MXPA04001606A - Amilopectina hiperramificada para usarla en metodos para el tratamiento quirurgico o terapeutico de mamiferos o en metodos de diagnostico, especialmente para usarla como un expansor de volumen de plasma. - Google Patents
Amilopectina hiperramificada para usarla en metodos para el tratamiento quirurgico o terapeutico de mamiferos o en metodos de diagnostico, especialmente para usarla como un expansor de volumen de plasma.Info
- Publication number
- MXPA04001606A MXPA04001606A MXPA04001606A MXPA04001606A MXPA04001606A MX PA04001606 A MXPA04001606 A MX PA04001606A MX PA04001606 A MXPA04001606 A MX PA04001606A MX PA04001606 A MXPA04001606 A MX PA04001606A MX PA04001606 A MXPA04001606 A MX PA04001606A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- amylopectin
- plasma volume
- surgical
- plasma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/20—Amylose or amylopectin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B35/00—Preparation of derivatives of amylopectin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Environmental Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invencion se refiere al uso de amilopectina hiperramificada que tiene un grado de ramificacion promedio de entre > 10 y 25% molar y un peso molecular (Pm) que varia de 40,000-800,000 Dalton, y derivados de la misma en metodos para el tratamiento quirurgico o terapeutico de cuerpos humanos o animales o en un metodo de diagnostico, de preferencia como un expansor del volumen de plasma; los expansores del volumen de plasma que se basan en la amilopectina hidroxi-etilada han exhibido hasta ahora, como resultado de la hidroxietilacion, la desventaja de un metabolismo incompleto y por lo tanto el almacenamiento temporal en el tejido que esta ligado con los efectos laterales; de acuerdo con la invencion, se proporcionan expansores novedosos de plasma basados en polisacaridos que no exhiben las mismas desventajas que los anteriores; se proporcionan expansores de plasma completamente metabolizados, mejorados, que estan basados en amilopectina hiperramificada, los cuales se pueden obtener a partir de la misma, de manera que las amilopectinas vegetales naturales se alteran mediante la transglicolisacion, de modo que el alto grado de ramificacion ajustable hace posible el control de la descomposicion de la suero-a-amilasa, de manera que no es necesaria, o es necesaria solo en un grado muy insignificante, la hidroxi-etilacion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10141099 | 2001-08-22 | ||
| PCT/EP2002/008757 WO2003018639A1 (de) | 2001-08-22 | 2002-08-06 | Hyperverzweigtes amylopektin zum einsatz in verfahren zur chirurgischen oder therapeutischen behandlung von säugern oder in diagnostizierverfahren, insbesondere zur verwendung als plasmavolumenexpander |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04001606A true MXPA04001606A (es) | 2005-03-07 |
Family
ID=7696220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04001606A MXPA04001606A (es) | 2001-08-22 | 2002-08-06 | Amilopectina hiperramificada para usarla en metodos para el tratamiento quirurgico o terapeutico de mamiferos o en metodos de diagnostico, especialmente para usarla como un expansor de volumen de plasma. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7393841B2 (es) |
| EP (1) | EP1421120B1 (es) |
| JP (1) | JP2005501930A (es) |
| KR (1) | KR100898528B1 (es) |
| CN (1) | CN100390203C (es) |
| AT (1) | ATE360651T1 (es) |
| AU (1) | AU2002325398B2 (es) |
| CA (1) | CA2456507C (es) |
| DE (2) | DE50210039D1 (es) |
| DK (1) | DK1421120T3 (es) |
| ES (1) | ES2283585T3 (es) |
| HK (1) | HK1068356A1 (es) |
| HU (1) | HUP0401188A3 (es) |
| MX (1) | MXPA04001606A (es) |
| PL (1) | PL209763B1 (es) |
| PT (1) | PT1421120E (es) |
| RO (1) | RO122279B1 (es) |
| RS (1) | RS51420B (es) |
| RU (1) | RU2303984C2 (es) |
| WO (1) | WO2003018639A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2840612B1 (fr) * | 2002-06-06 | 2005-05-06 | Roquette Freres | Polymeres solubles de glucose hautement branches et leur procede d'obtention |
| DE10237442B4 (de) * | 2002-08-16 | 2004-08-19 | Fresenius Kabi Deutschland Gmbh | Hochverzweigte, niedrig substituierte Stärkeprodukte |
| DE10256558A1 (de) * | 2002-12-04 | 2004-09-16 | Supramol Parenteral Colloids Gmbh | Ester von Polysaccharid Aldonsäuren, Verfahren zu ihrer Herstellung und Verwendung zur Kopplung an pharmazeutische Wirkstoffe |
| CZ20033424A3 (cs) * | 2003-12-16 | 2005-08-17 | Parenteral, A. S. | Náhražka krevní plazmy, výchozí produkt a způsob výroby výchozího produktu pro náhražku lidské krevní plazmy |
| FR2864088B1 (fr) | 2003-12-19 | 2006-04-28 | Roquette Freres | Polymeres solubles de glucose hautement branches |
| ATE540996T1 (de) | 2005-06-06 | 2012-01-15 | Univ British Columbia | Polymerbasierter serumalbumin-ersatzstoff |
| EP1943908A1 (en) * | 2006-12-29 | 2008-07-16 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Novel slowly digestible storage carbohydrate |
| CN102906157B (zh) | 2010-03-01 | 2016-08-24 | 不列颠哥伦比亚大学 | 衍生的超支化聚丙三醇 |
| CN103140503B (zh) * | 2010-06-17 | 2016-05-18 | 株式会社林原 | 含有支链淀粉的粉末及其制备方法以及用途 |
| AR095937A1 (es) * | 2013-04-05 | 2015-11-25 | Acraf | Potenciador de la solubilidad en agua a base de glucógeno |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA928215A (en) * | 1969-08-08 | 1973-06-12 | M. Brake Jon | Process for the cryogenic preservation of blood and erythrocytes and products produced thereby |
| US4125492A (en) | 1974-05-31 | 1978-11-14 | Pedro Cuatrecasas | Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers |
| US4111199A (en) * | 1977-03-31 | 1978-09-05 | Isaac Djerassi | Method of collecting transfusable granulocytes by gravity leukopheresis |
| DE3029307A1 (de) | 1980-08-01 | 1982-03-04 | Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG, 6380 Bad Homburg | Haemoglobin enthaltendes blutersatzmittel |
| US4454161A (en) * | 1981-02-07 | 1984-06-12 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Process for the production of branching enzyme, and a method for improving the qualities of food products therewith |
| DE3313600A1 (de) * | 1983-04-14 | 1984-10-18 | Laevosan-Gesellschaft mbH & Co. KG, Linz | Plasmastreckmittel auf staerkebasis und verfahren zu ihrer herstellung |
| NL8902128A (nl) * | 1989-08-23 | 1991-03-18 | Avebe Coop Verkoop Prod | Vertakkingsenzym en gebruik daarvan. |
| JP2896580B2 (ja) | 1989-08-25 | 1999-05-31 | チッソ株式会社 | アミロース―リゾチームハイブリッドと活性化糖およびその製造法 |
| DE19628705A1 (de) | 1996-07-08 | 1998-01-15 | Fresenius Ag | Neue Sauerstoff-Transport-Mittel, diese enthaltende Hämoglobin-Hydroxyethylstärke-Konjugate, Verfahren zu deren Herstellung, sowie deren Verwendung als Blutersatzstoffe |
| FR2783838B1 (fr) | 1998-09-25 | 2000-12-01 | Roquette Freres | Procede de preparation d'un melange d'enzymes de branchement de l'amidon extraites d'algues |
| AT409928B (de) * | 1999-08-10 | 2002-12-27 | Tulln Zuckerforschung Gmbh | Plasmaexpander, blutverdünnungsmittel und kryoprotektor, hergestellt unter verwendung von amylopektin-kartoffelstärke |
| JP2001294601A (ja) | 2000-04-11 | 2001-10-23 | Akita Prefecture | 高度分岐澱粉と該高度分岐澱粉の製造方法 |
| DE10112825A1 (de) | 2001-03-16 | 2002-10-02 | Fresenius Kabi De Gmbh | HESylierung von Wirkstoffen in wässriger Lösung |
-
2002
- 2002-08-06 DE DE50210039T patent/DE50210039D1/de not_active Expired - Lifetime
- 2002-08-06 MX MXPA04001606A patent/MXPA04001606A/es active IP Right Grant
- 2002-08-06 DE DE10235954A patent/DE10235954A1/de not_active Withdrawn
- 2002-08-06 CA CA2456507A patent/CA2456507C/en not_active Expired - Fee Related
- 2002-08-06 PL PL369363A patent/PL209763B1/pl not_active IP Right Cessation
- 2002-08-06 RU RU2004108122/15A patent/RU2303984C2/ru not_active IP Right Cessation
- 2002-08-06 JP JP2003523498A patent/JP2005501930A/ja active Pending
- 2002-08-06 AT AT02758435T patent/ATE360651T1/de active
- 2002-08-06 ES ES02758435T patent/ES2283585T3/es not_active Expired - Lifetime
- 2002-08-06 RO ROA200400154A patent/RO122279B1/ro unknown
- 2002-08-06 HU HU0401188A patent/HUP0401188A3/hu unknown
- 2002-08-06 WO PCT/EP2002/008757 patent/WO2003018639A1/de active IP Right Grant
- 2002-08-06 US US10/486,943 patent/US7393841B2/en not_active Expired - Fee Related
- 2002-08-06 KR KR10-2004-7002536A patent/KR100898528B1/ko not_active IP Right Cessation
- 2002-08-06 RS YUP-147/04A patent/RS51420B/en unknown
- 2002-08-06 DK DK02758435T patent/DK1421120T3/da active
- 2002-08-06 AU AU2002325398A patent/AU2002325398B2/en not_active Ceased
- 2002-08-06 CN CNB028163540A patent/CN100390203C/zh not_active Expired - Fee Related
- 2002-08-06 EP EP02758435A patent/EP1421120B1/de not_active Expired - Lifetime
- 2002-08-06 PT PT02758435T patent/PT1421120E/pt unknown
-
2005
- 2005-01-17 HK HK05100431A patent/HK1068356A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK1421120T3 (da) | 2007-09-17 |
| PL369363A1 (en) | 2005-04-18 |
| RU2303984C2 (ru) | 2007-08-10 |
| CA2456507A1 (en) | 2003-03-06 |
| ATE360651T1 (de) | 2007-05-15 |
| AU2002325398B2 (en) | 2008-02-28 |
| EP1421120B1 (de) | 2007-04-25 |
| JP2005501930A (ja) | 2005-01-20 |
| ES2283585T3 (es) | 2007-11-01 |
| HUP0401188A2 (hu) | 2004-09-28 |
| CN1545522A (zh) | 2004-11-10 |
| HK1068356A1 (en) | 2005-04-29 |
| CN100390203C (zh) | 2008-05-28 |
| EP1421120A1 (de) | 2004-05-26 |
| KR100898528B1 (ko) | 2009-05-20 |
| US20040157207A1 (en) | 2004-08-12 |
| RS14704A (en) | 2007-02-05 |
| DE10235954A1 (de) | 2003-03-06 |
| RO122279B1 (ro) | 2009-03-30 |
| RU2004108122A (ru) | 2005-03-27 |
| WO2003018639A1 (de) | 2003-03-06 |
| HUP0401188A3 (en) | 2012-09-28 |
| DE50210039D1 (de) | 2007-06-06 |
| RS51420B (en) | 2011-02-28 |
| CA2456507C (en) | 2011-05-03 |
| KR20040052215A (ko) | 2004-06-22 |
| US7393841B2 (en) | 2008-07-01 |
| PL209763B1 (pl) | 2011-10-31 |
| PT1421120E (pt) | 2007-08-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1068356A1 (en) | Hyperbranched amylopectin for use in methods for surgical or therapeutic treatment of mammals or in diagnostic methods | |
| WO1997029779A3 (en) | EGF-Genistein conjugates for the treatment of cancer | |
| UA66857C2 (uk) | КОН'ЮГАТ ПОЛІОЛ-<font face="Symbol">b</font>-ІНТЕРФЕРОН, СПОСІБ ОДЕРЖАННЯ КОН'ЮГАТУ ПОЛІОЛ-<font face="Symbol">b</font>-ІНТЕРФЕРОН ТА СПОСІБ ЛІКУВАННЯ ІНФЕКЦІЙНИХ ХВОРОБ, ПУХЛИН І АУТОІМУННИХ І ЗАПАЛЬНИХ ЗАХВОРЮВАНЬ | |
| WO2003022210A3 (en) | Pharmaceutical compositions of drug-oligomer conjugates and methods of treating diseases therewith | |
| DE69925830D1 (de) | Peg-lhrh analog konjugate | |
| EP2292649A3 (en) | Therapeutic epitopes and uses thereof | |
| WO2003002022A3 (en) | Minimally invasive orthopaedic apparatus and methods | |
| WO2000051662A9 (en) | Bioabsorbable, biocompatible polymers for tissue engineering | |
| WO2004039248A3 (en) | Repairing or replacing tissues or organs | |
| HUP0101189A2 (hu) | Vas-dextrán vegyület felhasználása vashiány megelőzésére és kezelésére szolgáló gyógyszerkészítmény alkotórészeként, eljárás a nevezett vas-dextrán vegyület előállítására, és a nevezett vegyület felhasználása parenterálisan beadható gyógyszerkészítmény... | |
| WO2001038303A3 (fr) | Analogues de la vitamine d | |
| EP2258702A3 (en) | Purified compositions of 10-Propargyl-10-Deazaaminopterin and method of using same in the treatment of tumors | |
| WO2003106384A3 (en) | NOVEL BORIC CHALCONE DERIVATIVES AND USES THEREOF | |
| BR0111506A (pt) | Complexos de droga macromoleculares e composições contendo os mesmos | |
| WO2002102743A3 (de) | Deuterierte n- und alpha-substituierte diphenylalkoyxessigsäureaminoalkylester sowie diese verbindungen enthaltende arzneimittel | |
| EP2191839A3 (en) | Immunogenic LHRH compositions and methods relating thereto | |
| WO2001005408A8 (en) | Fat-binding polymers, optionally combined with lipase inhibitors | |
| ATE237349T1 (en) | Fat-binding polymers | |
| WO2003103614A3 (en) | METHOD AND COMPOSITIONS FOR THE TREATMENT OF OEDEMATUS FIBROSCLEREUS PANNICULOPATHY | |
| AU2002319223A1 (en) | Medicament for treating tumours and their metastases using a binding molecule against bone-sialoprotein | |
| MXPA02000052A (es) | Metodos y composiciones para el soporte, regeneracion y reparacion de tejidos conectivos. | |
| EP4215060A1 (en) | Process for preparation of a controlled-release system | |
| AU2001276437A1 (en) | Use of polysulphated cyclodextrins for treating osteoarthritis | |
| WO2004075977A3 (en) | Methods using diffuse field ultrasound-induced hyperthermia | |
| Dubey et al. | Immediate placement of dental implants in non vascularised iliac graft after resection of anterior mandible: A case report |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |