| US6407213B1
              (en) | 1991-06-14 | 2002-06-18 | Genentech, Inc. | Method for making humanized antibodies | 
        
          | US6800738B1
              (en) | 1991-06-14 | 2004-10-05 | Genentech, Inc. | Method for making humanized antibodies | 
        
          | US6417168B1
              (en) | 1998-03-04 | 2002-07-09 | The Trustees Of The University Of Pennsylvania | Compositions and methods of treating tumors | 
        
          | EP1745799B1
              (en) | 1998-03-04 | 2015-09-02 | The Trustees of The University of Pennsylvania | Compositions and methods of treating tumors | 
        
          | US6706721B1
              (en) | 1998-04-29 | 2004-03-16 | Osi Pharmaceuticals, Inc. | N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate | 
        
          | AU780454B2
              (en) | 1999-06-03 | 2005-03-24 | Jessie L.S. Au | Methods and compositions for modulating cell proliferation and cell death | 
        
          | GB9925958D0
              (en)
            
            * | 1999-11-02 | 1999-12-29 | Bundred Nigel J | Therapeutic use | 
        
          | US7087613B2
              (en) | 1999-11-11 | 2006-08-08 | Osi Pharmaceuticals, Inc. | Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride | 
        
          | UA74803C2
              (uk) | 1999-11-11 | 2006-02-15 | Осі Фармасьютікалз, Інк. | Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування | 
        
          | EP1311291A4
              (en)
            
            * | 2000-08-09 | 2007-07-25 | Imclone Systems Inc | TREATMENT OF HYPERPROLIFERATIVE DISEASES USING EPIDERMAL GROWTH FACTOR RECEPTOR ANTAGONISTS | 
        
          | CU22979A1
              (es)
            
            * | 2000-12-08 | 2004-09-09 | Centro Inmunologia Molecular | Combinación inmunoterapéutica para el tratamiento de tumores que sobre-expresan receptores con actividad quinasa en residuos de tirosina | 
        
          | AU2002239486A1
              (en)
            
            * | 2000-12-08 | 2002-06-18 | Uab Research Foundation | Combination radiation therapy and chemotherapy in conjuction with administration of growth factor receptor antibody | 
        
          | US7081454B2
              (en) | 2001-03-28 | 2006-07-25 | Bristol-Myers Squibb Co. | Tyrosine kinase inhibitors | 
        
          | WO2003075840A2
              (en) | 2002-03-04 | 2003-09-18 | Imclone Systems Incorporated | Human antibodies specific to kdr and uses thereof | 
        
          | DE60318561T2
              (de)
            
            * | 2002-04-02 | 2009-01-08 | Nerviano Medical Sciences S.R.L., Nerviano | Kombinierte tumortherapie auf der basis von distamycin-acryloyl derivaten und radiotherapie | 
        
          | NZ554740A
              (en) | 2002-05-24 | 2009-01-31 | Schering Corp | Neutralizing human anti-IGFR antibody | 
        
          | WO2005016970A2
              (en) | 2003-05-01 | 2005-02-24 | Imclone Systems Incorporated | Fully human antibodies directed against the human insulin-like growth factor-1 receptor | 
        
          | EP1638600A4
              (en) | 2003-06-09 | 2008-06-11 | Samuel Waksal | PROCESS FOR INHIBITING RECEPTOR TYROSINE KINASES WITH AN EXTRACELLULAR ANTAGONIST AND AN INTRA CELLULAR ANTAGONIST | 
        
          | US7312215B2
              (en) | 2003-07-29 | 2007-12-25 | Bristol-Myers Squibb Company | Benzimidazole C-2 heterocycles as kinase inhibitors | 
        
          | RS20060099A
              (en) | 2003-08-13 | 2008-08-07 | Pfizer Products Inc., | Modified human igf-1r antibodies | 
        
          | CA2545755A1
              (en) | 2003-11-12 | 2005-05-26 | Schering Corporation | Plasmid system for multigene expression | 
        
          | TW200526684A
              (en) | 2003-11-21 | 2005-08-16 | Schering Corp | Anti-IGFR1 antibody therapeutic combinations | 
        
          | PT1735348E
              (pt)
            
            * | 2004-03-19 | 2012-07-24 | Imclone Llc | Anticorpo anti-receptor do factor de crescimento humano | 
        
          | EP1758601A1
              (en) | 2004-06-03 | 2007-03-07 | F.Hoffmann-La Roche Ag | Treatment with cisplatin and an egfr-inhibitor | 
        
          | RU2342159C2
              (ru) | 2004-07-16 | 2008-12-27 | Пфайзер Продактс Инк. | Комбинированная терапия негематологических злокачественных опухолей с использованием анти-igf-1r-антитела | 
        
          | MX2007006640A
              (es) | 2004-12-03 | 2007-06-19 | Schering Corp | Biomarcadores para la preseleccion de pacientes para la terapia con anti-receptor 1 del factor de crecimiento similar a la insulina. | 
        
          | MY146381A
              (en) | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies | 
        
          | PL2100618T3
              (pl) | 2005-06-17 | 2014-07-31 | Imclone Llc | Przeciwciało anty-PDGFR alfa do zastosowania w leczeniu przerzutowego raka kości | 
        
          | WO2007035744A1
              (en) | 2005-09-20 | 2007-03-29 | Osi Pharmaceuticals, Inc. | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors | 
        
          | CA2625440C
              (en) | 2005-10-11 | 2023-06-13 | Micromet Ag | Compositions comprising cross-species-specific antibodies and uses thereof | 
        
          | TW200812615A
              (en) | 2006-03-22 | 2008-03-16 | Hoffmann La Roche | Tumor therapy with an antibody for vascular endothelial growth factor and an antibody for human epithelial growth factor receptor type 2 | 
        
          | CL2007002404A1
              (es) | 2006-08-21 | 2008-04-18 | Hoffmann La Roche | Uso de un anticuerpo anti-vegf (factor de crecimiento endotelial vascular) para el tratamiento de un paciente que padece una recaida de cancer her2 positivo durante o despues del tratamiento con un anticuerpo anti-her2. | 
        
          | HRP20131113T1
              (hr) | 2007-02-16 | 2014-01-17 | Merrimack Pharmaceuticals, Inc. | Protutijela protiv erbb3 i njihova uporaba | 
        
          | MX2009010611A
              (es)
            
            * | 2007-04-03 | 2010-03-26 | Micromet Ag | Enlazadores biespecificos, especificos para especies. | 
        
          | WO2009030368A1
              (en) | 2007-09-05 | 2009-03-12 | F. Hoffmann-La Roche Ag | Combination therapy with type i and type ii anti-cd20 antibodies | 
        
          | US20090098118A1
              (en) | 2007-10-15 | 2009-04-16 | Thomas Friess | Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent | 
        
          | AR071891A1
              (es) | 2008-05-30 | 2010-07-21 | Imclone Llc | Anticuerpos humanos anti-flt3 (receptor tirosina cinasa 3 tipo fms humano) | 
        
          | AU2009281721A1
              (en) | 2008-08-15 | 2010-02-18 | Merrimack Pharmaceuticals, Inc. | Methods and systems for predicting response of cells to a therapeutic agent | 
        
          | JP2012518657A
              (ja) | 2009-02-25 | 2012-08-16 | オーエスアイ・ファーマシューティカルズ,エルエルシー | 併用抗癌治療 | 
        
          | WO2010099137A2
              (en) | 2009-02-26 | 2010-09-02 | Osi Pharmaceuticals, Inc. | In situ methods for monitoring the emt status of tumor cells in vivo | 
        
          | WO2010107968A1
              (en) | 2009-03-18 | 2010-09-23 | Osi Pharmaceuticals, Inc. | Combination cancer therapy comprising administration of an egfr inhibitor and an igf-1r inhibitor | 
        
          | KR20150036824A
              (ko) | 2009-03-20 | 2015-04-07 | 제넨테크, 인크. | 이중특이적 항-her 항체 | 
        
          | US20100247484A1
              (en) | 2009-03-31 | 2010-09-30 | Heinrich Barchet | Combination therapy of an afucosylated antibody and one or more of the cytokines gm csf, m csf and/or il3 | 
        
          | EP2236139A1
              (en) | 2009-03-31 | 2010-10-06 | F. Hoffmann-La Roche AG | Combination therapy of erlotinib with an anti-IGF-1R antibody, which does not inhibit binding of insulin to the insulin receptor | 
        
          | CN102470172B
              (zh) | 2009-08-14 | 2014-09-24 | 罗切格利卡特公司 | 无岩藻糖基化cd20抗体与氟达拉滨和/或米托蒽醌的联合疗法 | 
        
          | TWI409079B
              (zh) | 2009-08-14 | 2013-09-21 | Roche Glycart Ag | 非典型岩藻醣化cd20抗體與苯達莫斯汀(bendamustine)之組合療法 | 
        
          | AR078161A1
              (es) | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. | 
        
          | US20110275644A1
              (en) | 2010-03-03 | 2011-11-10 | Buck Elizabeth A | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors | 
        
          | CA2783665A1
              (en) | 2010-03-03 | 2011-09-09 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors | 
        
          | ES2535503T3
              (es) | 2010-03-11 | 2015-05-12 | Merrimack Pharmaceuticals, Inc. | Uso de inhibidores de ErbB3 en el tratamiento del cáncer de mama triple negativo | 
        
          | MX342590B
              (es) | 2010-04-27 | 2016-10-05 | Roche Glycart Ag | Terapia de combinacion de un anticuerpo cd20 afucosilado con un inhibidor mtor. | 
        
          | AR082693A1
              (es) | 2010-08-17 | 2012-12-26 | Roche Glycart Ag | Terapia de combinacion de un anticuerpo anti-cd20 afucosilado con un anticuerpo anti-vegf | 
        
          | TW201302793A
              (zh) | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 | 
        
          | RU2013131444A
              (ru) | 2010-12-16 | 2015-01-27 | Рош Гликарт Аг | Сочетанная терапия афукозилированным антителом к cd20 и ингибитором mdm2 | 
        
          | JP2014510265A
              (ja) | 2011-02-02 | 2014-04-24 | アムジェン  インコーポレイテッド | Igf−1rの阻害に関する方法および組成物 | 
        
          | WO2012116040A1
              (en) | 2011-02-22 | 2012-08-30 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma | 
        
          | WO2012129145A1
              (en) | 2011-03-18 | 2012-09-27 | OSI Pharmaceuticals, LLC | Nscle combination therapy | 
        
          | SG194111A1
              (en) | 2011-04-07 | 2013-11-29 | Amgen Inc | Novel egfr binding proteins | 
        
          | EP2702173A1
              (en) | 2011-04-25 | 2014-03-05 | OSI Pharmaceuticals, LLC | Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment | 
        
          | CA2852127C
              (en) | 2011-11-11 | 2020-10-27 | Duke University | Combination drug therapy for the treatment of solid tumors | 
        
          | US20130302274A1
              (en) | 2011-11-25 | 2013-11-14 | Roche Glycart Ag | Combination therapy | 
        
          | CN104136464A
              (zh)
            
            * | 2012-02-23 | 2014-11-05 | U3制药有限公司 | 用于调节放射敏感性的her3抑制剂 | 
        
          | AR090263A1
              (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma | 
        
          | WO2013152252A1
              (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy | 
        
          | MX2015002947A
              (es) | 2012-09-07 | 2015-09-23 | Genentech Inc | Terapia de combinacion de un anticuerpo ant-cd20 tipo ii con un inhibidor blc-2 selectivo. | 
        
          | AR094403A1
              (es) | 2013-01-11 | 2015-07-29 | Hoffmann La Roche | Terapia de combinación de anticuerpos anti-her3 | 
        
          | WO2015100459A2
              (en) | 2013-12-27 | 2015-07-02 | Merrimack Pharmaceuticals, Inc. | Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies | 
        
          | CA2943329A1
              (en) | 2014-03-24 | 2015-10-01 | Genentech, Inc. | Cancer treatment with c-met antagonists and correlation of the latter with hgf expression | 
        
          | US10184006B2
              (en) | 2015-06-04 | 2019-01-22 | Merrimack Pharmaceuticals, Inc. | Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors | 
        
          | CN113607945B
              (zh) | 2015-07-07 | 2025-01-28 | 豪夫迈·罗氏有限公司 | 抗HER2抗体-药物缀合物和Bcl-2抑制剂的组合疗法 | 
        
          | MX2018006781A
              (es) | 2015-12-03 | 2018-11-09 | Agios Pharmaceuticals Inc | Inhibidores de mat2a para el tratamiento del cancer que no expresen mtap. | 
        
          | WO2017125429A1
              (en) | 2016-01-18 | 2017-07-27 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | The use of a temporary inhibitor of p53 for preventing or reducing cancer relapse | 
        
          | CN116333130A
              (zh) | 2016-05-24 | 2023-06-27 | 英斯梅德股份有限公司 | 抗体及其制备方法 | 
        
          | WO2019020610A1
              (en) | 2017-07-26 | 2019-01-31 | F. Hoffmann-La Roche Ag | POLYTHERAPY USING BET INHIBITOR AND BCL-2 INHIBITOR | 
        
          | CN110869391A
              (zh) | 2017-07-26 | 2020-03-06 | 豪夫迈·罗氏有限公司 | 用BET抑制剂,Bcl-2抑制剂和抗CD20抗体的组合疗法 | 
        
          | WO2019062755A1
              (en)
            
            * | 2017-09-29 | 2019-04-04 | Wuxi Biologics (Shanghai) Co., Ltd. | BISPECIFIC ANTIBODIES DIRECTED AGAINST EGFR AND PD-1 | 
        
          | JP2021521219A
              (ja) | 2018-04-18 | 2021-08-26 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | Bet阻害剤およびプロテアソーム阻害剤を用いる併用療法 | 
        
          | WO2020234445A1
              (en) | 2019-05-23 | 2020-11-26 | F. Hoffmann-La Roche Ag | Combination therapy with a bet inhibitor and a bcl-2 inhibitor | 
        
          | WO2021155006A1
              (en) | 2020-01-31 | 2021-08-05 | Les Laboratoires Servier Sas | Inhibitors of cyclin-dependent kinases and uses thereof |