MX9604109A - Agente para disminuir la tension ocular. - Google Patents
Agente para disminuir la tension ocular.Info
- Publication number
- MX9604109A MX9604109A MX9604109A MX9604109A MX9604109A MX 9604109 A MX9604109 A MX 9604109A MX 9604109 A MX9604109 A MX 9604109A MX 9604109 A MX9604109 A MX 9604109A MX 9604109 A MX9604109 A MX 9604109A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- alkenyl
- ocular tension
- tension depressant
- cycloalkyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
Un agente que disminuye la tension ocular excelente y/o un agente terapéutico de glaucoma para gotas para los ojos que contiene un compuestos mostrado en lo siguiente, sus sales y/o sus ésteres (Ver Formula) [R1: Alquilo, alquenilo, un grupo de una formula R5-A-B- (R5: H, alquilo, cicloalquilo, acilo; A: 0, 5; B: Enlace sencillo, alquileno); R2: Alquilo, alquenilo, un grupo de una formula -C(R6)(R7)(R8)(R6: OH, alcoxi; R7, R8: H, alquilo, alquenilo, alquinilo, cicloalquilo, arilo, aralquilo), R3: COOH, un grupo de una formula -COH(R9)(R10) (R9, R10: H, alquilo sustituido opcionalmente); R4: COOH, COCOOH, tetrazol].
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4540494 | 1994-03-16 | ||
PCT/JP1995/000444 WO1995024902A1 (fr) | 1994-03-16 | 1995-03-16 | Reducteur de tension oculaire |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9604109A true MX9604109A (es) | 1997-09-30 |
Family
ID=12718322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9604109A MX9604109A (es) | 1994-03-16 | 1995-03-16 | Agente para disminuir la tension ocular. |
Country Status (20)
Country | Link |
---|---|
US (1) | US5925664A (es) |
EP (2) | EP0795326B1 (es) |
KR (1) | KR100211446B1 (es) |
CN (2) | CN1104898C (es) |
AT (2) | ATE206050T1 (es) |
AU (1) | AU684916B2 (es) |
CZ (1) | CZ284395B6 (es) |
DE (2) | DE69522955T2 (es) |
DK (2) | DK0795326T3 (es) |
ES (2) | ES2163501T3 (es) |
FI (2) | FI114897B (es) |
GR (1) | GR3036989T3 (es) |
HK (1) | HK1000551A1 (es) |
HU (1) | HUT74734A (es) |
MX (1) | MX9604109A (es) |
NO (1) | NO311068B1 (es) |
NZ (1) | NZ282485A (es) |
PT (2) | PT1110551E (es) |
RU (1) | RU2123847C1 (es) |
WO (1) | WO1995024902A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1198650C (zh) * | 1999-06-11 | 2005-04-27 | 三共株式会社 | 局部给药用眼压降低组合物 |
TWI290470B (en) * | 1999-12-01 | 2007-12-01 | Sankyo Co | The composition for treating glaucoma |
GR20000100281A (el) * | 2000-08-17 | 2002-05-24 | Ιωαννης Ματσουκας | Ανταγωνιστες του υποδοχεα της αγγεοτενσινης ιι και συνθετικες μεθοδοι για την θεραπεια της υπερτασης και καρδιοαγγειακων ασθενειων |
WO2002045748A1 (fr) * | 2000-12-05 | 2002-06-13 | Sankyo Company, Limited | Compositions d'abaissement de la tension oculaire pour administration topique |
CA2522318C (en) * | 2003-04-15 | 2011-09-13 | Sankyo Company Limited | Drug for preventing or treating angiogenic eye diseases |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
ZA875052B (en) * | 1986-07-11 | 1989-03-29 | Du Pont | Angiotensin ii receptor blocking imidazoles |
US4820843A (en) * | 1987-05-22 | 1989-04-11 | E. I. Du Pont De Nemours And Company | Tetrazole intermediates to antihypertensive compounds |
CA1338238C (en) * | 1988-01-07 | 1996-04-09 | David John Carini | Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids |
KR0163595B1 (ko) * | 1989-06-30 | 1998-12-01 | 미리암디, 메코너헤이 | 치환된 이미다졸 |
WO1991015206A1 (en) * | 1990-04-05 | 1991-10-17 | E.I. Du Pont De Nemours And Company | Treatment of glaucoma and ocular hypertension with imidazole angiotensin-ii receptor antagonists |
US5196444A (en) * | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
US5126342A (en) * | 1990-10-01 | 1992-06-30 | Merck & Co., Inc. | Imidazole angiotensin ii antagonists incorporating acidic functional groups |
US5616599A (en) * | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
IS1756B (is) * | 1991-02-21 | 2000-12-28 | Sankyo Company Limited | Hliðstæðuaðferð til framleiðslu 1-Biphenylmethylimidazole afleiða |
US5219856A (en) * | 1992-04-06 | 1993-06-15 | E. I. Du Pont De Nemours And Company | Angiotensin-II receptor blocking, heterocycle substituted imidazoles |
ATE199548T1 (de) * | 1992-06-02 | 2001-03-15 | Sankyo Co | 4-carboxyimidazolderivate als angiotensin-ii- antagonisten und ihre therapeutische verwendung |
US5310929A (en) * | 1992-08-06 | 1994-05-10 | E. I. Du Pont De Nemours And Company | Prodrugs of imidazole carboxylic acids as angiotensin II receptor antagonists |
CZ283315B6 (cs) * | 1992-12-17 | 1998-02-18 | Sankyo Company Limited | Bifenylové deriváty, způsob výroby a farmaceutické prostředky k léčení hypertense a srdečních onemocnění, které tyto deriváty obsahují |
CZ154994A3 (en) * | 1993-07-02 | 1995-09-13 | Senju Pharma Co | Visual hypotensive agent |
WO1995021609A1 (en) * | 1994-02-08 | 1995-08-17 | Ciba-Geigy Ag | Treatment of normotensive glaucoma with angiotensin ii antagonists |
-
1995
- 1995-03-16 WO PCT/JP1995/000444 patent/WO1995024902A1/ja active IP Right Grant
- 1995-03-16 DK DK95912428T patent/DK0795326T3/da active
- 1995-03-16 AT AT95912428T patent/ATE206050T1/de not_active IP Right Cessation
- 1995-03-16 MX MX9604109A patent/MX9604109A/es not_active IP Right Cessation
- 1995-03-16 CZ CZ962694A patent/CZ284395B6/cs not_active IP Right Cessation
- 1995-03-16 NZ NZ282485A patent/NZ282485A/en not_active IP Right Cessation
- 1995-03-16 AU AU19602/95A patent/AU684916B2/en not_active Ceased
- 1995-03-16 CN CN95193132A patent/CN1104898C/zh not_active Expired - Fee Related
- 1995-03-16 ES ES95912428T patent/ES2163501T3/es not_active Expired - Lifetime
- 1995-03-16 EP EP95912428A patent/EP0795326B1/en not_active Expired - Lifetime
- 1995-03-16 DK DK01102527T patent/DK1110551T3/da active
- 1995-03-16 PT PT01102527T patent/PT1110551E/pt unknown
- 1995-03-16 KR KR1019960705082A patent/KR100211446B1/ko not_active IP Right Cessation
- 1995-03-16 DE DE69522955T patent/DE69522955T2/de not_active Expired - Fee Related
- 1995-03-16 DE DE69533045T patent/DE69533045T2/de not_active Expired - Fee Related
- 1995-03-16 HU HU9602534A patent/HUT74734A/hu unknown
- 1995-03-16 PT PT95912428T patent/PT795326E/pt unknown
- 1995-03-16 AT AT01102527T patent/ATE266402T1/de not_active IP Right Cessation
- 1995-03-16 ES ES01102527T patent/ES2221872T3/es not_active Expired - Lifetime
- 1995-03-16 RU RU96121253A patent/RU2123847C1/ru active
- 1995-03-16 EP EP01102527A patent/EP1110551B1/en not_active Expired - Lifetime
-
1996
- 1996-09-13 NO NO19963854A patent/NO311068B1/no not_active IP Right Cessation
- 1996-09-16 US US08/725,197 patent/US5925664A/en not_active Expired - Fee Related
- 1996-09-16 FI FI963645A patent/FI114897B/fi active IP Right Grant
-
1997
- 1997-10-23 HK HK97102015A patent/HK1000551A1/xx not_active IP Right Cessation
-
2001
- 2001-10-24 GR GR20010401862T patent/GR3036989T3/el not_active IP Right Cessation
-
2002
- 2002-05-11 CN CNB021199396A patent/CN1202819C/zh not_active Expired - Fee Related
-
2004
- 2004-09-24 FI FI20041236A patent/FI115197B/fi active IP Right Grant
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |