MXPA01011562A - Composiciones y usos de et743 para tratar cancer. - Google Patents

Composiciones y usos de et743 para tratar cancer.

Info

Publication number
MXPA01011562A
MXPA01011562A MXPA01011562A MXPA01011562A MXPA01011562A MX PA01011562 A MXPA01011562 A MX PA01011562A MX PA01011562 A MXPA01011562 A MX PA01011562A MX PA01011562 A MXPA01011562 A MX PA01011562A MX PA01011562 A MXPA01011562 A MX PA01011562A
Authority
MX
Mexico
Prior art keywords
cancer
patients
comprises administering
human patient
treating
Prior art date
Application number
MXPA01011562A
Other languages
English (en)
Spanish (es)
Inventor
Hoff Daniel D Von
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9911183.3A external-priority patent/GB9911183D0/en
Priority claimed from GBGB9911346.6A external-priority patent/GB9911346D0/en
Priority claimed from GBGB9918534.0A external-priority patent/GB9918534D0/en
Priority claimed from GBGB9927005.0A external-priority patent/GB9927005D0/en
Priority claimed from GBGB9927106.6A external-priority patent/GB9927106D0/en
Priority claimed from GB0007637A external-priority patent/GB0007637D0/en
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Publication of MXPA01011562A publication Critical patent/MXPA01011562A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995Pyrazines or piperazines forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
MXPA01011562A 1999-05-13 2000-05-15 Composiciones y usos de et743 para tratar cancer. MXPA01011562A (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9911183.3A GB9911183D0 (en) 1999-05-13 1999-05-13 Treatment of cancers
GBGB9911346.6A GB9911346D0 (en) 1999-05-14 1999-05-14 Treatment of cancers
GBGB9918534.0A GB9918534D0 (en) 1999-08-05 1999-08-05 Treatment of cancers
GBGB9927005.0A GB9927005D0 (en) 1999-11-15 1999-11-15 Treatment of cancers
GBGB9927106.6A GB9927106D0 (en) 1999-11-16 1999-11-16 Cancer treatment
GB0007637A GB0007637D0 (en) 2000-03-29 2000-03-29 Antitumour compound
PCT/GB2000/001857 WO2000069441A1 (en) 1999-05-13 2000-05-15 Compositions and uses of et743 for treating cancer

Publications (1)

Publication Number Publication Date
MXPA01011562A true MXPA01011562A (es) 2002-07-30

Family

ID=27546594

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01011562A MXPA01011562A (es) 1999-05-13 2000-05-15 Composiciones y usos de et743 para tratar cancer.

Country Status (32)

Country Link
US (1) US8119638B2 (cg-RX-API-DMAC7.html)
EP (3) EP1702618B1 (cg-RX-API-DMAC7.html)
JP (2) JP2002544231A (cg-RX-API-DMAC7.html)
KR (1) KR20020019914A (cg-RX-API-DMAC7.html)
CN (2) CN1360503A (cg-RX-API-DMAC7.html)
AR (1) AR028476A1 (cg-RX-API-DMAC7.html)
AT (3) ATE338552T1 (cg-RX-API-DMAC7.html)
AU (2) AU777417B2 (cg-RX-API-DMAC7.html)
BG (1) BG65680B1 (cg-RX-API-DMAC7.html)
BR (1) BR0010531A (cg-RX-API-DMAC7.html)
CA (1) CA2373794C (cg-RX-API-DMAC7.html)
CY (4) CY1105818T1 (cg-RX-API-DMAC7.html)
CZ (1) CZ301482B6 (cg-RX-API-DMAC7.html)
DE (4) DE122008000013I1 (cg-RX-API-DMAC7.html)
DK (3) DK1176964T3 (cg-RX-API-DMAC7.html)
ES (2) ES2272279T3 (cg-RX-API-DMAC7.html)
FR (1) FR08C0013I2 (cg-RX-API-DMAC7.html)
HU (2) HU229866B1 (cg-RX-API-DMAC7.html)
IL (2) IL146434A0 (cg-RX-API-DMAC7.html)
LU (1) LU91418I2 (cg-RX-API-DMAC7.html)
MX (1) MXPA01011562A (cg-RX-API-DMAC7.html)
MY (1) MY164077A (cg-RX-API-DMAC7.html)
NL (1) NL300337I2 (cg-RX-API-DMAC7.html)
NO (2) NO324564B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ515423A (cg-RX-API-DMAC7.html)
PL (1) PL198185B1 (cg-RX-API-DMAC7.html)
PT (3) PT1176964E (cg-RX-API-DMAC7.html)
SI (3) SI1716853T1 (cg-RX-API-DMAC7.html)
SK (1) SK287580B6 (cg-RX-API-DMAC7.html)
TR (1) TR200103819T2 (cg-RX-API-DMAC7.html)
UA (1) UA74782C2 (cg-RX-API-DMAC7.html)
WO (1) WO2000069441A1 (cg-RX-API-DMAC7.html)

Families Citing this family (24)

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MY164077A (en) 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
MXPA02011319A (es) 2000-05-15 2003-06-06 Pharma Mar Sa Analogos antitumorales de ecteinascidina 743.
IL155781A0 (en) * 2000-11-06 2003-12-23 Pharma Mar Sa Effective antitumor treatments
GB0117402D0 (en) * 2001-07-17 2001-09-05 Pharma Mar Sa New antitumoral derivatives of et-743
US20050004018A1 (en) * 2001-10-19 2005-01-06 Jose Jimeno Use of antitumoral compound in cancer therapy
GB0202544D0 (en) 2002-02-04 2002-03-20 Pharma Mar Sa The synthesis of naturally occuring ecteinascidins and related compounds
GB0312407D0 (en) * 2003-05-29 2003-07-02 Pharma Mar Sau Treatment
GB0324201D0 (en) * 2003-10-15 2003-11-19 Pharma Mar Sau Improved antitumoral combinations
US7622458B2 (en) * 2003-11-13 2009-11-24 Pharma Mar, S.A.U. Combination of ET-743 and a 5-fluorouracil pro-drug for cancer treatment
AU2004291037A1 (en) * 2003-11-14 2005-06-02 Pharma Mar, S.A. Combination therapy comprising the use of ET-743 and paclitaxel for treating cancer
GB0326486D0 (en) * 2003-11-14 2003-12-17 Pharma Mar Sau Combination treatment
NZ552607A (en) * 2004-07-09 2009-07-31 Pharma Mar Sa Prognostic molecular markers
DE602005014380D1 (de) * 2004-10-26 2009-06-18 Ortho Biotech Products L P Pegyliertes liposomales doxorubicin in kombination mit ecteinescidin 743
DE602005001833T2 (de) * 2004-10-29 2008-04-17 Pharma Mar S.A., Sociedad Unipersonal Zusammensetzungen enthaltend Ecteinascidin und einen Disaccharide
GB0522082D0 (en) * 2005-10-31 2005-12-07 Pharma Mar Sa Formulations
EP2023931A2 (en) * 2006-05-12 2009-02-18 Pharma Mar S.A. Anticancer treatments with a combination of docetaxel and ecteinascidin
US20100267732A1 (en) * 2007-10-19 2010-10-21 Pharma Mar, S.A. Prognostic Molecular Markers for ET-743 Treatment
EP3412293A4 (en) * 2016-02-04 2019-10-16 Jiangsu Hengrui Medicine Co., Ltd. INJECTABLE PHARMACEUTICAL COMPOSITION WITH TRABECTEDIN FOR EXTERNAL GASTROINTESTINAL USE AND METHOD FOR THE PRODUCTION THEREOF
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
WO2020239478A1 (en) 2019-05-28 2020-12-03 Pharma Mar, S.A. Trabectedin for treating sarcomas based on genomic markers
CN112574234B (zh) * 2019-09-27 2022-05-24 江苏恒瑞医药股份有限公司 一种海鞘素衍生物的制备方法
KR20230002462A (ko) 2020-04-15 2023-01-05 에버 발린젝트 게엠베하 트라벡테딘 및 아미노산을 포함하는 조성물
EP3960177A1 (en) * 2020-08-26 2022-03-02 Anturec Pharmaceuticals GmbH Composition comprising ttf-ngr for use in treating soft-tissue sarcoma
US12303506B2 (en) 2022-01-20 2025-05-20 Extrovis Ag Trabectedin composition

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US5089273A (en) * 1986-06-09 1992-02-18 Board Of Trustees Of The University Of Illinois Ecteinascidins 729, 743, 745, 759A, 759B and 770
US5256663A (en) 1986-06-09 1993-10-26 The Board Of Trustees Of The University Of Illinois Compositions comprising ecteinascidins and a method of treating herpes simplex virus infections therewith
US5149804A (en) * 1990-11-30 1992-09-22 The Board Of Trustees Of The University Of Illinois Ecteinascidins 736 and 722
DE3635711A1 (de) 1986-10-21 1988-04-28 Knoll Ag 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung
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PT1586322E (pt) * 1996-11-05 2008-10-27 Childrens Medical Center Composições que compreendem talidomida e dexametasona para o tratamento de cancro
IL123740A0 (en) * 1997-03-28 1998-10-30 Pfizer NK-1 receptor antagonists for the treatment of delayed emesis
US5985876A (en) 1997-04-15 1999-11-16 Univ Illinois Nucleophile substituted ecteinascidins and N-oxide ecteinascidins
DE19720312A1 (de) * 1997-05-15 1998-11-19 Hoechst Ag Zubereitung mit erhöhter in vivo Verträglichkeit
GB9801231D0 (en) * 1997-06-05 1998-03-18 Merck & Co Inc A method of treating cancer
PL196809B1 (pl) * 1998-04-06 2008-02-29 Univ Illinois Półsyntetyczne ekteinascydyny, kompozycje farmaceutyczne oraz zastosowanie półsyntetycznych ekteinascydyn
HUP0101960A3 (en) * 1998-05-11 2003-03-28 Pharma Mar Sa Metabolites of ecteinascidin 743, their use and pharmaceutical compositions containing them
US6124292A (en) 1998-09-30 2000-09-26 President And Fellows Of Harvard College Synthetic analogs of ecteinascidin-743
MY164077A (en) 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
AR035842A1 (es) 1999-05-14 2004-07-21 Pharma Mar Sa Metodo de hemisintesis para la formacion de compuestos intermediarios y derivados y de estructuras relacionadas con la ecteinascidina y de tetrahidroisoquinolinfenoles y compuestos intermediarios de aplicacion en dicho metodo
DE60111845T2 (de) 2000-04-12 2006-04-27 Pharma Mar, S.A., Tres Cantos Ecteinaschidin derivate mit antikrebs wirkung
US7247892B2 (en) 2000-04-24 2007-07-24 Taylor Geoff W Imaging array utilizing thyristor-based pixel elements
MXPA02011319A (es) 2000-05-15 2003-06-06 Pharma Mar Sa Analogos antitumorales de ecteinascidina 743.
US7420051B2 (en) 2000-05-15 2008-09-02 Pharma Mar, S.A. Synthetic process for the manufacture of an ecteinaschidin compound
WO2002014554A2 (en) 2000-08-11 2002-02-21 City Of Hope The anti-neoplastic agent et-743 inhibits trans activation by sxr
IL155781A0 (en) 2000-11-06 2003-12-23 Pharma Mar Sa Effective antitumor treatments
EP1360337A1 (en) 2001-02-09 2003-11-12 The Regents Of The University Of California Ecteinascidin family compounds: compositions and methods
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GB0121285D0 (en) 2001-09-03 2001-10-24 Cancer Res Ventures Ltd Anti-cancer combinations
US20050004018A1 (en) 2001-10-19 2005-01-06 Jose Jimeno Use of antitumoral compound in cancer therapy
US20040019027A1 (en) 2002-04-12 2004-01-29 Barry Forman Method of treating cerebrotendinous xanthomatosis
GB0312407D0 (en) 2003-05-29 2003-07-02 Pharma Mar Sau Treatment
GB0324201D0 (en) 2003-10-15 2003-11-19 Pharma Mar Sau Improved antitumoral combinations
US7622458B2 (en) 2003-11-13 2009-11-24 Pharma Mar, S.A.U. Combination of ET-743 and a 5-fluorouracil pro-drug for cancer treatment
GB0326486D0 (en) 2003-11-14 2003-12-17 Pharma Mar Sau Combination treatment
AU2004291037A1 (en) 2003-11-14 2005-06-02 Pharma Mar, S.A. Combination therapy comprising the use of ET-743 and paclitaxel for treating cancer
NZ552607A (en) 2004-07-09 2009-07-31 Pharma Mar Sa Prognostic molecular markers
CN101068596A (zh) 2004-09-29 2007-11-07 法马马私人股份有限公司 艾可特耐思地作抗炎药
DE602005014380D1 (de) 2004-10-26 2009-06-18 Ortho Biotech Products L P Pegyliertes liposomales doxorubicin in kombination mit ecteinescidin 743
DE602005001833T2 (de) 2004-10-29 2008-04-17 Pharma Mar S.A., Sociedad Unipersonal Zusammensetzungen enthaltend Ecteinascidin und einen Disaccharide
ES2361566T3 (es) 2005-11-25 2011-06-20 Pharma Mar S.A., Sociedad Unipersonal Uso de inhibidores de parp-1.
EP2023931A2 (en) 2006-05-12 2009-02-18 Pharma Mar S.A. Anticancer treatments with a combination of docetaxel and ecteinascidin

Also Published As

Publication number Publication date
BR0010531A (pt) 2002-06-04
DE60036826D1 (de) 2007-11-29
NO20015516D0 (no) 2001-11-12
DK1176964T3 (da) 2007-01-15
IL146434A0 (en) 2002-07-25
AU777417B2 (en) 2004-10-14
SI1702618T1 (sl) 2008-02-29
CZ20014081A3 (cs) 2002-11-13
MY164077A (en) 2017-11-30
LU91418I2 (fr) 2008-05-13
CN1679631A (zh) 2005-10-12
HUP0201187A3 (en) 2002-11-28
PL352931A1 (en) 2003-09-22
HU229866B1 (en) 2014-10-28
DE60036826T2 (de) 2008-08-28
EP1716853B9 (en) 2011-09-28
FR08C0013I1 (cg-RX-API-DMAC7.html) 2008-05-30
SI1716853T1 (sl) 2011-10-28
CY2008007I2 (el) 2009-11-04
DK1702618T3 (da) 2008-02-25
CY2008007I1 (el) 2009-11-04
NL300337I1 (nl) 2008-05-01
NO20015516L (no) 2002-01-11
ES2294756T3 (es) 2008-04-01
NZ515423A (en) 2004-04-30
EP1716853A2 (en) 2006-11-02
EP1702618A3 (en) 2006-12-27
FR08C0013I2 (fr) 2009-10-30
HUS1500001I1 (hu) 2016-08-29
DE60045720D1 (de) 2011-04-21
AU2005200180B2 (en) 2007-12-13
TR200103819T2 (tr) 2002-04-22
AU4597500A (en) 2000-12-05
EP1176964B8 (en) 2007-10-10
BG106171A (en) 2002-06-28
PL198185B1 (pl) 2008-06-30
CY1105818T1 (el) 2011-02-02
DE60030554T2 (de) 2007-09-13
KR20020019914A (ko) 2002-03-13
HUP0201187A2 (en) 2002-09-28
CN100477993C (zh) 2009-04-15
EP1176964B1 (en) 2006-09-06
AR028476A1 (es) 2003-05-14
ATE500830T1 (de) 2011-03-15
NO2008005I2 (cg-RX-API-DMAC7.html) 2010-09-27
EP1716853B1 (en) 2011-03-09
DE122008000013I1 (de) 2008-08-07
CN1360503A (zh) 2002-07-24
IL146434A (en) 2008-03-20
UA74782C2 (uk) 2006-02-15
NO324564B1 (no) 2007-11-19
US8119638B2 (en) 2012-02-21
CY1112753T1 (el) 2016-02-10
EP1702618A2 (en) 2006-09-20
NO2008005I1 (no) 2008-06-09
SK287580B6 (sk) 2011-03-04
SI1176964T1 (sl) 2007-02-28
SK16442001A3 (sk) 2002-03-05
WO2000069441A1 (en) 2000-11-23
LU91418I9 (cg-RX-API-DMAC7.html) 2019-01-02
EP1176964A1 (en) 2002-02-06
CZ301482B6 (cs) 2010-03-17
CA2373794A1 (en) 2000-11-23
JP5777562B2 (ja) 2015-09-09
DK1716853T3 (da) 2011-06-27
AU2005200180B9 (en) 2008-05-29
ES2272279T3 (es) 2007-05-01
NL300337I2 (nl) 2008-09-01
CA2373794C (en) 2005-10-11
EP1702618B1 (en) 2007-10-17
ATE338552T1 (de) 2006-09-15
PT1716853E (pt) 2011-05-12
JP2002544231A (ja) 2002-12-24
BG65680B1 (bg) 2009-06-30
PT1176964E (pt) 2007-01-31
DE60030554T8 (de) 2008-01-10
CY1107143T1 (el) 2010-07-28
EP1716853A3 (en) 2006-11-15
ATE375795T1 (de) 2007-11-15
US20070275942A1 (en) 2007-11-29
JP2012149095A (ja) 2012-08-09
PT1702618E (pt) 2008-01-11
AU2005200180A1 (en) 2005-02-10
DE60030554D1 (de) 2006-10-19

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