ATE339957T1 - Verwendung von egfr tyrosine kinase hemmern zur behandlung von brustkrebs - Google Patents
Verwendung von egfr tyrosine kinase hemmern zur behandlung von brustkrebsInfo
- Publication number
- ATE339957T1 ATE339957T1 AT00973002T AT00973002T ATE339957T1 AT E339957 T1 ATE339957 T1 AT E339957T1 AT 00973002 T AT00973002 T AT 00973002T AT 00973002 T AT00973002 T AT 00973002T AT E339957 T1 ATE339957 T1 AT E339957T1
- Authority
- AT
- Austria
- Prior art keywords
- breast cancer
- tyrosine kinase
- egfr tyrosine
- kinase inhibitors
- treat breast
- Prior art date
Links
- 229940121647 egfr inhibitor Drugs 0.000 title abstract 2
- 206010006187 Breast cancer Diseases 0.000 title 1
- 208000026310 Breast neoplasm Diseases 0.000 title 1
- 230000002113 chemopreventative effect Effects 0.000 abstract 1
- 208000030776 invasive breast carcinoma Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9925958.2A GB9925958D0 (en) | 1999-11-02 | 1999-11-02 | Therapeutic use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE339957T1 true ATE339957T1 (de) | 2006-10-15 |
Family
ID=10863835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00973002T ATE339957T1 (de) | 1999-11-02 | 2000-11-01 | Verwendung von egfr tyrosine kinase hemmern zur behandlung von brustkrebs |
Country Status (21)
Country | Link |
---|---|
US (1) | US7553815B1 (de) |
EP (1) | EP1272188B1 (de) |
JP (1) | JP2003513035A (de) |
KR (1) | KR100785359B1 (de) |
CN (1) | CN1197577C (de) |
AT (1) | ATE339957T1 (de) |
AU (1) | AU779190B2 (de) |
BR (1) | BR0015194A (de) |
CA (1) | CA2389411C (de) |
CY (1) | CY1106285T1 (de) |
DE (1) | DE60030889T2 (de) |
DK (1) | DK1272188T3 (de) |
ES (1) | ES2275556T3 (de) |
GB (1) | GB9925958D0 (de) |
IL (1) | IL149176A0 (de) |
MX (1) | MXPA02004272A (de) |
NO (1) | NO323206B1 (de) |
NZ (1) | NZ518696A (de) |
PT (1) | PT1272188E (de) |
WO (1) | WO2001032155A2 (de) |
ZA (1) | ZA200203431B (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1282443T3 (da) | 2000-05-19 | 2010-01-04 | Genentech Inc | Gendetektionsassay til at forbedre sandsynligheden for et effektivt respons på en ErbB-antagonist cancerterapi |
AU2002350105A1 (en) | 2001-06-21 | 2003-01-08 | Ariad Pharmaceuticals, Inc. | Novel quinazolines and uses thereof |
US6872715B2 (en) * | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
WO2003037897A2 (en) * | 2001-10-29 | 2003-05-08 | Novartis Ag | Use of 7h-pyrrolo[2,3-d]pyrimidine derivatives in the treatment of solid tumor diseases |
SI1450799T1 (sl) * | 2001-12-03 | 2007-02-28 | Bayer Pharmaceuticals Corp | Aril secninske spojine v kombinaciji z drugimi citostaticnimi ali citotoksicnimi sredstvi za zdravljenje cloveskih rakov |
US7078409B2 (en) | 2002-03-28 | 2006-07-18 | Beta Pharma, Inc. | Fused quinazoline derivatives useful as tyrosine kinase inhibitors |
ATE547708T1 (de) | 2002-06-05 | 2012-03-15 | Cedars Sinai Medical Center | Verfahren zur handhabung der kinasehemmertherapie |
WO2005017493A2 (en) * | 2003-08-15 | 2005-02-24 | Smithkline Beecham Corporation | Biomarkers in cancer |
RU2370494C2 (ru) | 2003-09-19 | 2009-10-20 | Астразенека Аб | Производные хиназолина |
WO2005039588A2 (en) * | 2003-10-22 | 2005-05-06 | Novartis Ag | Methods for determining the risk of developing liver and lung toxicity |
US7701341B2 (en) * | 2004-09-01 | 2010-04-20 | Microsoft Corporation | Device service provider interface |
CN102580084B (zh) | 2005-01-21 | 2016-11-23 | 健泰科生物技术公司 | Her抗体的固定剂量给药 |
CN103251946A (zh) | 2005-02-23 | 2013-08-21 | 健泰科生物技术公司 | 使用her二聚化抑制剂在癌症患者中延长病情进展前时间或存活 |
CN101003514A (zh) | 2006-01-20 | 2007-07-25 | 上海艾力斯医药科技有限公司 | 喹唑啉衍生物、其制备方法及用途 |
JP5133071B2 (ja) | 2006-02-09 | 2013-01-30 | 第一三共株式会社 | 抗癌医薬組成物 |
CN1899616A (zh) * | 2006-07-20 | 2007-01-24 | 中国人民解放军军事医学科学院生物工程研究所 | 非受体酪氨酸激酶c-Abl特异性抑制剂的新用途 |
SI2132573T1 (sl) | 2007-03-02 | 2014-07-31 | Genentech, Inc. | Napovedovanje odziva na inhibitor dimerizacije HER na osnovi nizke ekspresije HER3 |
US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
ES2583377T3 (es) | 2007-06-08 | 2016-09-20 | Genentech, Inc. | Marcadores de expresión génica de la resistencia tumoral al tratamiento con inhibidor de HER2 |
BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
JP5767122B2 (ja) | 2009-03-11 | 2015-08-19 | アルデア バイオサイエンシズ,インコーポレイティド | 特定の癌の治療のためのrdea119/bay869766を含む組み合わせ医薬 |
SG174378A1 (en) | 2009-03-20 | 2011-10-28 | Genentech Inc | Bispecific anti-her antibodies |
CA2761280A1 (en) | 2009-05-29 | 2010-12-02 | F. Hoffmann-La Roche Ag | Modulators for her2 signaling in her2 expressing patients with gastric cancer |
EP2536748B1 (de) | 2010-02-18 | 2014-08-20 | Genentech, Inc. | Neuregulin-antagonisten und ihre verwendung zur behandlung von krebs |
WO2011146568A1 (en) | 2010-05-19 | 2011-11-24 | Genentech, Inc. | Predicting response to a her inhibitor |
WO2012069466A1 (en) | 2010-11-24 | 2012-05-31 | Novartis Ag | Multispecific molecules |
EP2655413B1 (de) | 2010-12-23 | 2019-01-16 | F.Hoffmann-La Roche Ag | Polypeptid-polynukleotid-komplex und verwendung bei der gezielten effektorrest-bereitstellung |
CA2842375A1 (en) | 2011-08-17 | 2013-02-21 | Erica Jackson | Neuregulin antibodies and uses thereof |
US9327023B2 (en) | 2011-10-25 | 2016-05-03 | The Regents Of The University Of Michigan | HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells |
RU2014126098A (ru) | 2011-11-30 | 2016-01-27 | Дженентек, Инк. | МУТАЦИИ ErbB3 ПРИ РАКЕ |
WO2013083810A1 (en) | 2011-12-09 | 2013-06-13 | F. Hoffmann-La Roche Ag | Identification of non-responders to her2 inhibitors |
WO2013148315A1 (en) | 2012-03-27 | 2013-10-03 | Genentech, Inc. | Diagnosis and treatments relating to her3 inhibitors |
CN104813168B (zh) | 2012-11-30 | 2017-10-20 | 霍夫曼-拉罗奇有限公司 | 需要pd‑l1抑制剂综合疗法的患者的鉴定 |
US20190151346A1 (en) | 2016-05-10 | 2019-05-23 | INSERM (Institute National de la Santé et de la Recherche Médicale) | Combinations therapies for the treatment of cancer |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU661533B2 (en) * | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
US5795910A (en) * | 1994-10-28 | 1998-08-18 | Cor Therapeutics, Inc. | Method and compositions for inhibiting protein kinases |
DK0817775T3 (da) * | 1995-03-30 | 2001-11-19 | Pfizer | Quinazolinderivater |
GB9508538D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
GB9508565D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quiazoline derivative |
ES2203642T3 (es) * | 1995-06-07 | 2004-04-16 | Pfizer Inc. | Derivados de pirimidina heterociclicos con anillos condensados. |
JP4146514B2 (ja) * | 1995-07-06 | 2008-09-10 | ノバルティス アクチエンゲゼルシャフト | ピロロピリミジン類およびその製造方法 |
JP2002515511A (ja) * | 1998-05-15 | 2002-05-28 | イムクローン システムズ インコーポレイティド | 放射線及び成長因子レセプター・チロシン・キナーゼのインヒビターを使用するヒト腫瘍の治療 |
CN101512597B (zh) | 2006-08-28 | 2013-02-06 | Tp视觉控股有限公司 | 图像增强方法和设备 |
-
1999
- 1999-11-02 GB GBGB9925958.2A patent/GB9925958D0/en not_active Ceased
-
2000
- 2000-11-01 US US10/111,390 patent/US7553815B1/en not_active Expired - Fee Related
- 2000-11-01 DE DE60030889T patent/DE60030889T2/de not_active Expired - Lifetime
- 2000-11-01 WO PCT/GB2000/004190 patent/WO2001032155A2/en active IP Right Grant
- 2000-11-01 DK DK00973002T patent/DK1272188T3/da active
- 2000-11-01 JP JP2001534360A patent/JP2003513035A/ja active Pending
- 2000-11-01 PT PT00973002T patent/PT1272188E/pt unknown
- 2000-11-01 ES ES00973002T patent/ES2275556T3/es not_active Expired - Lifetime
- 2000-11-01 CN CNB00815290XA patent/CN1197577C/zh not_active Expired - Fee Related
- 2000-11-01 NZ NZ518696A patent/NZ518696A/xx not_active IP Right Cessation
- 2000-11-01 IL IL14917600A patent/IL149176A0/xx not_active IP Right Cessation
- 2000-11-01 BR BR0015194-7A patent/BR0015194A/pt not_active Application Discontinuation
- 2000-11-01 EP EP00973002A patent/EP1272188B1/de not_active Expired - Lifetime
- 2000-11-01 MX MXPA02004272A patent/MXPA02004272A/es active IP Right Grant
- 2000-11-01 KR KR1020027005551A patent/KR100785359B1/ko not_active IP Right Cessation
- 2000-11-01 AU AU11559/01A patent/AU779190B2/en not_active Ceased
- 2000-11-01 CA CA002389411A patent/CA2389411C/en not_active Expired - Fee Related
- 2000-11-01 AT AT00973002T patent/ATE339957T1/de not_active IP Right Cessation
-
2002
- 2002-04-30 ZA ZA200203431A patent/ZA200203431B/xx unknown
- 2002-04-30 NO NO20022065A patent/NO323206B1/no not_active IP Right Cessation
-
2006
- 2006-12-11 CY CY20061101772T patent/CY1106285T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2275556T3 (es) | 2007-06-16 |
NZ518696A (en) | 2004-12-24 |
AU779190B2 (en) | 2005-01-13 |
EP1272188A2 (de) | 2003-01-08 |
NO20022065D0 (no) | 2002-04-30 |
ZA200203431B (en) | 2003-02-26 |
US7553815B1 (en) | 2009-06-30 |
DE60030889T2 (de) | 2007-04-05 |
CY1106285T1 (el) | 2011-10-12 |
EP1272188B1 (de) | 2006-09-20 |
CA2389411A1 (en) | 2001-05-10 |
NO323206B1 (no) | 2007-01-22 |
BR0015194A (pt) | 2002-06-18 |
NO20022065L (no) | 2002-06-24 |
JP2003513035A (ja) | 2003-04-08 |
GB9925958D0 (en) | 1999-12-29 |
CN1197577C (zh) | 2005-04-20 |
KR100785359B1 (ko) | 2007-12-18 |
CA2389411C (en) | 2009-09-01 |
DK1272188T3 (da) | 2007-01-29 |
MXPA02004272A (es) | 2003-08-20 |
PT1272188E (pt) | 2007-01-31 |
WO2001032155A2 (en) | 2001-05-10 |
KR20020064306A (ko) | 2002-08-07 |
WO2001032155A3 (en) | 2002-05-10 |
IL149176A0 (en) | 2002-11-10 |
DE60030889D1 (de) | 2006-11-02 |
AU1155901A (en) | 2001-05-14 |
CN1387437A (zh) | 2002-12-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE339957T1 (de) | Verwendung von egfr tyrosine kinase hemmern zur behandlung von brustkrebs | |
ATE362363T1 (de) | Verwendung von tnf-alpha inhibitoren zur behandlung von nervenwurzelschäden | |
ATE323474T1 (de) | Farnesyl protein transferase inhibitoren zur behandlung von brustkrebs | |
MXPA00011248A (es) | Tratamientos de tumores humanos con radiacion e inhibidores de tirosina cinasas de recptor de factor de crecimiento. | |
ATE241358T1 (de) | Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen | |
DE60037394D1 (de) | VERWENDUNG VON p53 INHIBITOREN ZUR BEHANDLUNG VON NEBENERSCHEINUNGEN BEI DER KREBSTHERAPIE | |
AR023400A1 (es) | Metodos para inducir la muerte de celulas cancerosas y la regresion de tumores | |
EA200300906A1 (ru) | Новые спиротрициклические производные и их применение в качестве ингибиторов фосфодиэстеразы-7 | |
MY151032A (en) | Treatment of tnf? related disorders | |
DE60032795D1 (de) | Nordihydroguaiaretinsäurederivate zur behandlung von tumoren | |
ATE321548T1 (de) | Verwendung von statin zur behandlung von hauterkrankungen | |
TNSN04015A1 (en) | Combination therapy for the treatment of cancer | |
DE602004022285D1 (de) | Verfahren zur behandlung von erkrankungen mit hsp90-hemmenden mitteln in kombination mit antimitotika | |
ATE410155T1 (de) | Verwendung von cyclin-d1-hemmern zur brustkrebsbehandlung | |
CY1106289T1 (el) | Χρηση αναστολεων υποδοχεος προγεστepονης για τη θepαπευτικη αντιμετωπιση του καρκινου του μαστου που ειναι ανθεκτικος σε στepοειδη | |
HK1080733A1 (en) | Pharmaceutical composition for use for the treatment of malignancies comprising in combination a bisphosphonates, a cox-2 inhibitor and a taxol | |
MX2007006927A (es) | Combinacion de inhibidor de tirosina cinasa y her-2/neu para terapia de cancer. | |
DE69829202D1 (de) | Verwendung von mirtazapine zur herstellung eines medikaments zur behandlung von schlafapnoen | |
ATE350032T1 (de) | Verwendung der protein-kinase-c-epsilon- inhibitoren zur behandlung von schmerzen | |
DE60309887D1 (de) | Kombination von einem aromatasehemmer mit einem bisphosphonat | |
DE59902666D1 (de) | Edelfosin zur behandlung von hirntumoren | |
DE60220825D1 (de) | Verwendung von norepinephrinwiederaufnahmehemmern zur behandlung von ticks | |
ATE291434T1 (de) | Verwendung von angiotensin zur behandlung von krebsmetastasierung | |
DE60326348D1 (de) | Makrozyclen zur behandlung von krebserkrankungen | |
ATE486594T1 (de) | Methode zur behandlung von herzinsuffizienz |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1272188 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |