MXPA05007843A - Composicion y tratamiento de enfermedades desmielinizantes y paralisis por administracion de agentes de remielinizantes. - Google Patents
Composicion y tratamiento de enfermedades desmielinizantes y paralisis por administracion de agentes de remielinizantes.Info
- Publication number
- MXPA05007843A MXPA05007843A MXPA05007843A MXPA05007843A MXPA05007843A MX PA05007843 A MXPA05007843 A MX PA05007843A MX PA05007843 A MXPA05007843 A MX PA05007843A MX PA05007843 A MXPA05007843 A MX PA05007843A MX PA05007843 A MXPA05007843 A MX PA05007843A
- Authority
- MX
- Mexico
- Prior art keywords
- demyelination
- paralysis
- compositions
- administration
- treatment
- Prior art date
Links
- 208000016192 Demyelinating disease Diseases 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 206010033799 Paralysis Diseases 0.000 title abstract 2
- 206010012305 Demyelination Diseases 0.000 abstract 3
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- -1 antibodies Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 229940072221 immunoglobulins Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 102000006495 integrins Human genes 0.000 abstract 1
- 108010044426 integrins Proteins 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44217103P | 2003-01-24 | 2003-01-24 | |
| US50031603P | 2003-09-05 | 2003-09-05 | |
| PCT/US2004/002039 WO2004066932A2 (en) | 2003-01-24 | 2004-01-26 | Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA05007843A true MXPA05007843A (es) | 2005-10-18 |
Family
ID=32829779
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05007843A MXPA05007843A (es) | 2003-01-24 | 2004-01-26 | Composicion y tratamiento de enfermedades desmielinizantes y paralisis por administracion de agentes de remielinizantes. |
| MXPA05007823A MXPA05007823A (es) | 2003-01-24 | 2004-01-26 | Composicion y tratamiento de enfermedades desmielizantes y paralisis por administracion de agentes remielinizantes. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA05007823A MXPA05007823A (es) | 2003-01-24 | 2004-01-26 | Composicion y tratamiento de enfermedades desmielizantes y paralisis por administracion de agentes remielinizantes. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20050069541A1 (enExample) |
| EP (4) | EP1592387A4 (enExample) |
| JP (4) | JP2007521249A (enExample) |
| KR (2) | KR101260497B1 (enExample) |
| AU (5) | AU2004207535A1 (enExample) |
| CA (2) | CA2514125A1 (enExample) |
| CO (1) | CO5670359A2 (enExample) |
| IL (1) | IL169770A (enExample) |
| MX (2) | MXPA05007843A (enExample) |
| NO (1) | NO20053920L (enExample) |
| PE (1) | PE20040942A1 (enExample) |
| RU (1) | RU2412721C2 (enExample) |
| SK (1) | SK50642005A3 (enExample) |
| TW (2) | TWI428141B (enExample) |
| UY (1) | UY28170A1 (enExample) |
| WO (2) | WO2004066931A2 (enExample) |
Families Citing this family (45)
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| US7368421B2 (en) | 2001-06-27 | 2008-05-06 | Probiodrug Ag | Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis |
| KR20040105740A (ko) * | 2002-02-25 | 2004-12-16 | 엘란 파마슈티칼스, 인크. | 염증 치료제의 투여 방법 |
| JP2007521249A (ja) | 2003-01-24 | 2007-08-02 | エラン ファーマシューティカルズ，インコーポレイテッド | 脱髄疾患および麻痺のための組成物ならびに再有髄化剤を投与することによるそれらの治療 |
| EP1706399A1 (en) * | 2004-01-23 | 2006-10-04 | Elan Pharmaceuticals, Inc. | Polyethylene glycol conjugates of heterocycloalkyl carboxamido propanoic acids |
| MY162179A (en) | 2004-04-01 | 2017-05-31 | Elan Pharm Inc | Steroid sparing agents and methods of using same |
| CA2573245C (en) | 2004-07-08 | 2013-10-01 | Elan Pharmaceuticals, Inc. | Multivalent vla-4 antagonists comprising polymer moieties |
| CA2478458A1 (en) * | 2004-08-20 | 2006-02-20 | Michael Panzara | Treatment of pediatric multiple sclerosis |
| CA2587597A1 (en) * | 2004-11-19 | 2006-05-26 | Biogen Idec Ma Inc. | Treatment for multiple sclerosis |
| NZ581497A (en) * | 2004-12-03 | 2012-07-27 | Biogen Idec Inc | Delaying or preventing onset of multiple sclerosis by vla-4 ginding antibody |
| CA2606081C (en) | 2005-04-26 | 2013-09-17 | Markus M. Heiss | Combination of the application of antibodies for immunostimulation together with glucocorticoids |
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| US9008378B2 (en) * | 2006-12-20 | 2015-04-14 | The Board Of Trustees Of The Leland Stanford Junior University | Arrangement and imaging of biological samples |
| EP2198040B1 (en) * | 2007-08-31 | 2018-08-15 | Case Western Reserve University | In vivo imaging of myelin |
| US9040715B2 (en) * | 2008-09-23 | 2015-05-26 | Georgetown University | 1,2-benzisothiazolinone and isoindolinone derivatives |
| MX2011010971A (es) * | 2009-04-17 | 2012-01-19 | Biogen Idec Inc | Composiciones y metodos para tratar leucemia mielogena aguda. |
| EP2467159A1 (en) * | 2009-08-20 | 2012-06-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vla-4 as a biomarker for prognosis and target for therapy in duchenne muscular dystrophy |
| ES2912934T3 (es) | 2010-04-16 | 2022-05-30 | Biogen Ma Inc | Anticuerpos anti VLA-4 |
| US20130190299A1 (en) * | 2010-06-30 | 2013-07-25 | Victoria Link Ltd. | Methods and compositions for treatment of multiple sclerosis |
| EP3722808B1 (en) | 2010-10-25 | 2024-09-11 | Biogen MA Inc. | Methods for determining differences in alpha-4 integrin activity by correlating differences in svcam and/or smadcam levels |
| MX361929B (es) * | 2010-11-19 | 2018-12-19 | Eisai R&D Man Co Ltd Star | Anticuerpos anti-ligando de quimiocina cc 20 (ccl20) neutralizantes. |
| WO2013025897A1 (en) | 2011-08-16 | 2013-02-21 | Georgetown University | Methods of treating bacterial infections with 1,2-benzisothiazolinone and isoindolinone derivatives |
| FI3590960T3 (fi) | 2012-02-29 | 2023-04-25 | Takeda Pharmaceuticals Co | Perifeeristen hermojen IgG-stimuloitu remyelinaatio |
| TWI595007B (zh) | 2012-09-10 | 2017-08-11 | Neotope Biosciences Ltd | 抗ｍｃａｍ抗體及相關使用方法 |
| MX2015004436A (es) * | 2012-10-09 | 2015-06-24 | Biogen Idec Inc | Tratamientos conjuntos y usos para tratar trastornos desmielinizantes. |
| AU2014324426A1 (en) | 2013-09-30 | 2016-04-21 | The Regents Of The University Of California | Anti-alphavbeta1 integrin compounds and methods |
| PT3116911T (pt) | 2014-03-12 | 2019-09-04 | Prothena Biosciences Ltd | Anticorpos anti-mcam e métodos de utilização associados |
| WO2015136472A1 (en) | 2014-03-12 | 2015-09-17 | Prothena Biosciences Limited | Anti-laminin4 antibodies specific for lg4-5 |
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| KR102364840B1 (ko) | 2014-11-05 | 2022-02-18 | 삼성전자주식회사 | 신경세포의 탈수초화와 연관된 질환을 치료하기 위한 약학적 조성물 및 그를 이용하는 방법 |
| BR112017012365A2 (pt) * | 2014-12-12 | 2018-04-24 | Commw Scient Ind Res Org | desalojamento e liberação de hsc do nicho de célula-tronco da medula óssea usando antagonistas de alfa-9-integrina. |
| US10738121B2 (en) | 2015-02-27 | 2020-08-11 | The General Hospital Corporation | Therapeutic use of integrin-binding antibodies |
| AU2016228852A1 (en) | 2015-03-10 | 2017-10-19 | The Regents Of The University Of California | Anti-alphavbeta1 integrin inhibitors and methods of use |
| CN106316982B (zh) * | 2015-06-30 | 2020-08-14 | 中国人民解放军军事医学科学院毒物药物研究所 | 噻嗪酰胺衍生物及其用途 |
| US10947311B2 (en) * | 2015-11-20 | 2021-03-16 | The Board Of Trustees Of The Leland Stanford Junior University | VCAM-1 mediated methods and compositions for treating aging-associated impairments |
| KR102898678B1 (ko) * | 2018-05-23 | 2025-12-12 | 체에스엘 베링 아게 | Cidp의 치료 |
| CN112867394B9 (zh) | 2018-06-04 | 2024-12-06 | 马萨诸塞州渤健公司 | 具有降低的效应功能的抗vla-4抗体 |
| WO2020092401A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | COMPOUNDS FOR INHIBITION OF ALPHA 4β7 INTEGRIN |
| WO2020092394A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
| DK3873884T3 (da) | 2018-10-30 | 2025-02-17 | Gilead Sciences Inc | 3-(quinolin-8-yl)-1,4-dihydropyrido[3,4-d]pyrimidin-2,4-dion-derivater som alpha4beta7-integrinhæmmere til behandling af inflammatoriske sygdomme |
| ES2987796T3 (es) | 2018-10-30 | 2024-11-18 | Gilead Sciences Inc | Derivados de N-benzoil-fenilalanina como inhibidores de la integrina alfa4beta7 para el tratamiento de enfermedades inflamatorias |
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2004
- 2004-01-26 JP JP2006503001A patent/JP2007521249A/ja active Pending
- 2004-01-26 SK SK5064-2005A patent/SK50642005A3/sk not_active Application Discontinuation
- 2004-01-26 EP EP04705270A patent/EP1592387A4/en not_active Withdrawn
- 2004-01-26 AU AU2004207535A patent/AU2004207535A1/en not_active Abandoned
- 2004-01-26 PE PE2004000100A patent/PE20040942A1/es not_active Application Discontinuation
- 2004-01-26 AU AU2004207536A patent/AU2004207536B2/en not_active Expired - Fee Related
- 2004-01-26 US US10/763,424 patent/US20050069541A1/en not_active Abandoned
- 2004-01-26 EP EP04705266A patent/EP1592386A4/en not_active Withdrawn
- 2004-01-26 CA CA002514125A patent/CA2514125A1/en not_active Abandoned
- 2004-01-26 KR KR1020127024847A patent/KR101260497B1/ko not_active Expired - Lifetime
- 2004-01-26 EP EP11008463A patent/EP2484381A1/en not_active Withdrawn
- 2004-01-26 CA CA002514117A patent/CA2514117A1/en not_active Abandoned
- 2004-01-26 MX MXPA05007843A patent/MXPA05007843A/es unknown
- 2004-01-26 KR KR1020057013695A patent/KR20050114212A/ko not_active Ceased
- 2004-01-26 MX MXPA05007823A patent/MXPA05007823A/es not_active Application Discontinuation
- 2004-01-26 US US10/763,539 patent/US7576101B2/en active Active
- 2004-01-26 WO PCT/US2004/002028 patent/WO2004066931A2/en not_active Ceased
- 2004-01-26 EP EP19152970.0A patent/EP3527228A1/en not_active Withdrawn
- 2004-01-26 WO PCT/US2004/002039 patent/WO2004066932A2/en not_active Ceased
- 2004-01-26 UY UY28170A patent/UY28170A1/es not_active Application Discontinuation
- 2004-01-26 JP JP2006502997A patent/JP2006516624A/ja active Pending
- 2004-01-26 RU RU2005126728/15A patent/RU2412721C2/ru active
- 2004-01-27 TW TW093101747A patent/TWI428141B/zh not_active IP Right Cessation
- 2004-01-27 TW TW101146999A patent/TW201311238A/zh unknown
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2005
- 2005-07-19 IL IL169770A patent/IL169770A/en active IP Right Grant
- 2005-08-23 NO NO20053920A patent/NO20053920L/no not_active Application Discontinuation
- 2005-08-24 CO CO05084319A patent/CO5670359A2/es not_active Application Discontinuation
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2010
- 2010-04-14 AU AU2010201472A patent/AU2010201472A1/en not_active Abandoned
- 2010-08-19 AU AU2010212446A patent/AU2010212446B2/en not_active Expired
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2011
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