MX2007006927A - Combinacion de inhibidor de tirosina cinasa y her-2/neu para terapia de cancer. - Google Patents

Combinacion de inhibidor de tirosina cinasa y her-2/neu para terapia de cancer.

Info

Publication number
MX2007006927A
MX2007006927A MX2007006927A MX2007006927A MX2007006927A MX 2007006927 A MX2007006927 A MX 2007006927A MX 2007006927 A MX2007006927 A MX 2007006927A MX 2007006927 A MX2007006927 A MX 2007006927A MX 2007006927 A MX2007006927 A MX 2007006927A
Authority
MX
Mexico
Prior art keywords
neu
combination
tyrosine kinase
kinase inhibitor
cancer therapy
Prior art date
Application number
MX2007006927A
Other languages
English (en)
Inventor
Claudine Elvire Marie Bruck
Catherine Marie Ghislaine Gerard
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of MX2007006927A publication Critical patent/MX2007006927A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe un metodo para tratar el cancer que comprende la administracion de una 4-quinazolinamina y una vacuna que trata la molecula HER-2/neu, asi como una combinacion farmaceutica que comprende 4-quinazolinaminas y una vacuna que trata la molecula HER-2/neu.
MX2007006927A 2004-12-10 2005-12-08 Combinacion de inhibidor de tirosina cinasa y her-2/neu para terapia de cancer. MX2007006927A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0427131.8A GB0427131D0 (en) 2004-12-10 2004-12-10 Novel combination
PCT/EP2005/013409 WO2006061253A2 (en) 2004-12-10 2005-12-08 Combination of tyrosine kinase inhibitor and her-2/neu for cancer therapy

Publications (1)

Publication Number Publication Date
MX2007006927A true MX2007006927A (es) 2007-06-26

Family

ID=34073534

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007006927A MX2007006927A (es) 2004-12-10 2005-12-08 Combinacion de inhibidor de tirosina cinasa y her-2/neu para terapia de cancer.

Country Status (15)

Country Link
US (1) US20100028414A1 (es)
EP (1) EP1824509A2 (es)
JP (1) JP2008523017A (es)
KR (1) KR20070098857A (es)
CN (1) CN101115499A (es)
AU (1) AU2005313439A1 (es)
BR (1) BRPI0518619A2 (es)
CA (1) CA2589981A1 (es)
GB (1) GB0427131D0 (es)
IL (1) IL183448A0 (es)
MA (1) MA29133B1 (es)
MX (1) MX2007006927A (es)
NO (1) NO20072668L (es)
RU (1) RU2007120462A (es)
WO (1) WO2006061253A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7972602B2 (en) * 2006-08-11 2011-07-05 Dendreon Corporation Promiscuous HER-2/Neu CD4 T cell epitopes
WO2008088861A2 (en) * 2007-01-18 2008-07-24 University Of Southern California Gene polymorphisms predictive for dual tki therapy
US8623592B2 (en) * 2008-08-15 2014-01-07 Merrimack Pharmaceuticals, Inc. Methods and systems for predicting response of cells to a therapeutic agent
EP2328613A1 (en) * 2008-08-28 2011-06-08 GlaxoSmithKline Biologicals S.A. Vaccine
WO2012018260A1 (en) * 2010-08-05 2012-02-09 Universiteit Utrecht Holding B.V. Epidermal growth factor receptor targeted immune therapy
CN107531320B (zh) * 2015-03-19 2021-12-21 威罗门飞行公司 抗机械冲击印刷电路板(pcb)的安装系统
RU2603943C1 (ru) * 2016-02-01 2016-12-10 Индивидуальный предприниматель Михайлов Олег Ростиславович КРИСТАЛЛИЧЕСКАЯ γ-МОДИФИКАЦИЯ N-{3-ХЛОР-4-[(3-ФТОРБЕНЗИЛ)ОКСИ] ФЕНИЛ}-6-[5-({[2-(МЕТАНСУЛЬФОНИЛ)ЭТИЛ]АМИНО}МЕТИЛ)-2-ФУРИЛ]-4-ХИНАЗОЛИНАМИНА БИС (4-МЕТИЛБЕНЗОЛСУЛЬФОНАТА) МОНОГИДРАТА, СПОСОБ ЕЁ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕЁ ОСНОВЕ
US20210121518A1 (en) * 2018-02-15 2021-04-29 Board of Supervisors for the University of Louisiana System Her2-targeted peptidomimetics grafted onto multicyclic peptide scaffolds and methods and uses

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4436727A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4866034A (en) * 1982-05-26 1989-09-12 Ribi Immunochem Research Inc. Refined detoxified endotoxin
US4877611A (en) * 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
US4912094B1 (en) * 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
US5856462A (en) * 1996-09-10 1999-01-05 Hybridon Incorporated Oligonucleotides having modified CpG dinucleosides
GB9717953D0 (en) * 1997-08-22 1997-10-29 Smithkline Beecham Biolog Vaccine
GB9800569D0 (en) * 1998-01-12 1998-03-11 Glaxo Group Ltd Heterocyclic compounds
IL144371A0 (en) * 1999-01-29 2002-05-23 Corixa Corp Her-2/neu fusion proteins
TW200914443A (en) * 2000-06-30 2009-04-01 Glaxo Group Ltd Process for preparing substituted quinazolinyl furanaldehyde
ES2236481T3 (es) * 2001-01-16 2005-07-16 Glaxo Group Limited Combinacion farmaceutica que contiene una 4-quinazolinamina y paclitaxel, carboplatino o vinorelbina para el tratamiento de cancer.
US20060204966A1 (en) * 2003-08-01 2006-09-14 Spector Neil L Treatment of cancers expressing p95 erbb2
KR20080014144A (ko) * 2003-08-18 2008-02-13 화이자 프로덕츠 인크. ｅｒｂＢ２ 항암제에 대한 투약 스케쥴

Also Published As

Publication number Publication date
IL183448A0 (en) 2007-09-20
NO20072668L (no) 2007-09-04
RU2007120462A (ru) 2009-01-20
AU2005313439A1 (en) 2006-06-15
WO2006061253A3 (en) 2006-11-16
CN101115499A (zh) 2008-01-30
BRPI0518619A2 (pt) 2008-11-25
KR20070098857A (ko) 2007-10-05
EP1824509A2 (en) 2007-08-29
WO2006061253A2 (en) 2006-06-15
MA29133B1 (fr) 2008-01-02
CA2589981A1 (en) 2006-06-15
JP2008523017A (ja) 2008-07-03
US20100028414A1 (en) 2010-02-04
GB0427131D0 (en) 2005-01-12

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