MXPA05009568A - Hidrolasas, acidos nucleicos que las codifican, y metodos para hacerlas y usarlas. - Google Patents
Hidrolasas, acidos nucleicos que las codifican, y metodos para hacerlas y usarlas.Info
- Publication number
- MXPA05009568A MXPA05009568A MXPA05009568A MXPA05009568A MXPA05009568A MX PA05009568 A MXPA05009568 A MX PA05009568A MX PA05009568 A MXPA05009568 A MX PA05009568A MX PA05009568 A MXPA05009568 A MX PA05009568A MX PA05009568 A MXPA05009568 A MX PA05009568A
- Authority
- MX
- Mexico
- Prior art keywords
- activity
- polypeptides
- hydrolase
- making
- polynucleotides
- Prior art date
Links
- 108090000604 Hydrolases Proteins 0.000 title abstract 6
- 102000004157 Hydrolases Human genes 0.000 title abstract 6
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 7
- 229920001184 polypeptide Polymers 0.000 abstract 6
- 102000040430 polynucleotide Human genes 0.000 abstract 4
- 108091033319 polynucleotide Proteins 0.000 abstract 4
- 239000002157 polynucleotide Substances 0.000 abstract 4
- ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 108090000371 Esterases Proteins 0.000 abstract 2
- 108091005804 Peptidases Proteins 0.000 abstract 2
- 108010064785 Phospholipases Proteins 0.000 abstract 2
- 102000015439 Phospholipases Human genes 0.000 abstract 2
- 239000004365 Protease Substances 0.000 abstract 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- 150000004665 fatty acids Chemical class 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- 108700023418 Amidases Proteins 0.000 abstract 1
- 108090001060 Lipase Proteins 0.000 abstract 1
- 102000004882 Lipase Human genes 0.000 abstract 1
- 239000004367 Lipase Substances 0.000 abstract 1
- 101710091688 Patatin Proteins 0.000 abstract 1
- 102000005922 amidase Human genes 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- -1 e.g. Proteins 0.000 abstract 1
- 235000021588 free fatty acids Nutrition 0.000 abstract 1
- 235000019421 lipase Nutrition 0.000 abstract 1
- 235000019626 lipase activity Nutrition 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002417 nutraceutical Substances 0.000 abstract 1
- 235000021436 nutraceutical agent Nutrition 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
- 150000003626 triacylglycerols Chemical class 0.000 abstract 1
Classifications
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- D06M—TREATMENT, NOT PROVIDED FOR ELSEWHERE IN CLASS D06, OF FIBRES, THREADS, YARNS, FABRICS, FEATHERS OR FIBROUS GOODS MADE FROM SUCH MATERIALS
- D06M2200/00—Functionality of the treatment composition and/or properties imparted to the textile material
- D06M2200/50—Modified hand or grip properties; Softening compositions
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
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Abstract
La invencion provee hidrolasas, polinucleotidos que las codifican, y metodos de hacer y usar estos polinucleotidos y polipeptidos. En un aspecto, la invencion esta dirigida a polipeptidos, v.gr., enzimas, que tienen una actividad de hidrolasa, v.gr., una actividad de esterasa, de acilasa, de lipasa, de fosfolipasa (v.gr., actividad de fosfolipasa A, B, C Y D), actividad de patalina, actividad de acil hidrolasa de lipido {LAH}, o actividad de proteasa, incluyendo actividad de hidrolasa termoestable y termotolerante, y polinucleotido que codifican estas enzimas, y hacer y usar estos polinucleotidos y polipeptidos. Las actividades de hidrolasa de los polipeptidos y los peptidos de la invencion incluyen actividad de esterasa, actividad de lipasa (hidrolisis de lipidos), reacciones de acidolisis (para reemplazar un acido graso esterificado con un acido graso libre), reacciones de trans-esterificacion (intercambio de acidos grasos entre trigliceridos), sintesis de esteres, reacciones de intercambio de esteres, actividad de fosfolipasa y actividad de proteasa (hidrolisis de enlaces peptidos). Los polipeptidos de la invencion pueden ser usados en una variedad de contextos farmaceuticos, agricolas e industriales, incluyendo la elaboracion de cosmeticos y nutraceuticos. En otro aspecto, los polipeptidos de la invencion son usados para sintetizar productos de quiral enantiomericamente puros.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US45345003P | 2003-03-07 | 2003-03-07 | |
US45812303P | 2003-03-24 | 2003-03-24 | |
US51333203P | 2003-10-21 | 2003-10-21 | |
PCT/US2004/007095 WO2005032496A2 (en) | 2003-03-07 | 2004-03-08 | Hydrolases, nucleic acids encoding them and mehods for making and using them |
Publications (2)
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MXPA05009568A true MXPA05009568A (es) | 2005-12-14 |
MX295545B MX295545B (es) | 2012-02-03 |
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ID=34426834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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MXPA05009568 MX295545B (es) | 2003-03-07 | 2004-03-08 | Hidrolasas, acidos nucleicos que las codifican, y metodos para hacerlas y usarlas. |
Country Status (9)
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US (3) | US8298799B2 (es) |
EP (3) | EP1601332A4 (es) |
JP (2) | JP4829105B2 (es) |
AU (2) | AU2004277368B2 (es) |
BR (1) | BRPI0408157B8 (es) |
CA (3) | CA2889013C (es) |
DK (1) | DK2853593T3 (es) |
MX (1) | MX295545B (es) |
WO (1) | WO2005032496A2 (es) |
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CA3007908A1 (en) | 2005-04-14 |
AU2011201719B2 (en) | 2012-10-11 |
BRPI0408157B8 (pt) | 2021-05-25 |
US20160060609A1 (en) | 2016-03-03 |
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CA2515583C (en) | 2015-07-14 |
AU2004277368A1 (en) | 2005-04-14 |
WO2005032496A2 (en) | 2005-04-14 |
US20070202566A1 (en) | 2007-08-30 |
CA2515583A1 (en) | 2005-04-14 |
MX295545B (es) | 2012-02-03 |
JP2010284168A (ja) | 2010-12-24 |
US9193962B2 (en) | 2015-11-24 |
CA2889013A1 (en) | 2005-04-14 |
BRPI0408157A (pt) | 2006-03-07 |
US10308920B2 (en) | 2019-06-04 |
EP2853593A1 (en) | 2015-04-01 |
WO2005032496A3 (en) | 2009-04-09 |
US20140128590A1 (en) | 2014-05-08 |
DK2853593T3 (en) | 2018-01-08 |
AU2011201719A1 (en) | 2011-05-12 |
BRPI0408157B1 (pt) | 2021-01-26 |
US8298799B2 (en) | 2012-10-30 |
JP4829105B2 (ja) | 2011-12-07 |
EP2853593B1 (en) | 2017-10-04 |
AU2004277368B2 (en) | 2011-01-20 |
CA2889013C (en) | 2018-07-17 |
EP3299465A1 (en) | 2018-03-28 |
EP1601332A2 (en) | 2005-12-07 |
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