MXPA03009938A - Pirimidinas fusionadas como antagonistas del factor liberador de corticotropina. - Google Patents

Pirimidinas fusionadas como antagonistas del factor liberador de corticotropina.

Info

Publication number
MXPA03009938A
MXPA03009938A MXPA03009938A MXPA03009938A MXPA03009938A MX PA03009938 A MXPA03009938 A MX PA03009938A MX PA03009938 A MXPA03009938 A MX PA03009938A MX PA03009938 A MXPA03009938 A MX PA03009938A MX PA03009938 A MXPA03009938 A MX PA03009938A
Authority
MX
Mexico
Prior art keywords
methyl
dihydro
pyrrolo
dichlorophenyl
pyrimidine
Prior art date
Application number
MXPA03009938A
Other languages
English (en)
Spanish (es)
Inventor
Perini Benedetta
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0110569A external-priority patent/GB0110569D0/en
Priority claimed from GB0110567A external-priority patent/GB0110567D0/en
Priority claimed from GB0110570A external-priority patent/GB0110570D0/en
Priority claimed from GB0117420A external-priority patent/GB0117420D0/en
Priority claimed from GB0117401A external-priority patent/GB0117401D0/en
Priority claimed from GB0117399A external-priority patent/GB0117399D0/en
Priority claimed from GB0203201A external-priority patent/GB0203201D0/en
Priority claimed from GB0206834A external-priority patent/GB0206834D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MXPA03009938A publication Critical patent/MXPA03009938A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
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    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0463—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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    • A61K51/0465—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
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    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
MXPA03009938A 2001-04-30 2002-04-30 Pirimidinas fusionadas como antagonistas del factor liberador de corticotropina. MXPA03009938A (es)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB0110569A GB0110569D0 (en) 2001-04-30 2001-04-30 Chemical compounds
GB0110567A GB0110567D0 (en) 2001-04-30 2001-04-30 Chemical compounds
GB0110570A GB0110570D0 (en) 2001-04-30 2001-04-30 Chemical compounds
GB0117420A GB0117420D0 (en) 2001-07-17 2001-07-17 Chemical compounds
GB0117401A GB0117401D0 (en) 2001-07-17 2001-07-17 Chemical compounds
GB0117399A GB0117399D0 (en) 2001-07-17 2001-07-17 Chemical compounds
GB0203201A GB0203201D0 (en) 2002-02-11 2002-02-11 Chemical compounds
GB0206834A GB0206834D0 (en) 2002-03-22 2002-03-22 Chemical compounds
PCT/GB2002/002029 WO2002088095A1 (en) 2001-04-30 2002-04-30 Fused pyrimidines as antagonists of the corticotropin releasing factor (crf)

Publications (1)

Publication Number Publication Date
MXPA03009938A true MXPA03009938A (es) 2005-09-07

Family

ID=27571152

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03009938A MXPA03009938A (es) 2001-04-30 2002-04-30 Pirimidinas fusionadas como antagonistas del factor liberador de corticotropina.

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EP (1) EP1383747B1 (US20040176400A1-20040909-C00159.png)
JP (1) JP2004528349A (US20040176400A1-20040909-C00159.png)
KR (1) KR20040015206A (US20040176400A1-20040909-C00159.png)
CN (1) CN1649848A (US20040176400A1-20040909-C00159.png)
AR (1) AR033295A1 (US20040176400A1-20040909-C00159.png)
AT (1) ATE386727T1 (US20040176400A1-20040909-C00159.png)
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BR (1) BR0209267A (US20040176400A1-20040909-C00159.png)
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IL (1) IL158062A0 (US20040176400A1-20040909-C00159.png)
MX (1) MXPA03009938A (US20040176400A1-20040909-C00159.png)
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PL (1) PL366934A1 (US20040176400A1-20040909-C00159.png)
WO (1) WO2002088095A1 (US20040176400A1-20040909-C00159.png)

Families Citing this family (61)

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Publication number Priority date Publication date Assignee Title
DE60226971D1 (de) * 2001-06-12 2008-07-17 Glaxo Group Ltd Corticotropinfreisetzungsfaktor antagonisten
GB0117396D0 (en) * 2001-07-17 2001-09-05 Glaxo Group Ltd Chemical compounds
ATE359782T1 (de) * 2003-01-16 2007-05-15 Sb Pharmco Inc Heteroaryl-substituierte pyrrol(2, 3- b)pyridin- derivate als crf-rezeptor-antagonisten
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
GB0308208D0 (en) * 2003-04-09 2003-05-14 Glaxo Group Ltd Chemical compounds
BRPI0409986A (pt) * 2003-05-05 2006-05-09 Hoffmann La Roche derivados de pirimidina fundida com atividade de crf
CA2535249A1 (en) 2003-08-12 2005-02-17 F. Hoffmann-La Roche Ag Spiro-substituted tetrahydroquinazolines as corticotropin releasing factor (cfr) antagonists
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