2 (pt) 2018-03-20
EP2882451B1 (en) 2020-09-23
EP2882451A1 (en) 2015-06-17
WO2014026121A1 (en) 2014-02-13
EP2882451A4 (en) 2015-12-09

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