BR0306662A - Formulação lacrimal de três camadas - Google Patents

Formulação lacrimal de três camadas

Info

Publication number
BR0306662A
BR0306662A BR0306662-2A BR0306662A BR0306662A BR 0306662 A BR0306662 A BR 0306662A BR 0306662 A BR0306662 A BR 0306662A BR 0306662 A BR0306662 A BR 0306662A
Authority
BR
Brazil
Prior art keywords
layer
over
phospholipid
layer tear
tear film
Prior art date
Application number
BR0306662-2A
Other languages
English (en)
Inventor
Joel S Echols
Frank J Holly
Wolfgang Widera
Original Assignee
Joel S Echols
Frank J Holly
Wolfgang Widera
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Joel S Echols, Frank J Holly, Wolfgang Widera filed Critical Joel S Echols
Publication of BR0306662A publication Critical patent/BR0306662A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Abstract

"FORMULAçãO LACRIMAL DE TRêS CAMADAS".Refere-se o presente invento a um filme lacrimal artificial sobre a superfície de um olho tendo uma primeira camada em contato direto com a superfície ocular, uma camada aquosa sobre a primeira camada, e uma camada de um fosfolipídeo sobre a camada aquosa. A primeira camada tem poli(álcool vinílico), poli(acetato de vinilo), e poli(vinil pirrolidona). O fosfolipídeo é derivado de Amisol<32> Clear. O filme lacrimal artificial é efetivo no prolongamento significativo do tempo de ruptura da lágrima em pacientes com a síndrome do olho seco.
BR0306662-2A 2002-10-18 2003-10-17 Formulação lacrimal de três camadas BR0306662A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41942802P 2002-10-18 2002-10-18
PCT/US2003/033078 WO2004035005A2 (en) 2002-10-18 2003-10-17 Three layer tear formulation

Publications (1)

Publication Number Publication Date
BR0306662A true BR0306662A (pt) 2005-02-22

Family

ID=32108079

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0306662-2A BR0306662A (pt) 2002-10-18 2003-10-17 Formulação lacrimal de três camadas

Country Status (11)

Country Link
US (1) US7758883B2 (pt)
EP (1) EP1551417B1 (pt)
JP (1) JP2006507275A (pt)
KR (1) KR20050059175A (pt)
AT (1) ATE407662T1 (pt)
AU (1) AU2003301263A1 (pt)
BR (1) BR0306662A (pt)
DE (1) DE60323520D1 (pt)
ES (1) ES2314284T3 (pt)
PT (1) PT1551417E (pt)
WO (1) WO2004035005A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2498717A1 (en) * 2002-09-13 2004-03-25 Ocular Sciences, Inc. Devices and methods for improving vision
CN1870906A (zh) * 2004-07-22 2006-11-29 德国阿奎诺瓦增溶技术有限公司 醚油和其他物质的溶解物
WO2007076274A2 (en) * 2005-12-22 2007-07-05 Bausch & Lomb Incorporated Artificial tear solution containing poly (ethylene glycol) peg lipids
US7883520B2 (en) 2006-04-10 2011-02-08 Forsight Labs, Llc Corneal epithelial pocket formation systems, components and methods
WO2008036258A2 (en) * 2006-09-18 2008-03-27 Aqueous Pharma Limited Collyrium for dry eye
US20100087550A1 (en) * 2008-10-06 2010-04-08 Zora Marlowe Formulations with a Tertiary Amine Oxide
ES2896336T3 (es) * 2011-12-07 2022-02-24 Allergan Inc Suministro eficiente de lípidos a película lagrimal humana usando un sistema de emulsión sensible a sales
WO2013102907A1 (en) * 2012-01-08 2013-07-11 Medicure Technologies Ltd. Ophthalmic composition
WO2019231853A1 (en) * 2018-06-01 2019-12-05 Aurora Tears Technology, Inc. Systems and methods for generating and applying biomimicry tear films
US11253395B2 (en) * 2018-06-01 2022-02-22 Aurora Tears Technology, Inc. Systems and methods for generating and applying biomimicry tear films
US11918603B2 (en) * 2018-08-30 2024-03-05 Harrow Ip, Llc Ocular lubricant formulations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2897120A (en) * 1954-05-04 1959-07-28 Upjohn Co Low viscosity cmc pharmaceutical vehicle
EP0083370A1 (en) 1981-07-08 1983-07-13 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
US4421748A (en) 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
US4744980A (en) * 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4818537A (en) * 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US4923699A (en) 1988-06-03 1990-05-08 Kaufman Herbert E Eye treatment suspension
US5221696A (en) 1989-03-29 1993-06-22 Alcon Laboratories, Inc. Use of monoacyl phosphoglycerides to enhance the corneal penetration of ophthalmic drugs
ZA927277B (en) * 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
US5290572A (en) 1992-08-06 1994-03-01 Deo Corporation Opthalmic composition for treating dry eye
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
ZA966579B (en) * 1995-08-04 1998-02-02 Wakamoto Pharma Co Ltd O/W emulsion composition for eye drops.
US5800807A (en) 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
EP1020194A4 (en) 1997-10-01 2003-05-21 Wakamoto Pharma Co Ltd OIL / WATER EMULSION COMPILATIONS
DK1228028T3 (da) 1999-11-09 2005-11-14 Alcon Inc Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser
US6565861B1 (en) 2000-02-11 2003-05-20 Isis Innovation Limited Artificial tear formulation

Also Published As

Publication number Publication date
JP2006507275A (ja) 2006-03-02
KR20050059175A (ko) 2005-06-17
PT1551417E (pt) 2008-10-31
EP1551417A2 (en) 2005-07-13
EP1551417B1 (en) 2008-09-10
ES2314284T3 (es) 2009-03-16
EP1551417A4 (en) 2006-03-01
WO2004035005A3 (en) 2004-09-16
AU2003301263A8 (en) 2004-05-04
DE60323520D1 (de) 2008-10-23
ATE407662T1 (de) 2008-09-15
US7758883B2 (en) 2010-07-20
US20040142038A1 (en) 2004-07-22
AU2003301263A1 (en) 2004-05-04
WO2004035005A2 (en) 2004-04-29

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8, 10, 11, 13 E 25 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.