EA201001331A1 - ГЕТЕРОЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ И СОДЕРЖАЩИЕ ИХ КОМПОЗИЦИИ В КАЧЕСТВЕ ИНГИБИТОРОВ КИНАЗ c-kit И PDGFR - Google Patents

ГЕТЕРОЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ И СОДЕРЖАЩИЕ ИХ КОМПОЗИЦИИ В КАЧЕСТВЕ ИНГИБИТОРОВ КИНАЗ c-kit И PDGFR

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Publication number
EA201001331A1
EA201001331A1 EA201001331A EA201001331A EA201001331A1 EA 201001331 A1 EA201001331 A1 EA 201001331A1 EA 201001331 A EA201001331 A EA 201001331A EA 201001331 A EA201001331 A EA 201001331A EA 201001331 A1 EA201001331 A1 EA 201001331A1
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EA
Eurasian Patent Office
Prior art keywords
kit
kinaz
pdgfr
inhibitors
compositions
Prior art date
Application number
EA201001331A
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English (en)
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EA018551B1 (ru
Inventor
Сяолинь ЛИ
Сяодон Лю
Джон Лорен
Валентина Мольтени
Джульет Набакка
Венс Йе
Донателла Кьянелли
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Айрм Ллк
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Application filed by Айрм Ллк filed Critical Айрм Ллк
Publication of EA201001331A1 publication Critical patent/EA201001331A1/ru
Publication of EA018551B1 publication Critical patent/EA018551B1/ru

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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Abstract

В заявке описаны новый класс соединений, фармацевтические композиции, содержащие такие соединения, и способы применения таких соединений для лечения или предупреждения заболеваний или нарушений, связанных с аномальной или характеризующейся нарушенной регуляцией активностью киназы, в особенности заболеваний или нарушений, которые включают аномальную активацию киназ c-kit, PDGFRα и PDGFRβ.
EA201001331A 2008-02-22 2009-02-20 ГЕТЕРОЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ И СОДЕРЖАЩИЕ ИХ КОМПОЗИЦИИ В КАЧЕСТВЕ ИНГИБИТОРОВ КИНАЗ c-KIT И PDGFR EA018551B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3091208P 2008-02-22 2008-02-22
PCT/US2009/034778 WO2009105712A1 (en) 2008-02-22 2009-02-20 Heterocyclic compounds and compositions as c-kit and pdgfr kinase inhibitors

Publications (2)

Publication Number Publication Date
EA201001331A1 true EA201001331A1 (ru) 2011-04-29
EA018551B1 EA018551B1 (ru) 2013-08-30

Family

ID=40577860

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201001331A EA018551B1 (ru) 2008-02-22 2009-02-20 ГЕТЕРОЦИКЛИЧЕСКИЕ СОЕДИНЕНИЯ И СОДЕРЖАЩИЕ ИХ КОМПОЗИЦИИ В КАЧЕСТВЕ ИНГИБИТОРОВ КИНАЗ c-KIT И PDGFR

Country Status (17)

Country Link
US (1) US8278452B2 (ru)
EP (1) EP2252612B1 (ru)
JP (1) JP5230755B2 (ru)
KR (1) KR101216323B1 (ru)
CN (1) CN102083828B (ru)
AR (1) AR070469A1 (ru)
AT (1) ATE551342T1 (ru)
AU (1) AU2009217356B2 (ru)
BR (1) BRPI0908849A2 (ru)
CA (1) CA2714700C (ru)
CL (1) CL2009000400A1 (ru)
EA (1) EA018551B1 (ru)
ES (1) ES2383331T3 (ru)
MX (1) MX2010009207A (ru)
PE (1) PE20091492A1 (ru)
TW (1) TW200940538A (ru)
WO (1) WO2009105712A1 (ru)

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