MY167245A - Compounds and compositions as c-kit kinase inhibitors - Google Patents

Compounds and compositions as c-kit kinase inhibitors

Info

Publication number
MY167245A
MY167245A MYPI2014000347A MYPI2014000347A MY167245A MY 167245 A MY167245 A MY 167245A MY PI2014000347 A MYPI2014000347 A MY PI2014000347A MY PI2014000347 A MYPI2014000347 A MY PI2014000347A MY 167245 A MY167245 A MY 167245A
Authority
MY
Malaysia
Prior art keywords
compounds
kinase inhibitors
compositions
kit
kit kinase
Prior art date
Application number
MYPI2014000347A
Other languages
English (en)
Inventor
Vince Yeh
Xiaolin Li
Xiaodong Liu
Jon Loren
Valentina Molteni
Juliet Nabakka
Bao Nguyen
Hank Michael James Petrassi
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MY167245A publication Critical patent/MY167245A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
MYPI2014000347A 2011-09-01 2012-08-28 Compounds and compositions as c-kit kinase inhibitors MY167245A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161530028P 2011-09-01 2011-09-01

Publications (1)

Publication Number Publication Date
MY167245A true MY167245A (en) 2018-08-14

Family

ID=46829898

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2014000347A MY167245A (en) 2011-09-01 2012-08-28 Compounds and compositions as c-kit kinase inhibitors

Country Status (42)

Country Link
US (1) US9199981B2 (https=)
EP (1) EP2751102B1 (https=)
JP (1) JP6117208B2 (https=)
KR (1) KR101959590B1 (https=)
CN (1) CN103764653B (https=)
AP (1) AP2014007494A0 (https=)
AR (1) AR087752A1 (https=)
AU (1) AU2012300248B2 (https=)
BR (1) BR112014004504B1 (https=)
CA (1) CA2845159C (https=)
CL (1) CL2014000494A1 (https=)
CO (1) CO6900140A2 (https=)
CR (1) CR20140106A (https=)
CU (1) CU20140023A7 (https=)
CY (1) CY1121695T1 (https=)
DK (1) DK2751102T3 (https=)
EA (1) EA024293B1 (https=)
ES (1) ES2732671T3 (https=)
GT (1) GT201400036A (https=)
HR (1) HRP20191140T1 (https=)
HU (1) HUE044373T2 (https=)
IL (1) IL231226A (https=)
JO (1) JOP20120246B1 (https=)
LT (1) LT2751102T (https=)
MA (1) MA35459B1 (https=)
ME (1) ME03395B (https=)
MX (1) MX342329B (https=)
MY (1) MY167245A (https=)
PE (1) PE20141033A1 (https=)
PH (1) PH12014500351B1 (https=)
PL (1) PL2751102T3 (https=)
PT (1) PT2751102T (https=)
RS (1) RS59025B1 (https=)
SG (1) SG2014011050A (https=)
SI (1) SI2751102T1 (https=)
TN (1) TN2014000061A1 (https=)
TR (1) TR201909189T4 (https=)
TW (1) TWI543981B (https=)
UA (1) UA110841C2 (https=)
UY (1) UY34300A (https=)
WO (1) WO2013033070A1 (https=)
ZA (1) ZA201401113B (https=)

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WO2022016021A1 (en) * 2020-07-15 2022-01-20 Third Harmonic Bio, Inc. Crystalline forms of a selective c-kit kinase inhibitor
EP4247368A4 (en) * 2020-11-19 2024-10-23 Third Harmonic Bio, Inc. PHARMACEUTICAL COMPOSITIONS OF A SELECTIVE C-KIT KINASE INHIBITOR AND METHODS FOR THE PREPARATION AND USE THEREOF
US20220175740A1 (en) * 2020-11-19 2022-06-09 Novartis Ag Pharmaceutical compositions of a selective c-kit kinase inhibitor and methods for making and using same
WO2022182982A1 (en) * 2021-02-26 2022-09-01 Third Harmonic Bio, Inc. Methods for treating c-kit kinase mediated diseases and disorders using a selective c-kit kinase inhibitor
EP4308239A1 (en) 2021-03-16 2024-01-24 Janssen Sciences Ireland Unlimited Company Antibacterial compounds
CN117440958A (zh) * 2021-03-17 2024-01-23 爱尔兰詹森科学公司 抗菌化合物
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CN120659784A (zh) * 2022-12-07 2025-09-16 第三谐波生物股份有限公司 作为c-Kit激酶抑制剂的化合物和组合物
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WO2025256552A1 (zh) * 2024-06-11 2025-12-18 上海翰森生物医药科技有限公司 吡唑类衍生物抑制剂、其制备方法和应用
WO2025256609A1 (en) * 2024-06-13 2025-12-18 Third Harmonic Bio, Inc. Crystalline forms of a selective c-kit kinase inhibitor
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Also Published As

Publication number Publication date
PH12014500351A1 (en) 2014-04-07
UY34300A (es) 2013-04-05
JOP20120246B1 (ar) 2022-03-14
TR201909189T4 (tr) 2019-07-22
CA2845159C (en) 2020-11-03
SG2014011050A (en) 2014-08-28
SI2751102T1 (sl) 2019-08-30
EP2751102B1 (en) 2019-03-27
ZA201401113B (en) 2015-10-28
MX2014002482A (es) 2014-11-25
MA35459B1 (fr) 2014-09-01
ME03395B (me) 2020-01-20
AU2012300248A1 (en) 2014-04-17
AR087752A1 (es) 2014-04-16
LT2751102T (lt) 2019-07-10
AU2012300248B2 (en) 2015-08-27
US9199981B2 (en) 2015-12-01
DK2751102T3 (da) 2019-07-01
KR20140071382A (ko) 2014-06-11
TN2014000061A1 (en) 2015-07-01
HRP20191140T1 (hr) 2019-09-20
JP2014525444A (ja) 2014-09-29
CY1121695T1 (el) 2020-07-31
EA201490540A1 (ru) 2014-06-30
ES2732671T3 (es) 2019-11-25
BR112014004504B1 (pt) 2022-03-22
AP2014007494A0 (en) 2014-03-31
EA024293B1 (ru) 2016-09-30
EP2751102A1 (en) 2014-07-09
IL231226A0 (en) 2014-04-30
CN103764653B (zh) 2015-12-02
CR20140106A (es) 2014-05-02
NZ621092A (en) 2016-06-24
IL231226A (en) 2017-03-30
CN103764653A (zh) 2014-04-30
HUE044373T2 (hu) 2019-10-28
GT201400036A (es) 2015-06-02
TW201313716A (zh) 2013-04-01
MX342329B (es) 2016-09-26
BR112014004504A2 (pt) 2017-03-28
PH12014500351B1 (en) 2019-04-03
PT2751102T (pt) 2019-07-10
CA2845159A1 (en) 2013-03-07
PL2751102T3 (pl) 2019-09-30
CU20140023A7 (es) 2014-04-24
PE20141033A1 (es) 2014-08-30
KR101959590B1 (ko) 2019-03-18
UA110841C2 (uk) 2016-02-25
JP6117208B2 (ja) 2017-04-19
CO6900140A2 (es) 2014-03-20
RS59025B1 (sr) 2019-08-30
TWI543981B (zh) 2016-08-01
CL2014000494A1 (es) 2014-09-05
US20130059846A1 (en) 2013-03-07
WO2013033070A1 (en) 2013-03-07

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