BR112014001118A2 - combinação tópica para aplicação oftálmica e uso de bimatoprost e brimonidina - Google Patents

combinação tópica para aplicação oftálmica e uso de bimatoprost e brimonidina

Info

Publication number
BR112014001118A2
BR112014001118A2 BR112014001118A BR112014001118A BR112014001118A2 BR 112014001118 A2 BR112014001118 A2 BR 112014001118A2 BR 112014001118 A BR112014001118 A BR 112014001118A BR 112014001118 A BR112014001118 A BR 112014001118A BR 112014001118 A2 BR112014001118 A2 BR 112014001118A2
Authority
BR
Brazil
Prior art keywords
bimatoprost
brimonidine
ophthalmic application
topical combination
combination
Prior art date
Application number
BR112014001118A
Other languages
English (en)
Inventor
V Gore Anuradha
P Pujara Chetan
S Warner Kevin
s graham Richard
Neervannan Sesha
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of BR112014001118A2 publication Critical patent/BR112014001118A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

resumo patente de invenção: "combinação de dose fixa de bimatoprost e brimonidina". a presente invenção é direcionada para composições que compreendem combinações de brimonidina e bimatoprost úteis para diminuir a pressão intraocular em um paciente e para o tratamento do glaucoma.
BR112014001118A 2011-07-20 2012-07-20 combinação tópica para aplicação oftálmica e uso de bimatoprost e brimonidina BR112014001118A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161509666P 2011-07-20 2011-07-20
PCT/US2012/047586 WO2013013143A1 (en) 2011-07-20 2012-07-20 Fixed dose combination of bimatoprost and brimonidine

Publications (1)

Publication Number Publication Date
BR112014001118A2 true BR112014001118A2 (pt) 2017-02-14

Family

ID=46599013

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014001118A BR112014001118A2 (pt) 2011-07-20 2012-07-20 combinação tópica para aplicação oftálmica e uso de bimatoprost e brimonidina

Country Status (13)

Country Link
US (2) US20130023536A1 (pt)
EP (1) EP2734206A1 (pt)
JP (2) JP2014520895A (pt)
KR (1) KR20140056280A (pt)
CN (1) CN103747786A (pt)
AU (1) AU2012283895A1 (pt)
BR (1) BR112014001118A2 (pt)
CA (1) CA2841969A1 (pt)
CO (1) CO6880070A2 (pt)
IL (1) IL230450A0 (pt)
MX (1) MX2014000781A (pt)
RU (1) RU2014103544A (pt)
WO (1) WO2013013143A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2014129268A (ru) * 2011-12-16 2016-02-10 Аллерган, Инк. Офтальмологические составы, которые содержат привитые сополимеры поливинилкапролактам-поливинилацетат-полиэтиленгликоля
US9248135B2 (en) 2012-04-24 2016-02-02 Allergan, Inc. Prostaglandin and vasoconstrictor pharmaceutical compositions and methods of use
NO2753788T3 (pt) * 2013-05-10 2018-06-16
US9820993B2 (en) 2013-05-15 2017-11-21 Topokine Therapeutics, Inc. Methods and compositions for topical delivery of prostaglandins to subcutaneous fat
UA118576C2 (uk) * 2014-01-24 2019-02-11 Сентис Фарма Прайвет Лімітед Фармацевтична композиція, яка містить бринзоламід
WO2016063184A1 (en) * 2014-10-20 2016-04-28 Sentiss Pharma Private Limited Ophthalmic solution
TWI699205B (zh) * 2014-12-12 2020-07-21 日商興和股份有限公司 用於預防或治療青光眼之藥物療法
CN107405303A (zh) * 2015-03-24 2017-11-28 陶氏环球技术有限责任公司 聚合物的水溶液
PL3103439T3 (pl) * 2015-06-09 2019-12-31 Medproject Pharma-Entwicklungs- Und Vertriebsgesellschaft Mbh Zdolny do tworzenia kropli oftalmiczny żel bimatoprostu
US20180353504A1 (en) * 2017-06-08 2018-12-13 Eye Therapies, Llc Low-dose brimonidine combinations and uses thereof
KR102115285B1 (ko) 2017-06-22 2020-05-26 연성정밀화학(주) 녹내장 치료용 점안 조성물
JP7170436B2 (ja) * 2017-06-28 2022-11-14 千寿製薬株式会社 水溶性高分子を含む点眼剤
WO2020219707A1 (en) * 2019-04-24 2020-10-29 Allergan, Inc. Compositions and methods for treatment of ocular conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2001A (en) * 1841-03-12 Sawmill
WO1996013267A2 (en) * 1994-10-27 1996-05-09 Allergan Combinations of prostaglandins and brimonidine or derivatives thereof for the treatment of glaucoma

Also Published As

Publication number Publication date
JP2015110672A (ja) 2015-06-18
JP2014520895A (ja) 2014-08-25
CO6880070A2 (es) 2014-02-28
IL230450A0 (en) 2014-03-31
KR20140056280A (ko) 2014-05-09
EP2734206A1 (en) 2014-05-28
AU2012283895A1 (en) 2014-02-06
CN103747786A (zh) 2014-04-23
MX2014000781A (es) 2014-04-30
RU2014103544A (ru) 2015-08-27
US20140249153A1 (en) 2014-09-04
CA2841969A1 (en) 2013-01-24
US20130023536A1 (en) 2013-01-24
WO2013013143A1 (en) 2013-01-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]